Citation Impact
Citing Papers
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Agonist and antagonist effects of 3-PPP enantiomers on functional dopamine autoreceptors and postsynaptic dopamine receptors in vitro
1985
The novel anticonvulsant MK-801 interacts with central phencyclidine recognition sites in rat brain
1987
Hippocampal synaptic plasticity and NMDA receptors: a role in information storage?
1990
Glutamate Antagonist Therapy Reduces Neurologic Deficits Produced by Focal Central Nervous System Ischemia
1988
Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice
1989 StandoutNobel
Time course effects of MK-801: The relationship between brain neurochemistry and behavior
1995
Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease
1990
Rodent data and general hypothesis: antipsychotic action exerted through 5-HT2A receptor antagonism is dependent on increased serotonergic tone
1998 StandoutNobel
Differential behavioural and neurochemical effects of competitive and non-competitive NMDA receptor antagonists in rats
1992
Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats
1989
Effects of dopamine D1 and D2 receptor blockade on MK-801-induced hyperlocomotion in rats
1993
Phencyclidine- and Dizocilpine-Induced Hyperlocomotion Are Differentially Mediated
1994
Are the disparate pharmacological profiles of competitive and un-competitive NMDA antagonists due to different baseline activities of distinct glutamatergic pathways? (Hypothesis)
1993
MK-801-induced stereotypy and its antagonism by neuroleptic drugs
1990
On the roles of dopamine D-1 vs. D-2 receptors for the hyperactivity response elicited by MK-801
1994 StandoutNobel
The glutamate antagonist MK‐801 reduces focal ischemic brain damage in the rat
1988
MK-801 blocks NMDA receptor-mediated synaptic transmission and long term potentiation in rat hippocampal slices
1987
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
2005 Standout
Thermal biology of the laboratory rat
1990
Schizophrenia: A Subcortical Neurotransmitter Imbalance Syndrome?
1990
Comparison of the behavioral and biochemical effects of the NMDA receptor antagonists, MK-801 and phencyclidine
1989
The Opioid System and Temperature Regulation
1988
A3-adenosine receptors: Design of selective ligands and therapeutic prospects
1995
The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor
1989
Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems
1990
The effect of the excitatory amino acid receptor antagonist dizocilipine maleate (MK-801) on hemispheric cerebral blood flow and metabolism in dogs: modification by prior complete cerebral ischemia
1989
MK-801, an Excitatory Amino Acid Antagonist, Does Not Improve Neurologic Outcome following Cardiac Arrest in Cats
1989
Independent rate and temporal coding in hippocampal pyramidal cells
2003 StandoutNatureNobel
Comparison of competitive and uncompetitive NMDA receptor antagonists with regard to monoaminergic neuronal activity and behavioural effects in rats
1993
Site-directed Mutagenesis Identifies Residues Involved in Ligand Recognition in the Human A2a Adenosine Receptor
1995
Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
1997 Standout
Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP‐ATP and enhancement by the P2X3 allosteric modulator, cibacron blue
2001
Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia
2000 StandoutNobel
A synaptic model of memory: long-term potentiation in the hippocampus
1993 StandoutNature
The receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats
1991
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Effect of chronic treatment with dizocilpine (MK-801) on the behavioral response to dopamine receptor agonists in the rat
1992
Induction of Apoptosis in HL-60 Human Promyelocytic Leukemia Cells by Adenosine A3Receptor Agonists
1996 StandoutNobel
Regional effects of MK-801 on dopamine and its metabolites studied by in vivo microdialysis
1992
Effect of MK-801 on endogenous dopamine release in vivo
1990
Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats
1992
Motor responses to dopamine D1 and D2 agonists in the reserpine-treated mouse are affected differentially by the NMDA receptor antagonist MK 801
1992
A comparison between the non-competitive NMDA antagonist dizocilpine (MK-801) and the competitive NMDA antagonist D-CPPene with regard to dopamine turnover and locomotor-stimulatory properties in mice
1991
Cascade Reactions in Total Synthesis
2006 Standout
Antipsychotic Properties of the Partial Dopamine Agonist (−)-3-(3-Hydroxyphenyl)-N-n-Propylpiperidine (Preclamol) in Schizophrenia
1998 StandoutNobel
Role of excitatory amino acids in the ventral tegmental area for central actions of non-competitive NMDA-receptor antagonists and nicotine
1998
