Citation Impact
Citing Papers
Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.
2013
Developmental refinement of hair cell synapses tightens the coupling of Ca 2 + influx to exocytosis
2014 StandoutNobel
LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
2018
Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell
2018
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases
2020 StandoutNobel
Long COVID: major findings, mechanisms and recommendations
2023 Standout
Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice
2011
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
Early endosome localization and activity of RasGEF1b, a toll-like receptor-inducible Ras guanine-nucleotide exchange factor
2010
Norepinephrine Increases Glucose Transport in Brown Adipocytes via β3-Adrenoceptors through a cAMP, PKA, and PI3-Kinase-Dependent Pathway Stimulating Conventional and Novel PKCs
2003
Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes
2016
Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1
2019
Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells
2003
Proteostasis and “redoxtasis” in the secretory pathway: Tales of tails from ERp44 and immunoglobulins
2015
Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α
2007 StandoutNobel
Mechanosensory hair cells express two molecularly distinct mechanotransduction channels
2016 StandoutNobel
Presynaptic Mechanism Underlying cAMP-Dependent Synaptic Potentiation
2004
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
The metabolic syndrome
2010 Standout
Oxidative Stress in Neurodegenerative Diseases
1996
Regulation of Insulin Secretion in Islets of Langerhans by Ca2+Channels
2004
Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines
2009
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
The biology of incretin hormones
2006 Standout
Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome
2021
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis
2020
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The metabolic syndrome
2005 Standout
Glucagon-like Peptide-2 Receptor Activation Engages Bad and Glycogen Synthase Kinase-3 in a Protein Kinase A-dependent Manner and Prevents Apoptosis following Inhibition of Phosphatidylinositol 3-Kinase
2002
PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase‐3β in osteoblastic Saos‐2 cells
2007 StandoutNobel
Biology of Incretins: GLP-1 and GIP
2007 Standout
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
Free Fatty Acid-induced β-Cell Defects Are Dependent on Uncoupling Protein 2 Expression
2004
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Imaging second messenger dynamics in developing neural circuits
2008
Stress signalling pathways that impair prefrontal cortex structure and function
2009 Standout
Optical Control of Insulin Secretion Using an Incretin Switch
2015
The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Failure
2022
Septins Regulate Developmental Switching from Microdomain to Nanodomain Coupling of Ca2+ Influx to Neurotransmitter Release at a Central Synapse
2010
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
International Union of Pharmacology. XXXV. The Glucagon Receptor Family
2003
A pancreatic islet-specific microRNA regulates insulin secretion
2004 StandoutNature
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity
2004
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
2016 StandoutNobel
PKA-Dependent and PKA-Independent Pathways for cAMP-Regulated Exocytosis
2005
Oxidative Stress in Cancer
2020 Standout
GLP-1 Mediates Antiapoptotic Effect by Phosphorylating Bad through a β-Arrestin 1-mediated ERK1/2 Activation in Pancreatic β-Cells
2009
Activation of apoptosis signalling pathways by reactive oxygen species
2016 Standout
The Physiology of Glucagon-like Peptide 1
2007 Standout
The antioxidant machinery of the endoplasmic reticulum: Protection and signaling
2015
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
A role for Piezo2 in EPAC1-dependent mechanical allodynia
2013
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles
2008 Standout
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
2020 StandoutNobel
Activation of PKA and Epac proteins by cyclic AMP depletes intracellular calcium stores and reduces calcium availability for vasoconstriction
2016
cAMP Dose-dependently Prevents Palmitate-induced Apoptosis by Both Protein Kinase A- and cAMP-Guanine Nucleotide Exchange Factor-dependent Pathways in β-Cells
2004
Epac proteins: multi-purpose cAMP targets
2006
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
cAMP Acts on Exchange Protein Activated by cAMP/cAMP-Regulated Guanine Nucleotide Exchange Protein to Regulate Transmitter Release at the Crayfish Neuromuscular Junction
2005
Ero1α Regulates Ca 2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)
2011
Redox Mechanisms in Neurodegeneration: From Disease Outcomes to Therapeutic Opportunities
2018
Glucagon-Like Peptide 1 Induces Pancreatic β-Cell Proliferation Via Transactivation of the Epidermal Growth Factor Receptor
2003
Epac: A New cAMP-Binding Protein in Support of Glucagon-Like Peptide-1 Receptor-Mediated Signal Transduction in the Pancreatic β-Cell
2004
Epac: Defining a New Mechanism for cAMP Action
2010
Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release
2006 StandoutNobel
Tirzepatide Once Weekly for the Treatment of Obesity
2022 Standout
Regulatory T Cells and Human Disease
2020 StandoutNobel
Transcription Factor FoxO1 Mediates Glucagon-Like Peptide-1 Effects on Pancreatic β-Cell Mass
2006
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
The Ryanodine Receptor Calcium Channel of β-Cells
2002
Insulin secretion from beta cells within intact islets: Location matters
2015
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activated Protein Kinase
2003
Molecular control of regulatory T cell development and function
2017 StandoutNobel
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice
2018 StandoutNobel
The Cyclic AMP-Epac1-Rap1 Pathway Is Dissociated from Regulation of Effector Functions in Monocytes but Acquires Immunoregulatory Function in Mature Macrophages
2006
Optische Kontrolle der Insulinsekretion mit einem Inkretinschalter
2015
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Micromanaging insulin secretion
2004 StandoutNobel
Serotonin Receptors
2008
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Imaging the glycome
2008 StandoutNobel
Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells
2003
cAMP-Activated Protein Kinase-Independent Potentiation of Insulin Secretion by cAMP Is Impaired in SUR1 Null Islets
2002
Emerging Targets in Photopharmacology
2016 StandoutNobel
Does Rap1 deserve a bad Rap?
2003
Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men
2017
Glucagon-Like Peptides: Regulators of Cell Proliferation, Differentiation, and Apoptosis
2003
Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling
2007 Standout
Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes
2012
Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation
2005 StandoutNobel
SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells
2003
Proglucagon-Derived Peptides: Mechanisms of Action and Therapeutic Potential
2005
Works of Guoxin Kang being referenced
Epac-selective cAMP Analog 8-pCPT-2′-O-Me-cAMP as a Stimulus for Ca2+-induced Ca2+ Release and Exocytosis in Pancreatic β-Cells
2003
A cAMP and Ca2+ coincidence detector in support of Ca2+‐induced Ca2+ release in mouse pancreatic β cells
2005
Cell physiology of cAMP sensor Epac
2006
Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity
2017
Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells
2011
Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic β‐cells and rat INS‐1 cells
2008
Relationships among Cortical Glutathione Levels, Brain Amyloidosis, and Memory in Healthy Older Adults Investigated In Vivo with1H-MRS and Pittsburgh Compound-B PET
2017
Amplification of exocytosis by Ca2+‐induced Ca2+ release in INS‐1 pancreatic β cells
2003
Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice
2009
cAMP‐regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+‐induced Ca2+ release in INS‐1 pancreatic β‐cells
2001
Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice
2009
Motor cortex glutathione deficit in ALS measured in vivo with the J-editing technique
2014
GATA factors efficiently direct cardiac fate from embryonic stem cells
2013
cAMP sensor Epac as a determinant of ATP‐sensitive potassium channel activity in human pancreatic β cells and rat INS‐1 cells
2006
Elevations of ventricular lactate levels occur in both chronic fatigue syndrome and fibromyalgia
2017
The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation‐coupled calcium release and response to hemodynamic load
2011