Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Structural Basis of Wnt Recognition by Frizzled
2012 Science
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
2016
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Sampling of structure and sequence space of small protein folds
2022 StandoutNobel
Computational Design of a Protein-Based Enzyme Inhibitor
2013 StandoutNobel
Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL
2010
Yeast surface display for protein engineering and characterization
2007
Exploration of Alternate Catalytic Mechanisms and Optimization Strategies for Retroaldolase Design
2013 StandoutNobel
Bottom-up de novo design of functional proteins with complex structural features
2021
Improving de novo protein binder design with deep learning
2023 StandoutNobel
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
2012 StandoutNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
An improved yeast transformation method for the generation of very large human antibody libraries
2010
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Engineering explored
2014 StandoutNatureNobel
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site
2017 StandoutNobel
Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’
2012 Nature
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Design of activated serine–containing catalytic triads with atomic-level accuracy
2014 StandoutNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response
2016 StandoutNobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Computational design of novel protein–protein interactions – An overview on methodological approaches and applications
2022
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
EGFR endocytosis requires its kinase activity and N-terminal transmembrane dimerization motif
2013
Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli
2011 StandoutNobel
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Exploitation of binding energy for catalysis and design
2009 StandoutNatureNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling
2010
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
2016 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Insights into Cytokine–Receptor Interactions from Cytokine Engineering
2014
Computational design of environmental sensors for the potent opioid fentanyl
2017 StandoutNobel
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Peptide Ligands for Pro-survival Protein Bfl-1 from Computationally Guided Library Screening
2013
Computational design of a pH-sensitive IgG binding protein
2013 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Works of Ginger Chao being referenced
Fine Epitope Mapping of anti-Epidermal Growth Factor Receptor Antibodies Through Random Mutagenesis and Yeast Surface Display
2004
Isolating and engineering human antibodies using yeast surface display
2006
Bispecific Designed Ankyrin Repeat Proteins (DARPins) Targeting Epidermal Growth Factor Receptor Inhibit A431 Cell Proliferation and Receptor Recycling
2011