Citation Impact
Citing Papers
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Suppression of Aging in Mice by the Hormone Klotho
2005 StandoutScience
Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling
2006
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
2009 StandoutScience
Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491
2005
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators
2016
Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle
2010
The Plasticity of Aging: Insights from Long-Lived Mutants
2005
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants
2007 StandoutNobel
Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock
2012
AMP-activated protein kinase: also regulated by ADP?
2011
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
mTOR Signaling in Growth Control and Disease
2012 Standout
Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans
2011
The C. elegans DAF-2 Insulin-Like Receptor is Abundantly Expressed in the Nervous System and Regulated by Nutritional Status
2011 StandoutNobel
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
The Caenorhabditis elegans Lifespan Machine
2013
Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress
2007
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
2013 StandoutNobel
The genetics of ageing
2010 StandoutNature
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
2009
Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction
2015
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans
2009
AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner
2014
Obesity and the regulation of fat metabolism
2007
Insulin/IGF-1 Receptor Signaling Enhances Biosynthetic Activity and Fat Mobilization in the Initial Phase of Starvation in Adult Male C. elegans
2011
C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
2009 StandoutNobel
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
Reprogramming aging and progeria
2012
Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
2008
A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans
2010
Mitochondrial longevity pathways
2010
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
2008 Nature
DNA Damage, Aging, and Cancer
2009 Standout
C. elegans dauer formation and the molecular basis of plasticity
2008
AMPK at the Nexus of Energetics and Aging
2014
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
2010
Autophagy in the Pathogenesis of Disease
2008 Standout
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks
2012 StandoutNobel
DAF-16/FOXO Regulates Transcription of cki-1/Cip/Kip and Repression of lin-4 during C. elegans L1 Arrest
2006
Autophagy and Aging
2011 Standout
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
2007 Standout
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
2009
An AMPK-FOXO Pathway Mediates Longevity Induced by a Novel Method of Dietary Restriction in C. elegans
2007
The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans
2008 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
2011 Standout
Geroscience: Linking Aging to Chronic Disease
2014 Standout
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
2010
The Hallmarks of Aging
2013 Standout
Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1
2013
Mitonuclear communication in homeostasis and stress
2016
The PI3K Pathway in Human Disease
2017 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB
2011 Nature
D-Glucosamine supplementation extends life span of nematodes and of ageing mice
2014
mTOR is a key modulator of ageing and age-related disease
2013 Nature
Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway
2013
Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans
2007
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
2008 Standout
Extending life span by increasing oxidative stress
2011
The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor
2007
AMPK as a Pro-longevity Target
2016
With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
2010
Adenosine Monophosphate-Activated Protein Kinase: A Central Regulator of Metabolism with Roles in Diabetes, Cancer, and Viral Infection
2011
AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling
2007
AMPK‐mediated formation of stress granules is required for dietary restriction‐induced longevity in Caenorhabditis elegans
2020
Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway
2017
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants
2019 StandoutNobel
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
Cell non-autonomous regulation of health and longevity
2020
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Adapting Proteostasis for Disease Intervention
2008 StandoutScience
Premature aging in mice activates a systemic metabolic response involving autophagy induction
2008
Insulin-Like Signaling, Nutrient Homeostasis, and Life Span
2007
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
2013 StandoutNobel
Resveratrol stimulates AMP kinase activity in neurons
2007
Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression inC. elegans
2012 StandoutNobel
Autophagy and Metabolism
2010 StandoutScience
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
2010 StandoutScience
New Genes Tied to Endocrine, Metabolic, and Dietary Regulation of Lifespan from a Caenorhabditis elegans Genomic RNAi Screen
2005
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction
2008
Works of Greg O’Connor being referenced
Aging networks in Caenorhabditis elegans: AMP‐activated protein kinase (aak‐2) links multiple aging and metabolism pathways
2006
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
2004