Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
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Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
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Genetics of mouse growth
1998
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Human conditions of insulin-like growth factor-I (IGF-I) deficiency
2012
The DNA-damage response in human biology and disease
2009 StandoutNature
The orderliness of the growth hormone (GH) release process and the mean mass of GH secreted per burst are highly conserved in individual men on successive days.
1996
Growth hormone, 1988.
1988
Unequal impact of age, percentage body fat, and serum testosterone concentrations on the somatotrophic, IGF-I, and IGF-binding protein responses to a three-day intravenous growth hormone-releasing hormone pulsatile infusion in men
1998
Effects of hormone replacement therapy on growth hormone secretion patterns in correlation to somatometric parameters in healthy postmenopausal women
1995
DNA damage and ageing: new-age ideas for an age-old problem
2008
Growth Hormone Treatment of Non–Growth Hormone-Deficient Growth Disorders
2007
Metabolic Clearance Rates of Synthetic Human Growth Hormone in Children, Adult Women, and Adult Men*
1989
Intermittent Plasma Growth Hormone Triggers Tyrosine Phosphorylation and Nuclear Translocation of a Liver-Expressed, Stat 5-related DNA Binding Protein.
1995
Growth Hormone, Exercise, and Aging: The Future of Therapy for the Frail Elderly
1994
MYC on the Path to Cancer
2012 Standout
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
1995 Standout
Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity
2012
mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
2002 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
The genetics of ageing
2010 StandoutNature
Age and Relative Adiposity Are Specific Negative Determinants of the Frequency and Amplitude of Growth Hormone (GH) Secretory Bursts and the Half-Life of Endogenous GH in Healthy Men*
1991
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
1987 Standout
Roles of Growth Hormone and Insulin-like Growth Factor 1 in Mouse Postnatal Growth
2001
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Nature of Altered Growth Hormone Secretion in Hyperthyroidism*
1991
Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry
2015 StandoutNobel
Stat3 as an Oncogene
1999 Standout
Adaptive Stress Response in Segmental Progeria Resembles Long-Lived Dwarfism and Calorie Restriction in Mice
2006
Understanding aging: revealing order out of chaos
2004
Body mass and encephalization in Pleistocene Homo
1997 StandoutNature
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
2002 StandoutNature
The Impact of Gonadal Steroid Hormone Action on Growth Hormone Secretion During Childhood and Adolescence*
1992
Altered endogenous growth hormone secretory kinetics and diurnal GH‐binding protein profiles in adults with chronic liver disease
1995
The growth hormone receptor gene‐disrupted mouse fails to respond to an intermittent fasting diet
2009
Tumor necrosis factor-α converting enzyme
2002
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
1997 StandoutNature
Assessment of Growth Parameters and Life Span of GHR/BP Gene-Disrupted Mice1
2000
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Potential applications of GH secretagogs in the evaluation and treatment of the age-related decline in growth hormone secretion
1997
Metabolic clearance of recombinant human growth hormone in health and chronic renal failure.
1994
Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy
2012 Standout
Growth hormone and metabolism
1988
Mitochondria, Oxidants, and Aging
2005 Standout
Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism
2008
DNA Damage, Aging, and Cancer
2009 Standout
ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling
2008
The GH/IGF-1 axis in ageing and longevity
2013
A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans.
1993
Age to survive: DNA damage and aging
2008
Human Growth Hormone and Human Aging
1993
Ghrelin induces adiposity in rodents
2000 StandoutNature
Polycystic Ovary Syndrome
1995 Standout
A ligand-receptor fusion of growth hormone forms a dimer and is a potent long-acting agonist
2007
Understanding the Odd Science of Aging
2005 Standout
Intravenous Glucose Tolerance Test-Derived Insulin Sensitivity Changes during the Menstrual Cycle*
1991
The Effects of Treatment with Recombinant Human Growth Hormone on Body Composition and Metabolism in Adults with Growth Hormone Deficiency
1989 Standout
Contrasting Effects of Oral and Transdermal Routes of Estrogen Replacement Therapy on 24-Hour Growth Hormone (GH) Secretion, Insulin-Like Growth Factor I, and GH-Binding Protein in Postmenopausal Women*
1991
Thyroid hormones and growth hormone secretion
1992
Mechanisms of aging: public or private?
