Standout Papers
- Cellular cofactors affecting hepatitis C virus infection and replication (2007)
- CD81 Is Required for Hepatitis C Virus Glycoprotein-Mediated Viral Infection (2004)
- Identification of microRNAs of the herpesvirus family (2005)
- Interfering with hepatitis C virus RNA replication (2004)
- Silencing of USP18 Potentiates the Antiviral Activity of Interferon Against Hepatitis C Virus Infection (2006)
- Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs (2002)
Citation Impact
Citing Papers
Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection
2009 Science
Robust hepatitis C virus infection in vitro
2005
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Superinfection Exclusion in Cells Infected with Hepatitis C Virus
2007 StandoutNobel
Masking the 5′ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex
2011
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Flavivirus Replication Complex Assembly Revealed by DNAJC14 Functional Mapping
2012 StandoutNobel
Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus andHost
2006
Affinity Capture and Identification of Host Cell Factors Associated with Hepatitis C Virus (+) Strand Subgenomic RNA
2013
Identification and Targeting of an Interaction between a Tyrosine Motif within Hepatitis C Virus Core Protein and AP2M1 Essential for Viral Assembly
2012
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
2011 Standout
Challenges and successes in developing new therapies for hepatitis C
2005 Nature
Early steps of the hepatitis C virus life cycle
2008
Cell Culture Systems for Hepatitis C Virus
2013
Hepatitis C virus entry into host cells
2007
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Autophagy and Viruses: Adversaries or Allies?
2013 Standout
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Regulation of microRNA biogenesis
2014 Standout
Epigallocatechin-3-Gallate (EGCG), a Green Tea Polyphenol, Stimulates Hepatic Autophagy and Lipid Clearance
2014
Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo
2008
LNA-mediated microRNA silencing in non-human primates
2008 Nature
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Tomato bushy stunt virus Co-Opts the RNA-Binding Function of a Host Metabolic Enzyme for Viral Genomic RNA Synthesis
2008
High Density Lipoproteins Facilitate Hepatitis C Virus Entry through the Scavenger Receptor Class B Type I
2005
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Hepatitis C virus comes full circle
2005
Hepatitis C Virus Is Primed by CD81 Protein for Low pH-dependent Fusion
2011
Genetic variation in microRNA networks: the implications for cancer research
2010
Hepatitis C Virus RNA Replication
2013
Identification of the Niemann-Pick C1–like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor
2012
Hepatitis C virus entry: Molecular biology and clinical implications
2006
Cell entry of hepatitis C virus
2006
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila
2007 Standout
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Hepatitis C virus and microRNAs: miRed in a host of possibilities
2014
Mature and functional viral miRNAs transcribed from novel RNA polymerase III promoters
2009
Hepatitis C Virus Proteins: From Structure to Function
2013
RNA interference against viruses: strike and counterstrike
2007
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases
2005
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
A Mammalian Herpesvirus Uses Noncanonical Expression and Processing Mechanisms to Generate Viral MicroRNAs
2010
Metazoan MicroRNAs
2018 Standout
Chapter 2 Cutting the Gordian Knot-Development and Biological Relevance of Hepatitis C Virus Cell Culture Systems
2008
High Density Lipoprotein Inhibits Hepatitis C Virus-neutralizing Antibodies by Stimulating Cell Entry via Activation of the Scavenger Receptor BI
2006
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
A novel class of small RNAs bind to MILI protein in mouse testes
2006 Nature
Claudin Association with CD81 Defines Hepatitis C Virus Entry
2010
miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components
2011
Dual regulation of hepatitis C viral RNA by cellular RNAi requires partitioning of Ago2 to lipid droplets and P-bodies
2011
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein
2008
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Viruses and microRNAs
2006
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
2008
Temporal Analysis of Hepatitis C Virus Cell Entry with Occludin Directed Blocking Antibodies
2013
A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
2010 Nature
Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells
2006 StandoutNobel
Characterization of host‐range and cell entry properties of the major genotypes and subtypes of hepatitis C virus†
2005
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Unambiguous Identification of miRNA:Target Site Interactions by Different Types of Ligation Reactions
2014
Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains
2009
Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
2007 StandoutNobel
Hepatitis C Virus Entry
2007 StandoutNobel
Virion Assembly and Release
2013
Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity
2012
Hepatitis C virus E2 links soluble human CD81 and SR-B1 protein
2006
Revealing the world of RNA interference
2004 StandoutNatureNobel
Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants
2011
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Hepatitis C Virus RNA Translation
2013
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Hepatitis C virus entry into hepatocytes: Molecular mechanisms and targets for antiviral therapies
2010
Hepatitis C Virus Glycoproteins Mediate Low pH-dependent Membrane Fusion with Liposomes
2005
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
Hepatitis C Virus Glycoprotein E2 Contains a Membrane-proximal Heptad Repeat Sequence That Is Essential for E1E2 Glycoprotein Heterodimerization and Viral Entry
2004
Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome
2008
Interferon modulation of cellular microRNAs as an antiviral mechanism
2007 Nature
Degradation of Cellular miR-27 by a Novel, Highly Abundant Viral Transcript Is Important for Efficient Virus Replication In Vivo
2012
Avoiding the void: cell-to-cell spread of human viruses
2008
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
Heme is involved in microRNA processing
2006
Functional hepatitis C virus envelope glycoproteins
2004
Innate Immune Responses to Hepatitis C Virus
2013 StandoutNobel
Determinants of CD81 dimerization and interaction with hepatitis C virus glycoprotein E2
2005
Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication
2012
A Primate Herpesvirus Uses the Integrator Complex to Generate Viral MicroRNAs
2011
Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly
2008
Inference of miRNA targets using evolutionary conservation and pathway analysis
2007
Replication of hepatitis C virus
2007 StandoutNobel
Reciprocal Inhibition between Intracellular Antiviral Signaling and the RNAi Machinery in Mammalian Cells
2013
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Scavenger Receptor Class B Type I and Hepatitis C Virus Infection of PrimaryTupaiaHepatocytes
2005
Phosphoinositides in the Hepatitis C Virus Life Cycle
2012
Hepatitis C Virus Egress and Release Depend on Endosomal Trafficking of Core Protein
2010
Novel Function of CD81 in Controlling Hepatitis C Virus Replication
2010
Ago HITS-CLIP Expands Understanding of Kaposi's Sarcoma-associated Herpesvirus miRNA Function in Primary Effusion Lymphomas
2012
Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122
2010
Hepatitis C Virus Co-Opts Ras-GTPase-Activating Protein-Binding Protein 1 for Its Genome Replication
2011 StandoutNobel
Role of Annexin A2 in the Production of Infectious Hepatitis C Virus Particles
2010
Scavenger Receptor BI and BII Expression Levels Modulate Hepatitis C Virus Infectivity
2007
L-SIGN (CD209L) and DC-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus
2004
The evolution of RNAi as a defence against viruses and transposable elements
2008
Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus
2007
Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity
2008
Hepatitis C virus cell entry: role of lipoproteins and cellular receptors
2009
La Autoantigen Is Necessary for Optimal Function of the Poliovirus and Hepatitis C Virus Internal Ribosome Entry Site In Vivo and In Vitro
2004
An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies
2005
Diverse Hepatitis C Virus Glycoproteins Mediate Viral Infection in a CD81-Dependent Manner
2004 StandoutNobel
Antiviral Stilbene 1,2-Diamines Prevent Initiation of Hepatitis C Virus RNA Replication at the Outset of Infection
2011 StandoutNobel
High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein
2007 StandoutNobel
Identification of transferrin receptor 1 as a hepatitis C virus entry factor
2013
Initiation of Hepatitis C Virus Infection Is Dependent on Cholesterol and Cooperativity between CD81 and Scavenger Receptor B Type I
2006
Structural bias in T4 RNA ligase-mediated 3′-adapter ligation
2012
