Citation Impact
Citing Papers
Polo-like Kinase 1 Facilitates Loss of Pten Tumor Suppressor-induced Prostate Cancer Formation
2011
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
International Union of Pharmacology nomenclature of adrenoceptors.
1994 StandoutNobel
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
Cardiovascular and Metabolic Alterations in Mice Lacking Both β1- and β2-Adrenergic Receptors
1999 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Molecular biology of α-adrenergic receptors: implications for receptor classification and for structure-function relationships
1991 StandoutNobel
α1-Adrenergic Receptors Positively Regulate Toll-Like Receptor Cytokine Production from Human Monocytes and Macrophages
2011
Gene Substitution/Knockout to Delineate the Role of α2‐Adrenoceptor Subtypes in Mediating Central Effects of Catecholamines and Imidazolines
1999 StandoutNobel
(+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of α1-adrenoceptors
1989
Therapeutic potential of resveratrol: the in vivo evidence
2006 Standout
CD44: a validated target for improved delivery of cancer therapeutics
2012
Combined cancer therapy with hyaluronan-decorated fullerene-silica multifunctional nanoparticles to target cancer stem-like cells
2016
The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin
2005 Standout
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Affinity of different α1-agonists and antagonists for the α1-adrenoceptors of rabbit and rat liver membranes
1993
A Randomized, Open-Label Phase II Trial of Volasertib as Monotherapy and in Combination With Standard-Dose Pemetrexed Compared With Pemetrexed Monotherapy in Second-Line Treatment for Non–Small-Cell Lung Cancer
2015
The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics
2013
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
2007 Standout
Metadata Standard and Data Exchange Specifications to Describe, Model, and Integrate Complex and Diverse High-Throughput Screening Data from the Library of Integrated Network-based Cellular Signatures (LINCS)
2014
Costimulation of Adenylyl Cyclase and Phospholipase C by a Mutantα1B-Adrenergic Receptor Transgene Promotes Malignant Transformation of Thyroid Follicular Cells1
1997 StandoutNobel
Modulation of oxidative stress as an anticancer strategy
2013 Standout
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity
2019 StandoutNobel
Transgenic Mice with Cardiac Overexpression of α1B-Adrenergic Receptors
1997 StandoutNobel
Effect of chronic lithium treatment on the turnover of α2-adrenoceptors after chemical inactivation in rats
2004
Targeting cancer-initiating cell drug-resistance: a roadmap to a new-generation of cancer therapies?
2011
Cardiac α1-Adrenoceptors that regulate contractile function: Subtypes and subcellular signal transduction mechanismsthat regulate contractile function: Subtypes and subcellular signal transduction mechanisms
1996
Agonist Regulation of α1B-Adrenergic Receptor Subcellular Distribution and Function
1995
Expression patterns of the regulatory proteins G protein‐coupled receptor kinase 2 and β‐arrestin 1 during rat postnatal brain development
2000
Stress signalling pathways that impair prefrontal cortex structure and function
2009 Standout
Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53
2013
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
The road less traveled: modulating signal transduction enzymes by inhibiting their protein–protein interactions
2009
Effect of Eculizumab on Hemolysis and Transfusion Requirements in Patients with Paroxysmal Nocturnal Hemoglobinuria
2004
Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugates
2016
α-Adrenoceptors
1994
Inositol Lipids and Signal Transduction in the Nervous System: An Update
1992
Rheumatoid arthritis
2010 Standout
Tripartite synapses: glia, the unacknowledged partner
1999 Standout
Strategies and challenges for the next generation of antibody–drug conjugates
2017 Standout
Genetic alteration of the α2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels
1999 StandoutNobel
The ChEMBL database in 2017
2016 Standout
Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling
2001 StandoutNobel
CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?
2011
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Neuronal Calcium Signaling
1998 Standout
Expression of α1 adrenergic receptor subtype mRNAs in the rat cardiovascular system with aging
1996
The functions and regulation of the PTEN tumour suppressor
2012 Standout
α1B-Adrenoceptor-mediated stimulation of Ca2+ mobilization and cAMP accumulation in isolated rat hepatocytes
1993
Regional and laminar distributions of α1-adrenoceptors and their subtypes in human and rat hippocampus
1991
A role for norepinephrine in stress-induced cognitive deficits: α-1-adrenoceptor mediation in the prefrontal cortex
1999
Subtypes of .ALPHA.1-Adrenoceptors Involved in Noradrenaline-Induced Contractions of Rat Thoracic Aorta and Dog Carotid Artery.
