Citation Impact
Citing Papers
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Descending control of persistent pain: inhibitory or facilitatory?
2004
Depletion of central β-endorphin blocks midbrain stimulation produced analgesia in the freely-moving rat
1986
Mortality among head trauma patients taking preinjury antithrombotic agents: a retrospective cohort analysis from a Level 1 trauma centre
2016
DECONSTRUCTING ENDOGENOUS PAIN MODULATIONS
2005
Lumbar intrathecal administration of naloxone antagonizes analgesia produced by electrical stimulation of the hypothalamic arcuate nucleus in pentobarbital-anesthetized rats
1990
Endogenous opioid-mediated inhibition of putative pain-modulating neurons in rat rostral ventromedial medulla
1996
Coping with chronic pain: a critical review of the literature
1991 Standout
The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes
2003 Standout
Cellular mechanism for anti-analgesic action of agonists of the κ-opioid receptor
1997 Nature
Inhibition of mesencephalic morphine analgesia by methysergide in the medial ventral medulla of rats
1992
Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat
2000
Roles for Pain Modulatory Cells during Micturition and Continence
2005
The Long-Term Outcome of Microvascular Decompression for Trigeminal Neuralgia
1996 Standout
The benzodiazepine inverse agonist DMCM as an unconditional stimulus for fear-induced analgesia: Implications for the role of GABA-sub(A ) receptors in fear-related behavior.
1992
Arcuate nucleus projections to brainstem regions which modulate nociception
1991
Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short‐Form McGill Pain Questionnaire (SF‐MPQ), Chronic Pain Grade Scale (CPGS), Short Form‐36 Bodily Pain Scale (SF‐36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP)
2011 Standout
Ventromedial medulla: Pain modulation and beyond
2005
Mortality after ground-level fall in the elderly patient taking oral anticoagulation for atrial fibrillation/flutter
2014
Brain stem activation in spontaneous human migraine attacks
1995 Standout
The medullary dorsal reticular nucleus facilitates pain behaviour induced by formalin in the rat
1999
Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies
2002 Standout
Traumatic brain injury in older adults: characteristics, causes and consequences
2012
Modulation of neuronal activity in the nucleus raphé magnus by the 5-HT1-receptor agonist naratriptan in rat
2001
GABAergic modulation of descending inhibitory systems from the rostral ventromedial medulla (RVM). Dose-response analysis of nociception and neurological deficits
2001
Descending control of pain
2002 Standout
Patient's assessment of outcome after three surgical procedures for the management of trigeminal neuralgia
1993
An ultra-sparse code underliesthe generation of neural sequences in a songbird
2002 StandoutNature
Complications of Preinjury Warfarin Use in the Trauma Patient
2003
Functional and chemical anatomy of the afferent vagal system
2000 Standout
Descending control of pain
1995
Direct and Indirect Activation of Cortical Neurons by Electrical Microstimulation
2006
A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability
1993 Standout
Long-term efficacy of microvascular decompression in trigeminal neuralgia
1988
Descending facilitatory modulation of a behavioral nociceptive response by stimulation in the adult rat anterior cingulate cortex
2000
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
The role of excitatory amino acid transmission within the rostral ventromedial medulla in the antinociceptive actions of systemically administered morphine
1999
Methods Used to Evaluate Pain Behaviors in Rodents
2017 Standout
Is serotonin hyperalgesic or analgesic?
2006
Electrical stimulation of neural tissue to evoke behavioral responses
1996
Delayed Intracranial Hemorrhage After Blunt Trauma: Are Patients on Preinjury Anticoagulants and Prescription Antiplatelet Agents at Risk?
2011
Vagal afferent modulation of nociception
1992
A possible interface between autonomic function and pain control: opioid analgesia and the nucleus tractus solitarius
1987
The efferent projections of the periaqueductal gray in the rat: A Phaseolus vulgaris‐leucoagglutinin study. II. Descending projections
1995
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
REVIEW ON CPP: Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade
2007 Standout
Impact of preinjury warfarin and antiplatelet agents on outcomes of trauma patients
2011
Microvascular decompression for trigeminal neuralgia: comments on a series of 250 cases, including 10 patients with multiple sclerosis
2000
Central sensitization: Implications for the diagnosis and treatment of pain
2010 Standout
Context, time, and memory retrieval in the interference paradigms of Pavlovian learning.
