Citation Impact
Citing Papers
Taking Cell-Matrix Adhesions to the Third Dimension
2001 StandoutScience
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages.
2004
Roles of Individual N-Glycans for ATP Potency and Expression of the Rat P2X1 Receptor
2000
The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells
2009
Developmental changes in P2X purinoceptors on glycinergic presynaptic nerve terminals projecting to rat substantia gelatinosa neurones
2001
Different patterns of Ca2+ signals are induced by low compared to high concentrations of P2Y agonists in microglia
2006
A Natural Dominant Negative P2X1 Receptor Due to Deletion of a Single Amino Acid Residue
2000
P2X7 nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons
2005
Increased Proliferation Rate of Lymphoid Cells Transfected with the P2X7 ATP Receptor
1999
Effects of the P2-purinoceptor antagonists suramin and pyridoxal-phosphate-6-azophenyl-2′,4′-disulfonic acid on glutamatergic synaptic transmission in rat dorsal horn neurons of the spinal cord
1998
COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord
2006
Functional and Biochemical Evidence for Heteromeric ATP-gated Channels Composed of P2X1 and P2X5Subunits
1999
Complexities of Measuring Antagonist Potency at P2X7Receptor Orthologs
2001
Trinitrophenyl-Substituted Nucleotides Are Potent Antagonists Selective for P2X1, P2X3, and Heteromeric P2X2/3 Receptors
1998
αvβ3 and αvβ5 integrin antagonists inhibit angiogenesis in vitro
2003
Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor
1997
Possible Involvement of P2X7 Receptor Activation in Microglial Neuroprotection against Focal Cerebral Ischemia in Rats
2008
Functional evidence for multiple purinoceptor subtypes in the rat medial vestibular nucleus
1997
ATP and glutamate are released from separate neurones in the rat medial habenula nucleus: frequency dependence and adenosine‐mediated inhibition of release
1998
Pannexin1 is part of the pore forming unit of the P2X7 receptor death complex
2007
Extracellular adenosine triphosphate affects neural cell adhesion molecule (NCAM)-mediated cell adhesion and neurite outgrowth
1999
P2X7 receptors on microglial cells mediate injury to cortical neurons in vitro
2006
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors
2000 Nature
17β-estradiol attenuates α, β-meATP-induced currents in rat dorsal root ganglion neurons
2005
P2X purinoceptor subtypes on paraventricular nucleus neurones projecting to the rostral ventrolateral medulla in the rat
2005
P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
2004
Cloning and characterization of the murine P2XM receptor gene
1998
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Upregulation of the P2X7 receptor after cryogenic injury to rat brain
2009
Guinea‐pig sympathetic neurons express varying proportions of two distinct P2X receptors
2000
P2 receptor web: Complexity and fine-tuning
2006
Long‐term potentiation and long‐term depression induced by local application of ATP to hippocampal CA1 neurons of the Guinea pig
2002
Sense and specificity: a molecular identity for nociceptors
1999 StandoutNobel
P2X receptors in the rat uterine cervix, lumbosacral dorsal root ganglia, and spinal cord during pregnancy
2005
Evidence That ATP Participates in the Pathophysiology of Pilocarpine‐Induced Temporal Lobe Epilepsy: A Fluorimetric, Immunohistochemical, and Western Blot Studies
2002
P2X7 nucleotide receptor activation enhances IFNγ‐induced type II nitric oxide synthase activity in BV‐2 microglial cells
2003
Purinoceptors in microglia and neuropathic pain
2006
Introduction: P2 Receptors
2004
Two different ionotropic receptors are activated by ATP in rat microglia
1999
P2X7 Receptors in Rat Brain: Presence in Synaptic Terminals and Granule Cells
2003
Expression of P2X and P2Y receptors in the intramural parasympathetic ganglia of the cat urinary bladder
2005
Selective inflammatory stimulations enhance release of microglial response factor (MRF)‐1 from cultured microglia
2002
Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system
1997
A Protein Kinase C Site Highly Conserved in P2X Subunits Controls the Desensitization Kinetics of P2X2 ATP-gated Channels
2000
Kinetic characterization of ATP diphosphohydrolase and 5′‐nucleotidase activities in cells cultured from submandibular salivary glands of rats
2006
P2 receptor modulation and cytotoxic function in cultured CNS neurons
2002
P2X receptors in cochlear Deiters' cells
1998
Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin
2001
Diinosine pentaphosphate: an antagonist which discriminates between recombinant P2X3 and P2X2/3 receptors and between two P2X receptors in rat sensory neurones
2000
ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia
2000
Adenosine triphosphate-evoked currents in cultured dorsal root ganglion neurons obtained from rat embryos: desensitization kinetics and modulation of glutamate release
2000
P2 receptor-stimulation influences axonal outgrowth in the developing hippocampus in vitro
2006
Developmental expression of metabotropic P2Y1 and P2Y2 receptors in freshly isolated astrocytes from rat hippocampus
2001
Are there functional P2X receptors on cell bodies in intact dorsal root ganglia of rats?
1998
Iono- and metabotropically induced purinergic calcium signalling in rat neocortical neurons
1998
ATP facilitates spontaneous glycinergic IPSC frequency at dissociated rat dorsal horn interneuron synapses
2000
Vasoconstrictor responses via P2X‐receptors are selectively antagonized by NF023 in rabbit isolated aorta and saphenous artery
1997
Microglial phagocytosis attenuated by short‐term exposure to exogenous ATP through P2X7receptor action
2009
Expression of two ATP-gated ion channels, P2X5 and P2X6, in developing chick skeletal muscle
1999
Involvement of P2 receptors in the growth and survival of neurons in the CNS
2005
P2X7 Receptor Signaling Pathway as a Therapeutic Target for Neurodegenerative Diseases
2010
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Stimulation of Ca2+ influx through ATP receptors on rat brain synaptosomes: identification of functional P2X7 receptor subtypes
2002
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation
2009
ATP‐induced [Ca2+]i changes and depolarization in GH3 cells
2000
P2X5 receptors are expressed on neurons containing arginine vasopressin and nitric oxide synthase in the rat hypothalamus
2006
Differential Assembly of Rat Purinergic P2X7 Receptor in Immune Cells of the Brain and Periphery
2001
Activation of P2X receptors for adenosine triphosphate evokes cardiorespiratory reflexes in anaesthetized rats
1998
The distribution of P2X5 purinergic receptors in the enteric nervous system of mouse
2004
Properties of native P2X receptors in rat trigeminal mesencephalic nucleus neurones: lack of correlation with known, heterologously expressed P2X receptors
2001
Desensitization of the P2X2 receptor controlled by alternative splicing
1997
Conserved Cysteine Residues in the Extracellular Loop of the Human P2X1Receptor Form Disulfide Bonds and Are Involved in Receptor Trafficking to the Cell Surface
2002
Evidence for P2X3 receptors in the developing rat brain
1998
Inflammatory Mediators Potentiate ATP-gated Channels through the P2X3 Subunit
2001
P2X receptor‐mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint
1998
Characterization of cultured dorsal root ganglion neuron P2X receptors
1999
The P2X7 receptor–pannexin connection to dye uptake and IL-1β release
2009
Synaptic corelease of ATP and GABA in cultured spinal neurons
1999
ATP-induced inhibition of gap junctional communication is enhanced by interleukin-1 β treatment in cultured astrocytes
2004
Inactivation of P2X2 purinoceptors by divalent cations
2000
Purine-mediated signalling in pain and visceral perception
2001
Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels
2000
Purine and pyrimidine receptors
2007
ATP stimulation of Ca2+‐dependent plasminogen release from cultured microglia
1998
Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals
1997
Single channel properties of P2X ATP receptors in outside‐out patches from rat hippocampal granule cells
2000
Functional expression of P2X7 receptors in non-neuronal cells of rat dorsal root ganglia
2005
Characterization and immunohistochemical localization of nucleoside triphosphate diphosphohydrolase (NTPDase) in pig adrenal glands (presence of a non-sedimentable isoform)
2000
