Citation Impact
Citing Papers
Chaperone Suppression of α-Synuclein Toxicity in a Drosophila Model for Parkinson's Disease
2002 StandoutScience
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation
2001 StandoutNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Evolutionary History of a Specialized P450 Propane Monooxygenase
2008 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues
1994
Multiple cycles of global unfolding of GroEL-bound cyclophilin A evidenced by NMR
1997 StandoutNobel
H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
1994 Standout
Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases
2000
Human glutathione S-transferases
1994
A thermodynamic coupling mechanism can explain the GroEL-mediated acceleration of the folding of barstar11Edited by C. R. Matthews
2000
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
2002 StandoutNature
The amino acid sequence of glutathione transferase from Proteus mirabilis, a prototype of a new class of enzymes
1993
A Semisynthetic Glutathione Peroxidase with High Catalytic Efficiency
2002
The three-dimensional structure of a glutathione S-transferase from the Mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-.ANG. resolution
1992
The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex
1997 Nature
Analysis of GroE-assisted Folding under Nonpermissive Conditions
1999
Amino Acid Differences at Positions 10, 11, and 104 Explain the Profound Catalytic Differences between Two Murine Pi-Class Glutathione S-Transferases
1995
Investigations of the pathways of toxicity of methyl iodide in the rat nasal cavity
1998
Structure and function of glutathione S-transferases
1994
The Degradation of Apolipoprotein B100 Is Mediated by the Ubiquitin-proteasome Pathway and Involves Heat Shock Protein 70
1997 StandoutNobel
Microbial glutathione S-transferases
1993
Contribution of two conserved glycine residues to fibrillogenesis of the 106–126 prion protein fragment. Evidence that a soluble variant of the 106–126 peptide is neurotoxic
2003
GroEL/GroES: Structure and Function of a Two-Stroke Folding Machine
1998
GroEL recognises sequential and non-sequential linear structural motifs compatible with extended β-strands and α-helices 1 1Edited by J. Karn
1999
Protein Translocation
1999 StandoutNobel
Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions
2011
The Hsp70 and Hsp60 Chaperone Machines
1998 Standout
GroEL/GroES-Mediated Folding of a Protein Too Large to Be Encapsulated
2001
A Trimeric Protein Complex Functions as a Synaptic Chaperone Machine
2001 StandoutNobel
A subgroup of class α glutathione S‐transferases Cloning of cDNA for mouse lung glutathione S‐transferase GST 5.7
1992
Unnatural amino acids as probes of protein structure and function
2000
A Molecular Genetic Approach for the Identification of Essential Residues in Human Glutathione S-Transferase Function in Escherichia coli
1995
Contribution of amino acid residue 208 in the hydrophobic binding site to the catalytic mechanism of human glutathione transferase A1-1
1994
Protein folding and misfolding
2003 StandoutNature
Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22
1995
Glutathione S‐Transferases: Structure and Mechanism of an Archetypical Detoxication Enzyme
1994
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
GroEL-Mediated Protein Folding: Making the Impossible, Possible
2006
Two conformational states of β-lactamase bound to GroEL: a biophysical characterization 1 1Edited by A. R. Fersht
1998
Binding, encapsulation and ejection: substrate dynamics during a chaperonin-assisted folding reaction
1997
NMR analysis of a 900K GroEL–GroES complex
2002 StandoutNatureNobel
GroEL accelerates the refolding of hen lysozyme without changing its folding mechanism.
1999
Molecular chaperones in cellular protein folding
1996 StandoutNature
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Multistep mechanism of substrate binding determines chaperone activity of Hsp70.
2000
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents
2015
Proteins encoded by an auxin-regulated gene family of tobacco share limited but significant homology with glutathione S-transferases and one member indeed shows in vitro GST activity
1993
Folding of malate dehydrogenase inside the GroEL-GroES cavity.
2001
How Evolutionary Pressure Against Protein Aggregation Shaped Chaperone Specificity
2005
Review: Mechanisms of Disaggregation and Refolding of Stable Protein Aggregates by Molecular Chaperones
2001
Phage-display technology – finding a needle in a vast molecular haystack
1999
A surprising simplicity to protein folding
2000 StandoutNatureNobel
The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I
1995 Standout
Molecular Mechanism of Protein Folding in the Cell
2011 StandoutNobel
Multivalent Binding of Nonnative Substrate Proteins by the Chaperonin GroEL
2000
Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress
1999
NMR analysis of the binding of a rhodanese peptide to a minichaperone in solution 1 1Edited by J. Karn
1999
Mechanisms of protein folding
2001 StandoutNobel
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn
1999 StandoutNobel
Simple Physical Models Connect Theory and Experiment in Protein Folding Kinetics
2002 StandoutNobel
The chaperonin GroEL binds to late-folding non-native conformations present in native Escherichia coli and murine dihydrofolate reductases 1 1Edited by P. E. Wright
1999
The contribution of the C-terminal sequence to the catalytic activity of GST2, a human Alpha-class glutathione transferase
1991
Detoxication of base propenals and other alpha,beta-unsaturated aldehyde products of radical reactions and lipid peroxidationby human glutathione transferases.
1994
Efficient and Selective Palladium‐Catalysed C‐3 Urea Couplings to 3,5‐Dichloro‐2(1H)‐pyrazinones
2015
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70
2000 StandoutNobel
The Lumenal Domain of Sec63p Stimulates the ATPase Activity of BiP and Mediates BiP Recruitment to the Translocon in Saccharomyces cerevisiae
1997 StandoutNobel
Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase P1-1
1992
Chaperone activity and structure of monomeric polypeptide binding domains of GroEL
1996
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
A structural model for GroEL–polypeptide recognition
1997
Glutathione S‐transferases: Amino acid sequence comparison, classification and phylogenetic relationship
1992
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Squid glutathione S-transferase. Relationships with other glutathione S-transferases and S-crystallins of cephalopods.