Functional Analysis of Hepatitis C Virus Envelope Proteins, Using a Cell-Cell Fusion Assay
2006
Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs
2007 Science
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Hepatitis C virus entry: potential receptors and their biological functions
2006
Characterization of Infectious Retroviral Pseudotype Particles Bearing Hepatitis C Virus Glycoproteins
2004 StandoutNobel
Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells
2007
Cell-type-specific signatures of microRNAs on target mRNA expression
2006
Impact of Intra- and Interspecies Variation of Occludin on Its Function as Coreceptor for Authentic Hepatitis C Virus Particles
2011
MicroRNA-122 antagonism against hepatitis C virus genotypes 1–6 and reduced efficacy by host RNA insertion or mutations in the HCV 5′ UTR
2011
Regulation of Hepatitis C Virus Replication by Nuclear Translocation of Nonstructural 5A Protein and Transcriptional Activation of Host Genes
2013
Entry of hepatitis C virus pseudotypes into primary human hepatocytes by clathrin-dependent endocytosis
2006
A Conserved Gly436-Trp-Leu-Ala-Gly-Leu-Phe-Tyr Motif in Hepatitis C Virus Glycoprotein E2 Is a Determinant of CD81 Binding and Viral Entry
2006
Mathematical Modeling of Subgenomic Hepatitis C Virus Replication in Huh-7 Cells
2006 StandoutNobel
Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses
2006
Robust Production of Infectious Hepatitis C Virus (HCV) from Stably HCV cDNA-Transfected Human Hepatoma Cells
2005
Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry
2006 StandoutNobel
Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis
2012
Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication
2012
Human Ago2 Is Required for Efficient MicroRNA 122 Regulation of Hepatitis C Virus RNA Accumulation and Translation
2010
Evaluation of Phosphatidylinositol-4-Kinase IIIα as a Hepatitis C Virus Drug Target
2012
Genetic and Functional Characterization of the N-Terminal Region of the Hepatitis C Virus NS2 Protein
2013 StandoutNobel
Diverse CD81 Proteins Support Hepatitis C Virus Infection
2006 StandoutNobel
Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Glycoproteins
2005
Towards a small animal model for hepatitis C
2009 StandoutNobel
Different Domains of CD81 Mediate Distinct Stages of Hepatitis C Virus Pseudoparticle Entry
2006
Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment
2017 StandoutNobel
Ultrastructural and Biophysical Characterization of Hepatitis C Virus Particles Produced in Cell Culture
2010
Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding
2006
The Level of CD81 Cell Surface Expression Is a Key Determinant for Productive Entry of Hepatitis C Virus into Host Cells
2006
Photothermal Nanomaterials: A Powerful Light-to-Heat Converter
2023 Standout
Stabilization of hepatitis C virus RNA by an Ago2–miR-122 complex
2012
Different Requirements for Scavenger Receptor Class B Type I in Hepatitis C Virus Cell-Free versus Cell-to-Cell Transmission
2013 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants
2009 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Glenn Randall being referenced
Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication
2009
Hepatitis C virus—host interactions, replication, and viral assembly
2012
Molecular Determinants and Dynamics of Hepatitis C Virus Secretion
2012
Multifaceted roles for lipids in viral infection
2011
Functions of autophagy in normal and diseased liver
2013
Potential roles for cellular cofactors in hepatitis C virus replication complex formation
2009
Hepatitis C virus cell culture replication systems: their potential use for the development of antiviral therapies
2001
Silencing of USP18 Potentiates the Antiviral Activity of Interferon Against Hepatitis C Virus Infection
2006 StandoutNobel
RNA Interference and Single Particle Tracking Analysis of Hepatitis C Virus Endocytosis
2009
Allele-Specific Targeting of microRNAs to HLA-G and Risk of Asthma
2007
Manipulation or capitulation: virus interactions with autophagy
2011
Dengue Virus-Induced Autophagy Regulates Lipid Metabolism
2010
Identification of microRNAs of the herpesvirus family
2005 StandoutNobel
Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication
2011
CD81 Is Required for Hepatitis C Virus Glycoprotein-Mediated Viral Infection
2004 StandoutNobel
Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis
2010
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
A Multifunctional Neutralizing Antibody‐Conjugated Nanoparticle Inhibits and Inactivates SARS‐CoV‐2
2021
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel