Standout Papers
Citation Impact
Citing Papers
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Synthesis of 3-substituted-4-hydroxyquinoline N-oxides from the Baylis–Hillman adducts of o-nitrobenzaldehydes
2003
Titanium(IV) chloride and oxy-compounds promoted Baylis–Hillman reaction
2001
Recent advances in the catalytic asymmetric synthesis of β-amino acids
2010 StandoutNobel
Asymmetric Counteranion‐Directed Catalysis: Concept, Definition, and Applications
2012 StandoutNobel
Asymmetric Counteranion‐Directed Catalysis for the Epoxidation of Enals
2007 StandoutNobel
Nitrile biotransformations for the synthesis of enantiomerically enriched Baylis–Hillman adducts
2002
A New Approach to Osmium-Catalyzed Asymmetric Dihydroxylation and Aminohydroxylation of Olefins
2002 StandoutNobel
Highly Enantioselective Regiodivergent and Catalytic Parallel Kinetic Resolution
2001 StandoutNobel
Catalytic, Asymmetric Aza‐Baylis–Hillman Reaction of N‐Sulfonated Imines with Activated Olefins by Quinidine‐Derived Chiral Amines
2005
Self-assisted tandem Michael-aldol reactions of α,β-unsaturated ketones with aldehydes
2001
N‐Phosphinyl Phosphoramide—A Chiral Brønsted Acid Motif for the Direct Asymmetric N,O‐Acetalization of Aldehydes
2010 StandoutNobel
Catalytic Asymmetric Acylcyanation of Imines
2006 StandoutNobel
Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity
2009 Standout
Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds
2011 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Direct Catalytic Asymmetric Three‐Component Kabachnik–Fields Reaction
2008 StandoutNobel
Asymmetric spiroacetalization catalysed by confined Brønsted acids
2012 StandoutNatureNobel
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
High Substrate/Catalyst Organocatalysis by a Chiral Brønsted Acid for an Enantioselective Aza‐Ene‐Type Reaction
2006
Development of Dirhodium(II)-Catalyzed Generation and Enantioselective 1,3-Dipolar Cycloaddition of Carbonyl Ylides
2001
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Ruthenium catalysed cross metathesis with fluorinated olefins
2001
The Baylis–Hillman reaction in supercritical carbon dioxide: enhanced reaction rates, unprecedented ether formation, and a novel phase-dependent 3-component coupling
2002
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
The advent and development of organocatalysis
2008 StandoutNature
Improved Cyclopropanation Activity of Histidine‐Ligated Cytochrome P450 Enables the Enantioselective Formal Synthesis of Levomilnacipran
2014 StandoutNobel
The Organic Approach to Asymmetric Catalysis
2006 StandoutScienceNobel
Pd‐Catalyzed Stereoselective Oxidation of Methyl Groups by Inexpensive Oxidants under Mild Conditions: A Dual Role for Carboxylic Anhydrides in Catalytic CH Bond Oxidation
2005
High symmetry dirhodium(II) paddlewheel complexes as chiral catalysts
2007
β2‐amino acids—syntheses, occurrence in natural products, and components of β‐peptides1,2
2004
Lewis Base Catalysis in Organic Synthesis
2008
Simple preparation of β-hydroxy-α-thiomethyl carbonyl compounds via stereoselective conjugate addition of thiol to Baylis–Hillman adducts
2002
Carbenoid Reactions in Rhodium(II)‐Catalyzed Decomposition of Iodonium Ylides
1995
Intramolecular Baylis−Hillman and Morita Reactions Using Unsaturated Thiol Ester Substrates Containing Enolizable Aldehydes
2002
The Most Simple and Convenient Synthesis of the Baylis-Hillman Adducts of Cycloalkenones:Use of DMAP in Aqueous THF
2002
2-Formylimidazole as Substrate in Baylis-Hillman Reactions: Synthesis of a β-Substituted Acrylate
1997
Preparation and Catalytic Properties of Immobilized Chiral Dirhodium(II) Carboxamidates
2002
Lewis acid-promoted carbonyl addition of lithium (α-carbalkoxyvinyl)cuprates to aldehydes provides a novel asymmetric synthesis of β,β-disubstituted α-(hydroxyalkyl)acrylates
1998
Ultrasound in Baylis–Hillman reactions with aliphatic and aromatic aldehydes: scope and limitations
2002
Effect of carbenoid structure on the reactions of rhodium-stabilized carbenoids with cycloheptatriene
2000
On the Baylis–Hillman reaction of acrylate, acrylonitrile, and acrolein with some non-enolizable α-dicarbonyl compounds: synthesis of phytotoxic bipolaroxin models
1995
Asymmetric synthesis of substituted chromanones via C–H insertion reactions of α-diazoketones catalysed by homochiral rhodium(II ) carboxylates
1992
Synthesis of unsaturated β-amino acid derivatives from carbamates of the Baylis–Hillman products
2002
Enantioselective Synthesis of d -threo-Methylphenidate
1999
Amine and Titanium (IV) Chloride, Boron (III) Chloride or Zirconium (IV) Chloride-Promoted Baylis-Hillman Reactions
2001
Steric balance within chiral dirhodium(II) carboxamidate catalysts enhances stereoselectivity
2003
Resolution of Diols via Catalytic Asymmetric Acetalization
2015 StandoutNobel
Novel application of phosphonium salts as co-catalysts for the Baylis–Hillman reaction
2004
Indolizine studies. Part 2. Synthesis and NMR spectroscopic analysis of 2-substituted indolizines
1993
One-pot aza-Baylis–Hillman reactions of arylaldehydes and diphenylphosphinamide with methyl vinyl ketone in the presence of TiCl4, PPh3, and Et3N
2002
Activation of H2O2 by Chiral Confined Brønsted Acids: A Highly Enantioselective Catalytic Sulfoxidation
2012 StandoutNobel
Sulfide–BF3·OEt2 mediated Baylis–Hillman reactions
2002
Rhodium(II)-catalyzed nitrene transfer with phenyliodonium ylides
1998
On the metal-catalysed epoxidation of electron-deficient olefins
1991
Synthesis of 3-Ethoxycarbonyl-4-hydroxyquinoline N-Oxides from the Baylis−Hillman Adducts of o-Nitrobenzaldehydes
2000
β-Isocupreidine–hexafluoroisopropyl acrylate method for asymmetric Baylis–Hillman reactions
2005
Terminal Hydroxyalkyl Acrylates as Substrates for Baylis-Hillman Reaction
1990
First examples of metal and ligand accelerated catalysis of the Baylis–Hillman reaction
1996
First enantioselective synthesis of mikanecic acid via Diels-Alder cycloaddition mediated construction of chiral vinylic quaternary center
1994
Hydroxyalkylation of Diethylvinylphosphonate in the Presence of DABCO
1990
A new rhodium(II) phosphate catalyst for diazocarbonyl reactions including asymmetric synthesis
1992
Chiral Catalyst Controlled Diastereoselection and Regioselection in Intramolecular Carbon−Hydrogen Insertion Reactions of Diazoacetates
1996
Stereo‐ and Regiocontrol in the Formation of Lactams by Rhodium‐Carbenoid C−H Insertion of α‐Diazoacetamides
2004
Chiral Amine-Catalyzed Asymmetric Baylis−Hillman Reaction: A Reliable Route to Highly Enantiomerically Enriched (α-Methylene-β-hydroxy)esters
1999
Chiral acrylates as substrates in baylis-hillman reaction
1990
2,6-Diphenyl-4H-chalcogenopyran-4-ones and 2,6-diphenyl-4H-chalcogenopyran-4-thiones: a new catalyst for the Baylis-Hillman reaction
1999
Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
2011 Standout
The first enantioselective synthesis of isoflavonoids: (R)- and (S)-isoflavans
1995
Nucleophilic Chiral Amines as Catalysts in Asymmetric Synthesis
2003
A General Model for Selectivity in Olefin Cross Metathesis
2003 StandoutNobel
Enantiomer differentiation in intramolecular carbon?hydrogen insertion reactions of racemic secondary alkyl diazoacetates catalyzed by chiral dirhodium(ii) carboxamidates
1995
Catalytic Asymmetric C−H Activation of Alkanes and Tetrahydrofuran
2000
Synthesis of fluoromethylated materials in ionic liquids
2002
Recent progress in asymmetric intermolecular CH activation by rhodium carbenoid intermediates
2001
Reexamination of the traditional Baylis–Hillman reaction
2003
New Catalysts and Conditions for a CH Insertion Reaction Identified by High Throughput Catalyst Screening
1996
Lewis Base Effects in the Baylis−Hillman Reaction of Imines with Methyl Vinyl Ketone
2002
Asymmetric synthesis of β-monosubstituted and β,β-disubstituted N-(p-toluenesulfinyl)-α-(aminoalkyl)acrylates via anionic additions of (α-carbalkoxyvinyl)cuprates to thiooxime S-oxides
1999
Metal- and Ligand-Accelerated Catalysis of the Baylis−Hillman Reaction
1998
Synthetic applications of the baylis-hillman reaction: Simple synthesis of [2E]-2-butyloct-2-enal and [2E]-2-tridecylheptadec-2-enal
1996
Catalytic enantioselective Baylis-Hillman reactions. Correlation between pressure and enantiomeric excess
1997
TiCl4-Promoted Baylis−Hillman Reactions of Substituted 5-Isoxazolecarboxaldehydes with Cycloalkenones1
2002
Mechanism of α‐substitution reactions of acrylic derivatives
1990
New Strategic Reactions for Organic Synthesis: Catalytic Asymmetric C—H Activation α to Nitrogen as a Surrogate for the Mannich Reaction.