1993
Mechanism-Based Phage Display Selection of Active-Site Mutants of Human Glutathione Transferase A1-1 Catalyzing SNAr Reactions
1997
Secondary Structure Forming Propensity Coupled with Amphiphilicity Is an Optimal Motif in a Peptide or Protein for Association with Chaperonin 60 (GroEL)
1999
Solution structure of p53 core domain: Structural basis for its instability
2006
Human glutathione transferase A4-4: an Alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation
1998
Chaperonin Function: Folding by Forced Unfolding
1999 Science
The glutathione S-transferase D genes. A divergently organized, intronless gene family in Drosophila melanogaster
1993
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Significant hydrogen exchange protection in GroEL‐bound DHFR is maintained during iterative rounds of substrate cycling
1996
Contribution of tyrosine 6 to the catalytic mechanism of isoenzyme 3-3 of glutathione S-transferase.
1992
Solution NMR Techniques for Large Molecular and Supramolecular Structures
2002 StandoutNobel
Catalysis, Commitment and Encapsulation during GroE-mediated Folding
1999
Drug Discovery: A Historical Perspective
2000 StandoutScience
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
Contribution of Aromatic−Aromatic Interactions to the Anomalous pKa of Tyrosine-9 and the C-Terminal Dynamics of Glutathione S-Transferase A1-1
2001
Artificial Molecular Machines
2000 StandoutNobel
Estimation of genomic complexity, heterologous expression, and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5.7).
1994
Chaperone-Mediated Protein Folding
1999
Chaperonin-Mediated Protein Folding
2001
Basis of Substrate Binding by the Chaperonin GroEL
1999
NMR solution structure of the human prion protein
2000 StandoutNobel
Nuclear Import and the Evolution of a Multifunctional RNA-binding Protein
1998 StandoutNobel
Design of two chimaeric human-rat class alpha glutathione transferases for probing the contribution of C-terminal segments of protein structure to the catalytic properties
1992
Crystal structure of a theta-class glutathione transferase.
1995
A thermodynamic coupling mechanism for GroEL-mediated unfolding.
1996
Participation of the phenolic hydroxyl group of Tyr-8 in the catalytic mechanism of human glutathione transferase P1-1
1992
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
STRUCTURE AND FUNCTION IN GroEL-MEDIATED PROTEIN FOLDING
1998
Chaperone rings in protein folding and degradation
1999
Cloning of cDNAs from fetal rat liver encoding glutathione S-transferase Yc polypeptides. The Yc2 subunit is expressed in adult rat liver resistant to the hepatocarcinogen aflatoxin B1.
1994
Receptor-Mediated Uptake of Antigen/Heat Shock Protein Complexes Results in Major Histocompatibility Complex Class I Antigen Presentation via Two Distinct Processing Pathways
1999 StandoutNobel
Synthesis and Characterization of a Series of Highly Fluorogenic Substrates for Glutathione Transferases, a General Strategy
2011
Proteinfaltung aus theoretischer und experimenteller Sicht
1998
Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding
2008
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Complete sequence of the bithorax complex of Drosophila.
1995 StandoutNobel
Molecular cloning and site-directed mutagenesis of glutathione S-transferase from Escherichia coli. The conserved tyrosyl residue near the N terminus is not essential for catalysis.
1994
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
Site-directed mutagenesis of glutathione S-transferase YaYa. Mapping the glutathione-binding site.
1993
Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action
2005 StandoutNobel
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle
2011 StandoutNobel
Evidence for an essential serine residue in the active site of the Theta class glutathione transferases
1995
Mass spectrometric analysis of rat liver cytosolic glutathione S-transferases: modifications are limited to N-terminal processing
1995
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Chemical Implications for Antitumor and Antiviral Prostaglandins: Reaction of Δ7-Prostaglandin A1 and Prostaglandin A1 Methyl Esters with Thiols
1997 StandoutNobel
Works of Gun Stenberg being referenced
An evolutionary approach to the design of glutathione-linked enzymes
1998
Importance of electrostatic interactions in the rapid binding of polypeptides to GroEL 1 1Edited by J. Karn
1997
The Folding and Stability of Human Alpha Class Glutathione Transferase A1-1 Depend on Distinct Roles of a Conserved N-capping Box and Hydrophobic Staple Motif
2001
High-Level Bacterial Expression of Human Glutathione Transferase P1-1 Encoded by Semisynthetic DNA
1995
Heterologous expression of recombinant human glutathione transferase A1-1 from a hepatoma cell line
1992
The Conserved N-capping Box in the Hydrophobic Core of Glutathione S-Transferase P1–1 Is Essential for Refolding
1997
Expression and purification of recombinant full-length NS3 protease–helicase from a new variant of Hepatitis C virus
2002
Functional significance of arginine 15 in the active site of human class alpha glutathione transferase A1-1
1995
Mutation of an evolutionarily conserved tyrosine residue in the active site of a human class Alpha glutathione transferase
1991
Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105
1998
Folding of barnase in the presence of the molecular chaperone SecB
1997
Heterologous expression, purification and characterization of rat class theta glutathione transferase T2-2
1996
Cloning and heterologous expression of cDNA encoding class Alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic α,β-unsaturated carbonyl compounds
1992
Catalysis of Amide Proton Exchange by the Molecular Chaperones GroEL and SecB
1996 Science
Analysis of the Role of the Active Site Tyrosine in Human Glutathione Transferase A1-1 by Unnatural Amino Acid Mutagenesis
1998
Effects of directed mutagenesis on conserved arginine residues in a human Class Alpha glutathione transferase
1991