1991
ERK Plays a Regulatory Role in Induction of LTP by Theta Frequency Stimulation and Its Modulation by β-Adrenergic Receptors
1999 StandoutNobel
Genetic Alteration of α2C-Adrenoceptor Expression in Mice: Influence on Locomotor, Hypothermic, and Neurochemical Effects of Dexmedetomidine, a Subtype-Nonselective α2-Adrenoceptor Agonist
1997 StandoutNobel
Cardiac excitation–contraction coupling
2002 StandoutNature
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
2005 Standout
Human ATP-Binding Cassette Transporter ABCB1 Confers Resistance to Volasertib (BI 6727), a Selective Inhibitor of Polo-like Kinase 1
2015
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
1993
Reduced Reperfusion–Induced Ins(1,4,5)P3Generation and Arrhythmias in Hearts Expressing Constitutively Active α1B-Adrenergic Receptors
1998
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Functional Consequences of Altering Myocardial Adrenergic Receptor Signaling
2000 StandoutNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Advances and Advantages of Nanomedicine in the Pharmacological Targeting of Hyaluronan-CD44 Interactions and Signaling in Cancer
2014
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Mutation of the α2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine
2002 StandoutNobel
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Distribution of α1-Adrenergic Receptor mRNA Species in Rat Heart
1998
Transgenic Manipulation of Myocardial G Protein–Coupled Receptors and Receptor Kinases
1996 StandoutNobel
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
Modulation of receptor-mediated inositol phospholipid breakdown in the brain
1991
Identification, Quantification, and Localization of mRNA for Three Distinct Alpha1Adrenergic Receptor Subtypes in Human Prostate
1993 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION
1998 StandoutNobel
Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation
2008
Hybrid Transgenic Mice Reveal In Vivo Specificity of G Protein–Coupled Receptor Kinases in the Heart
2000 StandoutNobel
alpha 1-adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C.
1994
Works of Gertraud Hanft being referenced
The Efficacy and Safety of BI 2536, a Novel Plk-1 Inhibitor, in Patients with Stage IIIB/IV Non-small Cell Lung Cancer Who Had Relapsed after, or Failed, Chemotherapy: Results from an Open-Label, Randomized Phase II Clinical Trial
2010
Radioligand binding studies of α1‐adrenoceptor subtypes in rat heart
1994
Demonstration of α1A-and α1B-adrenoceptor binding sites in human brain tissue
1989
Meloxicam oral suspension: a treatment alternative to solid meloxicam formulations
2001
Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)
2010
Safety, biodistribution, pharmacokinetics, and immunogenicity of 99m Tc-labeled humanized monoclonal antibody BIWA 4 (bivatuzumab) in patients with squamous cell carcinoma of the head and neck
2003
Effect of chronic lithium administration on adrenoceptor binding and adrenoceptor regulation in rat cerebral cortex
1988
Does lithium in vitro and ex vivo alter the release of [3H]noradrenaline from brain tissue and the sensitivity of presynaptic autoreceptors?
1990
Subclassification of α1‐adrenoceptor recognition sites by urapidil derivatives and other selective antagonists
1989
5-Methyl-urapidil discriminates between subtypes of the α1-adrenoceptor
1988
Phase I trial with the CD44v6-targeting immunoconjugate bivatuzumab mertansine in head and neck squamous cell carcinoma
2008
Functional studies on α1‐adrenoceptor subtypes mediating inotropic effects in rat right ventricle
1994
Safety and pharmacokinetics of bivatuzumab mertansine in patients with CD44v6-positive metastatic breast cancer: final results of a phase I study
2007
?1B- but not ?1A-adrenoceptors mediate inositol phosphate generation
1990
Efficacy and safety of meloxicam in patients with rheumatoid arthritis.
1997
α1-Adrenoceptors: the ability of various agonists and antagonists to discriminate between two distinct [3H]prazosin binding sites
1989
Urapidil Analogues Are Potent Ligands of the 5-HT1A Receptor
1990
Randomized phase II trial of two dosing schedules of BI 2536, a novel Plk-1 inhibitor, in patients with relapsed advanced or metastatic non-small-cell lung cancer (NSCLC)
2008
The effect of reserpine, desipramine and thyroid hormone on alpha 1a‐ and alpha 1b‐adrenoceptor binding sites: evidence for a subtype‐ specific regulation.
1990
Urapidil Analogues Are Potent Ligands of the 5-HT1A Receptor
1990
Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for ?1-adrenoceptor binding sites
1987