Citation Impact
Citing Papers
Crystal Structure of Human Toll-Like Receptor 3 (TLR3) Ectodomain
2005 Science
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
The molecular structure of the Toll-like receptor 3 ligand-binding domain
2005
Atypical Memory B Cells Are Greatly Expanded in Individuals Living in a Malaria-Endemic Area
2009
Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses
2008
Elucidation of the MD-2/TLR4 Interface Required for Signaling by Lipid IVa
2008
NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury
2009
Latrophilins Function as Heterophilic Cell-adhesion Molecules by Binding to Teneurins
2013 StandoutNobel
Siglec functions of microglia
2014
In vitrokinetic studies on the mechanism of oxygen-dependent cellular uptake of copper radiopharmaceuticals
2009
Circulating mitochondrial DAMPs cause inflammatory responses to injury
2010 StandoutNature
The Retinal Pigment Epithelium in Visual Function
2005 Standout
Molecular imaging with copper-64
2004
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
Cu–ATSM: A radiopharmaceutical for the PET imaging of hypoxia
2007
Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses
2004
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Toll-like receptor pathways in the immune responses to mycobacteria
2004
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The leucine-rich repeat structure
2008
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Specific memory within innate immune systems
2005
Novel chelating agents for potential clinical applications of copper
2002
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Mechanisms of plant resistance to viruses
2005
Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey
2004 Nature
Biochemical and Functional Analyses of the Human Toll-like Receptor 3 Ectodomain
2007
TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system
2007
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Endotoxin recognition and signal transduction by the TLR4/MD2-complex
2004
High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy
2014 StandoutNobel
Transcriptional signaling by double-stranded RNA: role of TLR3
2005
Pattern Recognition Receptors and Inflammation
2010 Standout
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
2005
Bifunctional chelators for copper radiopharmaceuticals: the synthesis of [Cu(ATSM)–amino acid] and [Cu(ATSM)–octreotide] conjugates
2006
Nonresolving Inflammation
2010 Standout
Intracellular Toll-like Receptors
2010 StandoutNobel
Using the Acropora digitifera genome to understand coral responses to environmental change
2011 StandoutNature
Influence of Interleukin 10 and Transforming Growth Factor-β on T Cell Stimulation through Allogeneic Retinal Pigment Epithelium Cells in vitro
2002
Structures of the Toll-like Receptor Family and Its Ligand Complexes
2008
Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3
2008
Examining the relationship between Cu-ATSM hypoxia selectivity and fatty acid synthase expression in human prostate cancer cell lines
2008
Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
2016
Toll-like receptor signalling
2004 Standout
Acetylacetonate bis(thiosemicarbazone) complexes of copper and nickel: towards new copper radiopharmaceuticals
2004
Spectroelectrochemical and Computational Studies on the Mechanism of Hypoxia Selectivity of Copper Radiopharmaceuticals
2008
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
The development of allergic inflammation
2008 StandoutNature
Ligand-induced conformational changes allosterically activate Toll-like receptor 9
2007
The immune gene repertoire encoded in the purple sea urchin genome
2006 Standout
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
2006 Standout
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
2008 Nature
A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition
2009
Copper Chelation Chemistry and its Role in Copper Radiopharmaceuticals
2006
A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression
2005
Matching chelators to radiometals for radiopharmaceuticals
2013 Standout
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines
2008
In vivo assessment of tumor hypoxia in lung cancer with 60Cu-ATSM
2003
Investigation into 64Cu-labeled Bis(selenosemicarbazone) and Bis(thiosemicarbazone) complexes as hypoxia imaging agents
2005
THERANOSTICS: From Molecular Imaging Using Ga-68 Labeled Tracers and PET/CT to Personalized Radionuclide Therapy - The Bad Berka Experience
2012
Identification of Bacterial Muramyl Dipeptide as Activator of the NALP3/Cryopyrin Inflammasome
2004
The Inflammasomes
2010 Standout
Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA
2005 StandoutNobel
Mast-cell responses to pathogens
2004
Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction
2003
RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga
2012
Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells
2009
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms
2003
Novel Roles in Human MD-2 of Phenylalanines 121 and 126 and Tyrosine 131 in Activation of Toll-like Receptor 4 by Endotoxin
2007
Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3
2005 Standout
Toll‐like receptors, endogenous ligands, and systemic autoimmune disease
2005
Signalling pathways and molecular interactions of NOD1 and NOD2
2005
Characterization of bovine Toll-like receptor 8: Ligand specificity, signaling essential sites and dimerization
2008
Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis
2016
Pathogen Recognition and Innate Immunity
2006 Standout
Cell line-dependent differences in uptake and retention of the hypoxia-selective nuclear imaging agent Cu-ATSM
2005
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Inflammasomes in health and disease
2012 StandoutNature
Redox activation of metal-based prodrugs as a strategy for drug delivery
2012
Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68
2012
Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells
2018
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Identification of an N-Terminal Recognition Site in TLR9 That Contributes to CpG-DNA-Mediated Receptor Activation
2009
CuII(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease
2019
Bonding and structure trends of thiosemicarbazone derivatives of metals—An overview
2008 Standout
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
In Vitro and In Vivo Evaluation of Bifunctional Bisthiosemicarbazone 64Cu-Complexes for the Positron Emission Tomography Imaging of Hypoxia
2008
Copper-64-pyruvaldehyde-bis(N(4)-methylthiosemicarbazone) for the prevention of tumor growth at wound sites following laparoscopic surgery: monitoring therapy response with microPET and magnetic resonance imaging.
