Citation Impact
Citing Papers
Hydroxyurea therapy lowers transcranial Doppler flow velocities in children with sickle cell anemia
2007
The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)
2009
Signal integration in the endoplasmic reticulum unfolded protein response
2007 Standout
Fetal Hemoglobin, Sickling, and Sickle Cell Disease
1990
A unified mixed-model method for association mapping that accounts for multiple levels of relatedness
2005 Standout
Silent Cerebral Infarcts in Sickle Cell Anemia: A Risk Factor Analysis
1999
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1997 Standout
The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin
2005 Standout
Inflammation and metabolic disorders
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Pain in Sickle Cell Disease
1991
Inflammatory links between obesity and metabolic disease
2011 Standout
Pathogenesis and Treatment of Sickle Cell Disease
1997
Human red cell Aquaporin CHIP. II. Expression during normal fetal development and in a novel form of congenital dyserythropoietic anemia.
1994 StandoutNobel
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Ion Transport Pathology in the Mechanism of Sickle Cell Dehydration
2004
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
The β-Thalassemias
1999 Standout
Huntington's disease
2007 Standout
Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia
1995 Standout
Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene
1996 Nature
Hepatitis C virus NS5A as a potential viral Bcl‐2 homologue interacts with Bax and inhibits apoptosis in hepatocellular carcinoma
2003
JUVENILE CHRONIC MYELOGENOUS LEUKAEMIA: THE ONLY EXAMPLE OF TRULY FETAL (NOT FETAL‐LIKE) ERYTHROPOIESIS
1990
Cellular effects of hydroxyurea in Hb SC disease
1997
Hydroxyurea Therapy for Pediatric Patients With Hemoglobin SC Disease
2001
Fetal Hemoglobin in Sickle Cell Anemia: Determinants of Response to Hydroxyurea
1997
Treatment of Obesity with Celastrol
2015 Standout
The muscular dystrophies
2002 Standout
When Checkpoints Fail
1997 StandoutNobel
Histone deacetylases, transcriptional control, and cancer
2000
Modifier genes and sickle cell anemia
2006
Phenotype—genotype relationships in monogenic disease: lessons from the thalassaemias
2001
Phase 1 Study of the E-Selectin Inhibitor GMI 1070 in Patients with Sickle Cell Anemia
2014
Cystic Fibrosis: A Disease of Altered Protein Folding
1997
Gender and haplotype effects upon hematological manifestations of adult sickle cell anemia
1995
Sickle-cell disease
1997
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
2007 Standout
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
2013 StandoutNobel
Principal components analysis corrects for stratification in genome-wide association studies
2006 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Advances in clinical research in sickle cell disease
2008
Prevention of secondary stroke and resolution of transfusional iron overload in children with sickle cell anemia using hydroxyurea and phlebotomy
2004
Investigational drugs in sickle cell anemia
2009
A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger
2008
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload
2001 Standout
Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography
1998 Standout
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Effect of hydroxyurea on the rheological properties of sickle erythrocytes in vivo
1989
DNA Methylation Inhibitors in the Treatment of Leukemias, Myelodysplastic Syndromes and Hemoglobinopathies: Clinical Results and Possible Mechanisms of Action
2000
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
Levels of Fetal Hemoglobin Necessary for Treatment of Sickle Cell Disease
1988
Sickle cell disease: no longer a single gene disorder
2001
Sickle-cell disease
2010 Standout
Identification of the haemoglobin scavenger receptor
2001 StandoutNature
Activation of ion transport pathways by changes in cell volume
1991
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
1995 Standout
Hydroxyurea therapy in children severely affected with sickle cell disease
1996
Neuroprotective Effects of Phenylbutyrate in the N171-82Q Transgenic Mouse Model of Huntington's Disease
2004
Clinical and hematologic effects of hydroxyurea in children with sickle cell anemia
1996
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death
1994 Standout
Stroke risk in siblings with sickle cell anemia
2003
Therapeutic Strategies for Prevention of Sickle Cell Dehydration
2001
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland
2000 Standout
Disorders of Iron Metabolism
1999 Standout
Long-term hydroxyurea treatment in young sickle cell patients
1999
Treatment of Sickle Cell Anemia with Hydroxyurea and Erythropoietin
1990
A genetic interaction between the vesicular acetylcholine transporter VAChT/UNC-17 and synaptobrevin/SNB-1 in C. elegans
2006 StandoutNobel
Red cell indices in classification and treatment of anemias
2013
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
2001 StandoutNobel
Pharmacologic Modulation of Fetal Hemoglobin
2001
Pathophysiology and treatment of stroke in sickle-cell disease: present and future
2006
Extended Therapy with Intravenous Arginine Butyrate in Patients with β-Hemoglobinopathies
1995
A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis
2020 StandoutNobel
Decrease of Very Late Activation Antigen-4 and CD36 on Reticulocytes in Sickle Cell Patients Treated With Hydroxyurea
1997
Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy
2002
5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.
1982
Association of TNF2, a TNF-α Promoter Polymorphism, With Septic Shock Susceptibility and Mortality
1999 Standout
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
Expression of embryonic globins by erythroid cells in juvenile chronic myelocytic leukemia
1991
Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia
2002
A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy
1996
A cautionary note regarding hydroxyurea in sickle cell disease
1994
Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis
2013
Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase
1997
Divergent Nitric Oxide Bioavailability in Men and Women With Sickle Cell Disease
2003
On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC
1989
Half-lives of beta and gamma globin messenger RNAs and of protein synthetic capacity in cultured human reticulocytes
1985
Fetal hemoglobin in sickle cell anemia: relationship to erythrocyte adhesion markers and adhesion
2001
Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex.