2003
C-H Bond Functionalization in Complex Organic Synthesis
2006 StandoutScience
Applications of Baylis–Hillman coupling products: a remarkable reversal of stereochemistry from esters to nitriles: a simple synthesis of (2E)-2-methylalk-2-en-1-ols and (2Z)-2-methylalk-2-enenitriles
1992
Montmorillonite clay-catalyzed stereoselective syntheses of aryl-substituted (E)- and (Z)-allyl iodides and bromides
2001
The Aqueous Trimethylamine Mediated Baylis-Hillman Reaction
2000
Allene synthesis by an asymmetric Baylis–Hillman style reaction on vinylphosphine oxides
2001
The chalcogeno-Baylis–Hillman reaction: the first examples catalysed by chalcogenides in the presence of Lewis acids
1998
DMAP-catalyzed hydroxymethylation of 2-cyclohexenones in aqueous medium through Baylis-Hillman reaction
1998
Novel Asymmetric C−C Bond Formation Process Promoted by Et2AlCl and Its Application to the Stereoselective Synthesis of Unusual β-Branched Baylis−Hillman Adducts
1999
Asymmetric rhodium carbenoid insertion into the SiH bond
1996
Phosphine mediated synthesis of 2-methylidene-3-amino esters and ketones
1989
Modern Organic Synthesis with α-Diazocarbonyl Compounds
2015
An Asymmetric Synthesis of Aza Analogues of the Tricyclic Skeleton of Daphnane and the ABC Ring System of Phorbol
2002
Observations of Rhodium‐Containing Reaction Intermediates using HPLC with ICP‐MS and ESI‐MS Detection
2006
Chiral catalysts for enantioselective intermolecular cyclopropanation reactions with methyl phenyldiazoacetate. Origin of the solvent effect in reactions catalyzed by homochiral dirhodium(II) prolinates
1996
Piperonal as electrophile in the Baylis-Hillman reaction. A synthesis of hydroxy-β-piperonyl-γ-butyrolactone derivative
1998
Recent Advances in Asymmetric Catalytic Metal Carbene Transformations
1998 Standout
Diastereoselective Baylis–Hillman type reactions of chiral non-racemic N-sulfinimines with cyclopent-2-en-1-one
2002
Deracemization of α-Aryl Hydrocoumarins via Catalytic Asymmetric Protonation of Ketene Dithioacetals
2012 StandoutNobel
An efficient and general route to reduced polypropionates via Zr-catalyzed asymmetric C—C bond formation
2004 StandoutNobel
Effect of branching in alkylgroups of tertiary amines on their performance as catalysts in the high pressure promoted Baylis-Hillman reaction
1996
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
Asymmetric synthesis of 1,4-cycloheptadienes and bicyclo[3.2.1]octa-2,6-dienes by rhodium(II) N-(p-(tert-butyl)phenylsulfonyl)prolinate catalyzed reactions between vinyldiazomethanes and dienes
1994
Stereoselective Synthesis of Medium-Sized Cyclic Compounds by Means of Tandem Reactions of a Cyclic Oxosulfonium Ylide with Acetates of Baylis−Hillman Adducts
2001
Chiral catalysts for enantioselective carbenoid cyclopropanation reactions
1991
1,2‐Stereoinduction in Radical Reactions: Stereoselective Synthesis of 2‐Alkyl‐3‐hydroxybutanoates
1991
The synthesis and properties of a series of novel side-chain liquid crystal polymers based on the Baylis-Hillman reaction
1994
Highly Enantioselective Aza‐Baylis–Hillman Reactions Catalyzed by Chiral Thiourea Derivatives
2005
Reactivity and Selectivity of Ortho-Metalated Rhodium(II) Complexes in C−H Insertion Reactions of α-Diazo Compounds
1998
Syn‐Stereocontrolled dihydroxylation of Baylis‐Hillman adducts
1995
New Strategies for the Development of an Asymmetric Version of the Baylis–Hillman Reaction
2000
Catalytic Asymmetric [4+2]-Cycloaddition of Dienes with Aldehydes
2017 StandoutNobel
Lewis base and l-proline co-catalyzed Baylis–Hillman reaction of arylaldehydes with methyl vinyl ketone
2002
Parallel synthesis techniques in the identification of new chiral dirhodium(II) carboxylates for asymmetric carbenoid insertion reactions
1998
The crystallographic structure of 4-hydroxy-3-methylene-4-(p-nitrophenyl)butan-2-one
1999
Enantiocontrol in the Generation and Diastereoselective Reactions of Catalytically Generated Oxonium and Iodonium Ylides. Metal-Stabilized Ylides as Reaction Intermediates
1998
Asymmetric dipolar cycloaddition reactions of diazocompounds mediated by a binaphtholphosphate rhodium catalyst
1992
Stereoselective intramolecular carbon–hydrogen insertion reactions of metal carbenes
1998
Rhodium(II)-catalyzed aziridinations and CH insertions with [N-(p-nitrobenzenesulfonyl)imino]phenyliodinane
1996
A novel tetrahydrofuran derivative via a tertiary ketol-type rearrangement
1993
Hydroxyl ionic liquid (HIL)-immobilized quinuclidine for Baylis–Hillman catalysis: synergistic effect of ionic liquids as organocatalyst supports
2006
Biocatalytic Approach to Optically Active Baylis-Hillman Reaction Products
1994
Enantiocontrol and regiocontrol in lactam syntheses by intramolecular carbon-hydrogen insertion reactions of diazoacetamides catalyzed by chiral rhodium(II) carboxamides
1992
Rhodium(II)‐Catalyzed CH Insertions with {[(4‐Nitrophenyl)sulfonyl]imino}phenyl‐λ3‐iodane
1997
New Type of Photochemical Carbon Skeletal Rearrangement: Transformation of α,β-Unsaturated Carbonyl to 1,4-Dicarbonyl Compounds