2002
Molecular Pathogenesis ofShigellaspp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion
2008
Molecular Basis of Reduced Potency of Underacylated Endotoxins
2005
Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses
2010
Enhancing targeted radiotherapy by copper(II)diacetyl- bis(N4-methylthiosemicarbazone) using 2-deoxy-D-glucose.
2003
Structural trends in copper(ii ) bis(thiosemicarbazone) radiopharmaceuticals
2003
Comparison of Four 64Cu-Labeled Somatostatin Analogues in Vitro and in a Tumor-Bearing Rat Model: Evaluation of New Derivatives for Positron Emission Tomography Imaging and Targeted Radiotherapy
1999
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
The Master Switch: The Role of Mast Cells in Autoimmunity and Tolerance
2008
Rhodium Assisted C−H Activation of Benzaldehyde Thiosemicarbazones and Their Oxidation via Activation of Molecular Oxygen
2006
Synthesis, structure, spectroscopic properties and cytotoxic effect of some thiosemicarbazone complexes of palladium
2007
Controlling the Toll road to dendritic cell polarization
2004
Crystal Structures of Human MD-2 and Its Complex with Antiendotoxic Lipid IVa
2007 Science
The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
2009 StandoutNature
Novel binuclear copper(II) complexes of di-2-pyridyl ketone N(4)-methyl, N(4)-phenylthiosemicarbazone: Structural and spectral investigations
2005
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone).
2006
Macrocyclic Diamide Ligand Systems: Potential Chelators for 64Cu- and 68Ga-Based Positron Emission Tomography Imaging Agents
2009
Kinetics of Binding of LPS to Recombinant CD14, TLR4, and MD-2 Proteins
2007
Radiometal-Labeled Agents (Non-Technetium) for Diagnostic Imaging
1999
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
2006 StandoutNobel
Young Lives Lost as B Cells Falter: What We Are Learning About Antibody Responses in Malaria
2013
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Synthesis, X‐ray Crystallography, Spectroelectrochemistry and Computational Studies on Potential Copper‐Based Radiopharmaceuticals
2008
Copper(II) complexes derived from di-2-pyridyl ketone N(4),N(4)-(butane-1,4-diyl)thiosemicarbazone: Crystal structure and spectral studies
2006
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
The TLR3 signaling complex forms by cooperative receptor dimerization
2008
Functionalized Bis(thiosemicarbazonato) Complexes of Zinc and Copper: Synthetic Platforms Toward Site-Specific Radiopharmaceuticals
2006
Hypoxia-Targeting Copper Bis(selenosemicarbazone) Complexes: Comparison with Their Sulfur Analogues
2003
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
T-Cell Suppression by Programmed Cell Death 1 Ligand 1 on Retinal Pigment Epithelium during Inflammatory Conditions
2009 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors
2007
Tumor uptake of copper-diacetyl-bis(N(4)-methylthiosemicarbazone): effect of changes in tissue oxygenation.
2001
Evidence that retinal pigment epithelium functions as an immune-privileged tissue.
2000
The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis
2011
Kinetically locked, trinuclear RuIImetallo-macrocycles—synthesis, electrochemical, and optical properties
2006
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Recent developments in the design of bifunctional chelators for metal-based radiopharmaceuticals used in Positron Emission Tomography
2012
Radiometals for Combined Imaging and Therapy
2012
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
Siglec‐1 and ‐2 as potential biomarkers in autoimmune disease
2016
A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding
2011 StandoutNobel
Investigations into some aryl substituted bis(thiosemicarbazones) and their copper complexes
2005
Works of Gregory Mullen being referenced
The TLR9 Ligand CpG Promotes the Acquisition of Plasmodium falciparum -Specific Memory B Cells in Malaria-Naive Individuals
2009
A Complex of Soluble MD-2 and Lipopolysaccharide Serves as an Activating Ligand for Toll-like Receptor 4
2004
Formulation of vaccines containing CpG oligonucleotides and alum
2007
National Electrical Manufacturers Association NU-4 Performance Evaluation of the PET Component of the NanoPET/CT Preclinical PET/CT Scanner
2011
Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: structure-activity relationships
2002
Efficient bifunctional gallium-68 chelators for positron emission tomography: tris(hydroxypyridinone) ligands
2011
Leucine-rich repeats and pathogen recognition in Toll-like receptors
2003
Retinal Pigment Epithelial Cells Modulate Lymphocyte Function at the Blood-Retina Barrier by Autocrine PGE2 and Membrane-Bound Mechanisms
1993
Design of hypoxia-targeting radiopharmaceuticals: selective uptake of copper-64 complexes in hypoxic cells in vitro
1998
Studies on the Mechanism of Hypoxic Selectivity in Copper Bis(Thiosemicarbazone) Radiopharmaceuticals
2002
Sialoadhesin – a macrophage‐restricted marker of immunoregulation and inflammation
2012
Electron Transfer Induced CS Bond Cleavage in Rhenium and Technetium Thioether Complexes: Structural and Chemical Evidence for π Back‐Donation to CS σ* Orbitals
1997
Cutting Edge: Histamine Inhibits IFN-α Release from Plasmacytoid Dendritic Cells
2003
An investigation of C–S bond activation in transition metal crown thioether complexes using extended Hückel theory and electrospray mass spectrometry
1999
The role of disulfide bonds in the assembly and function of MD-2
2003