Standout Papers
Citation Impact
Citing Papers
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
Multi-class texture analysis in colorectal cancer histology
2016
Deep Learning Models for Histopathological Classification of Gastric and Colonic Epithelial Tumours
2020
O-Glycosylation of Nuclear and Cytosolic Proteins
2000
Dynamic O-Glycosylation of Nuclear and Cytosolic Proteins
2001
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
1995 Standout
TSH stimulates adipogenesis in mouse embryonic stem cells
2007
Modular Assembly of Glycoproteins: Towards the Synthesis of GlyCAM‐1 by Using Expressed Protein Ligation
2004 StandoutNobel
Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds
2002
Foundation models for generalist medical artificial intelligence
2023 StandoutNature
Novel applications of liposomes
1998
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Effect of Tumor Necrosis Factor-α, Interferon-γ, and Transforming Growth Factor-β on Adipogenesis and Expression of Thyrotropin Receptor in Human Orbital Preadipocyte Fibroblasts1
2001
Catalysis for fluorination and trifluoromethylation
2011 StandoutNature
Functional Expression of O-linked GlcNAc Transferase
2000
Deep neural network models for computational histopathology: A survey
2020
An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis
2019
O-GlcNAc cycling: Implications for neurodegenerative disorders
2009
Decoding ALS: from genes to mechanism
2016 StandoutNature
Mechanically Activated Ion Channels
2015 StandoutNobel
The experimental development of bioreductive drugs and their role in cancer therapy
1993
Graves' Ophthalmopathy
2010 Standout
Multimodal biomedical AI
2022 Standout
Designing deep learning studies in cancer diagnostics
2021
Membrane Fusion
2003 StandoutNobel
Dynamics of Diacylglycerol Kinase ζ Translocation in Living T-cells
2002
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine
2009
Deep learning in histopathology: the path to the clinic
2021 Standout
Adipose thyrotrophin receptor expression is elevated in Graves' and thyroid eye diseases ex vivo and indicates adipogenesis in progress in vivo
2003
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Targeting gene expression to hypoxic tumor cells
1997 StandoutNobel
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
2000 StandoutNobel
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Mucin Granule Intraluminal Organization in Living Mucous/Goblet Cells
2005 StandoutNobel
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Synthetic glycopeptides and glycoproteins as tools for biology
2004 StandoutNobel
O-GlcNAc modification of nucleocytoplasmic proteins and diabetes
2005
Uptake and metabolism of exogenous glycosphingolipids by cultured cells
2001
The inflammatory reflex
2002 StandoutNature
System Xc−and Apolipoprotein E Expressed by Microglia Have Opposite Effects on the Neurotoxicity of Amyloid-β Peptide 1–40
2006
O-GlcNAc Modification Is an Endogenous Inhibitor of the Proteasome
2003
Immunohistochemistry profiles of breast ductal carcinoma: factor analysis of digital image analysis data
2012
Artificial intelligence in digital pathology — new tools for diagnosis and precision oncology
2019
Perioperative Normothermia to Reduce the Incidence of Surgical-Wound Infection and Shorten Hospitalization
1996 Standout
A Multiple-Instance Learning-Based Convolutional Neural Network Model to Detect the IDH1 Mutation in the Histopathology Images of Glioma Tissues
2020
Elephantiasic Pretibial Myxedema: Insight into and a Hypothesis Regarding the Pathogenesis of the Extrathyroidal Manifestations of Graves' Disease
2000
Interaction of fragments B and C of tetanus toxin with neural and thyroid membranes and with gangliosides.
1980
The Biosynthesis of Collagen and Its Disorders
1979
Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.
1982
Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions
2004
Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation
2010
Explainable Machine Learning for Scientific Insights and Discoveries
2020
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
Amino-terminal extensions on skin collagen from sheep with a genetic defect in conversion of procollagen into collagen
1976
The Thyrotropin (TSH)-Releasing Hormone Receptor: Interaction with TSH and Autoantibodies*
1998
Thyrotropin receptors in adipose tissue, retro-orbital tissue and lymphocytes
1978
Bacterial toxins: cellular mechanisms of action
1984
T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes
1982 StandoutNatureNobel
Computational pathology definitions, best practices, and recommendations for regulatory guidance: a white paper from the Digital Pathology Association
2019
Structure, function, and antigenicity of cholera toxin
1979
Conjugated Polymer-Based Chemical Sensors
2000 Standout
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts
1983 StandoutNatureNobel
Molecular Background of Leak K+Currents: Two-Pore Domain Potassium Channels
2010
Cholera Toxin Crystals Suitable for X-ray Diffraction
1977 Science
Enzymes of normal and malignant trophoblast: Phosphoglucose isomerase, phosphoglucomutase, hexokinase, lactate dehydrogenase, and alkaline phosphatase
1975
A chemical approach for identifying O -GlcNAc-modified proteins in cells
2003 StandoutNobel
Structure-function studies of cholera toxin and its A and B protomers. Modification of tryptophan residues.
1981
The Chemistry and Biology of Cholera Toxi
1980
Activation of the beta 2-adrenergic receptor promotes growth and differentiation in thyroid cells.