2002
Effects of Gonadal Steroids on Clearance of Growth Hormone at Steady State in the Rat*
1991
Suppression of growth hormone (GH) secretion by a selective GH-releasing hormone (GHRH) antagonist. Direct evidence for involvement of endogenous GHRH in the generation of GH pulses.
1993
Insulin/IGF signalling and ageing: seeing the bigger picture
2001
[26] Deconvolution analysis of hormone data
1992
Growth Hormone (GH) Insensitivity Due to Primary GH Receptor Deficiency
1994
Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice
2009
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Endocytosis and Degradation of the Growth Hormone Receptor Are Proteasome-dependent
2000
The role of senescent cells in ageing
2014 StandoutNature
A 6-day intracerebroventricular infusion of the growth hormone-releasing peptide KP-102 stimulates food intake in both non-stressed and intermittently-stressed rats
2000
Caloric restriction mimetics: towards a molecular definition
2014
Hormonal regulation of the female enriched GH receptor/binding protein mRNA in rat liver
1995
The Hallmarks of Aging
2013 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Effects of different oral oestrogen formulations on insulin‐like growth factor‐I, growth hormone and growth hormone binding protein in post‐menopausal women
1993
Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses
1998
Multifactorial control of the elimination kinetics of unbound (free) growth hormone (GH) in the human: regulation by age, adiposity, renal function, and steady state concentrations of GH in plasma.
1996
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
2008
Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay.
1995
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Liver-Specific Overexpression of the Insulin-like Growth Factor-I Enhances Somatic Growth and Partially Prevents the Effects of Growth Hormone Deficiency
2006
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
2003 StandoutNature
Dual Defects in Pulsatile Growth Hormone Secretion and Clearance Subserve the Hyposomatotropism of Obesity in Man*
1991
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells
1999
Neuroendocrine Alterations in the Somatotropic Axis in Chronic Renal Failure
1991
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Presenilin diversifies its portfolio
2007
Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation
2004
Hormonal regulation of longevity in mammals
2007
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis
1978 Standout
Do androgens regulate growth hormone-binding protein in adult man?
1995
Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human*
1998 Standout
Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.
1991 StandoutNobel
Dwarfism and Increased Adiposity in the gh1 Mutant Zebrafish vizzini
2013
Low basal and persistent pulsatile growth hormone secretion are revealed in normal and hyposomatotropic men studied with a new ultrasensitive chemiluminescence assay.
1994
The Staphylococcal Enterotoxins and Their Relatives
1990 StandoutScience
Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men
1992
Morphological adaptation to climate in modern and fossil hominids
1994 Standout
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain.
1990
Growth hormone binding protein in the rat: effects of gonadal steroids.
1993
PERK eIF2α Kinase Regulates Neonatal Growth by Controlling the Expression of Circulating Insulin-Like Growth Factor-I Derived from the Liver
2003
Mapping epitopes and antigenicity by site-directed masking
2006 StandoutNobel
Liver and Kidney Growth Hormone (GH) Receptors Are Regulated Differently in Diabetic GH and GH Antagonist Transgenic Mice*
1997
Endogenous growth hormone secretion and clearance rates in normal boys, as determined by deconvolution analysis: relationship to age, pubertal status, and body mass.
1992
Congenital Growth Hormone (GH) Deficiency and Atherosclerosis: Effects of GH Replacement in GH-Naive Adults
2007
Growth hormone-binding protein in normal mice and in transgenic mice expressing bovine growth hormone gene
1995
DOES GROWTH HORMONE RELEASING FACTOR DESENSITIZE THE SOMATOTROPH? INTERPRETATION OF RESPONSES OF GROWTH HORMONE DURING AND AFTER 10‐HOUR INFUSION OF GRF 1–29 AMIDE IN MAN
1986
The growth hormone-binding protein in rat serum is an alternatively spliced form of the rat growth hormone receptor.