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Keratinocyte ATP Release Assay for Testing Skin-Irritating Potentials of Structurally Diverse Chemicals
2003
Pore properties and pharmacological features of the P2X receptor channel in airway ciliated cells
2006
Adenosine Triphosphate Induces Ca2+ Signal in Epithelial Cells of the Mouse Caput Epididymis Through Activation of P2X and P2Y Purinergic Receptors1
2003
Apparent species differences in the kinetic properties of P2X7 receptors
2000
Expression of Nucleotide P2X Receptor Subtypes during Spermatogenesis in the Adult Rat Testis
2001
Molecular Cloning and Characterization of a Novel ATP P2X Receptor Subtype from Embryonic Chick Skeletal Muscle
2000
Purinergic and Vanilloid Receptor Activation Releases Glutamate from Separate Cranial Afferent Terminals in Nucleus Tractus Solitarius
2004
IMPLICATION OF ATP RECEPTORS IN BRAIN FUNCTIONS
1996
Novel variant of the P2X2 ATP receptor from the guinea pig organ of Corti
1998
Transient expression of P2X1 receptor subunits of ATP-gated ion channels in the developing rat cochlea
2001
Purinergic regulation of cation conductances and intracellular Ca2+ in cultured rat retinal pigment epithelial cells
1999
Molecular Assembly of the Extracellular Domain of P2X2, an ATP-Gated Ion Channel
1997
Genomic structure, developmental distribution and functional properties of the chicken P2X5 receptor
2001
Molecular physiology of P2 receptors in the central nervous system
2003
Microglial activation by purines and pyrimidines
2002
Functional properties of heteromeric P2X1/5 receptors expressed in HEK cells and excitatory junction potentials in guinea-pig submucosal arterioles
2000
Increase in intracellular Ca2+ and calcitonin gene-related peptide release through metabotropic P2Y receptors in rat dorsal root ganglion neurons
2002
Changes in expression of P2X purinoceptors in rat cerebellum during postnatal development
2005
Mutual occlusion of P2X ATP receptors and nicotinic receptors on sympathetic neurons of the guinea‐pig
1998
Heterogeneity of P2X Receptors in Sympathetic Neurons: Contribution of Neuronal P2X1 Receptors Revealed Using Knockout Mice
2004
Expression and Trans-synaptic Regulation of P2x4 and P2z Receptors for Extracellular ATP in Parotid Acinar Cells
1998
Purinergic Signalling in the Medullary Mechanisms of Respiratory Control in the Rat: Respiratory Neurones Express the P2X2 Receptor Subunit
2003
Electron-immunocytochemical localization of P2X 1 receptors in the rat cerebellum
1998
P2X receptor-mediated purinergic sensory pathways to the spinal cord dorsal horn
2004
Mechanisms of P2 receptor‐evoked DNA synthesis in thyroid FRTL‐5 cells
2001
Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes
2000
Pyridoxalphosphate-6-azophenyl-2′,4′-disulfonic acid can antagonize the purinoceptor-mediated inhibition of M-current in bullfrog sympathetic neurons
2003
Detection of P2X purinergic receptors on human B lymphocytes
2001
Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan‐inflamed and neuropathic rats
2000
Extracellular ATP activates ERK1/ERK2 via a metabotropic P2Y1 receptor in a Ca2+ independent manner in differentiated human skeletal muscle cells
2006
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia
2005
Endogenous opioid mechanisms partially mediate P2X3/P2X2/3‐related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain
2005
Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression
2006
Epithelial P2X purinergic receptor channel expression and function
1999
Modulation of ATP‐responses at recombinant rP2X4 receptors by extracellular pH and zinc
1999
Chapter 7 Cloning, functional characterization and developmental expression of a P2X receptor from chick embryo
1999
Coexpression of mRNAs for P2X<sub>1</sub>, P2X<sub>2</sub> and P2X<sub>4</sub> Receptors in Rat Vascular Smooth Muscle: An in situ Hybridization and RT-PCR Study
1998
The Involvement of an ATP-Gated Ion Channel, P2X1, in Thymocyte Apoptosis
1996
P2X7 Mediates Superoxide Production in Primary Microglia and Is Up-regulated in a Transgenic Mouse Model of Alzheimer's Disease
2003
Emerging challenges of assigning P2X7 receptor function and immunoreactivity in neurons
2006
The cytokine IL‐1β transiently enhances P2X7 receptor expression and function in human astrocytes
2004
Chapter 16 The functions of ATP receptors in the synaptic transmission in the hippocampus
1999
Purinergic modulation of microglial cell activation
2006
Co-release of endogenous ATP and [3H]noradrenaline from rat hypothalamic slices: origin and modulation by α2-adrenoceptors
1997
Characterization of P2 receptors modulating neural activity in rat rostral ventrolateral medulla
1999
Localization and Functional Expression of Splice Variants of the P2X2 Receptor
1997
Co-Expression of P2X1 and P2X5 Receptor Subunits Reveals a Novel ATP-Gated Ion Channel
1998
P2X receptors in mouse Leydig cells
2005
The Expression of P2X3Purinoreceptors in Sensory Neurons: Effects of Axotomy and Glial-Derived Neurotrophic Factor
1998
Distinct modulation of evoked and spontaneous EPSCs by purinoceptors in the nucleus tractus solitarii of the rat
2001
Changes in intracellular Ca2+ by activation of P2 receptors in submucosal neurons in short-term cultures
2000
Dynamic control over cell adhesive properties using molecular-based surface engineering strategies
2009 StandoutNobel
Evidence that multiple P2X purinoceptors are functionally expressed in rat supraoptic neurones
1999
P2X receptor subtype‐specific modulation of excitatory and inhibitory synaptic inputs in the rat brainstem
2004
Distinct ATP-activated currents in different types of neurons dissociated from rat dorsal root ganglion
1999
Single channel properties of ATP-gated cation channels (P2X receptors) heterologously expressed in Chinese hamster ovary cells
1996
Purinergic modulation of cardiovascular function in the rat locus coeruleus
2005
A role for P2X7in microglial proliferation
2006
Identification and localisation of ATP P2X receptors in rat midbrain
1999
Sequential expression of three receptor subtypes for extracellular ATP in developing rat skeletal muscle
2001
Ion channels in glial cells
2000
Analysis of purinergic and cholinergic fast synaptic transmission to identified myenteric neurons
2003
The Distribution of P2X Receptor Clusters on Individual Neurons in Sympathetic Ganglia and Their Redistribution on Agonist Activation
2000
Danger signals: SOS to the immune system
2001
Desensitization, recovery and Ca2+-dependent modulation of ATP-gated P2X receptors in nociceptors
1997
Neuroepithelial cells and associated innervation of the zebrafish gill: A confocal immunofluorescence study
2003
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
1998 StandoutNobel
Isoquinolines as Antagonists of the P2X7 Nucleotide Receptor: High Selectivity for the Human versus Rat Receptor Homologues
1998
The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat
1999
Molecular cloning, functional characterization and possible cooperativity between the murine P2X4 and P2X4a receptors
1999
ATP-induced in vivo neurotoxicity in the rat striatum via P2 receptors
2002
Pharmacological and molecular characterization of P2X receptors in rat pelvic ganglion neurons
1998
P2X receptors in peripheral neurons
2001
The human P2X4 receptor gene is alternatively spliced
1998
P2X7 receptors in the nervous system
2006
CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness
2002
Cellular localization of P2X7 receptor mRNA in the rat brain
2008
Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP‐ATP and enhancement by the P2X3 allosteric modulator, cibacron blue
2001
Rat chromaffin cells lack P2X receptors while those of the guinea‐pig express a P2X receptor with novel pharmacology
1999
2′,3′‐O‐(2,4,6‐ trinitrophenyl) adenosine 5′‐triphosphate (TNP‐ATP)–a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels
1998
N-methyl-d -glucamine and propidium dyes utilize different permeation pathways at rat P2X7 receptors
2005
Topological analysis of the ATP‐gated ionotrophic P2X2 receptor subunit
1998
P2x‐purinoceptors of myenteric neurones from the guinea‐pig ileum and their unusual pharmacological properties
1996
P2X receptors in the rat duodenal villus
1999
Adenosine triphosphate inhibits cytokine release from lipopolysaccharide-activated microglia via P2y receptors
2003
Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors
2002
Bi-directional signal transduction by integrin receptors
2000
Properties of ATP receptor-mediated synaptic transmission in the rat medial habenula
