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Citing Papers
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1975
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Epidermal growth factor receptor, platelet-derived growth factor receptor, and c-erbB-2 receptor activation all promote growth but have distinctive effects upon mouse mammary epithelial cell differentiation.
1991
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1992
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The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA
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Detection of platelet-derived growth factor (PDGF)-AA in actively healing human wounds treated with recombinant PDGF-BB and absence of PDGF in chronic nonhealing wounds.
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Rat Brain Capillary Endothelial Cells Express Functional PDGF B-Type Receptors
1989
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Production of cell-associated PDGF-AA by a human sarcoma cell line: evidence for a latent autocrine effect
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Response to Imatinib Mesylate in Patients with Chronic Myeloproliferative Diseases with Rearrangements of the Platelet-Derived Growth Factor Receptor Beta
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Activated platelet‐derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line
1994
Regulation of PDGF and its receptors in fibrotic diseases
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Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
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Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes.
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2001
Hypoxia signalling in cancer and approaches to enforce tumour regression
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Protein modules and signalling networks
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PDGF‐a/PDGF alpha‐receptor signaling is required for lung growth and the formation of alveoli but not for early lung branching morphogenesis
2001
Degradation Process of Ligand-stimulated Platelet-derived Growth Factor β -Receptor Involves Ubiquitin-Proteasome Proteolytic Pathway
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2004
Molecular regulation of angiogenesis and lymphangiogenesis
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2011
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Mechanistic aspects of enzymatic carbohydrate epimerization
2002
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A Unique Autophosphorylation Site in the Platelet‐Derived Growth Factor α Receptor from a Heterodimeric Receptor Complex
1994
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2000
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2004
Sox18 induces development of the lymphatic vasculature in mice
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2001
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1992
Interaction of heparin and antithrombin III
1988
Substrate Specificity of Heparanases from Human Hepatoma and Platelets
1998
Platelet-Derived Growth Factor B-Chain of Hematopoietic Origin Is Not Necessary for Granulation Tissue Formation and Its Absence Enhances Vascularization
2001
Expression analysis of PDGF-C in adult and developing mouse tissues
2002
Comprehensive Dissection of PDGF-PDGFR Signaling Pathways in PDGFR Genetically Defined Cells
2008
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2007
Reversal of experimental pulmonary hypertension by PDGF inhibition
2005
Pericytes regulate the blood–brain barrier
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2001
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2005
Blockade of Platelet-Derived Growth Factor or Its Receptors Transiently Delays but Does Not Prevent Fibrous Cap Formation in ApoE Null Mice
2002
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2004
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2003
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2010
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2008
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Specific effects of platelet derived growth factor (PDGF) on fetal rat and human dopaminergic neurons in vitro
1995
Fetal Lung Epithelial Cells Express Receptors for Platelet-derived Growth Factor
1993
Structure-activity relationship in heparin: A synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity
1983
Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF.
1991
Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB.
1993
The anticoagulant activation of antithrombin by heparin
1997
Platelet-Derived Growth Factor Receptor-α in Ventricular Zone Cells and in Developing Neurons
2001
Characterization of the retention motif in the C-terminal part of the long splice form of platelet-derived growth factor A-chain.
1994
Spectrum of Activity and Mechanism of Action of VEGF/PDGF Inhibitors
2007
Conversion of antithrombin from an inhibitor of thrombin to a substrate with reduced heparin affinity and enhanced conformational stability by binding of a tetradecapeptide corresponding to the P1 to P14 region of the putative reactive bond loop of the inhibitor.
1992
A specific requirement for PDGF-C in palate formation and PDGFR-α signaling
2004
Peripheral mural cell recruitment requires cell-autonomous heparan sulfate
2009
Guidance of mesoderm cell migration in theXenopusgastrula requires PDGF signaling
2004
Heparan sulphate requirement in platelet-derived growth factor B-mediated pericyte recruitment
2006
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
1997 StandoutScience
Mechanism of Acceleration of Antithrombin-Proteinase Reactions by Low Affinity Heparin
1995
Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor.
1994
β-d -xylosides and their analogues as artificial initiators of glycosaminoglycan chain synthesis. Aglycone-related variation in their effectiveness in vitro and in ovo
1987 StandoutNobel
Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis
2009
Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma.