1993 Standout
Interference with GABA transmission in the rostral ventromedial medulla: Disinhibition of off-cells as a central mechanism in nociceptive modulation
1994
Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors
2006
Serotonergic, cholinergic and nociceptive inhibition or excitation of raphe magnus neurons in barbiturate-anesthetized rats
1993
Bi-directional changes in affective state elicited by manipulation of medullary pain-modulatory circuitry
2000
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
2007 Standout
Tonic Endovanilloid Facilitation of Glutamate Release in Brainstem Descending Antinociceptive Pathways
2007
Irritable bowel syndrome
2016 Standout
Neocortical efferent neurons with very slowly conducting axons: strategies for reliable antidromic identification
1998
The medullary dorsal reticular nucleus facilitates acute nociception in the rat
1996
Demonstration of neurovascular compression in trigeminal neuralgia with magnetic resonance imaging
1995
Animal models of pain: progress and challenges
2009
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Neurovascular compression in trigeminal neuralgia: a clinical and anatomical study
1992
Descending facilitatory control of mechanically evoked responses is enhanced in deep dorsal horn neurones following peripheral nerve injury
2004
Chronic back pain and rheumatoid arthritis: Predicting pain and disability from cognitive variables
1988
The behavioural importance of dynamically activated descending inhibition from the nucleus reticularis gigantocellularis pars alpha
2001
Modulation by serotonin of the neurons in rat nucleus raphe magnus in vitro
1993
Hyperalgesia during Naloxone-Precipitated Withdrawal from Morphine Is Associated with Increased On-Cell Activity in the Rostral Ventromedial Medulla
1990
An analgesia circuit activated by cannabinoids
1998 Nature
Preinjury warfarin, but not antiplatelet medications, increases mortality in elderly traumatic brain injury patients
2015
Patients' memories of painful medical treatments: real-time and retrospective evaluations of two minimally invasive procedures
1996 StandoutNobel
Comparison of the antinociceptive effect of morphine and glutamate at coincidental sites in the periaqueductal gray and medial medulla in rats
1989
Bad news from the brain: descending 5-HT pathways that control spinal pain processing
2004
Endocannabinoids in the Brainstem Modulate Dural Trigeminovascular Nociceptive Traffic via CB 1 and “Triptan” Receptors: Implications in Migraine
2013
Enkephalin neurons that project to the A7 catecholamine cell group are located in nuclei that modulate nociception: ventromedial medulla
1998
The Origin of Brainstem Noradrenergic and Serotonergic Projections to the Spinal Cord Dorsal Horn in the Rat
1992
The effect anticoagulation status on geriatric fall trauma patients
2016
Intrathecal coadministration of clonidine with serotonin receptor agonists produces supra-additive visceral antinociception in the rat
1991
Depletion of endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical and cooling stimuli induced by spinal nerve ligation
2006
Central mechanisms of pain modulation
1999
Management of Prehospital Antiplatelet and Anticoagulant Therapy in Traumatic Head Injury: A Review
2009
Pain measurement: an overview
1985 Standout
Characterization of descending inhibition and facilitation from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat
1990
The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition
2016 Standout
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Evaluation of microvascular decompression and partial sensory rhizotomy in 252 cases of trigeminal neuralgia
1989
The antinociception produced by microinjection of a cholinergic agonist in the ventromedial medulla is mediated by noradrenergic neurons in the A7 catecholamine cell group
1999
Impact of Hemorrhage on Trauma Outcome: An Overview of Epidemiology, Clinical Presentations, and Therapeutic Considerations
