Standout Papers
Citation Impact
Citing Papers
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
Impaired cytoadherence of Plasmodium falciparum -infected erythrocytes containing sickle hemoglobin
2008
Myofibroblasts and mechano-regulation of connective tissue remodelling
2002 Standout
TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation
1998
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Alveolar epithelial type II cell: defender of the alveolus revisited
2001
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung
2002
Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent
2001 Standout
Pro‐ versus Anti‐inflammatory Cytokine Profile in Patients with Severe Sepsis: A Marker for Prognosis and Future Therapeutic Options
2000
Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome
1996
Sepsis, Signals, and Surgical Sequelae (A Hypothesis)
1990
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection
1995 Nature
Immunopathological mechanisms in dengue and dengue hemorrhagic fever
2006
Inflammation and cancer
2002 StandoutNature
INTERSEPT
1996
Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis
2001 Standout
Innate immune sensing and its roots: the story of endotoxin
2003 StandoutNobel
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
Early Immune Activation in Acute Dengue Illness Is Related to Development of Plasma Leakage and Disease Severity
1999
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Lactic acidosis and hypoglycaemia in children with severe malaria: pathophysiological and prognostic significance
1994
Exposure of tumor necrosis factor‐α to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin
1995
Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria
1994 Nature
Acute-phase gene expression correlates with intrahepatic tumor necrosis factor-alpha abundance but not with plasma tumor necrosis factor concentrations during sepsis/systemic inflammatory response syndrome in the rat
1996
Tumour necrosis factor α restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice
1992 Nature
Use of Procalcitonin to Shorten Antibiotic Treatment Duration in Septic Patients
2007
Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice
1995 Standout
Persistent Elevation of Inflammatory Cytokines Predicts a Poor Outcome in ARDS
1995
Neutralizing Granulocyte/Macrophage Colony–Stimulating Factor Inhibits Cigarette Smoke–induced Lung Inflammation
2010
The history, properties, and biological effects of cachectin
1988 StandoutNobel
The regional production of cytokines and lactate in sepsis-related multiple organ failure.
1997
Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial
2004
Pioglitazone, a Peroxisome Proliferator-Activated Receptor Gamma Ligand, Suppresses Bleomycin-Induced Acute Lung Injury and Fibrosis
2008
Cytokine Inhibitors and Graft‐versus‐Host Disease
1995
CD4+ T-cell subsets in autoimmunity
1997
Regulatory T Cells
2000 StandoutNobel
Lung Injury in Vivax Malaria: Pathophysiological Evidence for Pulmonary Vascular Sequestration and Posttreatment Alveolar‐Capillary Inflammation
2007
Pathogenesis of Shiga Toxin-Associated Hemolytic Uremic Syndrome
2001
Acute graft-vs-host disease
2001
Lethal Malaria: Marchiafava and Bignami Were Right
2013
Effect of Procalcitonin-Based Guidelines vs Standard Guidelines on Antibiotic Use in Lower Respiratory Tract Infections
2009
Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure
1990 Standout
Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
1993 Nature
Cytolytic pathways in haematopoietic stem-cell transplantation
2002
Keratinocyte-derived tumor necrosis factor and the physiopathology of the skin
1992
Influence of Alternatively and Classically Activated Macrophages on Fibrogenic Activities of Human Fibroblasts
2000
Effect of Mechanical Ventilation on Inflammatory Mediators in Patients With Acute Respiratory Distress Syndrome
1999 Standout
Immune Recognition of Plasmodium-Infected Erythrocytes
2009
IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis
2009
Treatment of Idiopathic Pulmonary Fibrosis with Etanercept
2008
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
2005 Standout
An Evolutionary and Functional Approach to the TNF Receptor/Ligand Family
1994 StandoutNobel
Brain Swelling and Mannitol Therapy in Adult Cerebral Malaria: A Randomized Trial
2011
INCREASED EXPRESSION OF TISSUE CYTOKINES IN GRAFT-VERSUS-HOST DISEASE AFTER SMALL BOWEL TRANSPLANTATION IN THE RAT1
1997
Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier
2001
Exosomes/microvesicles as a mechanism of cell-to-cell communication
2010
Tumor Necrosis Factor-α Blockade: A Novel Therapy for Rheumatic Disease
2002
Dynamics of CNS Barriers: Evolution, Differentiation, and Modulation
2005
Neutrophils Express Tumor Necrosis Factor-α During Mouse Skin Wound Healing
1995
Expression of TNF and the Necessity of TNF Receptors in Bleomycin-Induced Lung Injury in Mice
1998
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli.
