Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer
2008
Aberrant Silencing of Cancer-Related Genes by CpG Hypermethylation Occurs Independently of Their Spatial Organization in the Nucleus
2010
Genomic Profiling of MicroRNA and Messenger RNA Reveals Deregulated MicroRNA Expression in Prostate Cancer
2008
Genetic Unmasking of an Epigenetically Silenced microRNA in Human Cancer Cells
2007
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
2011 StandoutScience
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
The Putative Tumor Suppressor microRNA-101 Modulates the Cancer Epigenome by Repressing the Polycomb Group Protein EZH2
2009
The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function
2007
UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells
2007 Science
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
2010 StandoutScience
CpG island methylator phenotype in cancer
2004
Regulation of LSD1 Histone Demethylase Activity by Its Associated Factors
2005
MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1
2010
Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1
2004 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
2010 Standout
Increased methylation variation in epigenetic domains across cancer types
2011
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
Enhanced Histone Acetylation and Transcription: A Dynamic Perspective
2006
Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?
2006
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin Modifications and Their Function
2007 Standout
Comparing the DNA Hypermethylome with Gene Mutations in Human Colorectal Cancer
2007
Targeting microRNAs in cancer: rationale, strategies and challenges
2010
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
2007 StandoutNobel
Chemical Primer Extension: Efficiently Determining Single Nucleotides in DNA
2005
Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain
2010
Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation
2010
Developmental programming of CpG island methylation profiles in the human genome
2009
Epigenetic therapy of cancer: past, present and future
2006
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
2011
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
Principles and challenges of genome-wide DNA methylation analysis
2010
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Histone Modifications Associated with Somatic Hypermutation
2005
The X-Linked Mental Retardation Gene SMCX/JARID1C Defines a Family of Histone H3 Lysine 4 Demethylases
2007
Active DNA demethylation: many roads lead to Rome
2010
Epigenetic gene silencing in cancer: the DNA hypermethylome
2007
Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance
2011
The Epigenomics of Cancer
2007 Standout
Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse
2005
CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer
2010
MiR-433 and miR-127 Arise from Independent Overlapping Primary Transcripts Encoded by the miR-433-127 Locus
2008
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Epigenetics in Cancer
2008 Standout
The complex language of chromatin regulation during transcription
2007 StandoutNature
Mechanisms regulating imprinted genes in clusters
2007
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Epigenetics in cancer
2009 Standout
A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells
2010
Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey
2006
Role of Protein Methylation in Regulation of Transcription
2005
Epimutations and cancer predisposition: importance and mechanisms
2010
A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells
2007 Standout
H2A.Z Maintenance during Mitosis Reveals Nucleosome Shifting on Mitotically Silenced Genes
2010
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
MicroRNA Expression Patterns to Differentiate Pancreatic Adenocarcinoma From Normal Pancreas and Chronic Pancreatitis
2007
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
Liver‐specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks
2008
Many roads to maturity: microRNA biogenesis pathways and their regulation
2009 Standout
Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis
2011
Epigenetic alteration of microRNAs in DNMT3B-mutated patients of ICF syndrome
2010
Relationship between nucleosome positioning and DNA methylation
2010 Nature
Cancer epigenetics reaches mainstream oncology
2011
Causes and consequences of microRNA dysregulation in cancer
2009 Standout
The epigenetic progenitor origin of human cancer
2005
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
2011
Epigenetics in inflammatory rheumatic diseases
2007
ATF6α Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress
2007
The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing
2010
Non-coding RNAs in human disease
2011 Standout
The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues
2007
Engineering Protein Switches: Sensors, Regulators, and Spare Parts for Biology and Biotechnology
2011
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
2010 Nature
Azacitidine
2005