1998
DABCO-Catalysed Dimerisation of Some α,β-Unsaturated Esters
1990
Applications of Baylis–Hillman chemistry: one-pot convenient synthesis of functionalized (1H)-quinol-2-ones and quinolines
2002
One-pot facile conversion of the acetates of Baylis–Hillman adducts into substituted fused pyrimidones in aqueous media
2002
Catalytic and stereoselective iodination of prochiral C–H bonds
2005
Enantiocontrolled Macrocycle Formation by Catalytic Intramolecular Cyclopropanation
2000
Selective Formation of Six-Membered Cyclic Sulfones and Sulfonates by C−H Insertion
2006
Development and Applications of Disulfonimides in Enantioselective Organocatalysis
2015 StandoutNobel
Lithium perchlorate-accelerated Baylis-Hillman reactions
1999
Synthesis of ethyl 3-cyano-2-methylcinnamates and 3-cyano-2-methylcinnamonitriles from the Baylis–Hillman acetates
2001
Asymmetric induction in the Baylis-Hillman reaction
1991
Baylis–Hillman chemistry: a novel synthesis of functionalized 1,4-pentadienes
2001
The first enantioselective synthesis of the chemotactic factor sirenin by an intramolecular [2 + 1] cyclization using a new chiral catalyst
1995 Nobel
Z/ESTEREOSELECTIVE SYNTHESIS OF β-BROMO BAYLIS-HILLMAN KETONES VIA A ONE-POT THREE-COMPONENT X–C/C–C FORMATION REACTION
2002
Acceleration in water of the Baylis-Hillman reaction
1994
Chemoselectivity and stereoselectivity of cyclisation of α-diazocarbonyls leading to oxygen and sulfur heterocycles catalysed by chiral rhodium and copper catalysts
1995
The chalcogeno-Baylis-Hillman reaction: a new preparation of allylic alcohols from aldehydes and electron-deficient alkenes
1998
Diethyl Ketomalonate: A Fast Reacting Substrate for Baylis-Hillman Reaction
1989
Asymmetric Cyclopropanations by Rhodium(II) N-(Arylsulfonyl)prolinate Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Alkenes. Practical Enantioselective Synthesis of the Four Stereoisomers of 2-Phenylcyclopropan-1-amino Acid
1996
Facile Diastereoselective Synthesis of 2,6‐Dialkyl‐5‐methylene‐1,3‐dioxan‐4‐ones via α‐Activated Vinyl Esters
1990
Amendment in Titanium(IV) Chloride and Chalcogenide-Promoted Baylis–Hillman Reaction of Aldehydes with α,β-Unsaturated Ketones
2000
A remarkable rate acceleration of the Baylis–Hillman reaction
2001
Nucleophilic addition of triethyl phosphite to acetates of the baylis-hillman adducts: Stereoselective synthesis of (E)- and (Z)-allylphosphonates
1996
Application of Intramolecular Carbenoid Reactions in Organic Synthesis
1992
A Dirhodium(II)−Carbenoid Route to (−)- and (+)-Geissman−Waiss Lactone: Synthesis of (1R,7R,8R)-(−)-Turneforcidine
2001
A Novel and Facile Synthesis of Functionalized [4.4.3] and [4.4.4]Propellano-bislactones Using Acetates of the Baylis−Hillman Adducts
2001
Dimerization of (e)-2-benzenesulfonyl-1,3-alkadienes the benzenesulfonyl group exerts acyclic stereocontrol
1990
Dimethyl sulfide–boron trihalide-mediated reactions of α,β-unsaturated ketones with aldehydes: one-pot synthesis of Baylis–Hillman adducts and α-halomethyl enones
2001
Stereoselective Cyclopropanation Reactions
2003 Standout
Asymmetric Baylis-Hillman Reactions of Novel Bornyl Acrylate Esters
1999
Application of Baylis–Hillman methodology in a novel synthesis of quinoline derivatives
1998
A short stereoselective synthesis of (+)- and (−)-2-oxabicyclo[3.3.0]oct-6-en-3-one by intramolecular carbon–hydrogen insertion catalyzed by chiral dirhodium(II) carboxamidates
2003
A Novel Route to Substituted Trienes and Tetraenes
1993
Chalcogenide-TiCl4-mediated reactions of S-ethyl thioacrylate with aldehydes
2000
Tributylphosphine-catalyzed Stetter reaction of N,N-dimethylacrylamide: synthesis of N,N-dimethyl-3-aroylpropionamides
2002
The Baylis–Hillman chemistry in aqueous media: a convenient synthesis of 2-methylenealkanoates and alkanenitriles
2001
RuCl2(PPh3)3Catalyzed Isomerization of the Baylis-Hillman Adducts
1999
Stereochemical study on the palladium(O)-catalyzed carbonylation of 3-(methoxycarbonyloxy)-2-methylenealkanoates and analogues
1992
Chain extension of acyclic sugar derivatives via the Baylis–Hillman reaction
2002
Catalysts with Mixed Ligands on Immobilized Supports. Electronic and Steric Advantages
2003
Asymmetric hetero-Diels–Alder reaction catalyzed by dirhodium(II) carboxamidates
2004
Synthesis of chiral bicyclic azetidine derivatives
2002
Baylis-Hillman reaction of N-trityl aziridine-2-(S)-carboxaldehyde
1999
TANDEM CONSTRUCTION OF CARBON–CARBON AND CARBON–OXYGEN BONDS IN THE BAYLIS-HILLMAN CHEMISTRY: SYNTHESIS OF FUNCTIONALIZEDdl-BIS-ALLYL ETHERS
2002
Titanium Isopropoxide as Efficient Catalyst for the Aza-Baylis−Hillman Reaction. Selective Formation of α-Methylene-β-amino Acid Derivatives
2002
The Baylis–Hillman reaction under high pressure induced by water-freezing
2002
Dirhodium(II) tetra(triphenylacetate): A highly efficient catalyst for the site-selective intramolecular C-H insertion reactions of α-Diazo β-Keto Esters
1992