1991
High sensitivity of transgenic mice expressing soluble TNFR1 fusion protein to mycobacterial infections: Synergistic action of TNF and IFN‐γ in the differentiation of protective granulomas
1997
Efficacy of a Monoclonal Antibody Directed against Tumor Necrosis Factor in Protecting Neutropenic Rats from Lethal Infection with Pseudomonas aeruginosa
1990
Verotoxins induce apoptosis in human renal tubular epithelium derived cells
1998
The enigma of sepsis
2003
Regulating immunity to malaria
2005
Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection
2016
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Dependence of collagen remodelling on α‐smooth muscle actin expression by fibroblasts
1994
Biodistribution and function of extracellular miRNA-155 in mice
2015 StandoutNobel
University of California/Davis Interdepartmental Conference on Gram-Negative Septicemia
1991 StandoutNobel
Proinflammatory and Anti-inflammatory Cytokines as Mediators in the Pathogenesis of Septic Shock
1997
Malaria
2013 Standout
A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines.
1991 StandoutNobel
Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease
1999 StandoutNobel
Inflammatory Mediators, Cytokines, and Adhesion Molecules in Pulmonary Inflammation and Injury
1996
Acute graft-versus-host disease does not require alloantigen expression on host epithelium
2002
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games
2005
Graft-versus-host disease
2009 Standout
Anti-Inflammatory Cytokines
2000
The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia.
1992 StandoutNobel
In Vivo Investigations on Anti-Fibrotic Potential of Proteasome Inhibition in Lung and Skin Fibrosis
2008
Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
2018
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial
2002 Standout
Evidence of Vascular Damage in Dengue Disease: Demonstration of High Levels of Soluble Cell Adhesion Molecules and Circulating Endothelial Cells
2006
Pathophysiology of Graft-Versus-Host Disease
2006
Coma in fatal adult human malaria is not caused by cerebral oedema
2011
Lung Cytokine Production in Bleomycin-Induced Pulmonary Fibrosis
1992
Procalcitonin to guide duration of antibiotic therapy in intensive care patients: a randomized prospective controlled trial
2009
The role of the CXC chemokines platelet factor-4 (CXCL4/PF-4) and its variant (CXCL4L1/PF-4var) in inflammation, angiogenesis and cancer
2010
Different Pattern of Local and Systemic Release of Proinflammatory and Anti-inflammatory Mediators in Severely Injured Patients with Chest Trauma
1996
Falciparum Malaria: Sticking up, Standing out and Out-standing
2000
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice
1995
Analysis of tumor necrosis factor promoter responses to ultraviolet light.
1994 StandoutNobel
Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
1993
Innate sensing of malaria parasites
2014
Atherosclerosis — An Inflammatory Disease
1999 Standout
Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.
1991
Mechanisms of Myofibroblast Activity and Phenotypic Modulation
1999
Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis
2007
Increased ability of peripheral blood lymphocytes to degrade laminin in multiple sclerosis
2004
Coma Associated with Microscopy-Diagnosed Plasmodium vivax: A Prospective Study in Papua, Indonesia
2011
Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome
2011
The Pathophysiology and Treatment of Sepsis
2003 Standout
Innate immunity to malaria
2004
Intestinal graft-versus-host disease is initiated by donor T cells distinct from classic cytotoxic T lymphocytes.
1989
The −308 tumor necrosis factor-α promoter polymorphism effects transcription
1997
Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial
2010 Standout
Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin
1991
Treatment of Septic Shock with the Tumor Necrosis Factor Receptor:Fc Fusion Protein
1996
Reduction of conventional dendritic cells during Plasmodium infection is dependent on activation induced cell death by type I and II interferons
2015
Induction of Proinflammatory Responses in Macrophages by the Glycosylphosphatidylinositols of Plasmodium falciparum
2004
Immunopathogenesis of Dengue Hemorrhagic Fever
1999
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
1993
Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: A systematic review and meta-analysis
2006
Development of anti-TNF therapy for rheumatoid arthritis
2002
Corneal stromal wound healing in refractive surgery: the role of myofibroblasts
1999
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.
1995
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease
1994
Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria
2016
Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised study
2009
Inflammatory Cytokines in the BAL of Patients With ARDS
1995
The Neuropathology of Fatal Cerebral Malaria in Malawian Children
2011
Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor
1994
Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism
2006
Locally applied GM-CSF induces the accumulation of α-smooth muscle act in containing myofibroblasts
1991
CDP571, a humanized antibody to human tumor necrosis factor-alpha
1995
LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation
2001
Protection from septic shock by neutralization of macrophage migration inhibitory factor
2000
Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-β1-dependent mechanism in vitro
2001
The role of lymphotoxin in development and maintenance of secondary lymphoid tissues
2003
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Pentoxifylline treatment of mice with chronic pulmonary tuberculosis accelerates the development of destructive pathology
2001
Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice
1994
Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor
1990
A Trial of Artemether or Quinine in Children with Cerebral Malaria
1996
Relationship of Cell‐Free Hemoglobin to Impaired Endothelial Nitric Oxide Bioavailability and Perfusion in Severe Falciparum Malaria
2009
Tumor necrosis factor in mediating experimental Haemophilus influenzae type B meningitis.