1989
Minireview: Role of the Growth Hormone/Insulin-Like Growth Factor System in Mammalian Aging
2005
Association of human corticotropin-releasing hormone to its binding protein in blood may trigger clearance of the complex.
1994
Drug Discovery: A Historical Perspective
2000 StandoutScience
A Hot Spot of Binding Energy in a Hormone-Receptor Interface
1995 StandoutScience
Spermidine in health and disease
2018 StandoutScience
Receptor and Antibody Epitopes in Human Growth Hormone Identified by Homolog-Scanning Mutagenesis
1989 Science
Diurnal variation in the elimination rate of human growth hormone (GH): the half-life of serum GH is prolonged in the evening, and affected by the source of the hormone, as well as by body size and serum estradiol.
1993
Resolving power of isotachophoresis and isoelectric focusing for immunoglobulins
1976 Nobel
Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex
1992 StandoutScience
Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement
2013 Standout
Growth hormone secretory rates in children as estimated by deconvolution analysis of 24-h plasma concentration profiles
1989
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
A quantitative estimation of growth hormone secretion in normal man: reproducibility and relation to sleep and time of day.
1992
A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. III. The neuroendocrine growth hormone axis during late prepuberty.
1996
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Growth hormone secretion in recently operated acromegalic patients.
1994
Steroid Hormone Actions in Tissue Culture Cells and Cell Hybrids—Their Relation to Human Malignancies
1977
A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor.
1991
Placental hormones and the control of maternal metabolism and fetal growth
2011
Notch1 Contributes to Mouse T-Cell Leukemia by Directly Inducing the Expression of c-myc
2006
The Molecular Basis for Growth Hormone–Receptor Interactions
1993
Identification of macromolecules by quantitative polyacrylamide gel electrophoresis and isoelectric focusing: A comparison of three approaches
1977
Induction of Human Interleukin-l by Toxic-Shock-Syndrome Toxin-1
1985
Polyacrylamide gel electrophoresis in sodium dodecyl sulfate-containing buffers using multiphasic buffer systems: Properties of the stack, valid R measurement, and optimized procedure
1977
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation
2006
Rabbit liver growth hormone receptor and serum binding protein. Purification, characterization, and sequence.
1988
Systemic and Local Regulation of the Growth Plate
2003
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
The individual responsiveness to growth hormone (GH) treatment in GH-deficient adults is dependent on the level of GH-binding protein, body mass index, age, and gender.
1996
Distrubance of growth hormone-insulin-like growth factor axis in uraemia
1990
Adenylate cyclase in polyacrylamide gel electrophoresis: Solubilized but active
1978 StandoutNobel
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
1980 StandoutNature
Divergent effects of short term glucocorticoid excess on the gonadotropic and somatotropic axes in normal men.
1992
Murine Models of Life Span Extension
2004
Deletion, But Not Antagonism, of the Mouse Growth Hormone Receptor Results in Severely Decreased Body Weights, Insulin, and Insulin-Like Growth Factor I Levels and Increased Life Span
2003
Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus.
