Citation Impact
Citing Papers
Loss of Integrin α1β1 Ameliorates Kras-Induced Lung Cancer
2008
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
2008 Standout
Sequential Activation of the MEK-Extracellular Signal-Regulated Kinase and MKK3/6-p38 Mitogen-Activated Protein Kinase Pathways Mediates Oncogenic ras -Induced Premature Senescence
2002
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
2009 Standout
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer.
2001
RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells
2010
Prognostic significance of phosphorylated P38 mitogen‐activated protein kinase and HER‐2 expression in lymph node‐positive breast carcinoma
2004
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians
1998
Idiopathic pulmonary fibrosis
2017 Standout
The p38 MAPK stress pathway as a tumor suppressor or more?
2008
K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
2008 Standout
Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
2001
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
1999 Standout
Mitogen-activated protein kinase p38 and MK2, MK3 and MK5: Ménage à trois or ménage à quatre?
2010
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
Chemopotentiation by PARP inhibitors in cancer therapy
2005
PARP inhibitor combination therapy
2016
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
The pathways to tumor suppression via route p38
2007
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
Wound repair and regeneration
2008 StandoutNature
The resurgence of platinum-based cancer chemotherapy
2007 Standout
Transcriptional Regulation of Heme Oxygenase-1 Gene Expression by MAP Kinases of the JNK and p38 Pathways in Primary Cultures of Rat Hepatocytes
2003
Cellular Senescence in Cancer and Aging
2007 Standout
Activation of p38 Has Opposing Effects on the Proliferation and Migration of Endothelial Cells
2005
Poly(ADP-ribose) Polymerase-1-mediated Cell Death in Astrocytes Requires NAD+ Depletion and Mitochondrial Permeability Transition
2004
Inactivation of the Poly(ADP-ribose) Polymerase Gene Affects Oxygen Radical and Nitric Oxide Toxicity in Islet Cells
1995
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Cancer genes and the pathways they control
2004 Standout
VEGF receptor signalling ? in control of vascular function
2006 Standout
Opposing Roles of Mitogenic and Stress Signaling Pathways in the Induction of Cancer Dormancy
2006
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Upstream and downstream of mTOR
2004 Standout
Cell-free nucleic acids as biomarkers in cancer patients
2011 Standout
Regulation of cancer cell metabolism
2011 Standout
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome
2007 StandoutNobel
Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38
2005
Targeting RAS signalling pathways in cancer therapy
2003 Standout
p38 MAP-Kinases pathway regulation, function and role in human diseases
2007
The essence of senescence: Figure 1.
2010 Standout
Understanding the Odd Science of Aging
2005 Standout
Apoptosis
2002 Standout
Antisense therapy in oncology: new hope for an old idea?
2001
P38 MAP Kinase Signaling Is Required for the Conversion of CD4+CD25− T Cells into iTreg
2008
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
High‐level expression, activation, and subcellular localization of p38‐MAP kinase in thyroid neoplasms
2006
PI3K/Akt signalling pathway and cancer
2003 Standout
p38α MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis
2007
Physiological roles of mitogen-activated-protein-kinase-activated p38-regulated/activated protein kinase
2011
Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38α in abrogating myoblast proliferation
2007
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
p38α and p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells
2007
Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
1995 StandoutNobel
5-Fluorouracil: mechanisms of action and clinical strategies
2003 Standout
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
Idiopathic pulmonary fibrosis
2011 Standout
A Phase I trial of h-ras antisense oligonucleotide ISIS 2503 administered as a continuous intravenous infusion in patients with advanced carcinoma
2001
Pluronic® block copolymers for overcoming drug resistance in cancer
2002
The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I
1995 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
Modulation of cis-diamminedichloroplatinum(II) resistance: a review
1992
Vitamin D controls T cell antigen receptor signaling and activation of human T cells
2010
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Role of the Glutathione Metabolic Pathway in Lung Cancer Treatment and Prognosis: A Review
2006
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Tumour stem cells and drug resistance
2005 Standout
p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells.