1989 StandoutNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Type I interferons suppress CD4+ T‐cell‐dependent parasite control during blood‐stage Plasmodium infection
2011
Dengue
2007 Standout
Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality
2016
Upregulation of the p75 But Not the p55 TNF- α Receptor mRNA after Silica and Bleomycin Exposure and Protection from Lung Injury in Double Receptor Knockout Mice
1999
Procalcitonin Kinetics as a Prognostic Marker of Ventilator-associated Pneumonia
2004
Procalcitonin Guidance of Antibiotic Therapy in Community-acquired Pneumonia
2006
Multiple System Organ Failure
1998
Total Body Irradiation and Acute Graft-Versus-Host Disease: The Role of Gastrointestinal Damage and Inflammatory Cytokines
1997
A Tumor Necrosis Factor Mimetic Peptide Activates a Murine Macrophage Cell Line To Inhibit Mycobacterial Growth in a Nitric Oxide-Dependent Fashion
1998
Toll-Like Receptor 7 Mediates Early Innate Immune Responses to Malaria
2013
Activation of endothelial cells via antibody-enhanced dengue virus infection of peripheral blood monocytes
1997
The pathogenesis of Plasmodium falciparum malaria in humans: insights from splenic physiology
2010
Sequestration From Immune CD4 + T Cells of Mycobacteria Growing in Human Macrophages
1993 StandoutScienceNobel
Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria
2008
Pathophysiologic and Prognostic Role of Cytokines in Dengue Hemorrhagic Fever
1998
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Modulation of acute graft-versus-host-disease after allogeneic bone marrow transplantation by tumor necrosis factor alpha (TNF alpha) release in the course of pretransplant conditioning: role of conditioning regimens and prophylactic application of a monoclonal antibody neutralizing human TNF alpha (MAK 195F)
1995
Constitutive synthesis of tumor necrosis factor in the thymus.
1992 StandoutNobel
An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin
1996
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
2007
Selected Treatment Strategies for Septic Shock Based on Proposed Mechanisms of Pathogenesis
1994
Association of TNF2, a TNF-α Promoter Polymorphism, With Septic Shock Susceptibility and Mortality
1999 Standout
MALARIA PARASITE DEVELOPMENT IN MOSQUITOES
1998
Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses
2010
MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice
2018
Blood-brain barrier disruption in multiple sclerosis
2003
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
1993 Standout
Anti-TNFα Therapy of Rheumatoid Arthritis: What Have We Learned?
2001
Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.
1989
AN ULTRASTRUCTURAL STUDY OF THE BRAIN IN FATAL PLASMODIUM FALCIPARUM MALARIA
2003
Soluble receptors in human disease
1998
Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-κB and AP-1
2002
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
2003 Standout
Transmembrane TNF Induces an Efficient Cell-Mediated Immunity and Resistance toMycobacterium bovisBacillus Calmette-Guerin Infection in the Absence of Secreted TNF and Lymphotoxin-α
2002
Characterization of tumor necrosis factor-deficient mice
1997
TNF-TNFR2 Interactions Are Critical for the Development of Intestinal Graft-Versus-Host Disease in MHC Class II-Disparate (C57BL/6J→C57BL/6J × bm12)F1 Mice
2002
Interferon-Beta Prevents Cytokine-Induced Neutrophil Infiltration and Attenuates Blood–Brain Barrier Disruption
2003
Recombinant Human IFN-α Inhibits Cerebral Malaria and Reduces Parasite Burden in Mice
2007
Recipient Tumor Necrosis Factor- and Interleukin-10 Gene Polymorphisms Associate With Early Mortality and Acute Graft-Versus-Host Disease Severity in HLA-Matched Sibling Bone Marrow Transplants
1999
Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome.
1996
TLR9 and MyD88 Are Crucial for the Development of Protective Immunity to Malaria
2012
Proinflammatory and regulatory cytokines and chemokines in infants with uncomplicated and severePlasmodium falciparummalaria
2011
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Downregulation of proinflammatory cytokine release in whole blood from septic patients
1995
Tuberculosis: Commentary on a Reemergent Killer
1992 StandoutScience
Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease
2007
Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood‐stage P lasmodium bergheiANKA
2013
Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid
1997
Effect of Shiga toxin and Shiga-like toxins on eukaryotic cells
2001
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.
1991
Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality
2014
Transforming Growth Factor-β Mediates Astrocyte-Specific Regulation of Brain Endothelial Anticoagulant Factors
1999
The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation
2000
Biology and biogenesis of shed microvesicles
2016
Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor.
1996
Thalidomide treatment reduces tumor necrosis factor alpha production and enhances weight gain in patients with pulmonary tuberculosis.
1995
Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation
1997 Standout
Cytokine dysregulation and acute graft-versus-host disease
1992
Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin.
1991
Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.
1996
Digestive vacuoles of Plasmodium falciparum are selectively phagocytosed by and impair killing function of polymorphonuclear leukocytes
2011
Alveolar macrophage apoptosis and TNF-α, but not p53, expression correlate with murine response to bleomycin
1998
Transforming Growth Factor (TGF)-β1–producing Regulatory T Cells Induce Smad-mediated Interleukin 10 Secretion That Facilitates Coordinated Immunoregulatory Activity and Amelioration of TGF-β1–mediated Fibrosis
2003
ADAMTS13 Deficiency with Elevated Levels of Ultra-Large and Active von Willebrand Factor in P. falciparum and P. vivax Malaria
2009
Chemodynamic Therapy: Tumour Microenvironment‐Mediated Fenton and Fenton‐like Reactions
2018 Standout
Genetic Polymorphisms in the Tumor Necrosis Factor Locus Influence Non-Hodgkin's Lymphoma Outcome
1998
Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light.
1990
Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease
1992
Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine
1990
Pretreatment with recombinant murine tumor necrosis factor alpha/cachectin and murine interleukin 1 alpha protects mice from lethal bacterial infection.
1989
Platelet-mediated clumping of Plasmodium falciparum -infected erythrocytes is a common adhesive phenotype and is associated with severe malaria
2001
Thalidomide Treatment Reduces Tumor Necrosis Factor α Production and Enhances Weight Gain in Patients with Pulmonary Tuberculosis
1995
Assessment of ability of murine and human anti-lipid A monoclonal antibodies to bind and neutralize lipopolysaccharide.
1993
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Identification of cysteine-rich domains of the type 1 tumor necrosis factor receptor involved in ligand binding.
1992
Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis
1997
PanR1, a Dominant Negative Missense Allele of the Gene Encoding TNF-α (Tnf), Does Not Impair Lymphoid Development
2006 StandoutNobel
Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process.
1994
Genetic Polymorphisms in the Tumor Necrosis Factor Locus Influence Non-Hodgkin's Lymphoma Outcome
1998
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Integrating mechanisms of pulmonary fibrosis
2011 Standout
Donor CD4-enriched cells of Th2 cytokine phenotype regulate graft- versus-host disease without impairing allogeneic engraftment in sublethally irradiated mice
1994
Works of Georges E. Grau being referenced
Cerebral malaria: Mediators, mechanical obstruction or more?
1994
Imaging Experimental Cerebral MalariaIn Vivo: Significant Role of Ischemic Brain Edema
2005
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane‐bound TNF in experimental cerebral malaria
1997
Pathogenic Role of P-Selectin in Experimental Cerebral Malaria
2004
Magnetic Resonance Spectroscopy Reveals an Impaired Brain Metabolic Profile in Mice Resistant to Cerebral Malaria Infected with Plasmodium berghei ANKA
2007
The CTLA-4 and PD-1/PD-L1 Inhibitory Pathways Independently Regulate Host Resistance to Plasmodium-induced Acute Immune Pathology
2012
Breast Cancer-Derived Microparticles Display Tissue Selectivity in the Transfer of Resistance Proteins to Cells
2013
Tumor Necrosis Factor and Disease Severity in Children with Falciparum Malaria
1989
Cerebral Malaria - A Neurovascular Pathology with Many Riddles Still to be Solved
2004
Tumor Necrosis Factor and Interleuktn-1 in the Serum of Children with Severe Infectious Purpura
1988
Brain microvascular endothelial cells and leukocytes derived from patients with multiple sclerosis exhibit increased adhesion capacity
1997
Murine Cerebral Malaria Development Is Independent of Toll-Like Receptor Signaling
2007 StandoutNobel
Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk
1996
Severe Plasmodium falciparum Malaria Is Associated with Circulating Ultra-Large von Willebrand Multimers and ADAMTS13 Inhibition
2009
Modulation of the transcripts for tumor necrosis factor‐α and its receptors in vivo
1994
The Role of Animal Models for Research on Severe Malaria
2012
Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica
1993
Immunological processes in malaria pathogenesis
2005
Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice
2007
Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria
2003
Plasma Cytokine Levels in Hemolytic Uremic Syndrome
1995
In the Eye of Experimental Cerebral Malaria
2011
Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis
1990 Nature
Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation
2010