1983
Individual Variation in the Production and Survival of F Cells in Sickle-Cell Disease
1978
Hydroxyurea as an Alternative to Blood Transfusions for the Prevention of Recurrent Stroke in Children With Sickle Cell Disease
1999
Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease.
1999
Adapting Proteostasis for Disease Intervention
2008 StandoutScience
High-Dose Intravenous Methylprednisolone Therapy for Pain in Children and Adolescents with Sickle Cell Disease
1994
Transgenic sickle mice have vascular inflammation
2003
Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities
2011
The Future of Genetic Studies of Complex Human Diseases
1996 StandoutScience
Genetic Dissection of Complex Traits
1994 StandoutScience
Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.
1984
Erythrocyte Enzymopathies in the Newborn
1981
Hydroxyurea for treatment of severe sickle cell anemia: a pediatric clinical trial
1996
Iron-Deficiency Anemia
2015 Standout
Induction of human γ globin gene expression by histone deacetylase inhibitors
2003
CpG-rich islands and the function of DNA methylation
1986 StandoutNature
Hydroxyurea affects cell morphology, cation transport, and red blood cell adhesion in cultured vascular endothelial cells
1994
Correction of a human beta S-globin gene by gene targeting.
1991 StandoutNobel
Hydroxyurea corrects the dysregulated L-selectin expression and increased H2O2 production of polymorphonuclear neutrophils from patients with sickle cell anemia
2002
Transfusion management of sickle cell disease
1993
Glucose-6-phosphate dehydrogenase deficiency
2008 Standout
Sparing effect of hemoglobin F and hemoglobin A2 on the polymerization of hemoglobin S at physiologic ligand saturations.
1993
Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
1996 StandoutScience
Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes
2006 StandoutScience
Systematic Review: Hydroxyurea for the Treatment of Adults with Sickle Cell Disease
2008
Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group.
1999
Phosphatidylserine externalization in sickle red blood cells: associations with cell age, density, and hemoglobin F
2003
Impaired cell volume regulation in intestinal crypt epithelia of cystic fibrosis mice.
1995 StandoutNobel
Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease
2003
Mechanism of action of hydroxyurea.
1992
Factors affecting prepubertal growth in homozygous sickle cell disease.
1996
Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene.
1983 StandoutNobel
Works of GJ Dover being referenced
Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production
1986
Microscopic method for assaying F cell production: illustrative changes during infancy and in aplastic anemia
1978
Selective hemolysis of adult red blood cells: an aid to prenatal diagnosis of hemoglobinopathies
1979
5-Azacytidine increases HbF production and reduces anemia in sickle cell disease: dose-response analysis of subcutaneous and oral dosage regimens
1985
Fetal hemoglobin-containing cells have the same mean corpuscular hemoglobin as cells without fetal hemoglobin: a reciprocal relationship between gamma- and beta-globin gene expression in normal subjects and in those with high fetal hemoglobin production
1987
Fetal hemoglobin production in cultures of primitive and mature human erythroid progenitors: differentiation affects the quantity of fetal hemoglobin produced per fetal-hemoglobin-containing cell
1983
Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate
1994
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]
1992
Increasing fetal hemoglobin production in sickle cell disease: results of clinical trials.
1987
Fetal hemoglobin-containing cells have the same mean corpuscular hemoglobin as cells without fetal hemoglobin: a reciprocal relationship between gamma- and beta-globin gene expression in normal subjects and in those with high fetal hemoglobin production
1987
Effects of hydroxyurea on hemoglobin F and water content in the red blood cells of dogs and of patients with sickle cell anemia
1991
Effects of hydroxyurea on hemoglobin F and water content in the red blood cells of dogs and of patients with sickle cell anemia
1991
Hydroxyurea-induced augmentation of fetal hemoglobin production in patients with sickle cell anemia
1987
Fetal hemoglobin synthesis in erythroid cultures in hereditary persistence of fetal hemoglobin and beta o-thalassemia
1984
Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production
1986
Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate
1994
Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial
1995
Hydroxyurea-induced augmentation of fetal hemoglobin production in patients with sickle cell anemia
1987
Quantitation of hemoglobins within individual red cells: asynchronous biosynthesis of fetal and adult hemoglobin during erythroid maturation in normal subjects
1980
Production of F cells in sickle cell anemia: regulation by a genetic locus or loci separate from the beta-globin gene cluster
1984
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]
1992
Quantitation of hemoglobins within individual red cells: asynchronous biosynthesis of fetal and adult hemoglobin during erythroid maturation in normal subjects
1980
Selective hemolysis of adult red blood cells: an aid to prenatal diagnosis of hemoglobinopathies
1979
Changing erythrocyte populations in juvenile chronic myelocytic leukemia: evidence for disordered regulation
1977
Fetal hemoglobin production in cultures of primitive and mature human erythroid progenitors: differentiation affects the quantity of fetal hemoglobin produced per fetal-hemoglobin-containing cell
1983
Fetal hemoglobin levels in sickle cell disease and normal individuals are partially controlled by an X-linked gene located at Xp22.2
1992
Stimulation of fetal hemoglobin production by hydroxyurea in sickle cell anemia.
1989
An analysis of fetal hemoglobin variation in sickle cell disease: the relative contributions of the X-linked factor, beta-globin haplotypes, alpha-globin gene number, gender, and age
1995
Fetal hemoglobin levels in sickle cell disease and normal individuals are partially controlled by an X-linked gene located at Xp22.2
1992
Microscopic method for assaying F cell production: illustrative changes during infancy and in aplastic anemia
1978