1992
Serpin Structure, Mechanism, and Function
2002 Standout
Generation and Characterization of rgs5 Mutant Mice
2008
Synthesis and conformational analysis of an analogue of the antithrombin‐binding region of heparin: The role of the carboxylate function of α‐L‐idopyranuronate
1987
Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.
1992
Force field parameters for sulfates and sulfamates based onab initiocalculations: Extensions of AMBER and CHARMm fields
1995
Biosynthesis of heparin. The d -glucuronosyl- and N-acetyl-d -glucosaminyltransferase reactions and their relation to polymer modification
1992
Identification of a hydrophobic region in the carboxyl terminus of the platelet-derived growth factor beta-receptor which is important for ligand-mediated endocytosis.
1991
Identification of a cell retention signal in the B-chain of platelet-derived growth factor and in the long splice version of the A-chain.
1991
Die ersten synthetischen Kohlenhydrate mit den vollständigen antikoagulierenden Eigenschaften von Heparin
1998
STRUCTURAL STUDIES ON A BIOLOGICALLY ACTIVE HEXASACCHARIDE OBTAINED FROM HEPARIN
1981
PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (O-2A) cell lineage
1989
Angiopoietin-2 Causes Pericyte Dropout in the Normal Retina
2004
The structure of heparin oligosaccharide fragments with high anti-(factor Xa) activity containing the minimal antithrombin III-binding sequence Chemical and13C nuclear-magnetic-resonance studies
1981
Chemical Glycobiology
2001 StandoutScienceNobel
Platelet-Derived Growth Factor Production by B16 Melanoma Cells Leads to Increased Pericyte Abundance in Tumors and an Associated Increase in Tumor Growth Rate
2004
Accumulation of PDGF B and cell-binding forms of PDGF A in the extracellular matrix.
1993
Conformational analysis of synthetic heparin‐like oligosaccharides containing α‐L‐idopyranosyluronic acid
1987
Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors
1997 StandoutScience
A tyrosine residue in the juxtamembrane segment of the platelet-derived growth factor beta-receptor is critical for ligand-mediated endocytosis.
1994
Biosynthesis of heparin. O-sulfation of D-glucuronic acid units.
1990
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Effect of heparin on the glia-derived-nexin-thrombin interaction
1989
Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate
2002
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Notch3 Is Critical for Proper Angiogenesis and Mural Cell Investment
2010
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities
2004
Endothelial/Pericyte Interactions
2005 Standout
Platelet-Derived Growth Factor D Induces Cardiac Fibrosis and Proliferation of Vascular Smooth Muscle Cells in Heart-Specific Transgenic Mice
2005
Site-Selective Regulation of Platelet-Derived Growth Factor β Receptor Tyrosine Phosphorylation by T-Cell Protein Tyrosine Phosphatase
2004
Roles of PDGF in animal development
2003
Changes in proteoglycan composition during development of rat skin. The occurrence in fetal skin of a chondroitin sulfate proteoglycan with high turnover rate.
1986
COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis
2010
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Biosynthesis of heparin. Concerted action of late polymer-modification reactions.
1980
Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement.
1992
Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin.
1980
Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation
2009
Investigating Cellular Metabolism of Synthetic Azidosugars with the Staudinger Ligation
2002 StandoutNobel
Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization
2010
Proteins of the Bacillus stearothermophilus ribosome. The amino acid sequences of proteins S5 and L30.
1984
Cytokine detection by antibody-based proximity ligation
2004
Controversial glycosaminoglycan conformations
1985 StandoutNatureNobel
Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors.
1996
Predominant contribution of surface approximation to the mechanism of heparin acceleration of the antithrombin-thrombin reaction. Elucidation from salt concentration effects.
1991
Cancer Genome Landscapes
2013 StandoutScience
Heparin and ionic strength-dependent conversion of antithrombin III from an inhibitor to a substrate of alpha-thrombin.
1985
Functional Upregulation of the Vascular Endothelial Growth Factor Receptor KDR by Hypoxia
1996
Effects of platelet-derived growth factor and transforming growth factor-beta 1 on the synthesis of a large versican-like chondroitin sulfate proteoglycan by arterial smooth muscle cells.
