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Citing Papers
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
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De novo design of transmembrane β barrels
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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1
1996 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
1992 StandoutNature
Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis.
1993
Ras regulation of vascular endothelial growth factor and angiogenesis
2001
Stimulation by thyroid-stimulating hormone and Grave's immunoglobulin G of vascular endothelial growth factor mRNA expression in human thyroid follicles in vitro and flt mRNA expression in the rat thyroid in vivo.
1995
Transcriptional Regulation of Vascular Endothelial Growth Factor Gene Expression in Ovarian Bovine Granulosa Cells
1993
The fibroblast growth factor family: Structural and biological properties
1989
Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury
2007
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Vascular Permeability Factor/Vascular Endothelial Growth Factor and the Significance of Microvascular Hyperpermeability in Angiogenesis
1999
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
1995 StandoutNature
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Systems Biology of Vascular Endothelial Growth Factors
2008
VEGF mRNA is Reversibly Stabilized by Hypoxia and Persistently Stabilized in VEGF-Overexpressing Human Tumor Cell Lines
1995
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
1992 StandoutNature
Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.
1994
Vascular Endothelial Growth Factor Augments Muscle Blood Flow and Function in a Rabbit Model of Chronic Hindlimb Ischemia
1996
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
Keratinocyte-Derived Vascular Permeability Factor (Vascular Endothelial Growth Factor) Is a Potent Mitogen for Dermal Microvascular Endothelial Cells
1995
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
1992
VEGF Gene Delivery to Muscle
1998
Gene therapy for myocardial angiogenesis
1999
Neuropilin-2 and Neuropilin-1 Are Receptors for the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF) and of Placenta Growth Factor-2, but Only Neuropilin-2 Functions as a Receptor for the 145-Amino Acid Form of VEGF
2000
Regulators of Angiogenesis
1991
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
1993 Standout
The Carboxyl-terminal Domain(111–165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency
1996
Vascular permeability factor/vascular endothelial growth factor:A multifunctional angiogenic cytokine
1997
Vascular Endothelial Growth Factor: Molecular and Biological Aspects
1999
Vascular endothelial growth factor and its receptors
1996
The vascular endothelial growth factor family of polypeptides
1991
Human Melanoma Cells Secrete and Respond to Placenta Growth Factor and Vascular Endothelial Growth Factor
2000
A zonal organization of odorant receptor gene expression in the olfactory epithelium
1993 StandoutNobel
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
Vascular endothelial growth factor
1996
Overcoming Hysteresis to Attain Reversible Equilibrium Folding for Outer Membrane Phospholipase A in Phospholipid Bilayers
2011
Neuropilin-1 Is a Placenta Growth Factor-2 Receptor
1998
Transcriptional Regulation of the Rat Vascular Endothelial Growth Factor Gene by Hypoxia
1995
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Mechanisms of angiogenesis
1997 StandoutNature
Molecular Mechanisms of Developmental and Tumor Angiogenesis
1994
Cloning and characterization of a novel human gene related to vascular endothelial growth factor.
1996
Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues.
1992
Structure, Expression and Receptor-Binding Properties of Novel Vascular Endothelial Growth Factors
1999
Transgenic mouse models in angiogenesis and cardiovascular disease
2000
Conditioned Medium from Mouse Sarcoma 180 Cells Contains Vascular Endothelial Growth Factor
1990
Vascular permeability factor mRNA and protein expression in human kidney
1992
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
1996 StandoutNature
Determination of the subunit stoichiometry of a voltage-activated potassium channel
1991 StandoutNatureNobel
Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer
1995
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
2004 Standout
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
1996 StandoutNature
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor
1988
Placenta Growth Factor and Vascular Endothelial Growth Factor are Co-Expressed During Early Embryonic Development
1997
Identification of Vascular Endothelial Growth Factor Determinants for Binding KDR and FLT-1 Receptors
1996
Heterodimers of Placenta Growth Factor/Vascular Endothelial Growth Factor
1996
Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.
1993
VEGF: an update on biological and therapeutic aspects
2000
Detection of Vascular Endothelial Growth Factor Messenger RNA and Vascular Endothelial Growth Factor-like Activity in Proliferative Diabetic Retinopathy
1994
Structure, Expression and Receptor-Binding Properties of Placenta Growth Factor (PlGF)
1999
VEGFs, receptors and angiogenesis
1999
Expression of Vascular Endothelial Growth Factor and Placenta Growth Factor in Human Placenta1
1997
Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells.