1997
P2X receptor expression in mouse urinary bladder and the requirement of P2X1 receptors for functional P2X receptor responses in the mouse urinary bladder smooth muscle
2000
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Ionotropic P2X purinoreceptors mediate synaptic transmission in rat pyramidal neurones of layer II/III of somato‐sensory cortex
2002
The Suramin Analog 4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic Acid (NF110) Potently Blocks P2X3 Receptors: Subtype Selectivity Is Determined by Location of Sulfonic Acid Groups
2006
Effects of A‐317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration
2003
P2X7/P2Z Purinoreceptor-mediated Activation of Transcription Factor NFAT in Microglial Cells
1999
Ca2+ permeability and kinetics of glutamate receptors in rat medial habenula neurones: implications for purinergic transmission in this nucleus
1999
A purinergic component of the excitatory postsynaptic current mediated by P2X receptors in the CA1 neurons of the rat hippocampus
1998
Diadenosine polyphosphate receptors
2000
Microglia response and P2 receptor participation in oxygen/glucose deprivation-induced cortical damage
2005
P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system
2002
TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics
2002
Neuron‐specific distribution of P2X7 purinergic receptors in the monkey retina
2003
Extracellular ATP as a signaling molecule for epithelial cells
2003
Pathophysiology and Therapeutic Potential of Purinergic Signaling
2006
Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder
2006
Antagonism by the suramin analogue NF279 on human P2X1 and P2X7 receptors
2000
P2X receptors and synaptic plasticity
2008
Ω-conotoxin GVIA potently inhibits the currents mediated by P2X receptors in rat DRG neurons
2001
Integrins in angiogenesis: multitalented molecules in a balancing act
2003
Calcium permeability and block at homomeric and heteromeric P2X2and P2X3receptors, and P2X receptors in rat nodose neurones
1998
Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain
2004
Ultrastructural Localisation of ATP-Gated P2X2Receptor Immunoreactivity in Vascular Endothelial Cells in Rat Brain
2000
Detrusor overactivity induced by intravesical application of adenosine 5′-triphosphate under different delivery conditions in rats
2005
ATP-Induced Killing of Mycobacteria by Human Macrophages Is Mediated by Purinergic P2Z(P2X7) Receptors
1997
Chapter 28 Purinoceptors in human B-lymphocytes
1999
A Glu-496 to Ala Polymorphism Leads to Loss of Function of the Human P2X7 Receptor
2001
Multiple P2X receptors on guinea‐pig pelvic ganglion neurons exhibit novel pharmacological properties
2001
Modulation by oxytocin of ATP-activated currents in rat dorsal root ganglion neurons
2002
Electron microscopic localisation of P2X4 receptor subunit immunoreactivity to pre- and post-synaptic neuronal elements and glial processes in the dorsal vagal complex of the rat
2004
The mechanism by which ethanol inhibits rat P2X4 receptors is altered by mutation of histidine 241
2005
Cibacron blue allosterically modulates the rat P2X4 receptor
1998
Unique Functional Properties of a Sensory Neuronal P2X ATP‐Gated Channel from Zebrafish
2000
Deletion of the P2X7Nucleotide Receptor Reveals Its Regulatory Roles in Bone Formation and Resorption
2003
Pharmacological characterization of ATP‐ and LPS‐induced IL‐1β release in human monocytes
1999
Localization of P2X3 receptors and coexpression with P2X2 receptors during rat embryonic neurogenesis
2002
Cell type‐specific ATP‐activated responses in rat dorsal root ganglion neurons
1999
Activation of P2X7 receptors induced [3H]GABA release from the RBA‐2 type‐2 astrocyte cell line through a Cl−/HCO3−‐dependent mechanism
2001
Depletion of substance P from rat primary sensory neurons by ATP, an implication of P2X receptor-mediated release of substance P
2001
Gene structure, chromosomal localization, cDNA cloning and expression of the mouse ATP-gated ionotropic receptor P2X5 subunit
2001
Selective labeling of central and peripheral sensory neurons in the developing zebrafish using P2X3 receptor subunit transgenes
2006
Zn2+ modulation of ATP‐responses at recombinant P2X2 receptors and its dependence on extracellular pH
1998
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors
2002
P2X (Purinergic) receptor distributions in rat blood vessels
1999
P2X2 receptor immunoreactivity in the dorsal vagal complex and area postrema of the rat
2000
Pseudoapoptosis Induced by Brief Activation of ATP-gated P2X7 Receptors
2005
Functional evidence of distinct ATP activation sites at the human P2X7 receptor
2001
Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2
2005
Extracellular ATP Triggers Tumor Necrosis Factor‐α Release from Rat Microglia
2000
Immunoreactivity to P2X6 receptors in the rat hypothalamo-neurohypophysial system: an ultrastructural study with extravidin and colloidal gold-silver labelling
2001
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Reduction by sevoflurane of adenosine 5′-triphosphate-activated inward current of locus coeruleus neurons in pontine slices of rats
2001
Developmental downregulation of P2X3 receptors in motoneurons of the compact formation of the nucleus ambiguus
2005
Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor
1999
Purinoceptors Evoke Different Electrophysiological Responses in Pancreatic Ducts
1999
Characterization of Recombinant Human P2X4 Receptor Reveals Pharmacological Differences to the Rat Homologue
1997
Distribution of P2X receptors in the rat adrenal gland
1999
Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis
2006
Bidirectional modulation of P2X receptor‐mediated response by divalent cations in rat dorsal motor nucleus of the vagus neurons
2001
Extracellular ATP and nerve growth factor intensify hypoglycemia‐induced cell death in primary neurons: role of P2 and NGFRp75 receptors
2002
Gene expression of the P2X receptors in the rat retina
1998
Up-Regulation of P2X4Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain
2008
Alterations in the expression of P2X1 receptors in failing and nondiseased human atria
1998
Chapter 19 ATP receptor-mediated component of the excitatory synaptic transmission in the hippocampus
1999
Changes in the gene expression of six subtypes of P2X receptors in rat dorsal root ganglion after spinal nerve ligation
2003
Pharmacological characterization of recombinant human and rat P2X receptor subtypes
1999
Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor
2006 Standout
Pharmacological characterization of the P2X 7 receptor on human macrophages using the patch-clamp technique
2002
Modification of neuropathic pain sensation through microglial ATP receptors
2007
P2X7Receptor Expression after Ischemia in the Cerebral Cortex of Rats
2004
Altered Cytokine Production in Mice Lacking P2X7Receptors
2001
Functional characterization of the P2X4 receptor orthologues
2000
Pharmacological properties of P2X3‐receptors present in neurones of the rat dorsal root ganglia
1998
The function of microglia through purinergic receptors: Neuropathic pain and cytokine release
2005
Extracellular matrix in development of the early embryo
2001
Expression of Purinergic Receptor Channels and Their Role in Calcium Signaling and Hormone Release in Pituitary Gonadotrophs
1996
The single-channel properties of purinergic P2X ATP receptors in outside-out patches from rat hypothalamic paraventricular parvocells
2001
Inside-out integrin signalling
1992
Coexpression of functional P2X and P2Y nucleotide receptors in single cerebellar granule cells
2003
Altered Hippocampal Synaptic Potentiation in P2X4Knock-Out Mice
2006
Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat
2003
Evidence for the involvement of purinergic signalling in the control of respiration
2001
Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat
1997
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
2003 StandoutNature
P2X7 receptor immunoreactive profile confined to resting and activated microglia in the epileptic brain
2006
Glomerular expression of the ATP-sensitive P2X7 receptor in diabetic and hypertensive rat models
2004
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
1993
Molecular properties of P2X receptors
2006
Modulation of the Purinergic P2X7Receptor Attenuates Lipopolysaccharide-Mediated Microglial Activation and Neuronal Damage in Inflamed Brain
2007
Chemotactic activity of extracellular nucleotideson human immune cells.