Polycomb-Repressed Genes Have Permissive Enhancers that Initiate Reprogramming
2011
Polycomb complexes repress developmental regulators in murine embryonic stem cells
2006 StandoutNature
Epigenetics and phenotypic variation in mammals
2006
Epigenetic modifications as therapeutic targets
2010
The Polycomb group protein EZH2 directly controls DNA methylation
2005 StandoutNature
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
MicroRNA signatures in human cancers
2006 Standout
Myc influences global chromatin structure
2006
Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype
2013
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
2007
Proteins that bind methylated DNA and human cancer: reading the wrong words
2008
The DNA methylome
2010
Rethinking how DNA methylation patterns are maintained
2009
Breaking barriers to transcription elongation
2006
Epigenetic modifications and human disease
2010 Standout
Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
2010
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
MicroRNAs — the micro steering wheel of tumour metastases
2009
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Cancer epigenomics: DNA methylomes and histone-modification maps
2007 Standout
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Genome-scale analysis of aberrant DNA methylation in colorectal cancer
2011
Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome
2010
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
2007
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter
2011
The molecular neurobiology of depression
2008 StandoutNature
Template-directed synthesis of a genetic polymer in a model protocell
2008 StandoutNatureNobel
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
2011 Nature
Linking DNA methylation and histone modification: patterns and paradigms
2009 Standout
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Relationship between Gene Body DNA Methylation and Intragenic H3K9me3 and H3K36me3 Chromatin Marks
2011
Chromatin structure and the inheritance of epigenetic information
2010
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
2010
MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia
2011
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine
2005
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes
2011
Histone modification patterns associated with the human X chromosome
2006
N2′→P3′ Phosphoramidate Glycerol Nucleic Acid as a Potential Alternative Genetic System
2009 StandoutNobel
Dominantly Inherited Constitutional Epigenetic Silencing of MLH1 in a Cancer-Affected Family Is Linked to a Single Nucleotide Variant within the 5′UTR
2011
Recruitment of Polycomb group complexes and their role in the dynamic regulation of cell fate choice
2009
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Keeping up NF-κB appearances: Epigenetic control of immunity or inflammation-triggered epigenetics
2006
Epigenetic Reactivation of Tumor Suppressor Genes by a Novel Small-Molecule Inhibitor of Human DNA Methyltransferases
2005
DNA Methylation Dictates Histone H3K4 Methylation
2007
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
A microRNA DNA methylation signature for human cancer metastasis
2008
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Silenced Tumor Suppressor Genes Reactivated by DNA Demethylation Do Not Return to a Fully Euchromatic Chromatin State
2006
Cancer Genome Landscapes
2013 StandoutScience
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
2011
The lymphatic vasculature revisited
2014
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers
2009 StandoutNobel
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
2007
Functions of Site-Specific Histone Acetylation and Deacetylation
2007
Mechanisms of Polycomb gene silencing: knowns and unknowns
2009
Works of Gerda Egger being referenced
Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival
2006
Inhibition of Histone Deacetylation Does Not Block Resilencing of p16 after 5-Aza-2′-Deoxycytidine Treatment
2007
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Constitutive Nucleosome Depletion and Ordered Factor Assembly at the GRP78 Promoter Revealed by Single Molecule Footprinting
2006
Role of Nucleosomal Occupancy in the Epigenetic Silencing of the MLH1 CpG Island
2007
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
2006
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells
2008
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
2008
Delivery of 5-Aza-2′-Deoxycytidine to Cells Using Oligodeoxynucleotides
2007
Enhanced Lymph Vessel Density, Remodeling, and Inflammation Are Reflected by Gene Expression Signatures in Dermal Lymphatic Endothelial Cells in Type 2 Diabetes
2013
Negative and Positive Regulation of Gene Expression by Mouse Histone Deacetylase 1
2006
Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome
2004
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+and ALK−anaplastic large-cell lymphoma
2010
Selective Anchoring of DNA Methyltransferases 3A and 3B to Nucleosomes Containing Methylated DNA
2009
Cancer Epigenetics: Modifications, Screening, and Therapy
2007