1993
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
1993 StandoutNature
Arterial Gene Transfer for Therapeutic Angiogenesis in Patients with Peripheral Artery Disease. St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts
1996
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
Biological and biochemical properties of fibroblast growth factors. Implications for the pathogenesis of atherosclerosis.
1989
A systems approach to cancer therapy
1996
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
1998
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
The Fgf Family of Growth Factors and Oncogenes
1992
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.
1995 Standout
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
1997 StandoutScience
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus
1994
GROWTH CONE GUIDANCE: First Steps Towards a Deeper Understanding
1999
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.
1992
Local Delivery of Vascular Endothelial Growth Factor Accelerates Reendothelialization and Attenuates Intimal Hyperplasia in Balloon-Injured Rat Carotid Artery
1995
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
1998
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.
1993
Structural Characterization and Biological Functions of Fibroblast Growth Factor
1987
The Biology of Vascular Endothelial Growth Factor
1997 Standout
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.
1994
Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin.
1990
Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy
2002
flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors
1993
Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: Dose-response effect of basic fibroblast growth factor
1992
Bovine retina contains three growth factor activities with different affinity to heparin: eye derived growth factor I, II, III
1985
Induction of angiogenesis by bovine brain derived class 1 heparin-binding growth factor
1985
Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration.
1986
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor
1992 StandoutScience
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Neural Science
2000 StandoutNobel
Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth.
1993
Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus.
1990
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.
1994
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
Hypoxia induces vascular endothelial growth factor gene and protein expression in cultured rat islet cells.
1998
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
1989 StandoutScience
Novel Regulators of Bone Formation: Molecular Clones and Activities
1988 StandoutScience
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.
1993
Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas.
1993
Angiogenic Factors
1987 StandoutScience
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology.
1993
Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways.
1992
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Vascular endothelial growth factor B, a novel growth factor for endothelial cells.
1996
A unique family of endothelial cell polypeptide mitogens: the antigenic and receptor cross-reactivity of bovine endothelial cell growth factor, brain-derived acidic fibroblast growth factor, and eye-derived growth factor-II.
1985
Characterization of the receptor to vasculotropin on bovine adrenal cortex-derived capillary endothelial cells.
1990
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
An in vivo function for the transforming Myc protein: elicitation of the angiogenic phenotype.
2000
Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites.
1991
Regulation of angiogenesis via vascular endothelial growth factor receptors.
2000
Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
1992 Standout
Purification and characterization of heparin-binding endothelial cell growth factors.
1986
The Molecular Biology of Axon Guidance
1996 StandoutScience
Hypoxia Regulates Vascular Endothelial Growth Factor Gene Expression in Endothelial Cells
1995
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.
1995
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
1991 Standout
Cholinergic phenotype developed by noradrenergic sympathetic neurons after innervation of a novel cholinergic target in vivo
1988 Nature
Human basic fibroblast growth factor: nucleotide sequence and genomic organization.
1986
Vascular permeability factor gene expression in normal and neoplastic human ovaries.
1994
Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis
2004 Standout
Angiogenesis.
1992 Standout
Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.
1991
Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.
1985
Works of Greg Conn being referenced
Extracellular matrix heparan sulfate proteoglycans modulate the mitogenic capacity of acidic fibroblast growth factor
1989
Ion chromatographic quantification of cyanate in urea solutions: estimation of the efficiency of cyanate scavengers for use in recombinant protein manufacturing
2004
Hepatocyte Growth Factor Promotes Motor Neuron Survival and Synergizes with Ciliary Neurotrophic Factor
1997
Purification and Characterization of a Naturally Occurring Vascular Endothelial Growth Factor · Placenta Growth Factor Heterodimer
1995
Human brain-derived acidic and basic fibroblast growth factors: Amino terminal sequences and specific mitogenic activities
1986
Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.
1990
Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.
1990
The complete amino acid sequence of human brain-derived acidic fibroblast growth factor
1986
Isolated plasma membranes regulate neurotransmitter expression and facilitate effects of a soluble brain cholinergic factor.
1986
The isolation and purification of two anionic endothelial cell growth factors from human brain
1984