The DABCO-catalysed Baylis–Hillman reactions in the chloroaluminate room temperature ionic liquids: rate promoting and recyclable media
2003
Metal‐catalyzed carbenoid reactions with iodonium and sulfonium ylides
1998
Lewis‐Base‐Katalyse in der organischen Synthese
2008
A novel C–C bond formation by Baylis–Hillman type reaction mediated by SmI2: an effective approach to α-hydroxyalkylacrylamide synthesis
2000
The osmium-catalyzed aminohydroxylation of Baylis-Hillman olefins
1999 StandoutNobel
Asymmetric syntheses with catalytic enantioselective metal carbene transformations
1994
Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
Stereoselective epoxidation of hydroxyenones. The synthesis of the sidechain of clerocidin
1990
Preparation and Selected Reactions of t‐Butyl 2‐Methylene‐3‐oxoalkanoates
1991 Nobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
An exploration of asymmetric Baylis–Hillman reactions catalyzed by quinidine-derived chiral amines
2002
Selectivity in Reactions of Allyl Diazoacetates as a Function of Catalyst and Ring Size from γ-Lactones to Macrocyclic Lactones
2000
Perspective on Dirhodium Carboxamidates as Catalysts
2006
AN ALTERNATIVE ROUTE TO THE SYNTHESIS OF LIGNANS INTERMEDIATES
2001
Development of catalysts for the Baylis–Hillman reaction: the application of tetramethylguanidine and attempts to use a supported analogue
2001
Chiral, Cyclic Amino Aldehydes in the Baylis-Hillman Reaction – A Route to Sphingosine Analogues
1993
Economic preparation of 1,3-diphenyl-1,3-bis(diphenylphosphino)propane: a versatile chiral diphosphine ligand for enantioselective hydrogenations
2003
An improved approach to trifluoromethyl substituted Morita–Baylis–Hillman adduct: Fluorinated dehydro-β-amino acids
2001
The asymmetric Baylis-Hillman reaction as a template in organic synthesis
1997
Unexpected products from the Fp2-catalyzed reductive cyclization of nitroaromatics bearing pendant unsaturation
2003
Catalytic Carbene Insertion into C−H Bonds
2009 Standout
Small-Molecule H-Bond Donors in Asymmetric Catalysis
2007 Standout
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
Fluoride-promoted reactions of unsaturated carbonyl compounds. Dimerization by a non-Baylis–Hillman pathway
2001
Enantiocontrol in catalytic metal carbene reactions
1999
Efficient Baylis–Hillman reactions promoted by mild cooperative catalysts and their application to catalytic asymmetric synthesis
2000
Intramolecular Regioselective Insertion into Unactivated Prochiral Carbon−Hydrogen Bonds with Diazoacetates of Primary Alcohols Catalyzed by Chiral Dirhodium(II) Carboxamidates. Highly Enantioselective Total Synthesis of Natural Lignan Lactones
1996
Enhancement of enantioselectivity in intramolecular C-H insertion reactions of α-diazo β-keto esters catalyzed by chiral dirhodium(II) carboxylates
1993
Chiral Dirhodium(II) Catalysts with Orthometalated Aryl Phosphine Ligands: Synthesis and Application for Enantioselective C−H Insertion of α-Diazo Ketones
2001
Synthesis of Spiro-Fused (C5)-Isoxazolino-(C4)-pyrazolones (1-Oxa-2,7,8-triazaspiro[4,4]-2,8-dien-6-ones) via 1,3-Dipolar Cycloaddition and Cycloelimination
2002
Asymmetric Catalysis with CO2: The Direct α‐Allylation of Ketones
2016 StandoutNobel
Synthesis of Useful Intermediates from the Claisen-Rearrangement of α-Hydroxy Alkyl Acrylate Precursors
1990
The tetramethylguanidine catalyzed Baylis–Hillman reaction: Effects of co-catalysts and alcohol solvents on reaction rate
2002
Enhanced enantiocontrol in catalytic metal carbene transformations with dirhodium (II) tetrakis[methyl 2‐oxooxazolidin‐4(S)‐carboxylate], Rh2(4S‐MEOX)4
1995
Enantioselecitve intramolecular CH insertion of α-diazo [β-keto esters catalyzed by homochiral rhodium(II) carboxylates
1990
New chiral 1,3-diphosphine ligands for Rh-catalyzed enantioselective hydrogenation: a search for electronic effects
2005
Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions
2011
Highly Enantioselective Intramolecular Cyclopropanation Reactions of N-Allylic-N-methyldiazoacetamides Catalyzed by Chiral Dirhodium(II) Carboxamidates
1996
The reactions of aryl acrylates under Baylis-Hillman conditions
1996
Enantioselective Formation of Bicyclic Lactones by Rhodium‐Catalyzed Intramolecular CH‐insertion reactions
1994
New Dinuclear Catalysts Rh2(N−O)2[(C6H4)P(C6H5)2]2 with Imidate Ligands: Synthesis and Isomerization from Head-to-Tail to Head-to-Head Configuration of the Imidate Ligands
2001
Selective Formation of α-Methylene-β-amino acid Derivatives through the Aza Version of the Baylis−Hillman Reaction
2001
A novel Baylis–Hillman protocol for the synthesis of functionalized fused furans
2001
Synthesis and Diastereoselective Reactions of N,N-Dibenzylamino Aldehydes and Related Compounds
1999
Synthesis of enantiomerically enriched Baylis–Hillman alcohols from their acetates: combination of kinetic resolution during the salt formation with (DHQD)2PHAL and following asymmetric induction during hydrolysis with NaHCO3 as a water surrogate
2002
