Citation Impact
Citing Papers
Tumour-cell invasion and migration: diversity and escape mechanisms
2003 Standout
LOK Is a Novel Mouse STE20-like Protein Kinase That Is Expressed Predominantly in Lymphocytes
1997
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
1998 Standout
The GIT Family of ADP-ribosylation Factor GTPase-activating Proteins
2000 StandoutNobel
Different Molecular Mechanisms for Rho Family GTPase-dependent, Ca2+-independent Contraction of Smooth Muscle
1998
Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase
1998 Standout
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
1996
Rac and Rho: The Story Behind Melanocyte Dendrite Formation
2002
Structural Requirements for PAK Activation by Rac GTPases
1998
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles
2003
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?
1997
Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (γ-PAK)
1998
Identification and Molecular Cloning of a p21cdc42/rac1-activated Serine/Threonine Kinase That Is Rapidly Activated by Thrombin in Platelets
1995
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
The Caenorhabditis elegans p21-activated Kinase (CePAK) Colocalizes with CeRac1 and CDC42Ce at Hypodermal Cell Boundaries during Embryo Elongation
1996
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Interactions between Ras proteins and their effectors
1996
CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
2000 StandoutNobel
PSK, a Novel STE20-like Kinase Derived from Prostatic Carcinoma That Activates the c-Jun N-terminal Kinase Mitogen-activated Protein Kinase Pathway and Regulates Actin Cytoskeletal Organization
2000
Regulation and function of the JNK subgroup of MAP kinases
1997
Cdc42, Rac1, and Their Effector IQGAP1 as Molecular Switches for Cadherin-Mediated Cell–Cell Adhesion
1999
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
The Dbl family of oncogenes
1996
Regulation of Cross-linking of Actin Filament by IQGAP1, a Target for Cdc42
1997
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck
1997
ROCKs: multifunctional kinases in cell behaviour
2003 Standout
Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins
1997
PAK promotes morphological changes by acting upstream of Rac
1998
Multiple Interactions of PRK1 with RhoA
1998
The Cdc42/Rac Interactive Binding Region Motif of the Wiskott Aldrich Syndrome Protein (WASP) Is Necessary but Not Sufficient for Tight Binding to Cdc42 and Structure Formation
1998
Rho GTPases and signaling networks
1997 Standout
Regulation of Phosphorylation Pathways by p21 GTPases
1996
The Renaturable 69- and 63-kDa Protein Kinases That Undergo Rapid Activation in Chemoattractant-stimulated Guinea Pig Neutrophils Are p21-Activated Kinases
1996
PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors
1998
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans
2002 StandoutNobel
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
1997 StandoutNature
Phosphorylation of CPI17 and myosin binding subunit of type 1 protein phosphatase by p21-activated kinase
2002
Rho and Rac Take Center Stage
2004 Standout
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Mis-specification of cortical identity in a fission yeast PAK mutant
1999 StandoutNobel
Cloning and Characterization of a Novel Cdc42-associated Tyrosine Kinase, ACK-2, from Bovine Brain
1997
Human JIK, a Novel Member of the STE20 Kinase Family That Inhibits JNK and Is Negatively Regulated by Epidermal Growth Factor
1999
doublecortin, a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein
1998
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
Inhibition of Contraction and Myosin Light Chain Phosphorylation in Guinea‐Pig Smooth Muscle by p21‐Activated Kinase 1
2003
Identification of IQGAP as a Putative Target for the Small GTPases, Cdc42 and Rac1
1996
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
MOM-4, a MAP Kinase Kinase Kinase–Related Protein, Activates WRM-1/LIT-1 Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain
2008 StandoutNobel
Differential Effects of PAK1-activating Mutations Reveal Activity-dependent and -independent Effects on Cytoskeletal Regulation
1998
The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic Cells
2001 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
NADPH Oxidase: An Update
1999 Standout
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Genetic Evidence for Pak1 Autoinhibition and Its Release by Cdc42
1999
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Rho GTPases and their effector proteins
2000
Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis
1997
DNA Synthesis and Neuronal Apoptosis Caused by Familial Alzheimer Disease Mutants of the Amyloid Precursor Protein Are Mediated by the p21 Activated Kinase PAK3
2003
A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1
1998
Rho GTPases and their effector proteins
2000 Standout
Endothelial cell retraction is induced by PAK2 monophosphorylation of myosin II
2000
Products of Sphingolipid Catabolism Block Activation of the p21-Activated Protein Kinases in Neutrophils
1998
Regulation of polymorphonuclear leukocyte degranulation and oxidant production by ceramide through inhibition of phospholipase D
2002 StandoutNobel
Fibronectin Matrix Regulates Activation of RHO and CDC42 GTPases and Cell Cycle Progression
1998
The p160 RhoA-Binding Kinase ROKα Is a Member of a Kinase Family and Is Involved in the Reorganization of the Cytoskeleton
1996
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
2000 StandoutScience
Integrin Signaling
1999 StandoutScience
Mutations That Affect Dimer Formation and Helicase Activity of the Hepatitis C Virus Helicase
2001 StandoutNobel
Emerging from the Pak: the p21-activated protein kinase family
1997
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
Expression of Constitutively Active α-PAK Reveals Effects of the Kinase on Actin and Focal Complexes
1997
ThreeC. elegansRac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis
2001 StandoutNobel
The Guanine Nucleotide-Binding Switch in Three Dimensions
2001 StandoutScience
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Localization of p21-Activated Kinase 1 (PAK1) to Pinocytic Vesicles and Cortical Actin Structures in Stimulated Cells
1997
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
1999 Standout
Regulation of the Cytoskeleton and Cell Adhesion by the Rho Family GTPases in Mammalian Cells
1999
Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
1998 StandoutNobel
Lck Regulates Vav Activation of Members of the Rho Family of GTPases
1997
Actions of Rho Family Small G Proteins and p21-Activated Protein Kinases on Mitogen-Activated Protein Kinase Family Members
1996
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Signal Transduction through MAP Kinase Cascades
1998 Standout
Cdc42: An Essential Rho-Type GTPase Controlling Eukaryotic Cell Polarity
1999
Mechanisms of Endocytosis
2009 Standout
Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS inCaenorhabditis elegans
2015 StandoutNobel
Filopodia are conduits for melanosome transfer to keratinocytes
2002
Works of Gregory Michael being referenced
Molecular Cloning of a New Member of the p21-Cdc42/Rac-activated Kinase (PAK) Family
1995