1989 StandoutNobel
Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels
1982 Standout
Membrane receptors for bacterial toxins
1983
Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.
1987 StandoutNobel
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Tryptophan residues of cholera toxin and its A and B protomers. Intrinsic fluorescence and solute quenching upon interacting with the ganglioside GM1, oligo-GM1, or dansylated oligo-GM1.
1981
A molecular basis for bidirectional communication between the immune and neuroendocrine systems.
1989
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells
1986 StandoutNatureNobel
Cholera Toxin Crystals Suitable for X-ray Diffraction
1977 Science
Two-dimensional crystals of cholera toxin B-subunit-receptor complexes: projected structure at 17-A resolution.
1986 StandoutNobel
Micromanaging insulin secretion
2004 StandoutNobel
Chemical and immunochemical studies on the receptor binding domain of cholera toxin B subunit.
1985
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels.
1987 StandoutNobel
Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase
2003
Covalent structure of the beta chain of cholera enterotoxin.
1977
Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin
1985 StandoutNature
Membrane fusion protein synexin (annexin VII) as a Ca2+/GTP sensor in exocytotic secretion.
1996
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
2002
Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretion
2003
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Glycan‐dependent signaling: O‐linked N‐acetylglucosamine
2001
Three-Dimensional Structure of Cholera Toxin Penetrating a Lipid Membrane
1988 StandoutScienceNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
The Relationship of Growth and Adenylate Cyclase Activity in Cultured Thyroid Cells: Separate Bioeffects of Thyrotropin
1983
Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions
2008
Molecular Origin of Blood‐Based Infrared Spectroscopic Fingerprints**
2021 StandoutNobel
Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes
2008 StandoutNobel
Quantitative phase imaging in biomedicine
2018 Standout
Structure of molecular aggregates of 1-(3-sn-phosphatidyl)-l-myo-inositol 3,4-bis(phosphate) in water
1981
Differentiation of Human Orbital Preadipocyte Fibroblasts Induces Expression of Functional Thyrotropin Receptor1
1999
Biochemical characteristics and biological significance of the genetically-distinct collagens
1976
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Pro—Gln: The procollagen peptidase cleavage site in the α1 (I) chain of dermatosparactic calf skin procollagen
1978 StandoutNobel
Membrane potential changes during mitogenic stimulation of mouse spleen lymphocytes
1980
Selective dephosphorylation of proteins containing phosphotyrosine by alkaline phosphatases.
1981 StandoutNobel
Works of George Lee being referenced
Interferon Interactions with Thyroid Cells
1982
Effects of thyrotropin on the thyroid cell membrane: Hyperpolarization induced by hormone-receptor interaction
1977
Elevated O-LinkedN-Acetylglucosamine Metabolism in Pancreatic β-Cells
1999
Image analysis and machine learning in digital pathology: Challenges and opportunities
2016 Standout
Nuclear Shape and Architecture in Benign Fields Predict Biochemical Recurrence in Prostate Cancer Patients Following Radical Prostatectomy: Preliminary Findings
2016
Immunolocalization of synexin (annexin VII) in adrenal chromaffin granules and chromaffin cells: evidence for a dynamic role in the secretory process
1992
Annexin 5 and apolipoprotein E2 protect against Alzheimer’s amyloid-β-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site
2002
Applications of machine learning in drug discovery and development
2019 Standout
Co-Occurring Gland Angularity in Localized Subgraphs: Predicting Biochemical Recurrence in Intermediate-Risk Prostate Cancer Patients
2014
Computer-aided prognosis: Predicting patient and disease outcome via quantitative fusion of multi-scale, multi-modal data
2011
Highly Sensitive and Stable Phosphatidylserine Liposome Aggregation Assay for Annexins
1997
Evaluating stability of histomorphometric features across scanner and staining variations: prostate cancer diagnosis from whole slide images
2016
Thyrotropin interactions with human fat cell membrane preparations and the finding of a soluble thyrotropin binding component
1976
Thyrotropin Receptors and Gangliosides
1980
Interaction of phosphatidic acid and phosphatidylserine with the Ca2+-ATPase of sarcoplasmic reticulum and the mechanism of inhibition
1998
Structure: Function studies of receptors for thyrotropin and tetanus toxin: Lipid modulation of effector binding to the glycoprotein receptor component
1978
The use of the D-T diaphorase for the detection of foci of early neoplastic transformation in rat liver
1978
Critical micelle concentrations of gangliosides
1979
The binding of thyrotropin to liposomes containing gangliosides
1977
Calf Tendon Procollagen Peptidase: Its Purification and Endopeptidase Mode of Action
1974
Cloning and localization of a double-pore K channel, KCNK1: exclusive expression in distal nephron segments
1997
Feature Importance in Nonlinear Embeddings (FINE): Applications in Digital Pathology
2015
An Expedient Synthesis of 6α-Fluoroursodeoxycholic Acid
2002
Sequence similarity between cholera toxin and glycoprotein hormones: Implications for structure activity relationship and mechanism of action
1976
Placental enzymes: Specific activities and isoenzyme patterns during early and late gestation
1971