Citation Impact
Citing Papers
LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
2003
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
2005
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
2005
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling
2005
Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I
2005
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1 -deficient mouse embryonic fibroblasts
2003
Essential role of IPS-1 in innate immune responses against RNA viruses
2006
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I
2005
Cutting Edge: Roles of Caspase-8 and Caspase-10 in Innate Immune Responses to Double-Stranded RNA
2006
The Tpl2 Mutation Sluggish Impairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease
2009 StandoutNobel
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
Regulation of IκB Kinase-related Kinases and Antiviral Responses by Tumor Suppressor CYLD
2008
Interferon‐regulatory‐factor 1 controls Toll‐like receptor 9‐mediated IFN‐β production in myeloid dendritic cells
2007
IRF-7 is the master regulator of type-I interferon-dependent immune responses
2005 StandoutNature
IKKi/IKKϵ Plays a Key Role in Integrating Signals Induced by Pro-inflammatory Stimuli
2003
RNA recognition and signal transduction by RIG‐I‐like receptors
2008
Inflammation and metabolic disorders
2006 StandoutNature
X-ray crystal structure of IRF-3 and its functional implications
2003
Regulation of the type I IFN induction: a current view
2005
Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
2016 Standout
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Mechanisms of Disease: leukotrienes and lipoxins in scleroderma lung disease—insights and potential therapeutic implications
2007
The NEMO adaptor bridges the nuclear factor-κB and interferon regulatory factor signaling pathways
2007
Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA
2006
Evasion of intracellular host defence by hepatitis C virus
2005 Nature
Cell Type-Specific Involvement of RIG-I in Antiviral Response
2005
Identification of a TLR4‐ and TRIF‐dependent activation program of dendritic cells
2004 StandoutNobel
TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway
2003
Functional Characterization of Murine Interferon Regulatory Factor 5 (IRF-5) and Its Role in the Innate Antiviral Response
2008
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA
2005
RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation
2004
The roles of TLRs, RLRs and NLRs in pathogen recognition
2009
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
2004
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
2008 Standout
Toll-like receptors in innate immunity
2004 Standout
Glucocorticoids Inhibit IRF3 Phosphorylation in Response to Toll-like Receptor-3 and -4 by Targeting TBK1 Activation
2008
Intracellular Toll-like Receptors
2010 StandoutNobel
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
NLRX1 is a regulator of mitochondrial antiviral immunity
2008 Nature
Toll-like receptor signalling
2004 Standout
Type I interferon production by nucleic acid-stimulated dendritic cells
2008
Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation
2003
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
The Lipoxin Receptor ALX: Potent Ligand-Specific and Stereoselective Actions in Vivo
2006
IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9
2006 Nature
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
2005 Standout
TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β
2003
Induction of Protein Kinase PKR-dependent Activation of Interferon Regulatory Factor 3 by Vaccinia Virus Occurs through Adapter IPS-1 Signaling
2008
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
2004 Standout
Modulation of the Interferon Antiviral Response by the TBK1/IKKi Adaptor Protein TANK
2007
A FADD-dependent innate immune mechanism in mammalian cells
2004 Nature
Innate immune recognition of viral infection
2006 Standout
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
2005 Nature
TLR signaling
2007
VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling
2005 Standout
Origin and physiological roles of inflammation
2008 StandoutNature
The Interferon Regulatory Factor, IRF5, Is a Central Mediator of Toll-like Receptor 7 Signaling
2005
Toll-like receptors and innate antiviral responses
2003
Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-κB activation
2005
Innate immune recognition of nucleic acids: Beyond toll-like receptors
2005
Signaling to NF-κB
2004 Standout
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
2006 StandoutNature
Mechanisms of the TRIF-induced Interferon-stimulated Response Element and NF-κB Activation and Apoptosis Pathways
2004
Manipulation of the nuclear factor-κB pathway and the innate immune response by viruses
2006
Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3
2005 Standout
