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Citing Papers
Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2
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2001 Science
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
1999 StandoutNature
p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
2002 Nature
Focal cerebral ischemia in rats induces expression of p75 neurotrophin receptor in resistant striatal cholinergic neurons
1998
Reduced Size of Retinal Ganglion Cell Axons and Hypomyelination in Mice Lacking Brain-Derived Neurotrophic Factor
1997
Regulation of Oligodendrocyte Development and CNS Myelination by Growth Factors: Prospects for Therapy of Demyelinating Disease
1996
Neurotrophins are required for nerve growth during development
2001
Control of oligodendrocyte number in the developing rat optic nerve
1994
Pericytes are required for blood–brain barrier integrity during embryogenesis
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Transplanting oligodendrocyte progenitors into the adult CNS
1997
Apoptosis in the nervous system
2000 StandoutNature
K‐252 Compounds: Modulators of Neurotrophin Signal Transduction
1992
Novel class of pain drugs based on antagonism of NGF
2005
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
1999 Nature
Proliferation and Cell Cycle Dynamics in the Developing Stellate Ganglion
2013
Target attraction: Are developing axons guided by chemotropism?
1991
A Local Action of Neurotrophin-3 Prevents the Death of Proliferating Sensory Neuron Precursor Cells
1996
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR
1999
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
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1995
Apoptosis occurs in the oligodendroglial lineage, and is prevented by basic fibroblast growth factor
1995
Regeneration in the adult central nervous system: Experimental repair strategies
1997
Axotomy induces nerve growth factor receptor immunoreactivity in spinal motor neurons
1991
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor
1991
Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
1992
Piezo2 is required for Merkel-cell mechanotransduction
2014 StandoutNatureNobel
Postnatal loss of Merkel cells, but not of slowly adapting mechanoreceptors in mice lacking the neurotrophin receptor p75
1999
NMR structure of the death domain of the p75 neurotrophin receptor
1997
Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system
1992
Neurotrophic factors and synaptic plasticity
1995
Defects in enteric innervation and kidney development in mice lacking GDNF
1996 StandoutNature
The many faces of p75NTR
2002
The GDNF family: Signalling, biological functions and therapeutic value
2002
Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family
1990
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Oligodendrocyte maturation and progenitor cell proliferation are independently regulated by thyroid hormone
1997
The Cytoplasmic and Transmembrane Domains of the p75 and Trk A Receptors Regulate High Affinity Binding to Nerve Growth Factor
2001
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
Neurotrophins and their receptors: A convergence point for many signalling pathways
2003 Standout
The trk proto-oncogene encodes a receptor for nerve growth factor
1991
Neurotrophin signal transduction in the nervous system
2000 Standout
BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF
1991
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
2011 StandoutNature
Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects
2005
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
1991
Structural and Mechanistic Insights into Nerve Growth Factor Interactions with the TrkA and p75 Receptors
2007
Binding of nerve growth factor to its p75 receptor in stressed cells induces selective IκB‐β degradation and NF‐κB nuclear translocation
2001
Neurotrophic Mechanisms in Drug Addiction
2004
Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells
1994
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
In situ hybridization detection of trka mRNA in brain: Distribution, colocalization with p75NGFR and up‐regulation by nerve growth factor
1994
Inflammation promotes survival and migration of the CG4 oligodendrocyte progenitors transplanted in the spinal cord of both inflammatory and demyelinated EAE rats
1998
The nerve growth factor family
1990
Cell-Intrinsic Timers and Thyroid Hormone Regulate the Probability of Cell-Cycle Withdrawal and Differentiation of Oligodendrocyte Precursor Cells
1998
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
The role of neurotrophins in the developing nervous system
1994
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
GDNF signalling through the Ret receptor tyrosine kinase
1996 StandoutNature
Sez-6 Proteins Affect Dendritic Arborization Patterns and Excitability of Cortical Pyramidal Neurons
2007
NGF and BDNF are differentially modulated by visual experience in the developing geniculocortical pathway
1995
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
1994
Neuronal Cell Death
1998
Neurotrophins Induce Sphingomyelin Hydrolysis
1995
mRNAS for one, two or three members of trk receptor family are expressed in single rat trigeminal ganglion neurons
1996
Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product
1992
NGF Controls Axonal Receptivity to Myelination by Schwann Cells or Oligodendrocytes
2004
Glial cell lineage and development
1994
Widespread transcription at neuronal activity-regulated enhancers
2010 StandoutNature
A motor neuron‐specific epitope and the low‐affinity nerve growth factor receptor display reciprocal patterns of during development, axotomy, and regeneration
1993
The nerve growth factor family of receptors
1992
Neurotrophins Rapidly Modulate Growth Cone Response to the Axon Guidance Molecule, Collapsin-1
1998
Induction of nerve growth factor receptor (p75NGFr) mRNA within hypoglossal motoneurons following axonal injury
1992
New insights into BDNF function in depression and anxiety
2007
Blockade of Endogenous Ligands of TrkB Inhibits Formation of Ocular Dominance Columns
1997
The molecular neurobiology of depression
2008 StandoutNature
New protein fold revealed by a 2.3-Å resolution crystal structure of nerve growth factor
1991 Nature
The p75 neurotrophin receptor
1994
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
Neurotrophin activates signal transduction in oligodendroglial cells: Expression of functionalTrkC receptor isoforms
1996
Neurotrophin Binding to the p75 Receptor Modulates Rho Activity and Axonal Outgrowth
1999
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents
1994
Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
1992
Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells
1998
Neurotrophin signaling through the p75 neurotrophin receptor
2002
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor
1991 Nature
Dynamic regulation of BDNF and NT-3 expression during visual system development
2000
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Genome-wide detection and characterization of positive selection in human populations
2007 StandoutNature
SELECTIVITY IN NEUROTROPHIN SIGNALING : Theme and Variations
2003
Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice
1996
Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons.
