Citation Impact
Citing Papers
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac
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mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
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Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K + Ion Channel
2012 ScienceNobel
Deep Brain Stimulation for Treatment-Resistant Depression
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Medication Augmentation after the Failure of SSRIs for Depression
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Are Antidepressant Drugs That Combine Serotonergic and Noradrenergic Mechanisms of Action More Effective Than the Selective Serotonin Reuptake Inhibitors in Treating Major Depressive Disorder? A Meta-analysis of Studies of Newer Agents
2007
Involvement of the Endocannabinoid System in the Ability of Long-Term Tricyclic Antidepressant Treatment to Suppress Stress-Induced Activation of the Hypothalamic–Pituitary–Adrenal Axis
2006
Trial of Psilocybin versus Escitalopram for Depression
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Dehydroepiandrosterone Monotherapy in Midlife-Onset Major and Minor Depression
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Venlafaxine Extended-Release
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Ca2+–Zn2+ permeable AMPA or kainate receptors: possible key factors in selective neurodegeneration
2000
Depression
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Bupropion-SR, Sertraline, or Venlafaxine-XR after Failure of SSRIs for Depression
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Switching Antidepressants After a First Selective Serotonin Reuptake Inhibitor in Major Depressive Disorder
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Background and rationale for the Sequenced Treatment Alternatives to Relieve Depression (STAR∗D) study
2003
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
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Supply and demand for endocannabinoids
2011
Understanding Synapses: Past, Present, and Future
2008 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
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Mechanisms and Functional Implications of Adult Neurogenesis
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Memantine in Moderate-to-Severe Alzheimer's Disease
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Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia
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The mechano-gated K2P channel TREK-1
2008
Adverse Health Effects of Marijuana Use
2014 Standout
Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs
2004
Increased preproneuropeptide Y mRNA in the rat hippocampus during the development of hippocampal kindling: Comparison with the expression of preprosomatostatin mRNA
1991
Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α
2007 StandoutNobel
Antidepressants for the Treatment of Chronic Pain
2008
Serotonin-Norepinephrine Reuptake Inhibitors for Pain Control: Premise and Promise
2009
Neuroligin-2 Deletion Selectively Decreases Inhibitory Synaptic Transmission Originating from Fast-Spiking but Not from Somatostatin-Positive Interneurons
2009 StandoutNobel
Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
2008
Anxiolytic-Like Properties of the Anandamide Transport Inhibitor AM404
2006
Neuropeptide Y inhibits potassium‐stimulated glutamate release through Y2receptors in rat hippocampal slicesin vitro
1994
Molecular and Cellular Mechanisms of Antidepressant Action
2012
Glutamate receptors in the mammalian central nervous system
1998
The adolescent brain and age-related behavioral manifestations
2000 Standout
Dopamine D1, receptor ligands modulate cognitive performance and hippocampal acetylcholine release in memory-impaired aged rats
1995
Chapter 28 The glutamate synapse in neuropsychiatric disorders: Focus on schizophrenia and Alzheimer's disease
1998
Drugs, their targets and the nature and number of drug targets
2006
σ Receptors: potential medications development target for anti-cocaine agents
2003
A synaptic model of memory: long-term potentiation in the hippocampus
1993 StandoutNature
Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception
2014
Mechanically Activated Ion Channels
2015 StandoutNobel
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Molecular regulations governing TREK and TRAAK channel functions
2011
Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling
2013 StandoutNobel
σ-1 Receptors (σ1 Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export
2003
New approaches to antidepressant drug discovery: beyond monoamines
2006
Parkinson's disease
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Intracellular Dynamics of σ-1 Receptors (σ1 Binding Sites) in NG108-15 Cells
2003
??-1 Receptor Ligands
2004
Presynaptic Modulation by Endocannabinoids
2007
Deep brain stimulation for Parkinsonʼs disease and other movement disorders
2013
Elevated Monoamine Oxidase A Levels in the Brain
2006
Psychobiological Mechanisms of Resilience and Vulnerability: Implications for Successful Adaptation to Extreme Stress
2004
Regulation of Monoamine Oxidase A by Circadian-Clock Components Implies Clock Influence on Mood
2008
Major Depressive Disorder
2008 Standout
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels
2008 StandoutNobel
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Inhibition of Fatty-Acid Amide Hydrolase Accelerates Acquisition and Extinction Rates in a Spatial Memory Task
2006
Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands
1997
TASK-3 Two-Pore Domain Potassium Channels Enable Sustained High-Frequency Firing in Cerebellar Granule Neurons
2007
Dehydroepiandrosterone Augmentation in the Management of Negative, Depressive, and Anxiety Symptoms in Schizophrenia
2003
Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues
1992
Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats
1994
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
The neuronal background K2P channels: focus on TREK1
2007
The molecular neurobiology of depression
2008 StandoutNature
Pain-associated signals, acidosis and lysophosphatidic acid, modulate the neuronal K2P2.1 channel
2008
Glutamate Receptor Dysfunction and Schizophrenia
1995
Amyotrophic Lateral Sclerosis
2001 Standout
Neurosensory mechanotransduction
2008 StandoutNobel
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
The neurobiology of depression and antidepressant action
2012
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway
1999 StandoutNobel
Local modulation of hippocampal acetylcholine release by dopamine D1 receptors: a combined receptor autoradiography and in vivo dialysis study
1995
Pharmacological interventions for somatoform disorders in adults
2014 Standout
Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells
2002 StandoutNobel
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
Regulating ankyrin dynamics: Roles of sigma-1 receptors
2001
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
1996 StandoutNobel
The inositol 1,4,5‐trisphosphate pathway mediates cholinergic potentiation of rat hippocampal neuronal responses to NMDA.
