Citation Impact
Citing Papers
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Mitotic and mitogenic Wnt signalling
2012
Sex hormone modulation of cell growth and apoptosis of the human monocytic/macrophage cell line
2005
Stress, sex hormones, inflammation, and major depressive disorder: Extending Social Signal Transduction Theory of Depression to account for sex differences in mood disorders
2019
Luminescent imaging of β-galactosidase activity in living subjects using sequential reporter-enzyme luminescence
2006
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
MYC on the Path to Cancer
2012 Standout
Temporal expression of IL-1β protein and mRNA in the brain after systemic LPS injection is affected by age and estrogen
2006
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
Enhancement of Estrogen Receptor Transcriptional Activity by the Coactivator GRIP-1 Highlights the Role of Activation Function 2 in Determining Estrogen Receptor Pharmacology
1998
Estrogen attenuates tumor necrosis factor-α expression to provide ischemic neuroprotection in female rats
2002
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Chronic inflammation in the etiology of disease across the life span
2019 Standout
17β-Estradiol Enhances the Production of Nerve Growth Factor in THP-1-Derived Macrophages or Peripheral Blood Monocyte-Derived Macrophages
2003
Central Oxytocin Mediates Stress‐Induced Tachycardia
1995
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma
2000
17β-Estradiol- and Lipopolysaccharide-Induced Changes in Nitric Oxide, Tumor Necrosis Factor-α and Vascular Endothelial Growth Factor Release from RAW 264.7 Macrophages
2003
Alzheimer's disease
2011 Standout
Estrogen receptor α is a major mediator of 17β-estradiol’s atheroprotective effects on lesion size in Apoe–/– mice
2001 StandoutNobel
Endometriosis
2009 Standout
Progress in Antisense Oligonucleotide Therapeutics
1996
Potentiation of Human Estrogen Receptor α Transcriptional Activation through Phosphorylation of Serines 104 and 106 by the Cyclin A-CDK2 Complex
1999
The Protective Effects of Estrogen on the Cardiovascular System
1999 Standout
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
1994
Sexual dimorphism in expression of receptors for bacterial lipopolysaccharides in murine macrophages: A possible mechanism for gender-based differences in endotoxic shock susceptibility
2006
Novel Mechanisms of Estrogen Action in the Brain: New Players in an Old Story
1999
Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters
2001
Estrogen Regulates Neurofilament Gene Expression in Adult Female Rat Dorsal Root Ganglion Neurons
1997
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
The anti‐inflammatory activity of estrogen in glial cells is regulated by the PKC‐anchoring protein RACK‐1
2002
Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis
2008
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1998 Standout
Estrogen and brain inflammation: Effects on microglial expression of MHC, costimulatory molecules and cytokines
2005
Differential effects of estrogen in the injured forebrain of young adult and reproductive senescent animals
2003
Genetic Animal Models of Alcohol and Drug Abuse
1994 Science
Estrogen receptor-α and -β immunoreactivity and mRNA in neurons of sensory and autonomic ganglia and spinal cord
2001
Stress and the brain: from adaptation to disease
2005 Standout
Estrogen Receptors in Human Nontarget Tissues: Biological and Clinical Implications*
1995
Long-term estrogen therapy worsens the behavioral and neuropathological consequences of chronic brain inflammation.
2002
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
Convergent Pathways for Steroid Hormone- and Neurotransmitter-Induced Rat Sexual Behavior
1994 Science
Sex differences in autoimmune diseases
2011
17β-Estradiol and the phytoestrogen genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin
2002
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
Alzheimer's disease
2016 Standout
The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen
1998 Standout
Cancer-epigenetics comes of age
1999 Standout
Neurotransmitters activate the human estrogen receptor in a neuroblastoma cell line
1997
Estrogen Modulates Neuronal Bcl‐xl Expression and β‐Amyloid‐Induced Apoptosis
1999
A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer
2004 Standout
A selective estrogen receptor-β agonist causes lesion regression in an experimentally induced model of endometriosis
2004
Distributions of estrogen receptors alpha and beta in sympathetic neurons of female rats: Enriched expression by uterine innervation
2002
The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator
2002 Standout
Insulators: many functions, many mechanisms
2002
Down regulation of interleukin-1β-induced nitric oxide production in lacrimal gland acinar cells by sex steroids
2004
Molecular basis of agonism and antagonism in the oestrogen receptor
1997 StandoutNature
Sex differences in Parkinson’s disease: Features on clinical symptoms, treatment outcome, sexual hormones and genetics
2017
Endometriosis
2004 Standout
Ligand-independent activation of steroid hormone receptors
1998
Recapitulation and Design of Protein Binding Peptide Structures and Sequences
2006 StandoutNobel
Sex differences in immune responses
2016 Standout
Soluble glucocorticoid‐induced tumor necrosis factor receptor (sGITR) increased MMP‐9 activity in murine macrophage
2003
Steroid hormone receptors: Many Actors in search of a plot
1995 Standout
Estrogen Modulates Microglial Inflammatory Mediator Production via Interactions with Estrogen Receptor β
2004
Production and Actions of Estrogens
2002 Standout
Effect of 17β-estradiol on tumor necrosis factor-α-induced cytotoxicity in the human peripheral T lymphocytes
2005
Estrogen regulates cytokine production and apoptosis in PMA‐differentiated, macrophage‐like U937 cells
2003
Estrogen Plus Progestin and the Incidence of Dementia and Mild Cognitive Impairment in Postmenopausal Women
2003 Standout
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
1995 StandoutNature
The Endogenous Estrogen Status Regulates Microglia Reactivity in Animal Models of Neuroinflammation
2006
The fundamental role of epigenetic events in cancer
2002 Standout
Sex hormones and the immune response in humans
2005
Antisense oligonucleotide strategies in neuropharmacology
1994
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
CTCF: Master Weaver of the Genome
2009 Standout
The Complex Role of Estrogens in Inflammation
2007 Standout
Estrogen suppresses IL-1β-mediated induction of COX-2 pathway in rat cerebral blood vessels
2004
The Protective Role of Endogenous Estrogens in Carrageenan-Induced Lung Injury in the Rat
2001
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Estrogen pretreatment protects males against hypoxia-induced immune depression
2002
17β-Estradiol Inhibits Inflammatory Gene Expression by Controlling NF-κB Intracellular Localization
2005
Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia
1997 Standout
Quantitative Analysis of Estrogen Receptor Proteins in Rat Mammary Gland*
2001
The estrogen receptor CpG island is methylated in most hematopoietic neoplasms.