Intermolecular Cyclopropanation versus CH Insertion in RhII-Catalyzed Carbenoid Reactions
2000
Synthesis, resolution and assignment of absolute configuration of 2-(α-hydroxy)aryl acrylate esters
1992
Effect of solvent, pressure and catalyst on the E/Z-selectivity in the Baylis-Hillman reaction between crotononitrile and benzaldehyde
1993
Acceleration of the Baylis–Hillman Reaction in the Presence of Ionic Liquids
2003
The ‘Baylis - Hillman Reaction’ mechanism and applications revisited
1992
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Synthesis, Structure, and Activity of Enhanced Initiators for Olefin Metathesis
2003 StandoutNobel
A facile preparation of α-hydrazino-α,β-unsaturated ketones via aza-Baylis-Hillman reaction
1998
A Stereoselective Synthesis of α-(1-Hydroxyalkyl)-β-Substituted Acrylic Acid Esters
2000
Enantiospecific generation of anti-aldol adducts via conjugate addition to 5-methylene-1,3-dioxan-4-ones
1998
Reaction of a Cyclic Oxosulfonium Ylide with Acetates of the Baylis-Hillman Adducts: Tandem Michael−Intramolecular Corey-Chaykovsky Reactions
1999
A Novel Catalytic Cycle for the Synthesis of Epoxides Using Sulfur Ylides
1996
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
Asymmetric Baylis–Hillman reaction using sugar acrylates—synthesis of optically active α-methylene-β-hydroxy alkanoates
2001
Organocatalytic Asymmetric Transferhydrogenation of β-Nitroacrylates: Accessing β2-Amino Acids
2008 StandoutNobel
IDPi Catalysis
2019 StandoutNobel
Titanium(IV) chloride, zirconium(IV) chloride or boron trichloride and phosphine-promoted Baylis–Hillman reaction of aldehydes with α,β-unsaturated ketone
2001
Pyridinium ionic liquids-accelerated amine-catalyzed Morita–Baylis–Hillman reaction
2006
Highly diastereoselective coupling reactions between chiral benzaldehyde tricarbonylchromium complexes and activated double bonds
1993
The Baylis–Hillman chemistry in aqueous media: elucidation of mechanism for synthesis of ether side-product leads to an efficient approach to C–O bond formation
2003
Reaction of Baylis–Hillman products with Swern and Dess–Martin oxidants
2001
Dramatic Rate Acceleration of the Baylis−Hillman Reaction in Homogeneous Medium in the Presence of Water
2002
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
Ionic Liquid Metal-Conjugates: Formation of an Imidazolium Dirhodium(II) Carboxylate
2006
Asymmetric creation of quaternary carbon centers by enantiotopically selective aromatic C-H insertion catalyzed by chiral dirhodium(II) car☐ylates
1995
Synthèse de γ-lactames et de perhydro-1,2-pyridazin-3-ones polyfonctionnels.
1992
Ionic liquids as a recyclable reaction medium for the Baylis–Hillman reaction
2001
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
Baylis–Hillman reactions of N-arylidenediphenylphosphinamides with methyl vinyl ketone, methyl acrylate, and acrylonitrile
2002
Catalytic asymmetric oxonium ylide - [2,3] sigmatropic rearrangement with diazocarbonyl compounds: First use of C2-symmetry in Rh(II) carboxylates
1997
The reaction of the Baylis-Hillman adducts of N-tosylimines with N,N-dimethylformamide dimethylacetal
1999
Predicting the Diastereoselectivity of Rh-Mediated Intramolecular C−H Insertion
1996
An intramolecular Baylis-Hillman reaction
1992
New discovery in the traditional Baylis-Hillman reaction of arylaldehydes with methyl vinyl ketone
2001
Imidazole-catalysed Baylis–Hillman reactions: a new route to allylic alcohols from aldehydes and cyclic enones
2002
A Convenient Synthesis ofα-Halomethylene Aldols orβ-Halo-α-(hydroxyalkyl)acrylates Using the Chalcogeno-Baylis-Hillman Reaction
2000
New chiral rhodium(II) carboxylates and their use as catalysts in carbenoid transformations
1996
Combined Experimental and Computational Studies of Heterobimetallic Bi−Rh Paddlewheel Carboxylates as Catalysts for Metal Carbenoid Transformations
2009
Rh(II)-Catalyzed Reaction Of Some α‘,α‘- and β‘-Branched-O-Alkyl α-(Alkoxycarbonyl)-α-diazoacetates
1997
One-pot inter- and intramolecular Friedel–Crafts reactions in Baylis–Hillman chemistry: a novel facile synthesis of ( E )-2-arylideneindan-1-ones
2001
“Matched/Mismatched” Diastereomeric Dirhodium(II) Carboxamidate Catalyst Pairs. Structure−Selectivity Correlations in Diazo Decomposition and Hetero-Diels−Alder Reactions
2005
The Baylis-Hillman reaction: A novel carbon-carbon bond forming reaction
1996 Standout
Enantioselective synthesis of vinylcyclopropanes by rhodium(II) catalyzed decomposition of vinyldiazomethanes in the presence of alkenes
1993
Synthesis of 3-quinolinecarboxylic acid esters from the Baylis–Hillman adducts of 2-halobenzaldehyde N-tosylimines
2001
Rate Acceleration of the Baylis−Hillman Reaction in Polar Solvents (Water and Formamide). Dominant Role of Hydrogen Bonding, Not Hydrophobic Effects, Is Implicated
2001
Addition of Acrylamide to Amino Aldehydes to Generate Non-Baylis-Hillman Adducts. Formation of Novel N-Acylhemiaminals
1998
