Citation Impact
Citing Papers
The role of JAK/STAT signaling pathway and its inhibitors in diseases
2020
Structure–activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues
2007
Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei
2001
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Synthesis of benzosultams via an intramolecular sp2C–H bond amination reaction of o-arylbenzenesulfonamides under metal-free conditions
2013
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
A Review on the Dietary Flavonoid Kaempferol
2011 Standout
The JAK/STAT signaling pathway: from bench to clinic
2021 Standout
Crohn's disease
2016 Standout
JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects
2017
Drug repurposing: progress, challenges and recommendations
2018 Standout
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
JAK–STAT pathway targeting for the treatment of inflammatory bowel disease
2020
Optimizing Delays in the MBOB, Broadband HMBC, and Broadband XLOC NMR Pulse Sequences
2002 StandoutNobel
Ulcerative colitis
2020 Standout
Polymorphic Cytochrome P450 2D6: Humanized Mouse Model and Endogenous Substrates
2004
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Emerging applications of metabolomics in drug discovery and precision medicine
2016
The ReaxFF reactive force-field: development, applications and future directions
2016 Standout
Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle
2015
3d Transition Metals for C–H Activation
2018 Standout
Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis
2017
Structural Elucidation and Quantification of Phenolic Conjugates Present in Human Urine after Tea Intake
2012
The chemistry of recently isolated naturally occurring quinazolinone alkaloids
2006 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
MetaboAnalystR: an R package for flexible and reproducible analysis of metabolomics data
2018 Standout
Current Status of the Research and Development of Diacylglycerol O-Acyltransferase 1 (DGAT1) Inhibitors
2013
Heterocycles in drugs and drug discovery
2012
Acetate retention and metabolism in the hyporheic zone of a mountain stream
1999
Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer
2011
Accessing Drug Metabolites via Transition‐Metal Catalyzed C−H Oxidation: The Liver as Synthetic Inspiration
2016
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Extended-Connectivity Fingerprints
2010 Standout
Metabolism-guided drug design
2012
Hyporheic flow and transport processes: Mechanisms, models, and biogeochemical implications
2014 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Covalent O–H Bonds as Electron Traps in Proton-Rich Rutile TiO2 Nanoparticles
2014 StandoutNobel
Jaguar: A high‐performance quantum chemistry software program with strengths in life and materials sciences
2013
JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines
2015
Janus kinase inhibitors: A therapeutic strategy for cancer and autoimmune diseases
2020
Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box
2015 Standout
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective
2018 Standout
Extending the application of biocatalysis to meet the challenges of drug development
2018
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Direct Renin Inhibitors as a New Therapy for Hypertension
2010
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Pharmacophoric Fingerprint Method (TOPP) for 3D-QSAR Modeling: Application to CYP2D6 Metabolic Stability
2006
The merger of transition metal and photocatalysis
2017 Standout
Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far
2013 Standout
OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins
2015 Standout
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
2011
Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
2008 Standout
Works of Gregory S. Walker being referenced
Biosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic Stability
2016
Validation of Isolated Metabolites from Drug Metabolism Studies as Analytical Standards by Quantitative NMR
2010
Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
2010
Metabolic Aromatization of N-Alkyl-1,2,3,4-Tetrahydroquinoline Substructures to Quinolinium by Human Liver Microsomes and Horseradish Peroxidase
2006
Biosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism Studies
2014
The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
2014
Bioactivation of Lamotrigine in Vivo in Rat and in Vitro in Human Liver Microsomes, Hepatocytes, and Epidermal Keratinocytes: Characterization of Thioether Conjugates by Liquid Chromatography/Mass Spectrometry and High Field Nuclear Magnetic Resonance Spectroscopy
2009
Lead Diversification at the Nanomole Scale Using Liver Microsomes and Quantitative Nuclear Magnetic Resonance Spectroscopy: Application to Phosphodiesterase 2 Inhibitors
2018
Increased HMBC Sensitivity for Correlating Poorly Resolved Proton Multiplets to Carbon-13 Using Selective or Semi-selective Pulses
1996
Relative Values of Oxygen, Nitrate, and Sulfate to Terminal Microbial Processes in the Sediments of Lake Superior
1989
Inhibition of Cytochrome P450 2D6: Structure−Activity Studies Using a Series of Quinidine and Quinine Analogues
2003
Oxidative Metabolism of a Quinoxaline Derivative by Xanthine Oxidase in Rodent Plasma
2011
Determination of Degradation Pathways and Kinetics of Acyl Glucuronides by NMR Spectroscopy
2007
In VitroMetabolism and Covalent Binding of Enol-Carboxamide Derivatives and Anti-Inflammatory Agents Sudoxicam and Meloxicam: Insights into the Hepatotoxicity of Sudoxicam
2008
Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1
2011
Late-Stage Microsomal Oxidation Reduces Drug–Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189
2018
Long-range two-dimensional1H-15N heteronuclear shift correlation at natural abundance using GHNMQC. A study of the reverse transcriptase inhibitor delavirdine
1997
A Rational Chemical Intervention Strategy To Circumvent Bioactivation Liabilities Associated with a Nonpeptidyl Thrombopoietin Receptor Agonist Containing a 2-Amino-4-arylthiazole Motif
2007