2007
Cytolytic P2X purinoceptors
1998
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
2004 StandoutNature
Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro
2003
Amino Acid Residues Involved in Gating Identified in the First Membrane-spanning Domain of the Rat P2X2 Receptor
2001
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Effect of extracellular adenosine 5′-triphosphate on principal neurons of the rat ventral tegmental area
1998
Contributions of the C-terminal Domain to the Control of P2X Receptor Desensitization
1999
Pore dilation of neuronal P2X receptor channels
1999
Vascular smooth muscle cell growth‐promoting factor/F‐spondin inhibits angiogenesis via the blockade of integrin αvβ3 on vascular endothelial cells
2001
Up‐regulation of ectonucleotidase activity after cortical stab injury in rats
2006
Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells
2007
Molecular cloning and functional characterization of the zebrafish ATP‐gated ionotropic receptor P2X3 subunit
2000
Fast synaptic transmission mediated by P2X receptors in CA3 pyramidal cells of rat hippocampal slice cultures
2001
P2X purinoceptors and sensory transmission
2006
Molecular physiology of p2x receptors and atp signalling at synapses
2001
P2X2receptors are essential for [Ca2+]iincreases in response to ATP in cultured rat myenteric neurons
2005
Antagonist effects on human P2X7 receptor‐mediated cellular accumulation of YO‐PRO‐1
2000
Changes in purinergic signalling in developing and ageing rat tail artery: Importance for temperature control
2005
Differential regulation of P2X3 mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia
2001
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Suramin inhibits spinal cord microglia activation and long-term hyperalgesia induced by formalin injection
2004
A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat
2006
Asymmetric Self-Renewal and Commitment of Satellite Stem Cells in Muscle
2007
Regulation by P2 agonists of the intracellular calcium concentration in epithelial cells freshly isolated from rat trachea
1999
The antagonist trinitrophenyl‐ATP reveals co‐existence of distinct P2X receptor channels in rat nodose neurones
1998
Mechanisms of Release of Nucleotides and Integration of Their Action as P2X- and P2Y-Receptor Activating Molecules
2003
Neonatal Hypothyroidism Affects the Adenine Nucleotides Metabolism in Astrocyte Cultures from Rat Brain
2006
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Lesional accumulation of P2X4 receptor+ macrophages in rat CNS during experimental autoimmune encephalomyelitis
2005
P2X7 receptors in the enteric nervous system of guinea‐pig small intestine
2001
Pharmacology of P2X channels
2006
The P2X7 ATP receptor modulates renal cyst development in vitro
2004
Depression of C fiber-evoked activity by intrathecally administered reactive red 2 in rat thalamic neurons
1998
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Mutation of histidine 286 of the human P2X4 purinoceptor removes extracellular pH sensitivity
2000
P2X3 is expressed by DRG neurons that terminate in inner lamina II
1998
Molecular characterization and pharmacological properties of the human P2X3 purinoceptor
1997
Identification of Amino Acid Residues Contributing to the ATP-binding Site of a Purinergic P2X Receptor
2000
Identification of amino acids within the P2X2 receptor C‐terminus that regulate desensitization
1999
Expression of P2X receptors on rat microglial cells during early development
2005
Localization of ATP-gated P2X receptor immunoreactivity in rat sensory and sympathetic ganglia
1998
Chapter 29 The P2Z/P2X7 receptor of microglial cells: A novel immunomodulatory receptor
1999
One‐way cross‐desensitization between P2X purinoceptors and vanilloid receptors in adult rat dorsal root ganglion neurones
2000
P2 receptors and neuronal injury
2006
Molecular cloning and functional expression of Xenopus laevis oocyte ATP-activated P2X4 channels1The nucleotide sequence data reported in this paper have been deposited in the GenBank database under accession Nos. AF308148 (xP2X4a), AF308149 (xP2X4b), AF308150 (xP2X4c), AF308151 (xP2X4d), AF308152 (xP2X4e) and AF308153 (xP2X4f).1
2001
Sustained Calcium Entry through P2X Nucleotide Receptor Channels in Human Airway Epithelial Cells
2003
Functional Characterization of a P2X Receptor from Schistosoma mansoni
2004
Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of postsynaptic P2X receptors
2006
Activation of ATP receptor increases the cytosolic Ca2+ concentration in ventral tegmental area neurons of rat brain
2002
ATP selectively suppresses the synthesis of the inflammatory protein microglial response factor (MRF)-1 through Ca2+ influx via P2X7 receptors in cultured microglia
2002
Glial cells, but not interstitial cells, express P2X7, an ionotropic purinergic receptor, in rat gastrointestinal musculature
2003
Hetero-oligomeric Assembly of P2X Receptor Subunits
1999
Structure and chromosomal mapping of the mouse P2X3 gene
1997
Molecular and Functional Characterization of Human P2X2Receptors
1999
The birth and postnatal development of purinergic signalling
2010
Connexin channel permeability to cytoplasmic molecules
2007
Local regulation of vasopressin and oxytocin secretion by extracellular ATP in the isolated posterior lobe of the rat hypophysis
1999
The Role of Positively Charged Amino Acids in ATP Recognition by Human P2X1 Receptors
2000
Adenosine 5??-Triphosphate Axis in Obstructive Airway Diseases
2002
P2X7 receptor inhibition improves recovery after spinal cord injury
2004
ATP stimulates peripheral axons in human, rat and mouse — differential involvement of A2B adenosine and P2X purinergic receptors
2002
State-dependent cross-inhibition between transmitter-gated cation channels
2000 Nature
Synaptic P2X receptors
2001
Purinergic (P2X7) Receptor Activation of Microglia Induces Cell Death via an Interleukin-1-Independent Mechanism
2002
P2X purinoceptor‐mediated excitation of trigeminal lingual nerve terminals in an in vitro intra‐arterially perfused rat tongue preparation
2000
Identification of a Site That Modifies Desensitization of P2X2Receptors
1998
Identification of Amino Acid Residues Contributing to Desensitization of the P2X2 Receptor Channel
1998
Are second messengers crucial for opening the pore associated with P2X7 receptor?