The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection
1989
The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes
2012
A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction
2006
Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide‐induced lethality
1991
Interleukin‐10 modulates susceptibility in experimental cerebral malaria
1997
Current perspectives on the mechanism of action of artemisinins
2006
A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI
2008
Role of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Fibrosis Induced in Mice by Bleomycin
1993
High Bronchoalveolar Levels of Tumor Necrosis Factor and Its Inhibitors, Interleukin-1, Interferon, and Elastase, in Patients with Adult Respiratory Distress Syndrome after Trauma, Shock, or Sepsis
1992
Both Functional LTβ Receptor and TNF Receptor 2 Are Required for the Development of Experimental Cerebral Malaria
2008
Transgenic mice expressing high levels of soluble TNF‐R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections
1995
Tumor necrosis factor and immunopathology
1991
Dengue virus infection of human microvascular endothelial cells from different vascular beds promotes both common and specific functional changes
2005
Platelet Accumulation in Brain Microvessels in Fatal Pediatric Cerebral Malaria
2003
Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells
2009
Platelets ReorientPlasmodium falciparum–Infected Erythrocyte Cytoadhesion to Activated Endothelial Cells
2004
Prognostic Values of Tumor Necrosis Factor/Cachectin, Interleukin-l, Interferon- , and Interferon- in the Serum of Patients with Septic Shock
1990
Anti-parasite effects of cytokines in malaria
1990
Diagnostic Value of Procalcitonin, Interleukin-6, and Interleukin-8 in Critically Ill Patients Admitted with Suspected Sepsis
2001
Role of TNF and IL-1 in infections with Toxoplasma gondii.
1990
Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria.
1992
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.
1989
H-2D haplotype-linked expression and involvement of TNF-alpha in Th2 cell-mediated tissue inflammation.
1994
Anti-TNF therapy inhibits fever in cerebral malaria
1993
Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: a prospective double-blind study. J5 study Group.
1992
In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant
1999
Platelets Potentiate Brain Endothelial Alterations Induced byPlasmodium falciparum
2005
Platelets play an important role in TNF-induced microvascular endothelial cell pathology.
1997
T lymphocyte interferon-gamma production induced byPlasmodium falciparumantigen is high in recently infected non-immune and low in immune subjects
1990
Tumor Necrosis Factor (Cachectin) as an Essential Mediator in Murine Cerebral Malaria
1987 Science
Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease.
1987
Imbalance between tumour necrosis factor-alpha and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group.
1992
Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions.
1991
Pneumopathies of the graft-versus-host reaction. Alveolitis associated with an increased level of tumor necrosis factor mRNA and chronic interstitial pneumonitis.
1989
Requirement for Tumor Necrosis Factor Receptor 2 Expression on Vascular Cells To Induce Experimental Cerebral Malaria
2002
Anin vitroblood–brain barrier model: Cocultures between endothelial cells and organotypic brain slice cultures
1998
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor.
1989
Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings
2009
Cerebral Malaria Pathogenesis: Revisiting Parasite and Host Contributions
2012
Phenotypic and functional analysis of pulmonary microvascular endothelial cells from patients with acute respiratory distress syndrome.
1996
Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor alpha and interleukin 6. Comparison of O side chain-specific antibodies with core LPS antibodies.
1990
Tumor necrosis factor alpha is involved in mouse growth and lymphoid tissue development.
1992
Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.
1992
Haemostatic Properties of Human Pulmonary and Cerebral Microvascular Endothelial Cells
1997
An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium
1993
Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis.
1993
Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria.
2011
TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction.
1994
Interferon-beta inhibits activated leukocyte migration through human brain microvascular endothelial cell monolayer.
1999
Tumor necrosis factor in the pathogenesis of infectious diseases
1993 StandoutNobel
Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states.
1991
Heparin induces alpha-smooth muscle actin expression in cultured fibroblasts and in granulation tissue myofibroblasts.
1992
Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells
2013
Tumor necrosis factor in Plasmodium falciparum malaria: high plasma level is associated with fever, but high production capacity is associated with rapid fever clearance.
1997
Immunopathology of thrombocytopenia in experimental malaria.
1988
Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis.
1990
Tumor necrosis factor alpha production as a possible predictor of relapse in patients with multiple sclerosis.
1993