Citation Impact
Citing Papers
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
2009 StandoutScience
Epigenetic regulation of the alternatively activated macrophage phenotype
2009
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of l -Arginine Metabolism
2001
Alternative Metabolic States in Murine Macrophages Reflected by the Nitric Oxide Synthase/Arginase Balance: Competitive Regulation by CD4+ T Cells Correlates with Th1/Th2 Phenotype
1998
IL-13 Induces Disease-Promoting Type 2 Cytokines, Alternatively Activated Macrophages and Allergic Inflammation during Pulmonary Infection of Mice with Cryptococcus neoformans
2007
Francisella tularensis Live Vaccine Strain Induces Macrophage Alternative Activation as a Survival Mechanism
2008
IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype
2002
Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation
2012
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages
2000 Nature
Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways
2012
Alternative versus classical macrophage activation during experimental African trypanosomosis
2001
Alternative M2 Activation of Kupffer Cells by PPARδ Ameliorates Obesity-Induced Insulin Resistance
2008
Inflammation and cancer
2002 StandoutNature
Comparison of Progressive Cortical Gray Matter Loss in Childhood-OnsetSchizophrenia With That in Childhood-Onset Atypical Psychoses
2004
M1 and M2 Macrophages: Oracles of Health and Disease
2012
Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro
2003
Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens
2008
Metabolic Reprogramming of Immune Cells in Cancer Progression
2015
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
2006 StandoutNature
Allergic airway disease is unaffected by the absence of IL-4Rα–dependent alternatively activated macrophages
2012
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis
2011
Amino acid auxotrophy as a system of immunological control nodes
2016
Macrophages: Master Regulators of Inflammation and Fibrosis
2010 Standout
Nitric oxide synthases: Roles, tolls, and controls
1994 Standout
Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor That Modulates Circadian Gene Expression
2014 StandoutNobel
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1
2006
Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells
2008
Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells
2008
Tissue-based class control: the other side of tolerance
2011
Autophagy: Renovation of Cells and Tissues
2011 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection
2016
Effective clearance of intracellular Leishmania majorin vivo requires Pten in macrophages
2008 StandoutNobel
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
TH2 Cytokines and Allergic Challenge Induce Ym1 Expression in Macrophages by a STAT6-dependent Mechanism
2002
The Transcription Factor NFAT3 Mediates Neuronal Survival
2004
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis
2003
Dual biological effects of the cytokines interleukin-10 and interferon-γ
2011
Upregulation of Arginase Expression in Wound-Derived Fibroblasts
2002
Circadian Orchestration of the Hepatic Proteome
2006
Inhibition of arginase in rat and rabbit alveolar macrophages by Nω‐hydroxy‐D ,L ‐indospicine, effects on L ‐arginine utilization by nitric oxide synthase
1997
Fibrotic disease and the TH1/TH2 paradigm
2004 Standout
Inflammatory cell infiltration of tumors: Jekyll or Hyde
2007
Arginase I induction in macrophages, triggered by Th2‐type cytokines, supports the growth of intracellular Leishmania parasites
2002
The development of allergic inflammation
2008 StandoutNature
Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation
2006
Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages
2008
Redox signaling: Nitrosylation and related target interactions of nitric oxide
1994
Rethinking schizophrenia
2010 StandoutNature
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
2009
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
Targeting Tumor-Associated Macrophages and Inhibition of MCP-1 Reduce Angiogenesis and Tumor Growth in a Human Melanoma Xenograft
2007
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Origin and physiological roles of inflammation
2008 StandoutNature
Comparative properties of arginases
1996
Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact
2000
LC3-Associated Phagocytosis and Inflammation
2017
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The Hallmarks of Aging
2013 Standout
Points of control in inflammation
2002 StandoutNature
Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology
2004
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Regulation of immune responses by L-arginine metabolism
2005
Alternatively activated macrophages in protozoan infections
2007
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
SHIP Represses the Generation of Alternatively Activated Macrophages
2005
Exploring the full spectrum of macrophage activation
2008 Standout
Alternative activation of macrophages
2003 Standout
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
2007 Standout
Macrophage activation and polarization
2007 Standout
The immunobiology of schistosomiasis
2002 Standout
Inflammasomes in health and disease
2012 StandoutNature
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
Local Arginase 1 Activity Is Required for Cutaneous Wound Healing