1995
Monocular deprivation effects in the rat visual cortex and lateral geniculate nucleus are prevented by nerve growth factor (NGF). II. Lateral geniculate nucleus
1993
Regulation of Neurotrophin-3 Expression by Epithelial-Mesenchymal Interactions: The Role of Wnt Factors
1999 StandoutScienceNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
p75 and Trk: A two-receptor system
1995
Neuronal life and death decisions: functional antagonism between the Trk and p75 neurotrophin receptors
1999
Neurotrophin-3 Is a Survival FactorIn Vivofor Early Mouse Trigeminal Neurons
1996
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis
1995 StandoutScience
Activation of Rac GTPase by p75 Is Necessary for c-junN-Terminal Kinase-Mediated Apoptosis
2002
High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors.
1994
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers
2004 StandoutScience
Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress
2006 StandoutScience
Regulation of neurotrophin receptors during the maturation of the mammalian visual system
1994
Acute Morphogenic and Chemotropic Effects of Neurotrophins on Cultured EmbryonicXenopusSpinal Neurons
1997
Classical Electrostatics in Biology and Chemistry
1995 StandoutScience
Neural Stem and Progenitor Cells: A Strategy for Gene Therapy and Brain Repair
1998
GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro
1995
Axonal Control of Oligodendrocyte Development
1999
A Novel p75NTR Signaling Pathway Promotes Survival, Not Death, of Immunopurified Neocortical Subplate Neurons
2001
Synaptic Activity and the Construction of Cortical Circuits
1996 StandoutScience
Death Receptors: Signaling and Modulation
1998 StandoutScience
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Neurotrophin-3 and Brain-Derived Neurotrophic Factor Induce Oligodendrocyte Proliferation and Myelination of Regenerating Axons in the Contused Adult Rat Spinal Cord
1998
Mice lacking NT-3, and its receptor TrkC, exhibit profound deficiencies in CNS glial cells
1999
Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice
2013 Standout
Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia.
1992
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
1994 StandoutScience
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Neural Science
2000 StandoutNobel
Neurotrophins and Neuronal Plasticity
1995 StandoutScience
Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex
1992 StandoutScience
Brain-Derived Neurotrophic Factor Acutely Inhibits AMPA-Mediated Currents in Developing Sensory Relay Neurons
2000
Effects of nerve growth factor on neuronal plasticity of the kitten visual cortex.
1993
Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System
2001 Standout
Prenatal and postnatal requirements of NT-3 for sympathetic neuroblast survival and innervation of specific targets
1996
Growth Factors and Cancer
1991 StandoutScience
The Neurotrophin Receptor p75 NTR as a Positive Modulator of Myelination
2002 Science
Physiology of the Neurotrophins
1996 Standout
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
2010 Standout
Nerve growth factor (NGF) prevents the shift in ocular dominance distribution of visual cortical neurons in monocularly deprived rats
1992
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
The Molecular Biology of Axon Guidance
1996 StandoutScience
Remyelination of mouse spinal cord axons demyelinated by local injection of lysolecithin
1995
Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex.
1992
Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.
1993
A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development
1994
NEUROTROPHINS AND SYNAPTIC PLASTICITY
1999
Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System
2008
The Receptor for Ciliary Neurotrophic Factor
1991 Science
Functional Interactions of Neurotrophins and Neurotrophin Receptors
1995
Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice
1999
Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor
1994 Science
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons.
1993
Works of Georg Dechant being referenced
Neurotrophin-3 promotes the cholinergic differentiation of sympathetic neurons
2000
Neurotrophins: structural relatedness and receptor interactions
1991
Roles of neurotrophin-3 during early development of the peripheral nervous system
1996
Nerve Growth Factor Regulates Expression of the Nerve Growth Factor Receptor Gene in Adult Sensory Neurons
1990
Neurotrophins
2003
Signalling through the neurotrophin receptor p75NTR
1997
Early Expression of the Nerve Growth Factor Receptor ctrkA in Chick Sympathetic and Sensory Ganglia
1995
Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
1990
Brain‐derived Neurotrophic Factor is a Survival Factor for Cultured Rat Cerebellar Granule Neurons and Protects them Against Glutamate‐induced Neurotoxicity
1993
The p75 Neurotrophin Receptor Negatively Modulates Dendrite Complexity and Spine Density in Hippocampal Neurons
2005
Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system
2001
Opposing Functions of GDNF and NGF in the Development of Cholinergic and Noradrenergic Sympathetic Neurons
2002
The neurotrophin receptor p75NTR: novel functions and implications for diseases of the nervous system
2002
Molecular interactions between neurotrophin receptors
2001
Neurotrophin receptors
1994
A crucial role for neurotrophin-3 in oligodendrocyte development
1994 Nature
Specific high-affinity receptors for neurotrophin-3 on sympathetic neurons
1993
Expression and binding characteristics of the BDNF receptor chick trkB
1993
Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.
1992
Complete Deletion of the Neurotrophin Receptor p75NTRLeads to Long-Lasting Increases in the Number of Basal Forebrain Cholinergic Neurons
2002
The Neurotrophin Receptor p75 Binds Neurotrophin-3 on Sympathetic Neurons with High Affinity and Specificity
1997
A splice variant of the neurotrophin receptor trkB with increased specificity for brain-derived neurotrophic factor.
1996