Standout Papers
Citation Impact
Citing Papers
2014
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
2016 Science
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Autophagy Regulates Pancreatic Beta Cell Death in Response to Pdx1 Deficiency and Nutrient Deprivation
2009
Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
2009
Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy
2014
Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
2012
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Targeting autophagy in obesity: from pathophysiology to management
2018
Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition
2011
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
2009
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
2010
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
2009
nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
2016
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
2012
The Scaffold Protein Atg11 Recruits Fission Machinery to Drive Selective Mitochondria Degradation by Autophagy
2013
Dementia, stroke and migraine — Some common pathological mechanisms
2010
Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy
2009
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Mitophagy Contributes to the Pathogenesis of Inflammatory Diseases
2018
BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory
2015
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
2010
Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders
2017
Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
2011
Essential amino acids and glutamine regulate induction of mitochondrial elongation during autophagy
2011
Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice
2011
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
2010
Mitochondria and autophagy: Critical interplay between the two homeostats
2011
Mitochondrial fusion and fission in cell life and death
2010 Standout
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
2010
Autophagy: Renovation of Cells and Tissues
2011 Standout
IF1, the endogenous regulator of the F1Fo-ATPsynthase, defines mitochondrial volume fraction in HeLa cells by regulating autophagy
2009
Mitochondrial stress and the pathogenesis of diabetic neuropathy
2010
Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
2008
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Mechanisms of mitochondrial diseases
2011
Pancreatic Adenocarcinoma
2014 Standout
Mitochondrial dynamics in cell death and neurodegeneration
2010
Mitophagy in Yeast Occurs through a Selective Mechanism
2008
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
2011
Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
2009 StandoutNobel
Pancreatic cancers require autophagy for tumor growth
2011
PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
2011
Mitochondrial fragmentation in neurodegeneration
2008
PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy
2010
Parkinson's disease
2015 Standout
Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner
2012
The different shades of fat
2014 Nature
Mitochondrial dynamics and apoptosis
2008
The axonal transport of mitochondria
2012
Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA
2008
The molecular mechanism and cellular functions of mitochondrial division
2008
RNF185, a Novel Mitochondrial Ubiquitin E3 Ligase, Regulates Autophagy through Interaction with BNIP1
2011
SLP‐2 is required for stress‐induced mitochondrial hyperfusion
2009
Autophagy in Human Health and Disease
2013 Standout
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson’s disease
2013
Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy
2013
Mechanisms of mitophagy
2010 Standout
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Small Molecule Inhibitors of Mitochondrial Division: Tools that Translate Basic Biological Research into Medicine
2010
A simple ImageJ macro tool for analyzing mitochondrial network morphology in mammalian cell culture
2017
Methods in Mammalian Autophagy Research
2010 Standout
The Autophagy-related Protein Kinase Atg1 Interacts with the Ubiquitin-like Protein Atg8 via the Atg8 Family Interacting Motif to Facilitate Autophagosome Formation
2012 StandoutNobel
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
2010
Autophagy and Aging
2011 Standout
Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance
2014
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
2009
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
2009
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
2012
Dynamic regulation of mitochondrial fission through modification of the dynamin‐related protein Drp1
2010
Expanding perspectives on the significance of mitophagy in cancer
2017
UBE2N, UBE2L3 and UBE2D2/3 ubiquitin-conjugating enzymes are essential for parkin-dependent mitophagy
2014
Epigallocatechin Gallate (EGCG) Stimulates Autophagy in Vascular Endothelial Cells
2013
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
2013
What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy?
2009
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons
2012
Autophagy and pattern recognition receptors in innate immunity
2008
Mitochondria: The Next (Neurode)Generation
2011
Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy
2011
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The Hallmarks of Aging
2013 Standout
The PI3K Pathway in Human Disease
2017 Standout
Dynamics and diversity in autophagy mechanisms: lessons from yeast
2009 StandoutNobel
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
2009
Recent advances into the understanding of mitochondrial fission
2012
Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
2012 StandoutNobel
Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy
2013
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Inhibition of autophagy in the heart induces age-related cardiomyopathy
2010
Mitochondrial Diseases: Hope for the Future
2020
The evolution and role of mitochondrial fusion and fission in aging and disease
2011
Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming
2010
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Autophagy-related Protein 8 (Atg8) Family Interacting Motif in Atg3 Mediates the Atg3-Atg8 Interaction and Is Crucial for the Cytoplasm-to-Vacuole Targeting Pathway
2010 StandoutNobel
Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover
2010
Mechanisms and Biology of B-Cell Leukemia/Lymphoma 2/Adenovirus E1B Interacting Protein 3 and Nip-Like Protein X
2010
Mitochondrial Dynamics in Diabetes
2010
Mitochondria Autophagy in Yeast
2011
The Interplay Between Mitochondrial Dynamics and Mitophagy
2010
Mitochondrial Quality Control and Dynamics in Parkinson's Disease
2011
ULK1, Mammalian Target of Rapamycin, and Mitochondria: Linking Nutrient Availability and Autophagy
2011
Metabolic regulation of mitochondrial dynamics
2016
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 Standout
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
2010
Assessing mitochondrial dysfunction in cells
2011 Standout
Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance
2011
The evolution and role of mitochondrial fusion and fission in aging and disease.
2011
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Analysis of neural subtypes reveals selective mitochondrial dysfunction in dopaminergic neurons from parkin mutants
2012
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Beclin-1-Dependent Autophagy Protects the Heart During Sepsis
2018
How Mitochondrial Dynamism Orchestrates Mitophagy
2015
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
2011
Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage
2012
Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
2009
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants
2019 StandoutNobel
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
2010
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
2011
Autophagy During Cardiac Stress: Joys and Frustrations of Autophagy
2010
Mitochondrial Contagion Induced by Parkin Deficiency in Drosophila Hearts and Its Containment by Suppressing Mitofusin
2013
Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation
2010
Spermidine in health and disease
2018 StandoutScience
How to Live Long and Prosper: Autophagy, Mitochondria, and Aging
2008
A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy
2009
Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health
2011
Caspase-independent Mitochondrial Cell Death Results from Loss of Respiration, Not Cytotoxic Protein Release
2009
Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling
2015
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
2008
Cell Biology of the Mitochondrion
2017
The BH3‐only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms
2010
Murine Mesenchymal Stem Cell Commitment to Differentiation Is Regulated by Mitochondrial Dynamics
2015
Autophagy and Metabolism
2010 StandoutScience
Mitophagy
2009
α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
2010
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
2014
Mutations in Fis1 disrupt orderly disposal of defective mitochondria
2013
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
2014
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
2010
Minireview: Autophagy in Pancreatic β-Cells and Its Implication in Diabetes
2015
Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
2009
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Autophagy in health and disease. 5. Mitophagy as a way of life
2010
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy
2016
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
2008 Standout
Phosphorylation of Serine 114 on Atg32 mediates mitophagy
2011
Works of Guy Las being referenced
Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux
2017
Fatty Acids Suppress Autophagic Turnover in β-Cells
2011
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
2008 Standout
Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure
2014
Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis
2009
Biophysical properties of mitochondrial fusion events in pancreatic β-cells and cardiac cells unravel potential control mechanisms of its selectivity
2010