2013
Myeloid-Specific Disruption of Tyrosine Phosphatase Shp2 Promotes Alternative Activation of Macrophages and Predisposes Mice to Pulmonary Fibrosis
2014
Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
2008
STAT1 Is Essential for Antimicrobial Effector Function but Dispensable for Gamma Interferon Production duringToxoplasma gondiiInfection
2004
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP
2002 StandoutNobel
Global Gene Expression Profiles During Acute Pathogen-Induced Pulmonary Inflammation Reveal Divergent Roles for Th1 and Th2 Responses in Tissue Repair
2003
Macrophage Polarization
2016 Standout
Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging
2011 Science
Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease
2005
Biochemical and functional characterization of three activated macrophage populations
2006
Regulation and Function of the Interleukin 13 Receptor α 2 During a T Helper Cell Type 2–dominant Immune Response
2003
The many faces of macrophage activation
2003
Nitric oxide and the immune response
2001 Standout
M-1/M-2 Macrophages and the Th1/Th2 Paradigm
2000 Standout
Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling
2010
The Pathogenesis of Schistosomiasis Is Controlled by Cooperating IL-10-Producing Innate Effector and Regulatory T Cells
2004
Shaping Gene Expression in Activated and Resting Primary Macrophages by IL-10
2002
Obstacles and opportunities for understanding macrophage polarization
2011
Pattern of Macrophage Activation in Yersinia‐Resistant and Yersinia‐Susceptible Strains of Mice
2007
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production
2001
2000
Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses
2014
Spermidine in health and disease
2018 StandoutScience
Metabolism of agmatine in macrophages: modulation by lipopolysaccharide and inhibitory cytokines
1998
Disease Tolerance as a Defense Strategy
2012 StandoutScience
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Toll-Like Receptor 4 Contributes to Efficient Control of Infection with the Protozoan ParasiteLeishmania major
2004
Alternative versus classical macrophage activation during experimental African trypanosomosis
2001
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent
2004
Exosomes as drug delivery vehicles for Parkinson's disease therapy
2015 Standout
Induction of Intracellular Arginase Activity Does not Diminish the Capacity of Macrophages to Produce Nitric Oxide in vitro
1999
Blockade of Myeloid-Derived Suppressor Cells after Induction of Lymphopenia Improves Adoptive T Cell Therapy in a Murine Model of Melanoma
2012
Arginase modulates nitric oxide production in activated macrophages
1998
New insights into the regulation of inducible nitric oxide synthesis
1994
The Inhibition of Arginase by Nω-Hydroxy-l -Arginine Controls the Growth of Leishmania Inside Macrophages
2001
Enhancer-Mediated Control of Macrophage-Specific Arginase I Expression
2004
Differential regulation of macrophage arginine metabolism: a proposed role in wound healing
1997
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas
2014
Arginine metabolism: nitric oxide and beyond
1998 Standout
PROTEASES IN PARASITIC DISEASES
2006
Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.
2001
Impairment of Alternative Macrophage Activation Delays Cutaneous Leishmaniasis in Nonhealing BALB/c Mice
2006
Works of Germán Soler being referenced
Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells
1999
Parallel Induction of Nitric Oxide and Glucose-6-Phosphate Dehydrogenase in Activated Bone Marrow Derived Macrophages
1993
Involvement of protein kinase A in the induction of arginase in murine bone marrow-derived macrophages
1997
Determination of arginase activity in macrophages: a micromethod
1994
Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants
2004
Trypsin digestion of arginase: Evidence for a stable conformation manganese directed
1992
Kinetics of manganese reconstitution and thiol group exposition in dialyzed rat mammary gland arginase
1994
Lithium inhibits caspase 3 activation and dephosphorylation of PKB and GSK3 induced by K+deprivation in cerebellar granule cells
2001
Different mechanisms of protection against apoptosis by valproate and Li+
1999
Arginine catabolism in the phototrophic bacterium Rhodobacter capsulatus E1F1
1992
Oxidation of NG‐hydroxyl‐l ‐arginine to nitric oxide mediated by respiratory burst: an alternative pathway to NO synthesis
1997
Arginase Induction by Suppressors of Nitric Oxide Synthesis (IL-4, IL-10 and PGE2) in Murine Bone-Marrow-Derived Macrophages
1995
Implications of the S-shaped domain in the quaternary structure of human arginase
2000
Silencing DJ‐1 reveals its contribution in paraquat‐induced autophagy
2009
Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow‐derived macrophages by TH 1 and TH 2 cytokines
1995
Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy
2007
Inhibition of Paraquat-Induced Autophagy Accelerates the Apoptotic Cell Death in Neuroblastoma SH-SY5Y Cells
2007
Immunological Identity of the Two Different Molecular Mass Constltutive Subunits of Liver Arginase
1994
Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo
2005
Circadian rhythms in enzymatic activity of rat liver arginase and glucose 6-phosphate dehydrogenase.
1989
Physico-chemical properties of hepatocyte plasma-membrane-bound arginase.
1991