2006 Standout
Characterization of stimulation-produced analgesia from the nucleus tractus solitarius in the rat
1989
Risk of unfavorable long-term outcome in older adults with traumatic intracranial hemorrhage and anticoagulant or antiplatelet use
2013
The molecular logic of endocannabinoid signalling
2003 Standout
Trigeminal neuralgia: Pathology and pathogenesis
2001 Standout
Antinociception and modulation of rostral ventromedial medulla neuronal activity by local microinfusion of a cannabinoid receptor agonist
2004
Pharmacological evidence for a periaqueductal gray–nucleus raphe magnus connection mediating the antinociception induced by microinjecting carbachol into the dorsal periaqueductal gray of rats
1999
Functional activity mapping of the rat brainstem during formalin-induced noxious stimulation
1991
The formalin test: an evaluation of the method
1992 Standout
Effects of intravenous phenylephrine on blood pressure, nociception, and neural activity in the rostral ventral medulla in rats
1996
GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat
1987
Descending control of nociception: Specificity, recruitment and plasticity
2008
The costs of fatal and non-fatal falls among older adults
2006 Standout
The distribution of substance P-, enkephalin-and dynorphin-immunoreactive neurons in the medulla of the rat and their contribution to bulbospinal pathways
1987
Activation of brainstem N-methyl-D-aspartate receptors is required for the analgesic actions of morphine given systemically
2001
Neurotensin and pain modulation
2006
A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins
2017
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
2014 Standout
The biopsychosocial approach to chronic pain: Scientific advances and future directions.
2007 Standout
Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance
2003
Comparison of the Antinociceptive Effects Induced by Electroacupuncture and Transcutaneous Electrical Nerve Stimulation in the Rat
1992
AGA technical review on irritable bowel syndrome
2002 Standout
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
1988 Standout
Spinal and Supraspinal Mechanisms of Neuropathic Pain
2000
Diencephalic and brainstem mechanisms in migraine
2011
Brainstem modulation of pain during sleep and waking
2003
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
2014 Standout
Opioid-monoamine interactions in spinal antinociception: evidence for serotonin but not norepinephrine reciprocity
1988
A Comparison of Visceral and Somatic Pain Processing in the Human Brainstem Using Functional Magnetic Resonance Imaging
2005
A 5-HT1-type receptor mediates the antinociceptive effect of nucleus raphe magnus stimulation in the rat
1990
Chronic pain and medullary descending facilitation
2002
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Evaluation and management of geriatric trauma
2012
Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance
2004 StandoutNobel
Anatomy and physiology of a nociceptive modulatory system
1985
Cortico-NRM Influences on Trigeminal Neuronal Sensation
2008
An Opioidergic Cortical Antinociception Triggering Site in the Agranular Insular Cortex of the Rat that Contributes to Morphine Antinociception
1996
Hyperalgesia during acute opioid abstinence: evidence for a nociceptive facilitating function of the rostral ventromedial medulla
1991
Risk of Intracranial Hemorrhage in Ground‐level Fall With Antiplatelet or Anticoagulant Agents
2017
Analgesia produced by electrical stimulation of the brain
1984
Activation of Serotonergic Neurons in the Raphe Magnus Is Not Necessary for Morphine Analgesia
1998
Animal Models of Nociception
2001
A Role of TRPA1 in Mechanical Hyperalgesia is Revealed by Pharmacological Inhibition
2007 StandoutNobel
Microvascular Decompression and Partial Sensory Rhizotomy in the Treatment of Trigeminal Neuralgia
1992
Opioid actions on single nucleus raphe magnus neurons from rat and guinea‐pig in vitro.