Electrophysiological effects of MK-801 on rat nigrostriatal and mesoaccumbal dopaminergic neurons
1992
Neurotransmitter interactions in schizophrenia—therapeutic implications
1999 StandoutNobel
Blockade of transmission at NMDA receptors facilitates the electrical and synthetic activity of ascending serotoninergic neurones
1994
Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and on the metabolism of dopamine in various brain areas of mice
1991
Learning and Memory Deficits in Notch Mutant Mice
2003 StandoutNobel
Effects of D-cycloserine and (+)-HA-966 on the locomotor stimulation induced by NMDA antagonists and clonidine in monoamine-depleted mice
1994 StandoutNobel
Neurotransmitter aberrations in schizophrenia: New perspectives and therapeutic implications
1997 StandoutNobel
Allosteric modulation of A2A adenosine receptors by amiloride analogues and sodium ions
2000
The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice
1989 StandoutNobel
MK-801-induced hyperlocomotion: Differential effects of M100907, SDZ PSD 958 and raclopride
1997 StandoutNobel
Glutamate receptor function in learning and memory
2003
Functional expression of brain cholecystokinin and bombesin receptors in Xenopus oocytes
1988
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
MK-801 attenuates the dopamine-releasing but not the behavioral effects of methamphetamine: an in vivo microdialysis study
1991
Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models
1988
Path integration and the neural basis of the 'cognitive map'
2006 StandoutNobel
Effects of dizocilpine (MK-801) on rat midbrain dopamine cell activity: differential actions on firing pattern related to anatomical localization
1993
Prazosin inhibits MK-801-induced hyperlocomotion and dopamine release in the nucleus accumbens
1996
Synthesis of angular-substituted tetracyclic azepino-indole derivatives via N-acyliminium ion cyclization
1999
Effects of B‐HT 920 and B‐HT 933 on Dopamine and Noradrenaline Autoreceptors in the Rat Brain
1983
Binding Characteristics and Interactions of Depressant Drugs with [35S]t‐Butylbicyclophosphorothionate, a Ligand that Binds to the Picrotoxinin Site
1984
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
1996 StandoutNobel
Is TL-99 a selective presynaptic dopamine receptor agonist?
1982
Differential effects of the enantiomers of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP) at dopamine receptors sites
1983
Characterization of dopamine autoreceptor and [3H]spiperone binding sites in vitro with classical and novel dopamine receptor agonists
1983
Molecular Physiology of P2X Receptors
2002 Standout
Effects of apomorphine, TL-99 and 3-PPP on yawning in rats
1984
NMDA Receptor Antagonism Blocks Experience-Dependent Expansion of Hippocampal “Place Fields”
2001
Marked locomotor stimulation in monoamine-depleted mice following treatment with atropine in combination with clonidine
1989 StandoutNobel
Recent Advances in Asymmetric Catalytic Metal Carbene Transformations
1998 Standout
The opiomelanotropinergic neuronal and endocrine systems
1982
Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 5. Study of the Physicochemical Influence of the Pharmacophore on 5-HT1A/α1-Adrenergic Receptor Affinity: Synthesis of a New Derivative with Mixed 5-HT1A/D2 Antagonist Properties
2000
A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus
1985 Science
Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers
1983
(+)-UH 232 and (+)-UH 242: Novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors
1986 StandoutNobel
Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memory
2003 StandoutNobel
Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go.
1993 StandoutNobel
Place Cells, Grid Cells, and the Brain's Spatial Representation System
2008 StandoutNobel
Cascade Processes of Metallo Carbenoids
1996 Standout
Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants.
1984
Hippocampus-independent phase precession in entorhinal grid cells
2008 StandoutNatureNobel
Interaction of (+)- and (−)-3-PPP with the dopamine receptor in the anterior pituitary gland
1984
Avoidance and ICSS behavioral models dissociate TL-99 and 3-PPP from dopamine receptor antagonists
1983
Blockade of MK-801 induced ipsiversive turning in 6-OHDA lesioned rats by α1-adrenoceptor antagonists
1984
Vasopressin analgesia: Specificity of action and non-opioid effects
1984
Similarities of the effects of apomorphine and 3-PPP on serotonin neurons
1983
Differential behavioural effects of dopamine agonists in developing rats: A study of 3-PPP enantiomers
1983
Sub-chronic administration of (?)-3-PPP and central dopamine receptor sensitivity changes
1985 StandoutNobel
Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor
1986 StandoutScience
Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition.