Reading the viral signature by Toll-like receptors and other pattern recognition receptors
2005
The Yin and Yang of type I interferon activity in bacterial infection
2005
Toll-like receptors and innate immunity
2009
Identification of Ser-386 of Interferon Regulatory Factor 3 as Critical Target for Inducible Phosphorylation That Determines Activation
2004
TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway
2008
Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism
2003
Convergence of the NF‐κB and Interferon Signaling Pathways in the Regulation of Antiviral Defense and Apoptosis
2003
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Pathogen Recognition and Innate Immunity
2006 Standout
Signaling to NF-κB by Toll-like receptors
2007 Standout
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Lipoxin A 4 Inhibits Proliferation of Human Lung Fibroblasts Induced by Connective TissueGrowth Factor
2005
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection
2004
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
Differential Requirement for TANK-binding Kinase-1 in Type I Interferon Responses to Toll-like Receptor Activation and Viral Infection
2004
Effects of Nonstructural Proteins NS1 and NS2 of Human Respiratory Syncytial Virus on Interferon Regulatory Factor 3, NF-κB, and Proinflammatory Cytokines
2005
Shared and Unique Functions of the DExD/H-Box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate Immunity
2005
Transforming Growth Factor β/Smad3 Signaling Regulates IRF-7 Function and Transcriptional Activation of the Beta Interferon Promoter
2004
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Inhibition of RIG-I-Dependent Signaling to the Interferon Pathway during Hepatitis C Virus Expression and Restoration of Signaling by IKKε
2005
Activation of TBK1 and IKKε Kinases by Vesicular Stomatitis Virus Infection and the Role of Viral Ribonucleoprotein in the Development of Interferon Antiviral Immunity
2004
Cutting Edge: NF-κB-Activating Kinase-Associated Protein 1 Participates in TLR3/Toll-IL-1 Homology Domain-Containing Adapter Molecule-1-Mediated IFN Regulatory Factor 3 Activation
2005
cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection
2016
Transcriptional Activation of Alpha/Beta Interferon Genes: Interference by Nonsegmented Negative-Strand RNA Viruses
2005
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Ebola Virus VP35 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-I Signaling
2006
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Essential role of IRF-3 in lipopolysaccharide-induced interferon-β gene expression and endotoxin shock
2003
Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN-β (TRIF) Associates with TNF Receptor-Associated Factor 6 and TANK-Binding Kinase 1, and Activates Two Distinct Transcription Factors, NF-κB and IFN-Regulatory Factor-3, in the Toll-Like Receptor Signaling
2003
TLR-Independent Induction of Dendritic Cell Maturation and Adaptive Immunity by Negative-Strand RNA Viruses
2004
West Nile Virus Evades Activation of Interferon Regulatory Factor 3 through RIG-I-Dependent and -Independent Pathways without Antagonizing Host Defense Signaling
2006
Immune Activation of Type I IFNs by Listeria monocytogenes Occurs Independently of TLR4, TLR2, and Receptor Interacting Protein 2 but Involves TANK-Binding Kinase 1
2005
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Toll-Like Receptor Signaling Pathways
2003 Science
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
2013
Regulation of IFN Regulatory Factor-7 and IFN-α Production by Enveloped Virus and Lipopolysaccharide in Human Plasmacytoid Dendritic Cells
2004
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
The Herpes Simplex Virus ICP0 RING Finger Domain Inhibits IRF3- and IRF7-Mediated Activation of Interferon-Stimulated Genes
2004
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Inhibition of Toll-Like Receptor 7- and 9-Mediated Alpha/Beta Interferon Production in Human Plasmacytoid Dendritic Cells by Respiratory Syncytial Virus and Measles Virus
2005
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction
2005
Regulation and Function of IKK and IKK-Related Kinases
2006
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β
2004
Resolution Phase of Inflammation: Novel Endogenous Anti-Inflammatory and Proresolving Lipid Mediators and Pathways
2006
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN -β promoter
2004
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Guoping Zhou being referenced
Lipoxin A4 inhibits TNF-α-induced production of interleukins and proliferation of rat mesangial cells
2005
High dose of lipoxin A4 induces apoptosis in rat renal interstitial fibroblasts
2005
Lipoxin A4 inhibits connective tissue growth factor-induced production of chemokines in rat mesangial cells
2006
Triggering the Interferon Antiviral Response Through an IKK-Related Pathway
2003 Science