Citation Impact
Citing Papers
Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
2016 StandoutNobel
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
2000 StandoutNature
Targeting autophagy in obesity: from pathophysiology to management
2018
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Genotypic selection of mitochondrial and oncogenic mutations in human tissue suggests mechanisms of age-related pathophysiology
1995
Apoptosis in the nervous system
2000 StandoutNature
The role of DNA damage and repair in aging through the prism of Koch-like criteria
2012
A view on drug resistance in cancer
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Complete molecular remissions induced by patient-specific vaccination plus granulocyte–monocyte colony-stimulating factor against lymphoma
1999
Targeting lipid peroxidation and mitochondrial imbalance in Friedreich's ataxia
2015
Reduced Mitochondrial Membrane Potential and Altered Responsiveness of a Mitochondrial Membrane Megachannel in p53-Induced Senescence
1999
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
2009
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
2010 Standout
Novel Nrf2-Inducer Prevents Mitochondrial Defects and Oxidative Stress in Friedreich’s Ataxia Models
2018
The pathogenesis of Friedreich ataxia and the structure and function of frataxin
2009
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
2008 StandoutNobel
Hallmarks of aging: An expanding universe
2023 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Degeneration of human oncogenes and mitochondrial genes occurs in cells that exhibit age-related pathology
1996
Lateral line hair cell maturation is a determinant of aminoglycoside susceptibility in zebrafish (Danio rerio)
2006
Streptomycin binds to the decoding center of 16 S ribosomal RNA 1 1Edited by M. Gottesman
1997
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
2013 Standout
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
2000 StandoutNobel
Understanding aging: revealing order out of chaos
2004
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
2002 StandoutNature
Susceptibility of HIV-1-TAT transfected cells to undergo apoptosis. Biochemical mechanisms
1999
Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS
2000 StandoutNature
Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions
1999
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Mechanisms of iron–sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes
2006
Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories
2018
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
2011 StandoutNature
Life in extreme environments
2001 StandoutNature
Evidence of a Novel Event during Neuronal Death
1998
Control of apoptosis by IP3and ryanodine receptor driven calcium signals
2000
The anti-oxidant ebselen antagonizes the release of the apoptogenic factor cytochrome c induced by Fe2+/citrate in rat liver mitochondria
2000
Elements of ribosomal drug resistance and specificity
2012 Nobel
Antioxidants and other pharmacological treatments for Friedreich ataxia
2009
Inhibition of mitochondrial permeability transition and release of cytochrome c by anti-apoptotic nucleoside analogues
2002
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Cytochrome c is released in a single step during apoptosis
2005 StandoutNobel
Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition
2000 Standout
Methods in Mammalian Autophagy Research
2010 Standout
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
2015 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
The quest to slow ageing through drug discovery
2020
Mitochondrial dysfunction as a cause of optic neuropathies
2004
A Novel Role for Human Nfs1 in the Cytoplasm
2008
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
A phylogenomic study of DNA repair genes, proteins, and processes
1999
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
Insights into the role of oxidative stress in the pathology of Friedreich ataxia using peroxidation resistant polyunsaturated fatty acids
2013
The Hallmarks of Aging
2013 Standout
The power plant of the cell is also a smithy: The emerging role of mitochondria in cellular iron homeostasis
2008
MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2
2009
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Mitochondrial Aging: Open Questionsa
1998
Mitochondrial DNA and ageing
2006
Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease
2011
The Free Radical Theory of Aging Matures
1998 Standout
Copper Active Sites in Biology
2014 Standout
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
2009
Mitochondrial Optic Neuropathies: How Two Genomes may Kill the Same Cell Type?
2007
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Digital PCR
1999
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
2009 Standout
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro
1999
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Intrigues and Intricacies of the Biosynthetic Pathways for the Enzymatic Quinocofactors: PQQ, TTQ, CTQ, TPQ, and LTQ
2013
Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects
2018
Dietary citrate supplementation enhances longevity, metabolic health, and memory performance through promoting ketogenesis
2021
The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity
2014
The Mononuclear Molybdenum Enzymes
2014 Standout
Apoptotic Death of β Cells after Optic Nerve Transection in Adult Cats
2003 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
C–C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products
2018
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Emerging Droplet Microfluidics
2017 Standout
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases
2008
Eukaryotic LYR Proteins Interact with Mitochondrial Protein Complexes
2015
Frataxin Deficiency Leads to Reduced Expression and Impaired Translocation of NF-E2-Related Factor (Nrf2) in Cultured Motor Neurons
2013
Works of Gino Cortopassi being referenced
Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation
2008
Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice
2009
Pyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression
2009
A molecular and cellular hypothesis for aminoglycoside-induced deafness
1994
Frataxin deficiency impairs mitochondrial biogenesis in cells, mice and humans
2017
Frataxin deficiency induces Schwann cell inflammation and death
2009
There is substantial agreement among interspecies estimates of DNA repair activity
1996
A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
2017
Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones
2007
Using the polymerase chain reaction to estimate mutation frequencies and rates in human cells
1992
Frataxin knockdown causes loss of cytoplasmic iron–sulfur cluster functions, redox alterations and induction of heme transcripts
2006
Induction of the Mitochondrial Permeability Transition Causes Release of the Apoptogenic Factor Cytochrome c
1998
Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells
2005
Mitochondrial disease activates transcripts of the unfolded protein response and cell cycle and inhibits vesicular secretion and oligodendrocyte-specific transcripts
2006
Analysis of oxygen consumption and mitochondrial permeability with age in mice
1998
dATP Causes Specific Release of Cytochrome C from Mitochondria
1998
Frataxin, Iron–Sulfur Clusters, Heme, ROS, and Aging
2006
Frataxin Deficiency Leads to Defects in Expression of Antioxidants and Nrf2 Expression in Dorsal Root Ganglia of the Friedreich's Ataxia YG8R Mouse Model
2013
Proposed molecular and cellular mechanism for aminoglycoside ototoxicity
1994
mtDNA Mutations Confer Cellular Sensitivity to Oxidant Stress That Is Partially Rescued by Calcium Depletion and Cyclosporin A
1997