2003
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
New Mechanistic and Functional Insights into DNA Topoisomerases
2013
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
2001 Standout
Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.
2002
Insights into Mechanisms of Cisplatin Resistance and Potential for Its Clinical Reversal
1996
Repeated observation of breast tumor subtypes in independent gene expression data sets
2003 Standout
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
6-Aminonicotinamide sensitizes human tumor cell lines to cisplatin.
1998
Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy
2001 Standout
68Ga-labeled oligonucleotides for in vivo imaging with PET.
2004
Antisense treatment directed against mutated Ki-ras in human colorectal adenocarcinoma
2001
Artificial Molecular Machines
2015 Standout
trans-Dominant Inhibition of Poly(ADP-Ribosyl)ation Sensitizes Cells against γ-Irradiation and N-Methyl-N′-Nitro-N-Nitrosoguanidine but Does Not Limit DNA Replication of a Polyomavirus Replicon
1995
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Direct Cellular Responses to Platinum-Induced DNA Damage
2007
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Mechanism of Action of Sulforaphane: Inhibition of p38 Mitogen-Activated Protein Kinase Isoforms Contributing to the Induction of Antioxidant Response Element–Mediated Heme Oxygenase-1 in Human Hepatoma HepG2 Cells
2006
v-Src Generates a p53-Independent Apoptotic Signal
2000
Works of Guan Chen being referenced
Enhancement of cisplatin (DDP) antitumor activity by 3-aminobenzamide in rat ovarian tumors sensitive and resistant to DDP in vivo
1990
Multiple effects of 3-aminobenzamide on DNA damage induced by cisplatin (DDP) in DDP-sensitive and -resistant rat ovarian tumor cell lines
1992
Estrogen Receptor Inhibits c-Jun-dependent Stress-induced Cell Death by Binding and Modifying c-Jun Activity in Human Breast Cancer Cells
2004
Reversal of acquired cisplatin resistance by nicotinamide in vitro and in vivo
1993
Transforming growth factor-β in in vivo resistance
1996
Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells
1994
p38 MAPK Activation Selectively Induces Cell Death in K-ras-mutated Human Colon Cancer Cells through Regulation of Vitamin D Receptor
2004
The p38 Pathway Provides Negative Feedback for Ras Proliferative Signaling
2000
Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells
1995
Increased poly(ADP-ribosyl)ation in intact cells by cisplatin treatment
1993
Protection against cyclophosphamide-induced alopecia and inhibition of mammary tumor growth by topical 1,25-dihydroxyvitamin D3 in mice
1998
Antisense Oligonucleotides Demonstrate a Dominant Role of c-Ki-RAS Proteins in Regulating the Proliferation of Diploid Human Fibroblasts
1996
p38 Isoforms Have Opposite Effects on AP-1-dependent Transcription through Regulation of c-Jun
2003
Oncogenic transformation potentiates apoptosis, S-phase arrest and stress-kinase activation by etoposide
1997
Essential Role of p38γ in K-Ras Transformation Independent of Phosphorylation
2005
Phosphorylation and Stabilization of Topoisomerase IIα Protein by p38γ Mitogen-activated Protein Kinase Sensitize Breast Cancer Cells to Its Poisons
2011
Potentiation of the antitumor activity of cisplatin in mice by 3-aminobenzamide and nicotinamide
1988
Increased poly(ADP-ribose) formation in cisplatin-resistant rat ovarian tumor cells.
1994
p38γ Mitogen-Activated Protein Kinase Integrates Signaling Crosstalk between Ras and Estrogen Receptor to Increase Breast Cancer Invasion
2006
The p38 and JNK Pathways Cooperate to trans-Activate Vitamin D Receptor via c-Jun/AP-1 and Sensitize Human Breast Cancer Cells to Vitamin D3-induced Growth Inhibition
2002