Citation Impact
Citing Papers
Chromosomal Instability Confers Intrinsic Multidrug Resistance
2011
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Statistical significance for genomewide studies
2003 Standout
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
2007 StandoutNobel
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
Human Mismatch Repair
2005 StandoutNobel
Mispair-specific Recruitment of the Mlh1-Pms1 Complex Identifies Repair Substrates of the Saccharomyces cerevisiae Msh2-Msh3 Complex
2014
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
2000
GENOMIC INSTABILITY IN COLORECTAL CARCINOMAS: COMPARISON OF DIFFERENT EVALUATION METHODS AND THEIR BIOLOGICAL SIGNIFICANCE
1996
Distinct MutS DNA-binding Modes That Are Differentially Modulated by ATP Binding and Hydrolysis
2001 StandoutNobel
Replication Protein A Confers Structure-specific Endonuclease Activities to the XPF-ERCC1 and XPG Subunits of Human DNA Repair Excision Nuclease
1996 StandoutNobel
Strand-specific Mismatch Repair in Mammalian Cells
1997 StandoutNobel
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
1995
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
MutS homologs in mammalian cells
1997
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
1998
DNA‐replication Fidelity, Mismatch Repair and Genome Instability in Cancer Cells
1996
Genetic instabilities in human cancers
1998 StandoutNature
Molecular Predictors of Survival after Adjuvant Chemotherapy for Colon Cancer
2001
Hydrolytic function of Exo1 in mammalian mismatch repair
2014 StandoutNobel
Microsatellite Instability and 8p Allelic Imbalance in Stage B2 and C Colorectal Cancers
1999
Mismatch-, MutS-, MutL-, and Helicase II-dependent Unwinding from the Single-strand Break of an Incised Heteroduplex
1998 StandoutNobel
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
MutS and MutL Activate DNA Helicase II in a Mismatch-dependent Manner
1998 StandoutNobel
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
2002 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Mouse models for colorectal cancer
1999
The Molecular Basis of Turcot's Syndrome
1995
DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro
1997 StandoutNobel
Tumor Microsatellite Instability and Clinical Outcome in Young Patients with Colorectal Cancer
2000
Mutations Predisposing to Hereditary Nonpolyposis Colorectal Cancer
1997
Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
2000
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Genetic instability in colorectal cancers
1997 StandoutNature
Genetic alterations in breast cancer
1995
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
1994
Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer
2000
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Determination of microsatellite instability,p53 and K-RAS mutations in hepatic metastases from patients with colorectal cancer: Relationship with response to 5-fluorouracil and survival
2001
Microsatellite Instability in Human Cancer: A Prognostic Marker for Chemotherapy?
1999
Tumour budding in colorectal carcinoma
2006
Cisplatin and Adriamycin Resistance Are Associated with MutLα and Mismatch Repair Deficiency in an Ovarian Tumor Cell Line
1996 StandoutNobel
Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
1998 StandoutNobel
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
Molecular basis of HNPCC: Mutations of MMR genes
1997
Prognostic Significance of DNA Replication Errors in Young Patients With Colorectal Cancer
1998
DNA mismatch repair and cancer
2001
Meiotic Pachytene Arrest in MLH1-Deficient Mice
1996
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
1996
DNA Mismatch Repair-dependent Response to Fluoropyrimidine-generated Damage
2004
DNA Repair Excision Nuclease Attacks Undamaged DNA
2001 StandoutNobel
The MutL ATPase Is Required for Mismatch Repair
2000 StandoutNobel
DNA Chain Length Dependence of Formation and Dynamics of hMutSα·hMutLα·Heteroduplex Complexes
2001 StandoutNobel
High Prevalence of Activated Intraepithelial Cytotoxic T Lymphocytes and Increased Neoplastic Cell Apoptosis in Colorectal Carcinomas with Microsatellite Instability
1999
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
ASCO 2006 Update of Recommendations for the Use of Tumor Markers in Gastrointestinal Cancer
2006
Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer
2003
Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells
2003
Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes.
1996
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.
1994
Microsatellite instability: marker of a mutator phenotype in cancer.
1994
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
APC mutations in colorectal tumors with mismatch repair deficiency.
1996
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
1996
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
DNA Loop Repair by Human Cell Extracts
1994 Science
Requirement of the Yeast RTH1 5′ to 3′ Exonuclease for the Stability of Simple Repetitive DNA
1995 Science
Low-level microsatellite instability in most colorectal carcinomas.
2002
Cancer Cell Cycles
1996 StandoutScience
MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast
1994 Science
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
MSH2 andMLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis
1997
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.
1999
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability.
2003
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
1998 Standout
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.
1996
exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair
2001
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.
1998
Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis
2005
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
1995 StandoutNobel
Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer
2000
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.
1997
Genetic susceptibility to non-polyposis colorectal cancer
1999
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.
1998 Standout
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH 2 gene
1999
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.
1994
Mismatch Repair, Genetic Stability, and Cancer
1994 StandoutScienceNobel
Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes
1996 Science
Biochemistry and genetics of eukaryotic mismatch repair.
1996
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
Works of GI Meling being referenced
APC and CTNNB1 Mutations in a Large Series of Sporadic Colorectal Carcinomas Stratified by the Microsatellite Instability Status
2002
Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history.
1993
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas
1995
Strong HLA-DR expression in large bowel carcinomas is associated with good prognosis
1993