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Citing Papers
Yeast Pre-mRNA Splicing Requires a Pair of U1 snRNP-Associated Tetratricopeptide Repeat Proteins
1998
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
2002
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001
Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line
1998
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase
1997
Multiple Genes for Vacuolar-type ATPase Proteolipids inCaenorhabditis elegans
1998
Inflammation and cancer
2002 StandoutNature
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
The STAR protein, GLD-1, is a translational regulator of sexual identity in Caenorhabditis elegans
1999
An Olfactory Sensory Map in the Fly Brain
2000 StandoutNobel
A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
1998 StandoutNobel
Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites
1995
Isolation and characterisation of milk growth factor, a transforming‐growth‐factor‐β2‐related polypeptide, from bovine milk
1991
Regulatory T Cells
2000 StandoutNobel
Keratinocyte-Derived Granulocyte-Macrophage Colony Stimulating Factor Accelerates Wound Healing: Stimulation of Keratinocyte Proliferation, Granulation Tissue Formation, and Vascularization
2001
A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells
1994
Cloning and Expression of Glucocorticoid-induced Genes in Fetal Rat Lung Fibroblasts
1995
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon–intron structure of the gene
1998
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
GABAB-receptor subtypes assemble into functional heteromeric complexes
1998 Nature
Crystal structure of a model branchpoint–U2 snRNA duplex containing bulged adenosines
2001 StandoutNobel
Alpha-synuclein and transgenic mouse models
2004
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
Tumor Necrosis Factor-α Blockade: A Novel Therapy for Rheumatic Disease
2002
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens
1997
Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly
1999
Transforming Growth Factors β1, β2, and β3 and Their Receptors Are Differentially Regulated during Normal and Impaired Wound Healing
1996
Sleep Deprivation Effects on Circadian Clock Gene Expression in the Cerebral Cortex Parallel Electroencephalographic Differences among Mouse Strains
2008 StandoutNobel
Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis
1994
A specific quisqualate agonist inhibits kainate responses induced in Xenopus oocytes injected with rat brain RNA
1989
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Abnormal lung development and cleft palate in mice lacking TGF–β3 indicates defects of epithelial–mesenchymal interaction
1995 Standout
The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC
1997 StandoutNobel
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Genetic analysis of protein kinase B (AKT) in Drosophila
1998
Parkin Protects against the Toxicity Associated with Mutant α-Synuclein
2002
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
2001
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Value of genetic models in understanding the cause and mechanisms of Parkinson’s disease
2008
Structural and functional basis for GABAA receptor heterogeneity
1988 Nature
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Zinc has opposite effects on NMDA and Non-NMDA receptors expressed in xenopus oocytes
1990
ATP is a potent stimulator of the activation and formation of rodent osteoclasts
1998
Structure/function of α‐synuclein in health and disease: rational development of animal models for Parkinson's and related diseases
2002
Transforming growth factor βs and wound healing
1997
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequence
1998 StandoutNobel
Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
2001
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
Alpha-synuclein and neurodegenerative diseases
2001
Conservation of functional domains involved in RNA binding and protein–protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1
1998
Selective Insolubility of α-Synuclein in Human Lewy Body Diseases Is Recapitulated in a Transgenic Mouse Model
2001
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
A Schizosaccharomyces pombe gene encoding a novel polypeptide with a predicted α-helical rod structure found in the myosin and intermediate-filament families of proteins
1998
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
1992 StandoutNature
Imprinting of acetylcholine receptor messenger RNA accumulation in mammalian neuromuscular synapses
1990 StandoutNatureNobel
Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase
1996 StandoutNobel
Targeting programmed cell death in neurodegenerative diseases
2003
Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection
1999
Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase Promoter
2001
A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing
2000
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
The effects of ageing on wound healing: immunolocalisation of growth factors and their receptors in a murine incisional model
1997
Extracellular Nucleotides Activate non‐Selective Cation and Ca2+‐Dependent K+ Channels in Rat Osteoclasts
1997
Expression of P2 receptors in bone and cultured bone cells
2000
STAR, a gene family involved in signal transduction and activation of RNA
1997
Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease
2000
Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein
2002
Initial splice-site recognition and pairing during pre-mRNA splicing
1996
Parkinson's Disease
2003 Standout
The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
1993 StandoutNobel
Structure-Function Analysis of Qk1: a Lethal Point Mutation in Mouse quaking Prevents Homodimerization
1998
The use of Xenopus oocytes to probe synaptic communication
1988
Mechanism of activation of protein kinase B by insulin and IGF-1.
1996 Standout
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Receptors for Purines and Pyrimidines
1998 Standout
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
1998 StandoutScienceNobel
Neutralisation of TGF-β1 and TGF-β2 or exogenous addition of TGF-β3 to cutaneous rat wounds reduces scarring
1995
Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System
2002
Molecular characterization of two functional domains of CLIP-170 in vivo
1994
Molecular Physiology of P2X Receptors
2002 Standout
Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor.