2004
ATP-evoked Ca2+ transients and currents in murine thymocytes: possible role for P2X receptors in death by neglect
1999
Distinct ATP receptors on pain-sensing and stretch-sensing neurons
1997 Nature
Diinosine pentaphosphate (IP5I) is a potent antagonist at recombinant rat P2X1 receptors
1999
P2X2 and P2Y1 immunofluorescence in rat neostriatal medium‐spiny projection neurones and cholinergic interneurones is not linked to respective purinergic receptor function
2004
Activation by P2X7 Agonists of Two Phospholipases A2 (PLA2) in Ductal Cells of Rat Submandibular Gland
1998
Peripheral P2X receptors and nociception: interactions with biogenic amine systems
2004
Subunit‐specific P2X‐receptor expression defines chemosensory properties of trigeminal neurons
2004
Purinergic receptor expression in the regenerating epidermis in a rat model of normal and delayed wound healing
2003
Localisation of P2X
1999
Evidence for P2Y-type ATP receptors on the serosal membrane of frog skin epithelium
1999
Differential increases in P2X receptor levels in rat vagal efferent neurones following a vagal nerve section
2003
Involvement of P2X and P2Y receptors in microglial activation in vivo
2007
Upregulated Expression of Purinergic P2X7Receptor in Alzheimer Disease and Amyloid-β Peptide-Treated Microglia and in Peptide-Injected Rat Hippocampus
2006
Lack of run‐down of smooth muscle P2X receptor currents recorded with the amphotericin permeabilized patch technique, physiological and pharmacological characterization of the properties of mesenteric artery P2X receptor ion channels
2000
The opposing roles of laminin-binding integrins in cancer
2016
Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
2002
Evidence for three additional P2X2 purinoceptor isoforms produced by alternative splicing in the adult rat vestibular end-organs
1998
Ionic selectivity of native ATP‐activated (P2X) receptor channels in dissociated neurones from rat parasympathetic ganglia
2001
Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat
1999
Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT
2008
ATP‐gated ion channel P2X3 is increased in human inflammatory bowel disease
2001
Contributions of P2X3 homomeric and heteromeric channels to acute and chronic pain
2003
Ecto-Nucleotidases and Nucleoside Transporters Mediate Activation of Adenosine Receptors on Hippocampal Mossy Fibers by P2X7Receptor Agonist 2′-3′-O-(4-Benzoylbenzoyl)-ATP
2004
Expression of functional purinergic receptors in pulmonary neuroepithelial bodies and their role in hypoxia chemotransmission
2004
Involvement of purinergic signalling in central mechanisms of body temperature regulation in rats
2002
Selectivity of diadenosine polyphosphates for rat P2X receptor subunits
1999
Antagonistic properties of the suramin analogue NF023 at heterologously expressed P2X receptors
1999
The P2X7 receptor from Xenopus laevis: formation of a large pore in Xenopus oocytes
2002
Evidence that P2X purinoceptors mediate the excitatory effects of αβmethylene-ADP in rat locus coeruleus neurones
1998
P2 receptors in human heart: upregulation of P2X6 in patients undergoing heart transplantation, interaction with TNFα and potential role in myocardial cell death
2005
Cloning and characterization of two novel zebrafish P2X receptor subunits
2002
Identification of amino acid residues contributing to the pore of a P2X receptor
1997
Extracellular ATP directly gates a cation‐selective channel in rabbit airway ciliated epithelial cells
1998
Two mechanisms for inward rectification of current flow through the purinoceptor P2X2 class of ATP‐gated channels
1998
Points of control in inflammation
2002 StandoutNature
Involvement of P2X receptor subtypes in ATP-induced enhancement of the cough reflex sensitivity
2005
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
Development of P2X receptor clusters on smooth muscle cells in relation to nerve varicosities in the rat urinary bladder
1999
Alcohol action on membrane ion channels gated by extracellular ATP (P2X receptors)
1999
Extracellular mRNA Induces Dendritic Cell Activation by Stimulating Tumor Necrosis Factor-α Secretion and Signaling through a Nucleotide Receptor
2002 StandoutNobel
Extracellular nucleotide signaling in the inner ear
1998
The past, present and future of purine nucleotides as signalling molecules
1997
Nucleotide receptors
1997
ATP as a presynaptic modulator
2000
Supersensitivity of P2X7 receptors in cerebrocortical cell cultures after in vitro ischemia
2005
Pharmacological characterization of P2 purinoceptor types in rat locus coeruleus neurons
1996
Immunoreactive localisation of P2Y1 receptors within the rat and human nodose ganglia and rat brainstem: comparison with [α33P]deoxyadenosine 5′-triphosphate autoradiography
2002
Cloning and functional characterisation of the mouse P2X7 receptor
1998
Extracellular ATP: A Further Modulator in Neuroendocrine Control of the Thymus
1999
Cloning and Expression of a P2yPurinoceptor from the Adult Bovine Corpus Callosum
1998
Functional Role of Alternative Splicing in Pituitary P2X2Receptor-Channel Activation and Desensitization
1998
P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels
1998
The P2X7Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
2009
Proteomic and functional evidence for a P2X7 receptor signalling complex
2001
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
2000 StandoutNature
Biophysics of P2X receptors
2006
P2X1 receptor membrane redistribution and down-regulation visualized by using receptor-coupled green fluorescent protein chimeras
2000
Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor
1997
Pharmacological comparison of P2X receptors on rat coeliac, mouse coeliac and mouse pelvic ganglion neurons
2000
Integrins
2002 Standout
Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
2006
Membrane Topology of an ATP-gated Ion Channel (P2X Receptor)
1998
Molecular cloning and functional expression of a novel rat heart P2X purinoceptor
1996
Activation of mouse microglial cells affects P2 receptor signaling
2000
P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestine
2003
ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Synaptic Purinoceptors: the Stage for ATP to Play Its “Dual-Role”
2004
P2X 2 and P2X 3 purinoceptors in the rat enteric nervous system
2004
Molecular characterization of the zebrafish P2X receptor subunit gene family
2003
Expression of P2X receptors in rat choroid plexus
2005
Distribution of P2X purinoceptor clusters on individual rat dorsal root ganglion cells
2000
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices
1998
Expression of the P2X7-receptor subunit in neurons of the rat retina
1998
P2X7 receptors: Properties and relevance to CNS function
2006
Activation of the P2Z/P2X7Receptor in Human Lymphocytes Produces a Delayed Permeability Lesion: Involvement of Phospholipase D
1999
Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds
1999
Ultrastructural localisation of ATP-gated P2X2 receptor immunoreactivity in the rat hypothalamo-neurohypophysial system
1999
Fading and rebound of P2X2 currents at millimolar ATP concentrations caused by low pH
1998
Inhibition by ATP of calcium oscillations in rat cultured hippocampal neurones
1997
Implantation and the placenta: key pieces of the development puzzle
1994 StandoutScience
Neurotransmitter receptors on microglia
2007
ATP as a peripheral mediator of pain
2000
ATP binding site of P2X channel proteins: structural similarities with class II aminoacyl‐tRNA synthetases