1993
Works of Gerhard Baumann being referenced
Regulation of plasma growth hormone-binding proteins in health and disease
1989
Plasma Transport of Human Growth HormoneIn Vivo*
1990
ABSENCE OF THE PLASMA GROWTH HORMONE-BINDING PROTEIN IN LARON-TYPE DWARFISM*
1987
Low Levels of High-Affinity Growth Hormone-Binding Protein in African Pygmies
1989
Growth hormone isoforms
2009
Growth Hormone-Binding Protein: II. Studies in Pygmies and Normal Statured Subjects*
1990
Effects of single nightly injections of growth hormone—releasing hormone (GHRH 1–29) in healthy elderly men
1997
Plasma Transport of the 20,000-Dalton Variant of Human Growth Hormone (20K): Evidence for a 20K-Specific Binding Site*
1990
Growth Hormone Receptor Is a Target for Presenilin-dependent γ-Secretase Cleavage
2005
Growth Hormone-Binding Protein Activity Is Inversely Related to 24-Hour Growth Hormone Release in Normal Boys*
1991
A rapid and simple assay for growth hormone-binding protein activity in human plasma
1988
Growth hormone binding protein and free growth hormone in chronic renal failure
1996
Plasma Growth Hormone (GH)-Binding Proteins: Effect on GH Binding to Receptors and GH Action*
1991
Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency: Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Placebo-Controlled Trial
2004
Metalloprotease-mediated GH Receptor Proteolysis and GHBP Shedding
2002
Growth Hormone (GH)-induced Dimerization Inhibits Phorbol Ester-stimulated GH Receptor Proteolysis
2001
Basal Plasma Growth Hormone Levels in Man: New Evidence for Rhythmicity of Growth Hormone Secretion*
1990
Short Stature and Decreased Serum Growth Hormone-Binding Protein in the Mountain Ok People of Papua New Guinea*
1991
A Child with Phenotypic Laron Dwarfism and Normal Somatomedin Levels
1989
In vivo kinetics of a covalent growth hormone-binding protein complex
1989
Diurnal Pattern of Plasma Growth Hormone-Binding Protein in Man*
1990
Selective Lack of Growth Hormone (GH) Response to the GH-Releasing Peptide Hexarelin in Patients with GH-Releasing Hormone Receptor Deficiency1
1999
Growth Hormone Heterogeneity: Genes, Isohormones, Variants, and Binding Proteins
1991
Molecular Forms of Circulating Growth Hormone during Spontaneous Secretory Episodes and in the Basal State*
1985
A simple electronic device for the measurement of band migration distances in polyacrylamide gels
1975
A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
1997
The Effect of Lithium on the Osmoregulation of Arginine Vasopressin Secretion*
1983
Free Cortisol Index: A Rapid and Simple Estimation of Free Cortisol in Human Plasma1
1975
The Molecular Nature of Circulating Growth Hormone in Normal and Acromegalic Man: Evidence for a Principal and Minor Monomeric Forms*
1983
Insulin Receptors and Insulin Resistance in Human Pregnancy: Evidence for a Postreceptor Defect in Insulin Action*
1982
The Effect of Circulating Growth Hormone-Binding Protein on Metabolic Clearance, Distribution, and Degradation of Human Growth Hormone*
1987
The Metabolic Clearance, Distribution, and Degradation of Dimeric and Monomeric Growth Hormone (GH): Implications for the Pattern of Circulating GH Forms*
1986
Quantitative removal of carrier ampholytes from protein fractions derived from isoelectric focusing
1975
Tumor Necrosis Factor-α Converting Enzyme (TACE) Is a Growth Hormone Binding Protein (GHBP) Sheddase: The Metalloprotease TACE/ADAM-17 Is Critical for (PMA-Induced) GH Receptor Proteolysis and GHBP Generation*
2000
Phenotype and Genetic Analysis of a Syndrome Caused by an Inactivating Mutation in the Growth Hormone-Releasing Hormone Receptor: Dwarfism of Sindh1
1998
Growth Hormone Doping in Sports: A Critical Review of Use and Detection Strategies
2012
A Specific Growth Hormone-Binding Protein in Human Plasma: Initial Characterization*
1986
Circadian Variation of Basal Plasma Growth Hormone in Man*
1983
Low Plasma Growth Hormone Binding Protein in IDDM
1992
Slow Metabolic Clearance Rate of the 20,000-Dalton Variant of Human Growth Hormone: Implications for Biological Activity*
1985
Circulating Growth Hormone Forms after Stimulation of Pituitary Secretion with Growth Hormone-Releasing Factor in Man*
1984
A highly crosslinked, transparent polyacrylamide gel with improved mechanical stability for use in isoelectric focusing and isotachophoresis
1976