1989
Self-Association of the Single-KH-Domain Family Members Sam68, GRP33, GLD-1, and Qk1: Role of the KH Domain
1997
Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the Gene
2003
In Vitro Genetic Analysis of the RNA Binding Site of Vigilin, a Multi-KH-Domain Protein
1998
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 StandoutScienceNobel
Extracellular ADP is a powerful osteolytic agent: evidence for signaling through the P2Y 1 receptor on bone cells
2001
Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors.
1996
Adenosine 5′-Triphosphate: a P2-Purinergic Agonist in the Myocardium
2001
Recognition of RNA Branch Point Sequences by the KH Domain of Splicing Factor 1 (Mammalian Branch Point Binding Protein) in a Splicing Factor Complex
2001 StandoutNobel
P2 purinergic receptors on osteoblasts and osteoclasts: Potential targets for drug development
2000
Molecular biology of the GABAA receptor: the receptor/channel superfamily
1987
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Expression and Modulation of Voltage-Gated Calcium Channels After RNA Injection in Xenopus Oocytes
1986 Science
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA.
1988
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Human neoplasms elicit multiple specific immune responses in the autologous host.
1995
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Isoforms of nitric oxide synthase
1995
Activity regulates the levels of acetylcholine receptor alpha-subunit mRNA in cultured chicken myotubes.
1985
Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity.
1987 StandoutNobel
P2X4 purinoceptors mediate an ATP-activated, non-selective cation current in rabbit osteoclasts
1999
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
2000
A Targeted Bypass Screen Identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for Stable U1 snRNP/Pre-mRNA Interaction
2009 StandoutNobel
The 3′-untranslated region of CaMKIIα is a cis-acting signal for the localization and translation of mRNA in dendrites
1996 StandoutNobel
Molecular Basis of Mechanotransduction in Living Cells
2001
WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: The proline glycine and methionine-rich motif
1998
A 5′ Splice Site-Proximal Enhancer Binds SF1 and Activates Exon Bridging of a Microexon
2000
FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands
1997
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Receptors for Purines and Pyrimidines
2012 Standout
Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response
1997
The Neuronal RNA Binding Protein Nova-1 Recognizes Specific RNA Targets In Vitro and In Vivo
1997
α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
2002
Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.
1991 Standout
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.
2002
Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase.
1995
Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing.
1995
The physiology of excitatory amino acids in the vertebrate central nervous system
1987 Standout
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance
1988 StandoutNatureNobel
Serological analysis of human tumor antigens: molecular definition and implications
1997
Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels
1986 StandoutNobel
Molecular biology of GABA A receptors
1990
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.
1993
Expression of a P2X7 Receptor by a Subpopulation of Human Osteoblasts
2001
The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain
2000
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Structural Insights into Group II Intron Catalysis and Branch-Site Selection
2002 StandoutScienceNobel
Spatial mechanisms of gene regulation in metazoan embryos
1991
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Molecular Dynamics Simulations of the Catalytic Pathway of a Cysteine Protease: A Combined QM/MM Study of Human Cathepsin K
2007
Works of Graeme Bilbe being referenced
P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption
1998
TGF‐βS and TGF‐β type II receptor in human epidermis: Differential expression in acute and chronic skin wounds
1993
Cloning of P2Y6 cDNAs and Identification of a Pseudogene: Comparison of P2Y Receptor Subtype Expression in Bone and Brain Tissues
1997
Developmental Regulation of Expression and Activity of Multiple Forms of the Drosophila RAC Protein Kinase
1995
Mouse models of α-synucleinopathy and Lewy pathology
2000
Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling
2001
Signaling in Human Osteoblasts by Extracellular Nucleotides
1999
Inducible nitric oxide synthase from human articular chondrocytes: cDNA cloning and analysis of mRNA expression
1994
Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine
2006
Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone
1995
P2Y receptor subtypes differentially couple to inwardly‐rectifying potassium channels
1998
Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA.
1996
Cloning and Tissue Distribution of Subunit C, D and E of the Human Vacuolar H+-ATPase
1993
GABA receptors induced in Xenopus oocytes by chick brain mRNA: evaluation of TBPS as a use-dependent channel-blocker
1987
Expression of functional GABA, glycine and glutamate receptors in Xenopus oocytes injected with rat brain mRNA
1984 Nature
Neuropathology in Mice Expressing Human α-Synuclein
2000
Molecular cloning and developmental expression of the catalytic and 65-kDa regulatory subunits of protein phosphatase 2A in Drosophila.
1992
Acetylcholine and GABA Receptors: Subunits of Central and Peripheral Receptors and Their Encoding Nucleic Acids
1983
Differential expression of TGF β1, β2 and β3 genes during mouse embryogenesis
1991
Neuropathology in mice expressing human alpha-synuclein
2000
Synthesis of functional chick brain GABA-benzodiazepine-barbiturate/receptor complexes in mRNA-injected Xenopus oocytes
1983
Restin: a novel intermediate filament-associated protein highly expressed in the Reed-Sternberg cells of Hodgkin's disease.
1992
Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae.
1995
Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts
1995