Citation Impact
Citing Papers
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
2014 Science
Loss of C9 ORF 72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death
2016
Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy
2015
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
2017
Indirect Regulation of Presenilins in CREB-mediated Transcription
2009
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
2018
Drosophila melanogaster as a model organism for Alzheimer’s disease
2013
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
2022 StandoutNobel
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons
2017 StandoutNobel
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression
2014
R loops: new modulators of genome dynamics and function
2015
Calcium signalling: dynamics, homeostasis and remodelling
2003 Standout
Signal integration by Ca2+ regulates intestinal stem-cell activity
2015 Nature
Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c
2016 StandoutNobel
Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
2014
Presenilin 1 Regulates Epidermal Growth Factor Receptor Turnover and Signaling in the Endosomal-Lysosomal Pathway
2007
The multidimensional mechanisms of long noncoding RNA function
2017 Standout
Ectopic Expression of Nolz-1 in Neural Progenitors Promotes Cell Cycle Exit/Premature Neuronal Differentiation Accompanying with Abnormal Apoptosis in the Developing Mouse Telencephalon
2013
The ins and outs of cellular Ca2+ transport
2011
Ageing as a risk factor for neurodegenerative disease
2019 Standout
mRNP granules
2014
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
2015
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
2016
Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration
2009 StandoutNobel
Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA
2015
Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
2015
Molecular physiology of the SERCA and SPCA pumps
2002
High-resolution AFM structure of DNA G-wires in aqueous solution
2018
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
2018 Standout
Bioavailability enhancers of herbal origin: An overview
2013 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Store-Operated Calcium Channels
2005 Standout
Nicastrin Is Required for γ-Secretase Cleavage of the Drosophila Notch Receptor
2002
SuFExable polymers with helical structures derived from thionyl tetrafluoride
2021 StandoutNobel
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization
2018
Amyotrophic lateral sclerosis
2017
Widespread Translational Remodeling during Human Neuronal Differentiation
2017 StandoutNobel
Artificial intelligence in drug development: present status and future prospects
2018 Standout
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
2019 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Molecular genetics of Ca2+ stores and intracellular Ca2+ signalling
2001
R-Loops as Cellular Regulators and Genomic Threats
2019
Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS
2014
G-quadruplex structures mark human regulatory chromatin
2016
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
2014
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
2020 Standout
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Signaling Mechanisms in Pattern-Triggered Immunity (PTI)
2015 Standout
Calcium in Plants
2003 Standout
Reading, writing and erasing mRNA methylation
2019 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Neurotherapeutic applications of nanoparticles in Alzheimer's disease
2010
The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
2017
Evidence That Assembly of an Active γ-Secretase Complex Occurs in the Early Compartments of the Secretory Pathway
2004
Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
2016
Breaking bad: R-loops and genome integrity
2015
Biomarker development for C9orf72 repeat expansion in ALS
2014
Development of Beta-Amyloid-induced Neurodegeneration in Alzheimer's Disease and Novel Neuroprotective Strategies
2005
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis
2017
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Redox Mechanisms in Neurodegeneration: From Disease Outcomes to Therapeutic Opportunities
2018
Phase to Phase with TDP-43
2017
An Endoplasmic Reticulum-Bound Ca2+/Mn2+Pump, ECA1, Supports Plant Growth and Confers Tolerance to Mn2+ Stress
2002
Processing of Notch and amyloid precursor protein by γ-secretase is spatially distinct
2004
Development of an Ion Mobility Quadrupole Time of Flight Mass Spectrometer
2008 StandoutNobel
HOW DO CROP PLANTS TOLERATE ACID SOILS? MECHANISMS OF ALUMINUM TOLERANCE AND PHOSPHOROUS EFFICIENCY
2004 Standout
The hydrodynamics of swimming microorganisms
2009 Standout
Protein Expression in a Drosophila Model of Parkinson's Disease
2006
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease
2016
2016
Biogenesis of γ-secretase early in the secretory pathway
2007 StandoutNobel
Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
2019 Standout
GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function
2015
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
2020 StandoutNobel
Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans
2014 StandoutNobel
2015
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Chlamydomonas flagella
2000
Works of Goran Periz being referenced
Functional reconstitution of γ‐secretase through coordinated expression of presenilin, nicastrin, Aph‐1, and Pen‐2
2004
TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling
2011
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
2014 Nature
Ca2+-ATPase function is required for intracellular trafficking of the Notch receptor in Drosophila
1999
RNA-Processing Protein TDP-43 Regulates FOXO-Dependent Protein Quality Control in Stress Response
2014
DNA Elements Regulating Α1-Tubulin Gene Induction during Regeneration of Eukaryotic Flagella
1997
Nolz1 is induced by retinoid signals and controls motoneuron subtype identity through distinct repressor activities
2008