1992
Optimization of α-Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase
2008
Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase
2012
Neuropeptides-immunoreactivity and their mRNA expression in kindling: functional implications for limbic epileptogenesis
1996
Molecular Background of Leak K+Currents: Two-Pore Domain Potassium Channels
2010
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Interneurons of the hippocampus
1998 Standout
Nongenomic Steroid Action: Controversies, Questions, and Answers
2003
Purification, molecular cloning, and expression of the mammalian sigma1-binding site.
1996
A FAAH-Regulated Class of N-Acyl Taurines That Activates TRP Ion Channels
2006 StandoutNobel
Autoradiographic analysis of neuropeptide Y receptor binding sites in the rat hippocampus after kainic acid-induced limbic seizures
1996
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Regulation of neurogenesis by growth factors and neurotransmitters
1998
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Detection of the toxin domoic acid from clam extracts using a portable surface plasmon resonance biosensor
2006
Increased baseline occupancy of D 2 receptors by dopamine in schizophrenia
2000 Standout
AMPA Exposures Induce Mitochondrial Ca2+Overload and ROS Generation in Spinal Motor NeuronsIn Vitro
2000
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
The Endocannabinoid System and the Brain
2012
How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2
2015
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Multiple Functions of Endocannabinoid Signaling in the Brain
2012
Works of Guy Debonnel being referenced
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis
2005
A multicenter pilot study of subcallosal cingulate area deep brain stimulation for treatment-resistant depression
2011
Differential physiological effects of a low dose and high doses of venlafaxine in major depression
2006
An index of 5-HT synthesis changes during early antidepressant treatment: α-[11C]methyl-l-tryptophan PET study
2007
Domoic acid, the alleged "mussel toxin," might produce its neurotoxic effect through kainate receptor activation: an electrophysiological study in the rat dorsal hippocampus
1989
Mirtazapine and paroxetine in major depression: A comparison of monotherapy versus their combination from treatment initiation
2009
In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by sigma ligands.
1992
Neuropeptide Y potentiates the N-methyl-D-aspartate response in the CA3 dorsal hippocampus. II. Involvement of a subtype of sigma receptor.
1992
Neuropeptide Y selectively potentiates N-methyl-D-aspartate-induced neuronal activation
1990
Some of the effects of the selective sigma ligand (+)pentazocine are mediated via a naloxone-sensitive receptor
2001
Modulation of nmda and dopaminergic neurotransmissions by sigma ligands: Possible implications for the treatment of psychiatric disorders
1996
Serotonin4 (5-HT4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action
2007
Blockade of 5‐Hydroxytryptamine and noradrenaline uptake by venlafaxine: a comparative study with paroxetine and desipramine
1998
In Vivo Modulation of Sigma Receptor Sites by Calcitonin Gene‐related Peptide in the Mouse and Rat Hippocampal Formation: Radioligand Binding and Electrophysiological Studies
1995
Biphasic effects of sigma ligands on the neuronal response to N-methyl-D-aspartate
1995
Measurement of Brain Regional α-[11C]Methyl-L-Tryptophan Trapping as a Measure of Serotonin Synthesis in Medication-FreePatients With Major Depression
2004
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype
2006
The effects of sigma ligands and of neuropeptide Y on N‐methyl‐d ‐aspartate‐induced neuronal activation of CA3 dorsal hippocampus neurones are differentially affected by pertussin toxin
1994
N-methyl-D-aspartate-induced neuronal activation is selectively modulated by σ receptors
1990
Cannabinoids Elicit Antidepressant-Like Behavior and Activate Serotonergic Neurons through the Medial Prefrontal Cortex
2007
Reduced neuroexcitatory effect of domoic acid following mossy fiber denervation of the rat dorsal hippocampus: further evidence that toxicity of domoic acid involves kainate receptor activation
1989
SIGMA LIGANDS AND NEUROPEPTIDE Y SELECTIVELY POTENTIATE THE NMDA RESPONSE IN THE RAT CA3 DORSAL HIPPOCAMPUS: IN VIVO ELECTROPHYSIOLOGICAL STUDIES.
1992
Modulation of serotonergic neurotransmission by short‐ and long‐term treatments with sigma ligands
2001
Potentiation by dehydroepiandrosterone of the neuronal response to N-methyl-D-aspartate in the CA3 region of the rat dorsal hippocampus: an effect mediated via sigma receptors.
1996
Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters
1998
Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors
1996
Neuropeptide Y potentiates selectively the N-methyl-D-aspartate response in the rat CA3 dorsal hippocampus. I. Involvement of an atypical neuropeptide Y receptor.
1992
Venlafaxine: Discrepancy between in vivo 5-HT and NE reuptake blockade and affinity for reuptake sites
1999
Effects of mirtazapine, paroxetine and their combination: a double-blind study in major depression
2000
Effects of long-term haloperidol treatment on the responsiveness of accumbens neurons to cholecystokinin and dopamine: electrophysiological and radioligand binding studies in the rat
1990
Venlafaxine in Treatment-Resistant Major Depression: A Canadian Multicenter, Open-Label Trial
1999