Applications of Baylis–Hillman chemistry: enantioselective synthesis of (−)-methyl 3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates via chiral leaving group strategy
2001
Effective enantioselective approach to α-aminoalkylacrylic acid derivatives via a synthetic equivalent of an asymmetric Baylis–Hillman reaction: application to the synthesis of two C-2′ hydroxymethyl analogues of docetaxel
1996
Copper-catalyzed asymmetric conjugate addition of Grignard reagents to cyclic enones
2004 StandoutNobel
A new protocol for the syntheses of (E)-3-benzylidenechroman-4-ones: a simple synthesis of the methyl ether of bonducellin
1998
First attempts at differential diastereoselection in catalytic reactions of N-chirally substituted dirhodium(ii) tetrakis[methyl 2-oxoimidazolidine-4(S)-carboxylates] with diazoacetates
2001
Theoretical Studies on Diastereo‐ and Enantioselective Rhodium‐Catalyzed Cyclization of Diazo Compound via Intramolecular CH Bond Insertion
2003
An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction
2003
Asymmetric Baylis–Hillman reactions: catalysis using a chiral pyrrolizidine base
1998
Synthesis of β-iodo-α-(hydroxyalkyl)acrylates: a convenient and stereoselective reaction
2002
Applications of the Baylis–Hillman reaction 2: a simple stereoselective synthesis of (E)- and (Z)-trisubstituted alkenes
1994
Asymmetric metal-catalysed epoxidation of electron-deficient olefins
1991
TiCl4-Mediated Baylis–Hillman and aldol reactions without the direct use of a Lewis base
2000
The Enantioselective Chalcogeno-Baylis-Hillman Reaction Using a Chiral Hydroxy Chalcogenide-TiCl4 Complex
1999
Synergy or Competition between Palladium-Catalysis and KF/Alumina-Mediation for the Allylic Substitution of the Acetates of Baylis–Hillman Adducts by Phenols
2000
Synthesis of diaza [7,7] paracyclophanetetraene and diaza [7,2,7,2] paracyclophanehexaene
1989
The Johnson-Claisen rearrangement of 3-hydroxy-2-methylenealkanenitriles: Stereoselective synthesis of functionalized trisubstituted alkenes
1995
Asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-β-lactams via novel, highly stereoselective Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2-azetidinones
1999
1,2-Asymmetric induction in radical reactions of β-amino acid derivatives
1995
Enantioselective Syntheses of 2-Deoxyxylono-1,4-lactone and 2-Deoxyribono-1,4-lactone from 1,3-Dioxan-5-yl Diazoacetates
1999
Combinatorial Liquid-Phase Synthesis of [1,4]Oxazepine-7-ones via the Baylis−Hillman Reaction
2000
The Development of the Asymmetric Morita—Baylis—Hillman Reaction Catalyzed by Chiral Brønsted Acids
2004
Aza‐Baylis–Hillman Reactions of N‐(Arylmethylene)diphenylphosphinamides with Activated Olefins in the Presence of Various Lewis Bases
2004
Total Synthesis of (S)-(+)-Imperanene. Effective Use of Regio- and Enantioselective Intramolecular Carbon−Hydrogen Insertion Reactions Catalyzed by Chiral Dirhodium(II) Carboxamidates
2002
Enantioselectively catalyzed intramolecular cyclopropanations of unsaturated diazo carbonyl compounds
1990
An expedient synthesis of 2-substituted naphthalenes from the Baylis–Hillman adducts
2001
THE BAYLIS—HILLMAN REACTION: TiCl4MEDIATED COUPLING OF ALKYL VINYL KETONES WITH α-KETO ESTERS AND ALDEHYDES
2001
The chalcogeno-Baylis–Hillman reaction of ketones and α-dicarbonyl compounds
2002
Palladium Catalysed Reactions of Baylis-Hillman Products: Synthesis of Some Useful Intermediates
1998
New aspects of catalytic asymmetric cyclopropanation
1998
Dynamic Control of Chiral Space in a Catalytic Asymmetric Reaction Using a Molecular Motor
2011 StandoutScienceNobel
A new catalytic transformation of diazo esters: hydride abstraction in dirhodium(II)-catalysed reactions
1995
Synthetic Applications of the Baylis–Hillman Adducts: A Simple Stereoselective Synthesis of (E)-3-(Nitroxymethyl)alk-3-en-2-ones
2000
Recent advances in the stereoselective synthesis of β-amino acids
2002
Arylation of the Baylis-Hillman adducts
1998
A simple preparation of syn-NH-amide aldols and amide-Baylis–Hillman adducts via a Michael–aldol tandem process
2000
The Baylis-Hillman reaction: An expedient synthesis of (Z)-keto allyl bromides and chlorides
1999
High Selectivity from Configurational Match/Mismatch in Carbon−Hydrogen Insertion Reactions of Steroidal Diazoacetates Catalyzed by Chiral Dirhodium(II) Carboxamidates
2001
The Friedel-Crafts reaction of the Baylis-Hillman adducts
1997
Synthesis of Chiral Hydroxyl Phospholanes from d -mannitol and Their Use in Asymmetric Catalytic Reactions
2000
Synthesis of N-substituted 1,4-dihydroquinolines from the Baylis–Hillman acetates via the successive SN2′–SNAr isomerization strategy
2001
(R)1‐(+)1‐Pantolactone Acrylate as a Chiral Auxiliary in the Baylis‐Hillman Reaction
1993
Enantiocontrol in intramolecular cyclopropanation of diazoketones. Conformational control of metal carbene alignment
1997
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
2010 Standout
New Strategic Reactions for Organic Synthesis: Catalytic Asymmetric C−H Activation α to Nitrogen as a Surrogate for the Mannich Reaction
2003
