Standout Papers
Citation Impact
Citing Papers
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
2017 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
2019 StandoutNobel
Engineering precision nanoparticles for drug delivery
2020 Standout
Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6
2019
Perovskite solar cells with atomically coherent interlayers on SnO2 electrodes
2021 StandoutNature
DNA recognition by an RNA-guided bacterial Argonaute
2017 StandoutNobel
Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States
2019
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
Controlling and enhancing CRISPR systems
2020 StandoutNobel
Candidate Phyla Radiation Roizmanbacteria From Hot Springs Have Novel and Unexpectedly Abundant CRISPR-Cas Systems
2019 StandoutNobel
Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage
2017
Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis
2018
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Highly Parallel Profiling of Cas9 Variant Specificity
2020
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Rational designs of in vivo CRISPR-Cas delivery systems
2019
Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches
2020 StandoutNobel
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
Recent advances in dynamic docking for drug discovery
2017
Biotechnological advances in bioremediation of heavy metals contaminated ecosystems: an overview with special reference to phytoremediation
2013
Achieving efficient room-temperature catalytic H2 evolution from formic acid through atomically controlling the chemical environment of bimetallic nanoparticles immobilized by isoreticular amine-functionalized metal-organic frameworks
2017
A New Strategy for Heavy Metal Polluted Environments: A Review of Microbial Biosorbents
2017 Standout
State of the Art and Prospects in Metal–Organic Framework (MOF)-Based and MOF-Derived Nanocatalysis
2019 Standout
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Spotlight on the Ballet of Proteins: The Structural Dynamic Properties of Proteins Illuminated by Solution NMR
2020
A data fusion approach to optimize compositional stability of halide perovskites
2021 StandoutNobel
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Metal–ligand interactions in drug design
2018
Halide Perovskites: Is It All about the Interfaces?
2019
Origin of Pronounced Nonlinear Band Gap Behavior in Lead–Tin Hybrid Perovskite Alloys
2018
Target Specificity of Cas9 Nuclease via DNA Rearrangement Regulated by the REC2 Domain
2018
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Role of Molecular Dynamics and Related Methods in Drug Discovery
2016
Property-optimized Gaussian basis sets for molecular response calculations
2010 Standout
PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures
2018
Computational molecular spectroscopy
2021
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
CRISPR-Cas in Streptococcus pyogenes
2019 StandoutNobel
Controlled Assembly and Anomalous Thermal Expansion of Ultrathin Cesium Lead Bromide Nanoplatelets
2023 StandoutNobel
Works of Giulia Palermo being referenced
Pushing the Frontiers of First-Principles Based Computer Simulations of Chemical and Biological Systems
2011
Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain
2018 StandoutNobel
Computational insights into function and inhibition of fatty acid amide hydrolase
2014
Allosteric cross-talk in chromatin can mediate drug-drug synergy
2017
NMR and computational methods for molecular resolution of allosteric pathways in enzyme complexes
2019
Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies
2015
Valence and conduction band tuning in halide perovskites for solar cell applications
2016
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512
2015
Allosteric Motions of the CRISPR–Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics
2019
Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9
2017
Molecular Simulations Highlight the Role of Metals in Catalysis and Inhibition of Type II Topoisomerase
2013
CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations
2017
Catalytic Metal Ions and Enzymatic Processing of DNA and RNA
2015
The Molecular Basis for Dual Fatty Acid Amide Hydrolase (FAAH)/Cyclooxygenase (COX) Inhibition
2015
Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations
2016
Covalent Inhibitors of Fatty Acid Amide Hydrolase: A Rationale for the Activity of Piperidine and Piperazine Aryl Ureas
2011
An Organometallic Compound which Exhibits a DNA Topology‐Dependent One‐Stranded Intercalation Mode
2016