Citation Impact
Citing Papers
Structure of the Rotor of the V-Type Na + -ATPase from Enterococcus hirae
2005 ScienceNobel
IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice.
1999
Induction of CD4+ T Cell Alloantigen-Specific Hyporesponsiveness by IL-10 and TGF-β
1999
Interleukin-12: A Cytokine at the Interface of Inflammation and Immunity
1998
Functional diversity of helper T lymphocytes
1996 StandoutNature
Endocytosis
1989
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Vacuolar proton pumps
1989
Differential requirement of CD28 for IL-12 receptor expression and function in CD4+ and CD8+ T cells
2001
Interleukin-12 and the regulation of innate resistance and adaptive immunity
2003 Standout
Regulatory T Cells
2000 StandoutNobel
Interleukin-12 in anti-tumor immunity and immunotherapy
2002
The Arabidopsis det3 mutant reveals a central role for the vacuolar H+-ATPase in plant growth and development
1999
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β
1995
Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets
1998
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
1988 StandoutNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice
1995
The Role of CTLA‐4 in the Regulation and Initiation of T‐Cell Responses
1996 StandoutNobel
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Interleukin‐12 and B7.1 co‐stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors
1996
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
1993 StandoutNatureNobel
Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-β
1996
Annexin VI is required for budding of clathrin-coated pits
1992 StandoutNobel
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Autophagy and related mechanisms of lysosome-mediated protein degradation
1994
IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses
1996
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Clathrin, Adaptors, and Sorting
1990
Cell Selection by Antigen in the Immune Response
1969 StandoutNobel
Cutting Edge: IL-12 Is Required for the Maintenance of IFN-γ Production in T Cells Mediating Chronic Resistance to the Intracellular Pathogen, Toxoplasma gondii
2000
Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance
1986 StandoutScienceNobel
Dependence of the chemical nature of antibodies on the net electrical charge of antigens.
1966
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1997 StandoutNobel
Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors.
1995
Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis
1998
Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole.
1996 StandoutNobel
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.
1995
Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.
1988 Standout
PHAGOCYTOSIS OF THE ANTIGEN, A CRUCIAL STEP IN THE INDUCTION OF THE PRIMARY RESPONSE
1965 StandoutNobel
CTLA-4 blockade synergizes with tumor-derived granulocyte– macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
1998 StandoutNobel
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
1996 Standout
A functional interleukin 12 receptor complex is composed of two β-type cytokine receptor subunits
1996
The fungal vacuole: composition, function, and biogenesis
1990
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
Analysis of Autoimmunity through Experimental Models of Thyroiditis and Allergic Encephalomyelitis
1980
IL-12, But Not IFN-γ, Plays a Major Role in Sustaining the Chronic Phase of Colitis in IL-10-Deficient Mice
1998
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
1995 StandoutNobel
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Functional Specificity of Thymus-Dependent Lymphocytes
1977 StandoutScienceNobel
Mice Lacking Bioactive IL-12 Can Generate Protective, Antigen-Specific Cellular Responses to Mycobacterial Infection Only if the IL-12 p40 Subunit Is Present
2002
Living with Clathrin: Its Role in Intracellular Membrane Traffic
1988 Science
T Cell Control of Antibody Production
1974
Reversibility of T helper 1 and 2 populations is lost after long-term stimulation.
1996
T cell genetic background determines default T helper phenotype development in vitro.
1995
IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice.
1998
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Isolation of genes encoding the Neurospora vacuolar ATPase. Analysis of vma-2 encoding the 57-kDa polypeptide and comparison to vma-1.
1988
IL-12 Is Dysregulated in Macrophages from IRF-1 and IRF-2 Knockout Mice
1999
The Inverse Association Between Tuberculin Responses and Atopic Disorder
1997 Science
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.
1995
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Induction of Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Restricts Clonal Expansion of Helper T Cells
2001
Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells.
1994
Pregnant mice are not primed but can be primed to fetal alloantigens.
1979
IL-12 Is Required to Maintain a Th1 Response DuringLeishmania majorInfection
2000
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
The cDNA sequence of the 69-kDa subunit of the carrot vacuolar H+-ATPase. Homology to the beta-chain of F0F1-ATPases.
1988
Distribution of horseradish peroxidase (HRP)-anti-HRP immune complexes in mouse spleen with special reference to follicular dendritic cells.
1978 StandoutNobel
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Immunological Unresponsiveness
1973
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone
1984 StandoutNatureNobel
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
1998 StandoutNobel
The role of the L3T4 molecule in mitogen and antigen-activated signal transduction
1987
Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
1989 StandoutScienceNobel
Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10.
1996
Genetic control of lipopolysaccharide induced generation of serum colony stimulating factor and proliferation of splenic granulocyte/macrophage precursor cells
1976
Alteration of Stimulus-Specific Guard Cell Calcium Oscillations and Stomatal Closing in Arabidopsis det3 Mutant
2000 StandoutScienceNobel
Biochemical characterization of the yeast vacuolar H+-ATPase
1989
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta.
1999
Dissociation, cross-linking, and glycosylation of the coated vesicle proton pump.
1990
The Biology and Detection of Immune Complexes
1980
High Purity Preparations of Higher Plant Vacuolar H+-ATPase Reveal Additional Subunits
1989
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
A perspective of the binding change mechanism for ATP synthesis 1
1989 StandoutNobel
Structure of the 116-kDa polypeptide of the clathrin-coated vesicle/synaptic vesicle proton pump
1991 StandoutNobel
Regulatory Effect of Antibody on the Immune Response
1968
Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production.
1995
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations.
1995
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
1999 StandoutNobel
Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1
1994 StandoutNobel
Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen.
1962
Works of Geronimo Terres being referenced
Subunit composition and ATP site labeling of the coated vesicle proton-translocating adenosine triphosphatase
1987
Bee venom phospholipase A2‐specific T cell clones from human allergic and non‐allergic individuals: cytokine patterns change in response to the antigen concentration
1992
Topography and subunit stoichiometry of the coated vesicle proton pump.
1988
A Quantitative Difference in the Immune Response between Male and Female Mice
1968
Enhanced immunological sensitization of mice by the simultaneous injection of antigen and specific antiserum. I. Effect of varying the amount of antigen used relative to the antiserum.
1961
Specificity of Enhanced Immunological Sensitization of Mice Following Injections of Antigens and Specific Antisera.
1962
Enhanced Immunologic Sensitization of Mice by the Simultaneous Injection of Antigen and Specific Antiserum
1966
Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells.
1986
Enhanced Sensitization in Mice by Simultaneous Injection of Antigen and Specific Rabbit Antiserum.
1959
Enhanced Immunological Sensitization of Mice by the Simultaneous Injection of Antigen and Specific Antiserum
1961
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.
1994
Enhanced immunologic sensitization of mice by the simultaneous injection of antigen and specific antiserum. II. Effect of varying the antigen-antibody ratio and the amount of immune complex injected.
1966
Acquired Immune Tolerance in Mice to Crystalline Bovine Serum Albumin,
1959
Appearance of an Early “Primed State” in Mice following the Concomitant Injections of Antigen and Specific Antiserum
1972
Antibody-Induced Killing in Vivo of L1210/MTX-R Cells Quantitated in Passively Immunized Mice with 131I-Iododeoxyuridine-Labeled Cells and Whole-Body Measurement of Retained Radioactivity
1976
Immunolocalization of the vacuolar-type (H+)-ATPase from clathrin-coated vesicles.
1991