1998
Modulation of sodium currents in rat sensory neurons by nucleotides
2004
Families of ion channels with two hydrophobic segments
1996
Purinergic receptor modulation of BV-2 microglial cell activity: Potential involvement of p38 MAP kinase and CREB
2005
Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice
1999
Extracellular Nucleotides Activate non‐Selective Cation and Ca2+‐Dependent K+ Channels in Rat Osteoclasts
1997
P2X7 receptor modulation of β-amyloid- and LPS-induced cytokine secretion from human macrophages and microglia
2003
ATP Receptor-Mediated Enhancement of Fast Excitatory Neurotransmitter Release in the Brain
1998
Purinergic receptors: their role in nociception and primary afferent neurotransmission
1996
Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain
2005
P2X3-immunoreactive primary sensory neurons innervating lumbar intervertebral disc in rats
2003
Lack of ATP-evoked GABA and glutamate release in the hippocampus of P2X7 receptor−/− mice
2004
On the immunohistochemical distribution of ionotropic P2X receptors in the nucleus tractus solitarius of the rat
2001
Alteration of dorsal root ganglion P2X 3 receptor expression and function following spinal nerve ligation in the rat
2002
Non‐additive interaction between nicotinic cholinergic and P2X purine receptors in guinea‐pig enteric neurons in culture
1998
ATP‐induced apoptotic cell death in porcine ovarian theca cells through P2X7 receptor activation
2006
In vivo pathway of thermal hyperalgesia by intrathecal administration of α,β‐methylene ATP in mouse spinal cord: Involvement of the glutamate‐NMDA receptor system
1999
The P2X7 purinergic receptor on bovine macrophages mediates mycobacterial death
2001
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
2002 StandoutNature
Microglial-neuronal interactions in synaptic damage and recovery
1999
Co-transmitter function of ATP in central catecholaminergic neurons of the rat
2001
ADP is not an agonist at P2X1 receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets
2000
Purinergic P2 receptors trigger adenosine release leading to adenosine A2A receptor activation and facilitation of long-term potentiation in rat hippocampal slices
2003
Non‐genomic inhibition of human P2X7 purinoceptor by 17β‐oestradiol
1998
Excitatory effect of ATP on acutely dissociated ventromedial hypothalamic neurons of the rat
2001
Neuroprotective effects of inhibiting N-methyl-d-aspartate receptors, P2X receptors and the mitogen-activated protein kinase cascade: A quantitative analysis in organotypical hippocampal slice cultures subjected to oxygen and glucose deprivation
2005
Purinoceptors in neuromuscular transmission
1997
Distribution of P2X1, P2X2, and P2X3 receptor subunits in rat primary afferents: relation to population markers and specific cell types
2000
Endogenous ATP Involvement in Mustard-Oil-Induced Central Sensitization in Trigeminal Subnucleus Caudalis (Medullary Dorsal Horn)
2005
ATP receptors in pain sensation: Involvement of spinal microglia and P2X4 receptors
2005
Expression of purinergic receptors (ionotropic P2X1–7 and metabotropic P2Y1–11) during myeloid differentiation of HL60 cells
2000
Signaling by extracellular nucleotides in anterior pituitary cells
2001
P2 receptors: intracellular signaling
2006
Regulation of bone resorption and formation by purines and pyrimidines
2003
Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
2005
Evidence for P2X3, P2X4, P2X5 but not for P2X7 containing purinergic receptors in Müller cells of the rat retina
2000
Acute nociception mediated by hindpaw P2X receptor activation in the rat
1997
P2X1 Receptor Subunit Contribution to Gating Revealed by a Dominant Negative PKC Mutant
2002
Co‐release of ATP and ACh mediates hypoxic signalling at rat carotid body chemoreceptors
2000
P2X7 receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBCrds mice
2005
Tissue distribution of P2X 4 receptors studied with an ectodomain antibody
2003
Antagonism of ATP responses at P2X receptor subtypes by the pH indicator dye, Phenol red
2005
Prion infection correlates with hypersensitivity of P2X7 nucleotide receptor in a mouse microglial cell line
2007
Intraepithelial Vagal Sensory Nerve Terminals in Rat Pulmonary Neuroepithelial Bodies Express P2X 3 Receptors
2000
The P2Y11 Receptor Mediates the ATP-Induced Maturation of Human Monocyte-Derived Dendritic Cells
2001
Nucleotide receptors: an emerging family of regulatory molecules in blood cells
2001
Activation of Presynaptic P2X7-Like Receptors Depresses Mossy Fiber–CA3 Synaptic Transmission through p38 Mitogen-Activated Protein Kinase
2002
Developmental regulation of integrin expression at the time of implantation in the mouse embryo
1993
Ionic permeability of, and divalent cation effects on, two ATP‐gated cation channels (P2X receptors) expressed in mammalian cells.
1996
Multiple functional P2X and P2Y receptors in the luminal and basolateral membranes of pancreatic duct cells
1999
Neuronal P2X7Receptors Are Targeted to Presynaptic Terminals in the Central and Peripheral Nervous Systems
2001
Functional Consequences of Integrin Gene Mutations in Mice
2001
A Novel Recombinant Plasma Membrane-targeted Luciferase Reveals a New Pathway for ATP Secretion
2005
Expression of the P2X2Receptor Subunit of the ATP-Gated Ion Channel in the Cochlea: Implications for Sound Transduction and Auditory Neurotransmission
1999
Integrin alpha subunit ratios, cytoplasmic domains, and growth factor synergy regulate muscle proliferation and differentiation.
1996
Different Sensitivities to pH of ATP-Induced Currents at Four Cloned P2X Receptors
1997
Role for P2X Receptors in Long-Term Potentiation
2002
The P2X7 Receptor Sustains the Growth of Human Neuroblastoma Cells through a Substance P–Dependent Mechanism
2006
Extracellular ATP Induces a Distorted Maturation of Dendritic Cells and Inhibits Their Capacity to Initiate Th1 Responses
2001
P2 Receptor Modulation of Voltage-gated Potassium Currents in Brown Adipocytes
1999
Cloning and characterization of a functional P2X receptor from larval bullfrog skin
2001
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
Negative Cross Talk between Anionic GABAAand Cationic P2X Ionotropic Receptors of Rat Dorsal Root Ganglion Neurons
2001
Receptors for Purines and Pyrimidines
1998 Standout
Stimulation of P2X7Receptors Elevates Ca2+and Kills Retinal Ganglion Cells
2005
Localization of P2X and P2Y Receptors in Dorsal Root Ganglia of the Cat
2005
P2X7 Receptors in Müller Glial Cells from the Human Retina
2000
ATP stimulation of P2X7 receptors activates three different ionic conductances on cultured mouse Schwann cells
2001
ATP Receptors for the Protection of Hippocampal Functions
1998
Adenosine Triphosphate–Induced Shedding of CD23 and L-Selectin (CD62L) From Lymphocytes Is Mediated by the Same Receptor but Different Metalloproteases
1998
Identification of second messengers that induce expression of functional gap junctions in microglia cultured from newborn rats
2002
Mg2+Inhibition of ATP-Activated Current in Rat Nodose Ganglion Neurons: Evidence That Mg2+Decreases the Agonist Affinity of the Receptor
1997
Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis
2007
Molecular Physiology of P2X Receptors
2002 Standout
ATP Modulation of Excitatory Synapses onto Interneurons
2003
Two types of P2x-purinoceptors in neurons of the guinea pig ileum submucous plexus
1998
Signal transduction from the extracellular matrix.