Synthesis of tricyclopolyprenols via a radical addition and a stereoselective elimination. Part I: Methodology
1998
Intramolecular Diels–Alder reaction of a sulphonyl-activated 1,3,9-triene
1990
Recent Advances in the Baylis−Hillman Reaction and Applications
2003 Standout
Carbamate-directed stereoselective hydrogenation and kinetic resolution of N-protected α-(α-aminoalkyl)acrylates
1991
Enantio- and Diastereoselective Catalytic Carboalumination of 1-Alkenes and α,ω-Dienes with Cationic Zirconocenes: Scope and Mechanism
1998
High Substrate/Catalyst Organocatalysis by a Chiral Brønsted Acid for an Enantioselective Aza‐Ene‐Type Reaction
2006
Straightforward Asymmetric Entry to Highly Functionalized Medium-Sized Rings Fused to β-Lactams via Chemo- and Stereocontrolled Divergent Radical Cyclization of Baylis−Hillman Adducts Derived from 4-Oxoazetidine-2-carbaldehydes
2001
Naturally occurring quinones as potential bioreductive alkylating agents
1981
Application of non-imidazolium-based ionic liquid in the Baylis–Hillman reactions: Rate and yield promoted
2006
Catalytic Enantioselective C−H Activation by Means of Metal−Carbenoid-Induced C−H Insertion
2003
Synthesis of 3-Arylidene-3,4-Dihydrocoumarins
1994
The Vinylogous Intramolecular Morita−Baylis−Hillman Reaction: Synthesis of Functionalized Cyclopentenes and Cyclohexenes with Trialkylphosphines as Nucleophilic Catalysts
2002
α-hydroxy esters as inexpensive chiral auxiliaries in rhodium(II)-catalyzed cyclopropanations with vinyldiazomethanes
1991
Organocatalytic Michael Cycloisomerization of Bis(enones): The Intramolecular Rauhut−Currier Reaction
2002
A method for rhodium(II)-catalyzed aziridination of olefins
1996
The use of enantiomerically pure N-sulfinimines in asymmetric Baylis–Hillman reactions
2002
Synthesis and metathesis reactions of a phosphine-free dihydroimidazole carbene ruthenium complex
2000
Asymmetric rhodium carbene insertion into the SiH bond: identification of new dirhodium(II) carboxylate catalysts using parallel synthesis techniques
2003
Synthesis of stereochemically defined (E)-cinnamyl alcohol derivatives from the Baylis–Hillman adducts
2000
Der katalytische enantioselektive Aufbau von Molekülen mit quartären Kohlenstoff-Stereozentren
1998 Nobel
Enhancement of enantiocontrol/diastereocontrol in catalytic intramolecular cyclopropanation and carbon-hydrogen insertion reactions of diazoacetates with Rh2(4S-MPPIM)4
1995
Enantioselective catalytic intramolecular cyclopropanation of allylic α-diazopropionates optimized with dirhodium(II) tetrakis[methyl 2-oxazolidinone-4(S or R)-carboxylate]
1995
Works of Gregory Roos being referenced
Compendium of chiral auxiliary applications
2002
Stereoselective Addition of Methyl Acrylate to α-Amino Aldehydes
1991
1,2-Addition of Activated Vinyl Carbanions to α,β-Unsaturated Carbonyls
1989
Asymmetric Synthesis of 2-Substituted Acrylate Esters
1987
Temperature and Ultrasound Rate Enhancement in the Baylis-Hillman Reaction
1993
Diastereocontrol for Highly Enantioselective Carbon-Hydrogen Insertion Reactions of Cycloalkyl Diazoacetates
1994
A Facile Synthesis of Homochiral Rh(II) Carboxylates
1992
Improved enantioselection for chiral dirhodium(II) carboxamide-catalysed carbon-hydrogen insertion reactions of tertiary alkyl diazoacetates
1995
Cyclization of a chiral α‐(δ′‐benzyloxyalkyl)acrylate to a novel tetrahydrofuran derivative
1990
A Facile, Efficient Route to Methyl α-Hydroxymethylacrylate and Methyl α-Halomethylacrylates
1987
(4,0)-Dirhodium(II) tetrakis[methyl 1-acetyl-2-oxoimidazolidine-4(S)-carboxylate]. Implications for the mechanism of ligand exchange reactions
1997
Stereoselective Synthesis of α-Methylene-β-Hydroxy-γ-Alkoxy Esters and Ketones
1988
2-Substituted 2-Propenoic Acid Esters via Reaction of a Masked Acrylate Ester with Carbonyl Compounds
1986
A Facile Diagnostic 1H NMR Method for Syn and anti Hydroxy Systems
1992
Models for the syntheses of the naphthoquinonoid antibiotics, the juglomycins A and B.
1977
Synthetic potential of the tertiary-amine-catalysed reaction of activated vinyl carbanions with aldehydes
1988 Standout
Diastereoselective Addition of Imidazolidin-2-One Controlled Enolates to Activated Imines
1999
Asymmetric synthesis in carbon–carbon bond forming reactions of α-diazoketones catalysed by homochiral rhodium(II ) carboxylates
1990
Synthesis of novel C2-symmetric ligands based on (R,R)- and (S,S)-diphenyl-1,3-propanediol
1999
Synthesis and Structures of (2,2-cis)-Dirhodium(II) Tetrakis[methyl 1-acyl-2-oxoimidazolidine-4(S)-carboxylates]. Chiral Catalysts for Highly Stereoselective Metal Carbene Transformations
1996
Ephedrine‐Derived Imidazolidin‐2‐ones. Broad Utility Chiral Auxiliaries in Asymmetric Synthesis
1993
Synthesis of the C2Symmetric 1,3-Dicyclohexyl-1,3-Propanediol and Diamine Enantiomers
1999
Enantioselective Approaches to Rhodium Catalysed Aldol-Type Reactions
1993
Synthesis of 3-Hydroxy-2-Methylene Carbonyl Compounds - Effect of Catalyst and Substrate on Reaction Rate
1988