1991
Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.
2002
Assignment of intrachain disulfide bonds in platelet-derived growth factor B-chain
1993
Ligand-induced polyubiquitination of the platelet-derived growth factor beta-receptor.
1992
Abnormal gastrointestinal development in PDGF-A and PDGFR-α deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis
2000
The Effect of Platelet-Derived Growth Factor Ligands in Rat Cardiac Allograft Vasculopathy and Fibrosis
2006
Expression of platelet-derived growth factor and its receptors in neuroendocrine tumors of the digestive system.
1992
Expression of platelet-derived growth factor and its receptors in proliferative disorders of fibroblastic origin.
1992
Expression of PDGF A-chain and beta-receptor genes during rat myoblast differentiation.
1990
Agrin, Aquaporin-4, and Astrocyte Polarity as an Important Feature of the Blood-Brain Barrier
2009
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Structural and functional studies on platelet-derived growth factor.
1992
Enzyme-catalyzed synthesis of carbohydrates
1989
Identification of three amino acids in the platelet-derived growth factor (PDGF) B-chain that are important for binding to the PDGF beta-receptor
1991
Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle
1999
Anticoagulant activity of heparin: Separation of high‐activity and low‐activity heparin species by affinity chromatography on immobilized antithrombin
1976
Early myotome specification regulates PDGFA expression and axial skeleton development
2000
Structure of the antithrombin-binding site in heparin.
1979
Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases.
1993
Quantitative characterization of the thrombin-heparin interaction. Discrimination between specific and nonspecific binding models.
1991
PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly.
1992
Ligand-induced ubiquitination of the platelet-derived growth factor beta-receptor plays a negative regulatory role in its mitogenic signaling.
1993
Anticoagulant activities of heparin oligosaccharides and their neutralization by platelet factor 4
1984
Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor.
1991
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
2003
Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis
2004
Mono- and bidimensional 500 MHz 1H-NMR spectra of a synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: Evidence for conformational peculiarity of the sulfated iduronate residue
1985
Loss of T-Cell Protein Tyrosine Phosphatase Induces Recycling of the Platelet-derived Growth Factor (PDGF) β-Receptor but Not the PDGF α-Receptor
2006
PDGF alpha- and beta-receptors activate unique and common signal transduction pathways.
1992
Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice
2001
Mitogenic signals for platelet-derived growth factor isoforms in liver fat-storing cells
1991
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Evaluation of critical groups required for the binding of heparin to antithrombin.
1984
Periodate oxidation and the shapes of glycosaminoglycuronans in solution
1978
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Works of Gudrun Bäckström being referenced
Role of Immunoglobulin-like Domains 2–4 of the Platelet-derived Growth Factor α-Receptor in Ligand-Receptor Complex Assembly
1998
Expression of Three Recombinant Homodimeric Isoforms of PDGF inSaccharomyces cerevisiae: Evidence for Difference in Receptor Binding and Functional Activities
1989
Involvement of Loop 2 of Platelet-Derived Growth Faetor-AA and-BB in Receptor Binding
1995
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall
2003
PDGF-C is a new protease-activated ligand for the PDGF α-receptor
2000
Oral Imatinib Mesylate (STI571/Gleevec) Improves the Efficacy of Local Intravascular Vascular Endothelial Growth Factor-C Gene Transfer in Reducing Neointimal Growth in Hypercholesterolemic Rabbits
2004
Biosynthesis of L-iduronic acid in heparin: Epimerization of D-glucuronic acid on the polymer level
1972
Biosynthesis of Heparin
1973
Structure and Function of Basement Membrane Proteoglycans
2007
Further characterization of the antithrombin-binding sequence in heparin
1982 Standout
Biosynthesis of Heparin
1974
Biosynthesis of heparin. Loss of C-5 hydrogen during conversion of d-glucuronic to l-iduronic acid residues
1976
Localization of platelet-derived growth factor (PDGF) in CHO cells transfected with PDGF A- or B-chain cDNA: Retention of PDGF-BB in the endoplasmic reticulum and Golgi complex
1990
The molecular size of the antithrombin‐binding sequence in heparin
1980