1993
Norepinephrine Facilitates the Development of the Murine Sweat Response But Is Not Essential
1997
Ca2+Signals Mediated by P2X-Type Purinoceptors in Cultured Cerebellar Purkinje Cells
1998
Transforming Growth Factor β1 (TGF-β1) Promotes Endothelial Cell Survival during In Vitro Angiogenesis via an Autocrine Mechanism Implicating TGF-α Signaling
2001
N-Linked Glycosylation Is Essential for the Functional Expression of the Recombinant P2X2Receptor
1998
Lymphocyte Homing and Homeostasis
1996 StandoutScience
Distinct Roles of P2X Receptors in Modulating Glutamate Release at Different Primary Sensory Synapses in Rat Spinal Cord
2003
Neuroprotective effects of the P2 receptor antagonist PPADS on focal cerebral ischaemia‐induced injury in rats
2006
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Coexpression of P2X3 and P2X2 Receptor Subunits in Varying Amounts Generates Heterogeneous Populations of P2X Receptors That Evoke a Spectrum of Agonist Responses Comparable to That Seen in Sensory Neurons
2001
P2X2 characteristics of the ATP receptor coupled to [Ca2+]i increases in cultured Purkinje neurons from neonatal rat cerebellum
1999
Partial agonists and antagonists reveal a second permeability state of human lymphocyte P2Z/P2X7channel
1998
Maitotoxin and P2Z/P2X7purinergic receptor stimulation activate a common cytolytic pore
1999
Adenosine 5′-Triphosphate: a P2-Purinergic Agonist in the Myocardium
2001
ADP and AMP Induce Interleukin-1β Release from Microglial Cells through Activation of ATP-Primed P2X7 Receptor Channels
2002
Extracellular Nucleotides Differentially Regulate Interleukin-1β Signaling in Primary Human Astrocytes: Implications for Inflammatory Gene Expression
2001
P2X7-like receptor subunits enhance excitatory synaptic transmission at central synapses by presynaptic mechanisms
2004
Single Channel Properties of P2X2 Purinoceptors
1999
Distribution of purinergic P2X receptors in the rat heart
1999
An ATP‐gated cation channel with some P2Z‐like characteristics in gastric smooth muscle cells of toad.
1997
Distinct Localization of P2X Receptors at Excitatory Postsynaptic Specializations
2001
Activation of Microglia by Amyloid β Requires P2X7 Receptor Expression
2009
Astrocyte-Derived ATP Induces Vesicle Shedding and IL-1β Release from Microglia
2005
Maitotoxin activates a nonselective cation channel and a P2Z/P2X7-like cytolytic pore in human skin fibroblasts
1999
Extracellular ATP and TNF-α Synergize in the Activation and Maturation of Human Dendritic Cells
2000
A Domain Contributing to the Ion Channel of ATP-Gated P2X2Receptors Identified by the Substituted Cysteine Accessibility Method
1998
DISTRIBUTION OF P2X RECEPTORS IN THE URINARY BLADDER AND THE URETER OF THE RAT
2000
Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry.
1996
Overview of P2 receptors: Possible functions in immune cells
2001
Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release
1999
Fast structural responses of gap junction membrane domains to AB5 toxins
2013 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Regulation of P2X7 nucleotide receptor function in human monocytes by extracellular ions and receptor density
2001
P2 purinergic receptors on osteoblasts and osteoclasts: Potential targets for drug development
2000
Role of P2X7Receptors in Ischemic and Excitotoxic Brain InjuryIn Vivo
2003
ATP P2X Receptor-Mediated Enhancement of Glutamate Release and Evoked EPSCs in Dorsal Horn Neurons of the Rat Spinal Cord
2001
Synaptic Control of Motoneuronal Excitability
2000
International Union of Pharmacology. XXIV. Current Status of the Nomenclature and Properties of P2X Receptors and Their Subunits
2001
Ca2+-Permeable P2X Receptor Channels in Cultured Rat Retinal Ganglion Cells
1999
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Purinergic control of neuropathic pain
2006
P2X3Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP
2001
Activation of Central Terminal Vanilloid Receptor-1 Receptors and αβ-Methylene-ATP-Sensitive P2X Receptors Reveals a Converged Synaptic Activity onto the Deep Dorsal Horn Neurons of the Spinal Cord
2002
ABC transporter-facilitated ATP conductive transport
1999
ATP Mediates Calcium Signaling Between Astrocytes and Microglial Cells: Modulation by IFN-γ
2001
Exploring and Engineering the Cell Surface Interface
2005 StandoutScience
P2 receptors in cerebellar neurons: Molecular diversity of ionotropic ATP receptors in Purkinje cells
2001
Involvement of P2X2 and P2X3 receptors in neuropathic pain in a mouse model of chronic constriction injury
2003
A novel phospholipase C- and cAMP-independent positive inotropic mechanism via a P2 purinoceptor
1997
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Purinergic stimulation of ciliary activity
2000
Signaling at Purinergic P2X Receptors
2008
P2X RECEPTORS AND THEIR ROLE IN FEMALE IDIOPATHIC DETRUSOR INSTABILITY
2002
Expression of P2X2 and P2X3 receptor subunits in rat carotid body afferent neurones: role in chemosensory signalling
2001
P2X Receptor–Mediated Ionic Currents in Dorsal Root Ganglion Neurons
1999
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Co-localisation of functional nicotinic and ionotropic nucleotide receptors in isolated cholinergic synaptic terminals
2002
Modulation of P2X7 nucleotide receptor expression by pro- and anti-inflammatory stimuli in THP-1 monocytes
1998
Integrin Signaling
1999 StandoutScience
Extracellular Nucleotides Act Through P2X7 Receptors to Activate NF-κB in Osteoclasts
2004
International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits.
2001
P2X7 receptors exert a permissive role on the activation of release-enhancing presynaptic α7 nicotinic receptors co-existing on rat neocortex glutamatergic terminals
2006
P2X Receptors in Trigeminal Subnucleus Caudalis Modulate Central Sensitization in Trigeminal Subnucleus Oralis
2002
Structure−Activity Relationship Studies on a Series of Novel, Substituted 1-Benzyl-5-phenyltetrazole P2X7Antagonists
2006
Differential Modulation by Copper and Zinc of P2X2and P2X4 Receptor Function
1999
Extracellular ATP causes apoptosis and necrosis of cultured mesangial cells via P2Z/P2X7receptors
1998
ATP P2× Receptors and Sensory Synaptic Transmission Between Primary Afferent Fibers and Spinal Dorsal Horn Neurons in Rats
1998
P2X4 purinoceptors mediate an ATP-activated, non-selective cation current in rabbit osteoclasts
1999
Dynamics of ATP-induced Calcium Signaling in Single Mouse Thymocytes
1997
Expression of P2X7 purinoceptors on human lymphocytes and monocytes: evidence for nonfunctional P2X7 receptors
2000
Extracellular nucleotide signaling along the renal epithelium
2001
CHEMICAL ACTIVATORS OF SENSORY NEURONS
1997
Patch–clamp coordinated spectroscopy shows P2X 2 receptor permeability dynamics require cytosolic domain rearrangements but not Panx-1 channels
2008
Allosteric Control of Gating and Kinetics at P2X4Receptor Channels
1999
Domains of P2X receptors involved in desensitization
1996
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Coexpression of Rat P2X2and P2X6Subunits inXenopusOocytes
2000
A QUANTITATIVE ANALYSIS OF PURINOCEPTOR EXPRESSION IN HUMAN FETAL AND ADULT BLADDERS
2001
P2 Receptor Excitation of Rodent Hypoglossal Motoneuron ActivityIn VitroandIn Vivo: A Molecular Physiological Analysis
1997
ATP‐gated cation channels (P2X purinoceptors) in trigeminal mesencephalic nucleus neurons of the rat.
1997
ATP-Induced Killing of VirulentMycobacterium tuberculosisWithin Human Macrophages Requires Phospholipase D
2000
Functional requirement of aquaporin-5 in plasma membranes of sweat glands
2002 StandoutNobel
Bioluminescence detection of ATP release mechanisms in epithelia
1998
Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X 2 -green fluorescent protein receptors
2001
P2X7Receptor and Polykarion Formation
2000
P2X purinoceptors in cultured myenteric neurons of guinea‐pig small intestine.