1996
Estrogen receptor-α mediates the brain antiinflammatory activity of estradiol
2003
The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1
1999
MYCN-regulated microRNAs repress estrogen receptor-α ( ESR1 ) expression and neuronal differentiation in human neuroblastoma
2010
Characterization of Transiently and Constitutively Expressed Progesterone Receptors: Evidence for Two Functional States
2000
Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor.
1996
Selective Progesterone Receptor Modulator Development and Use in the Treatment of Leiomyomata and Endometriosis
2005
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
Ligand-independent Activation of Steroid Receptors: New Roles for Old Players
1999
Mechanisms of Estrogen Action
2001 Standout
Position-effect protection and enhancer blocking by the chicken β-globin insulator are separable activities
2002
2000 Update of Recommendations for the Use of Tumor Markers in Breast and Colorectal Cancer: Clinical Practice Guidelines of the American Society of Clinical Oncology*
2001
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
1996 Standout
Coregulator Function: A Key to Understanding Tissue Specificity of Selective Receptor Modulators
2004
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Reflections on the Discovery and Significance of Estrogen Receptor β
2005
Genetic Dissection of Complex Traits
1994 StandoutScience
The Role of DNA Methylation in Mammalian Epigenetics
2001 StandoutScience
Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglion
1999
Calcineurin/NFAT Coupling Participates in Pathological, but not Physiological, Cardiac Hypertrophy
2003
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Human vascular smooth muscle cells contain functional estrogen receptor.
1994
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.
1996
Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells
1999
Divergent Pathways Regulate Ligand-Independent Activation of ERα in SK-N-BE Neuroblastoma and COS-1 Renal Carcinoma Cells
1998
GITR Activation Induces an Opposite Effect on Alloreactive CD4+ and CD8+ T Cells in Graft-Versus-Host Disease
2004 StandoutNobel
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
Colocalization of Progesterone Receptors A and B by Dual Immunofluorescent Histochemistry in Human Endometrium during the Menstrual Cycle1
1999
CpG island methylator phenotype in colorectal cancer
1999 Standout
Low-Dose Estrogen Therapy Ameliorates Experimental Autoimmune Encephalomyelitis in Two Different Inbred Mouse Strains
2001
Minireview: Role of Glia in Neuroendocrine Function
2003
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization
1999
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
2006 StandoutNobel
Estrogen Receptor α Signaling in Inflammatory Leukocytes Is Dispensable for 17β-Estradiol-Mediated Inhibition of Experimental Autoimmune Encephalomyelitis
2004
Nuclear Hormone Receptors and Gene Expression
2001
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
1999 StandoutNobel
Works of Giuseppe Pollio being referenced
Estrogen blocks inducible nitric oxide synthase accumulation in LPS-activated microglia cells
2000
Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1
2006
Nucleotide sequence of estrogen receptor cDNA from Sprague-Dawley rat
1992
Estrogen Receptor in Rat Brain Presence in the Hippocampal Formation
1992
Mapping and Characterization of the Functional Domains Responsible for the Differential Activity of the A and B Isoforms of the Human Progesterone Receptor
1997
Oestrogen Prevention of Neural Cell Death Correlates with Decreased Expression of mRNA for the Pro‐Apoptotic Protein Nip‐2
2000
Antisense oligonucleotide blocks progesterone-induced lordosis behavior in ovariectomized rats
1993
Oligonucleotide Squelching Reveals the Mechanism of Estrogen Receptor Autologous Down-Regulation
1997
Estradiol Induces Differential Neuronal Phenotypes by Activating Estrogen Receptor α or β1
2000
16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity.
1996
Cross-coupling between insulin and estrogen receptor in human neuroblastoma cells.
1996
Engineering of a Mouse for the in Vivo Profiling of Estrogen Receptor Activity
2001
Estrogen Prevents the Lipopolysaccharide-Induced Inflammatory Response in Microglia
2001
Estrogen and progesterone induction of survival of monoblastoid cells undergoing TNF‐α‐induced apoptosis
1999
Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3.
1994
Expression of the estrogen‐regulated gene Nip2 during rat brain maturation
2000
Activated estrogen receptor mediates growth arrest and differentiation of a neuroblastoma cell line.
1993
The Novel Progesterone Receptor Antagonists RTI 3021–012 and RTI3021–022 Exhibit Complex Glucocorticoid Receptor Antagonist Activities: Implications for the Development of Dissociated Antiprogestins*
1999