1996
Stimulation of presynaptic dopamine autoreceptors by 4-(2-di-n-propylaminoethyl) indole (DPAI)
1984
The behavioural effects of MK-801 in rats: involvement of dopaminergic, serotonergic and noradrenergic systems
1992
Dopamine-receptor agonists: Mechanisms underlying autoreceptor selectivity
1985 StandoutNobel
Cyclizations of N-Acyliminium Ions
2004 Standout
Action of putative dopamine receptor agonists, TL-99, 3-PPP and RDS-127 on substantia nigra neurons
1984
Ischemic Cell Death in Brain Neurons
1999 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Dopamine receptors involved in prolactin secretion pharmacologically characterized by means of 3-PPP enantiomers
1983 StandoutNobel
Dopamine receptor agonists: Intrinsic activity vs. state of receptor
1983 StandoutNobel
Restoration of shock‐suppressed behavior by treatment with (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties
1982
Protective Effect of the Glutamate Antagonist, MK-801 in Focal Cerebral Ischemia in the Cat
1988
The effect of the enantiomers of 3-PPP on conditioned avoidance responding in the rat
1983 StandoutNobel
Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP
1983 StandoutNobel
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Strain-dependent effects of MK-801 on passive avoidance behaviour in mice: interactions with morphine and immobilization stress
1999
Postischemic Blockade of AMPA but Not NMDA Receptors Mitigates Neuronal Damage in the Rat Brain following Transient Severe Cerebral Ischemia
1992
8-(1H-Imidazol-1-yl)-7-nitro-4(5H)-imidazo[1,2-a]quinoxalinone and Related Compounds: Synthesis and Structure−Activity Relationships for the AMPA-type Non-NMDA Receptor
1997
Concurrent locomotor stimulation and decrease in dopamine release in rats and mice after treatment with the competitive NMDA receptor antagonists D-CPPene and CGS 19755
1996
Effects of putative dopamine autoreceptor agonists in pharmacological models related to dopaminergic and neuroleptic activity
1982
Postsynaptic dopamine agonistic effects of 3-PPP enantiomers revealed by bilateral 6-hydroxy-dopamine lesions and by chronic reserpine treatment in rats
1984
Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil
1987
Reactivation of Hippocampal Ensemble Memories During Sleep
1994 StandoutScience
An electrophysiological analysis of the actions of the 3-PPP enantiomers on the nigrostriatal dopamine system
1985 StandoutNobel
Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin
1987 StandoutScience
Electrophysiological effects of the enantiomers of 3-PPP on neurons in the locus coeruleus of the rat
1986
Association Between Brain Temperature and Dentate Field Potentials in Exploring and Swimming Rats
1993 StandoutScienceNobel
Works of Gregory E. Martin being referenced
Adenosine agonists reduce conditioned avoidance responding in the rat
1993
Azepinoindole derivatives with high affinity for brain dopamine and serotonin receptors
1998
Differential effects of the adenosine A1 receptor allosteric enhancer PD 81,723 on agonist binding to brain and adipocyte membranes
1999
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy
1989
demonstration of the enhancement of MK-801 by L-glutamate
1989
Central sympathomimetic activity of (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo [a, d]cyclohepten‐5,10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties
1982
Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties
1982
Hyperthermia evoked by the intracerebral injection of morphine sulphate in the rat: The effect of restraint
1978
Different actions of TL-99 and 3-PPP in producing contraversive turning in the 6-OHDA-lesioned rat
1983
Differences in the pharmacological actions of intrathecally administered neurotensin and morphine
1982
Synthesis of (7R)-7H-indolo[3,4-gh][1,4]benzoxazines, a new class of D-heteroergolines with dopamine agonist activity
1983
Increase in brain 125I-cholecystokinin (CCK) receptor binding following chronic haloperidol treatment, intracisternal 6-hydroxydopamine or ventral tegmental lesions
1983
Action of intracerebrally injected β-endorphin on the rat's core temperature
1979
Catecholamine Release within the Striatum of the Freely Moving Rat
1986
Restraint alters the effects of morphine and heroin on core temperature in the rat
1977
Pharmacological profiles of the putative dopamine autoreceptor agonists 3-PPP and TL-99
1981
Effect on core temperature of restraint after peripherally and centrally injected morphine in the Sprague-Dawley rat
1979
ANTINOCISPONSIVE EFFECTS OF NEUROTENSIN AND NEUROTENSIN‐RELATED PEPTIDES
1982