1996
Increased susceptibility to ATP via alteration of P2X receptor function in dystrophic mdx mouse muscle cells
2006
Adenosine Triphosphate–Induced Shedding of CD23 and L-Selectin (CD62L) From Lymphocytes Is Mediated by the Same Receptor but Different Metalloproteases
1998
ATP Stimulates Sympathetic Transmitter Release via Presynaptic P2X Purinoceptors
1999
CSPα-deficiency causes massive and rapid photoreceptor degeneration
2006 StandoutNobel
Extracellular ATP Activates Transcription Factor NF-κB through the P2Z Purinoreceptor by Selectively Targeting NF-κB p65 (RelA)
1997
ION CHANNELS OF NOCICEPTION
1999
P2X Receptor Trafficking in Neurons Is Subunit Specific
2002
Quantal Release of ATP in Mouse Cortex
2007
A Memory for Extracellular Ca2+by Speeding Recovery of P2X Receptors from Desensitization
1998
Mechanical Allodynia Caused by Intraplantar Injection of P2X Receptor Agonist in Rats: Involvement of Heteromeric P2X2/3Receptor Signaling in Capsaicin-Insensitive Primary Afferent Neurons
2000
The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system
2002
Coordinate Release of ATP and GABA at In VitroSynapses of Lateral Hypothalamic Neurons
2002
Receptors for Purines and Pyrimidines
2012 Standout
P2X7Receptor Modulation on Microglial Cells and Reduction of Brain Infarct Caused by Middle Cerebral Artery Occlusion in Rat
2006
Pharmacology of Cloned P2X Receptors
2000
Neuronal P2X receptors: localisation and functional properties
2000
Neuronal death induced by endogenous extracellular ATP in retinal cholinergic neuron density control
2005
Astrocyte Ca 2+ waves trigger responses in microglial cells in brain slices
2001
Expanding field of purinergic signaling
2001
Purinoceptors: Ontogeny and phylogeny
1996
P2X4 receptors mediate ATP-induced calcium influx in human vascular endothelial cells
2000
Fever in systemic inflammation: roles of purines
2004
Purinergic sensory neurotransmission in the urinary bladder: an in vitro study in the rat
1999
Baculovirus Expression Provides Direct Evidence for Heteromeric Assembly of P2X2and P2X3Receptors
1997
Brilliant Blue G Selectively Blocks ATP-Gated Rat P2X7Receptors
2000
Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages
2007
Distribution of the P2X2 receptor subunit of the ATP-gated ion channels in the rat central nervous system
1999
A Pyridoxine Cyclic Phosphate and Its 6-Azoaryl Derivative Selectively Potentiate and Antagonize Activation of P2X1 Receptors
1998
P2X7Receptor Activation–Induced Contraction and Lysis in Human Saphenous Vein Smooth Muscle
1998
P2X4: an ATP-activated ionotropic receptor cloned from rat brain.
1996
Purinoceptors on Neuroglia
2009
The Proinflammatory Action of Microglial P2 Receptors Is Enhanced in SOD1 Models for Amyotrophic Lateral Sclerosis
2009
Autoradiography of [3H]α,β-methylene-ATP binding sites in medulla oblongata and spinal cord of the rat
1997
A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method.
1998
Microglia at brain stab wounds express connexin 43 andin vitroform functional gap junctions after treatment with interferon-γ and tumor necrosis factor-α
2001
Cellular Distribution of the P2X4 ATP Receptor mRNA in the Brain and Non-Neuronal Organs of Rats.
1996
Nucleotides regulate NaCl transport in mIMCD-K2 cells via P2X and P2Y purinergic receptors
1999
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro
2002
Neuronal Plasticity: Increasing the Gain in Pain
2000 StandoutScience
Extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells
2002
Exacerbation of Experimental Autoimmune Encephalomyelitis in P2X7R−/− Mice: Evidence for Loss of Apoptotic Activity in Lymphocytes
2006
The Cytolytic P 2Z Receptor for Extracellular ATP Identified as a P 2X Receptor (P2X 7 )
1996 StandoutScience
The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release
2000
Expression of a P2X7 Receptor by a Subpopulation of Human Osteoblasts
2001
Diverse Signal Transduction Pathways Mediated by Endogenous P2Receptors in Cultured Rat Cerebral Cortical Neurons
1998
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor
2001 StandoutNobel
Salivary Gland P2 Nucleotide Receptors
1999
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
ATP P2XReceptors Mediate Fast Synaptic Transmission in the Dorsal Horn of the Rat Spinal Cord
1997
Kinetics and Mechanism of ATP-Dependent IL-1β Release from Microglial Cells
2000
Purinergic P2X7 receptor function in lung alveolar macrophages: Pharmacologic characterization and bidirectional regulation by Th1 and Th2 cytokines
2003
Action Potential-Independent Release of Glutamate by Ca2+Entry through Presynaptic P2X Receptors Elicits Postsynaptic Firing in the Brainstem Autonomic Network
2004
Properties of the Novel ATP-Gated Ionotropic Receptor Composed of the P2X1 and P2X5 Isoforms
1999
Calcium Flux Through Predominantly Independent Purinergic ATP and Nicotinic Acetylcholine Receptors
1997
Cloned P2X receptor subunits in cerebellum and hippocampus
2001
Physiology of Microglia
2011 Standout
Presynaptic P2X Receptors Facilitate Inhibitory GABAergic Transmission between Cultured Rat Spinal Cord Dorsal Horn Neurons
2000
Functional and molecular evidence for P2X receptors in LLC-PK1cells
1998
Upregulation of the Enzyme Chain Hydrolyzing Extracellular ATP after Transient Forebrain Ischemia in the Rat
1998
P2X Receptors and Nociception
2001
Modulation of the Affinity of Integrin α IIb β 3 (GPIIb-IIIa) by the Cytoplasmic Domain of α IIb
1991 Science
Central P2X4and P2X6Channel Subunits Coassemble into a Novel Heteromeric ATP Receptor
1998
Localization of P2X1purinoceptors by autoradiography and immunohistochemistry in rat kidneys
1998
Maitotoxin Induces Biphasic Interleukin-1β Secretion and Membrane Blebbing in Murine Macrophages
2004
Apical regulation of nonselective cation channels by ATP in larval bullfrog skin
1997
SIGNALING BY EXTRACELLULAR NUCLEOTIDES
1996 StandoutNobel
Works of Ginetta Collo being referenced
Mouse Dendritic Cells Express the P2X7 Purinergic Receptor: Characterization and Possible Participation in Antigen Presentation
1999
ATP-mediated cytotoxicity in microglial cells
1997
Distinct α7Aβ1 and α7Bβ1 integrin expression patterns during mouse development: α7A is restricted to skeletal muscle but α7B is expressed in striated muscle, vasculature, and nervous system
1996
Tissue distribution of the P2X7 receptor
1997
The Permeabilizing ATP Receptor, P2X7
1997
P2X Receptors: An Emerging Channel Family
1996
Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.
1991
An antagonist-insensitive P2X receptor expressed in epithelia and brain.
1996
Endothelial cell integrin α5β1 expression is modulated by cytokines and during migration in vitro
1999
P2X1 receptor activation in HL60 cells
1996
A new isoform of the laminin receptor integrin alpha 7 beta 1 is developmentally regulated in skeletal muscle.
1993
Blockade of Human P2X7 Receptor Function With a Monoclonal Antibody
1998
Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels
1996
Spontaneous Cell Fusion in Macrophage Cultures Expressing High Levels of the P2Z/P2X7 Receptor
1997
Blockade of Human P2X7 Receptor Function With a Monoclonal Antibody
1998