Citation Impact
Citing Papers
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Signaling from β1- and β2-adrenergic receptors is defined by differential interactions with PDE4
2008 StandoutNobel
A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons
2017 StandoutNobel
Synapses and Alzheimer's Disease
2012 StandoutNobel
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
2011 Standout
Ferroptosis: Death by Lipid Peroxidation
2015 Standout
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
2005 Standout
The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents
2008
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use
2006 Standout
cGMP Signalling in the Mammalian Brain: Role in Synaptic Plasticity and Behaviour
2008
Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?
2016 Standout
Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
2005
Excitotoxicity: Bridge to various triggers in neurodegenerative disorders
2012
Expression of the cGMP‐specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains
2007
Neuroanatomical and Neurochemical Substrates of Timing
2010 Standout
Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels
2005
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Reversal of Oxidative Stress-Induced Anxiety by Inhibition of Phosphodiesterase-2 in Mice
2008
Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders
2016
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
The role of phosphodiesterase isoforms 2, 5, and 9 in the regulation of NO-dependent and NO-independent cGMP production in the rat cervical spinal cord
2006
SOCE in neurons: Signaling or just refilling?
2015
Selective blockade of phosphodiesterase types 2, 5 and 9 results in cyclic 3'5' guanosine monophosphate accumulation in retinal pigment epithelium cells
2006
Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy
2016 Standout
The use of spirocyclic scaffolds in drug discovery
2014 Standout
Choline: an essential nutrient for public health
2009 Standout
Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
2011 StandoutNobel
Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
2012 StandoutNobel
Alzheimer's disease: clinical trials and drug development
2010
Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
2017
Store-Operated Calcium Entry through Orai Is Required for Transcriptional Maturation of the Flight Circuit in Drosophila
2015
Anxiolytic Effects of Phosphodiesterase-2 Inhibitors Associated with Increased cGMP Signaling
2009
Prenatal choline supplementation alters the timing, emotion, and memory performance (TEMP) of adult male and female rats as indexed by differential reinforcement of low-rate schedule behavior
2008
Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development
2005
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
Reduced Synaptic STIM2 Expression and Impaired Store-Operated Calcium Entry Cause Destabilization of Mature Spines in Mutant Presenilin Mice
2014
γ-Secretase and its modulators: Twenty years and beyond
2019
Multiple Pharmacophores for the Selective Activation of Nicotinic α7-Type Acetylcholine Receptors
2008
Cyclic GMP-Hydrolyzing Phosphodiesterases
2008
Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor
2008
Cyclic Guanosine Monophosphate Compartmentation in Rat Cardiac Myocytes
2006
Amyloid-Associated Neuron Loss and Gliogenesis in the Neocortex of Amyloid Precursor Protein Transgenic Mice
2002
Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease
2019
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Compartmentation of Cyclic Nucleotide Signaling in the Heart
2006
ROS and Brain Diseases: The Good, the Bad, and the Ugly
2013
The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease
2018 Standout
Discovery and Development of α7 Nicotinic Acetylcholine Receptor Modulators
2011
Microglial M1/M2 polarization and metabolic states
2015 Standout
Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling
2007 Standout
The Concise Guide toPHARMACOLOGY 2013/14: Enzymes
2013
Works of Gerhard Koenig being referenced
Randomized, Double-Blind, Placebo-Controlled Study of Encenicline, an α7 Nicotinic Acetylcholine Receptor Agonist, as a Treatment for Cognitive Impairment in Schizophrenia
2015
Neuronal Store-Operated Calcium Entry Pathway as a Novel Therapeutic Target for Huntington's Disease Treatment
2011
The Novel α7 Nicotinic Acetylcholine Receptor Agonist N-[(3 R)-1-Azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide Improves Working and Recognition Memory in Rodents
2007
Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease
2016
BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines
2018
Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance
2004
P3‐295: Pharmacokinetic and pharmacodynamic analysis of the gamma‐secretase modulator (GSM) EVP‐0015962
2010
The effect of presenilin on β-amyloid in knock-in mice carrying the human amyloid precursor protein with Swedish and/or London mutation
2000
P4‐348: Evp‐6124: Safety, Tolerability And Cognitive Effects Of A Novel A7 Nicotinic Receptor Agonist In Alzheimer's Disease Patients On Stable Donepezil Or Rivastigmine Therapy
2009
P4‐022: The Gamma Secretase Modulator EVP‐0015962 Improves Cognitive Deficits in Tg2576 Mice Concomitant With Decreases In Aβ42
2010
β-amyloid plaques in amyloid precursor protein knock-in mice
2000