1990
Circuitry Underlying AntiOpioid Actions of Orphanin FQ in the Rostral Ventromedial Medulla
1997
Medical Costs of Fatal and Nonfatal Falls in Older Adults
2018 Standout
Chapter 1 Anatomy and physiology of descending control of nociceptive responses of dorsal horn neurons: comprehensive review
1988
Estimating the global incidence of traumatic brain injury
2018 Standout
Repeat Head CT? Not Necessary for Patients with a Negative Initial Head CT on Anticoagulation or Antiplatelet Therapy Suffering Low-Altitude Falls
2017
Serotonergic Raphe Magnus Cells That Respond to Noxious Tail Heat Are Not on or off Cells
2000
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission
1986
Midbrain Periaqueductal Gray (PAG) Inhibits Nociceptive Inputs to Sacral Dorsal Horn Nociceptive Neurons Through α2-Adrenergic Receptors
1998
Physiological Properties of Raphe Magnus Neurons During Sleep and Waking
1999
Physiological Identification of Pontomedullary Serotonergic Neurons in the Rat
1997
Tonic Descending Facilitation from the Rostral Ventromedial Medulla Mediates Opioid-Induced Abnormal Pain and Antinociceptive Tolerance
2001
Noradrenergic input to nociceptive modulatory neurons in the rat rostral ventromedial medulla
1997
Sensory suppression during feeding
2005
Interactions between cardiovascular and pain regulatory systems
1984
Descending Pathways in Motor Control
2008 Standout
Supraspinal contributions to hyperalgesia
1999
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
The nuclei of origin of brainstem enkephalin and cholecystokinin projections to the spinal trigeminal nucleus of the rat
1987
Prothrombin Complex Concentrate Accelerates International Normalized Ratio Reversal and Diminishes the Extension of Intracranial Hemorrhage in Geriatric Trauma Patients
2014
Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in βArrestin-2 Knock-Out Mice
2002 StandoutNobel
Genetic contributions to generalized arousal of brain and behavior
2003 StandoutNobel
Morphine microinjected into the periaqueductal gray has differential effects on 3 classes of medullary neurons
1986
Neural Stimulation and Recording Electrodes
2008 Standout
Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry
1984 Standout
The measurement of clinical pain intensity: a comparison of six methods
1986 Standout
Relative contributions of the nucleus raphe magnus and adjacent medullary reticular formation to the inhibition by stimulation in the periaqueductal gray of a spinal nociceptive reflex in the pentobarbital-anesthetized rat
1984
Disorders of balance and vestibular function in US adults: data from the National Health and Nutrition Examination Survey, 2001-2004.
2009 Standout
Lesions of the periaqueductal gray and rostral ventromedial medulla disrupt antinociceptive but not cardiovascular aversive conditional responses
1994
Circuitry Underlying Antiopioid Actions of Cholecystokinin Within the Rostral Ventromedial Medulla
2001
Animal models of nociception.
2001
Dabigatran Use Does Not Increase Intracranial Hemorrhage in Traumatic Geriatric Falls When Compared with Warfarin
2015
Inhibition of Neuropathic Pain by Selective Ablation of Brainstem Medullary Cells Expressing the μ-Opioid Receptor
2001
Time-Dependent Descending Facilitation from the Rostral Ventromedial Medulla Maintains, But Does Not Initiate, Neuropathic Pain
2002
The organization of preoptic–medullary circuits in the male rat: evidence for interconnectivity of neural structures involved in reproductive behavior, antinociception and cardiovascular regulation
1999
Norepinephrine and serotonin-induced antinociception are blocked by naloxone with different dosages
1994
The Neural Basis of Decision Making
2007 Standout
Works of Greg Zorman being referenced
Traumatic Head Injury in the Anticoagulated Elderly Patient: A Lethal Combination
2001
The activity of neurons in the rostral medulla of the rat during withdrawal from noxious heat
1983
Naloxone-reversible analgesia produced by microstimulation in the rat medulla
1981
Evidence that disinhibition of brain stem neurones contributes to morphine analgesia
1983 Nature
Lumbar intrathecal naloxone blocks analgesia produced by microstimulation of the ventromedial medulla in the rat
1982
Physiology Evidence that disinhibition of brain stem neurones contributes to morphine analgesia
1985
Outcome following microsurgical vascular decompression or partial sensory rhizotomy in 125 cases of trigeminal neuralgia
1984
Relations among threshold, spike height, electrode distance, and conduction velocity in electrical stimulation of certain medullospinal neurons
1984
An estimate of minimum number of brain stem neurons required for inhibition of a flexion reflex
1984