Citation Impact
Citing Papers
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium
2011
Catalyst- and solvent-free synthesis of highly functionalized octahydro-imidazo[1,2-a]quinolin-6-ones via a one-pot sequential four-component reaction in melt conditions
2013
Targeting the dopamine D2receptor in schizophrenia
2006
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Glecaprevir and Pibrentasvir in Patients with HCV and Severe Renal Impairment
2017
Effects of the Antifungal Agents on Oxidative Drug Metabolism
2000
Correction of Permeability with Pore Radius of Tight Junctions in Caco-2 Monolayers Improves the Prediction of the Dose Fraction of Hydrophilic Drugs Absorbed by Humans
2004
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Assessment of Chimeric Mice with Humanized Liver as a Tool for Predicting Circulating Human Metabolites
2010
Cytochrome P-450 Polymorphisms and Response to Clopidogrel
2008 Standout
Long-Acting Risperidone
2004
Glioblastoma and Other Malignant Gliomas
2013 Standout
Clinical Relevance of the Pharmacokinetic Interactions of Azole Antifungal Drugs with Other Coadministered Agents
2009
Boosted regression trees, multivariate adaptive regression splines and their two-step combinations with multiple linear regression or partial least squares to predict blood–brain barrier passage: A case study
2008
Efficacy of Direct-Acting Antiviral Combination for Patients With Hepatitis C Virus Genotype 1 Infection and Severe Renal Impairment or End-Stage Renal Disease
2016
Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis—State of the Art: Cystic Fibrosis Foundation Consensus Conference
2003
Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology
2013
Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
2007
Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists
2009
Clinically relevant drug interactions with antiepileptic drugs
2005
Human hepatocytes: Isolation, cryopreservation and applications in drug development
2007
Removal of trace organics by MBR treatment: The role of molecular properties
2011
The food metabolome: a window over dietary exposure
2014
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
Microfluidic organs-on-chips
2014 Standout
Microbial degradation of petroleum hydrocarbons
2016 Standout
Integration ofin silicoandin vitroplatforms for pharmacokinetic–pharmacodynamic modeling
2010
Metabolomics: beyond biomarkers and towards mechanisms
2016 Standout
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
2012 Standout
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
2007
Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins
2012
A review on emerging contaminants in wastewaters and the environment: Current knowledge, understudied areas and recommendations for future monitoring
2014 Standout
Occurrence and fate of emerging contaminants in municipal wastewater treatment plants from different geographical regions-a review
2017 Standout
tBuLi‐Mediated One‐Pot Direct Highly Selective Cross‐Coupling of Two Distinct Aryl Bromides
2015 StandoutNobel
Occurrence of pharmaceutical compounds in urban wastewater: Removal, mass load and environmental risk after a secondary treatment—A review
2012 Standout
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
2017
A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment
2014 Standout
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Stereochemical comparison of nebivolol with other β‐blockers
2007
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis
2013 Standout
A microfluidic hepatic coculture platform for cell-based drug metabolism studies
2009
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
New atypical antipsychotics for schizophrenia: iloperidone
2010
Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis
2003 Standout
Nickel‐Catalyzed Cross‐Coupling of Organolithium Reagents with (Hetero)Aryl Electrophiles
2015 StandoutNobel
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Targeted Covalent Inhibitors for Drug Design
2016
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Collinearity: a review of methods to deal with it and a simulation study evaluating their performance
2012 Standout
Triazole antifungal agents drug–drug interactions involving hepatic cytochrome P450
2011
Human Pharmacogenomic Variations and Their Implications for Antifungal Efficacy
2006
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Recent advances in the synthesis of pyrroles by multicomponent reactions
2014 Standout
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
The Many Roles for Fluorine in Medicinal Chemistry
2008 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
2017 StandoutNobel
Humanized mice with ectopic artificial liver tissues
2011
Metabolism-guided drug design
2012
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America
2016 Standout
Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases
2010
The Role of Histamine H1 and H4 Receptors in Atopic Dermatitis: From Basic Research to Clinical Study
2014
Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America
2015 Standout
Optimisation of Itraconazole Therapy Using Target Drug Concentrations
1998
Nebivolol
2006
Predicting ADME properties and side effects: the BioPrint approach.
2003
Oral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability
2012
Site-Specific Traceless Coupling of Potent Cytotoxic Drugs to Recombinant Antibodies for Pharmacodelivery
2012
Chiral Diarylmethanes via Copper-Catalyzed Asymmetric Allylic Arylation with Organolithium Compounds
2015 StandoutNobel
EASL Recommendations on Treatment of Hepatitis C 2018
2018 Standout
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of America
2008 Standout
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development
2014 StandoutNobel
Photoredox Catalysis in Organic Chemistry
2016 Standout
Claudins and the Modulation of Tight Junction Permeability
2013 Standout
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Paliperidone for schizophrenia
2008
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
CF2H, a Hydrogen Bond Donor
2017 Standout
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
2011
Clinical Practice Guidelines for the Management of Patients with Histoplasmosis: 2007 Update by the Infectious Diseases Society of America
2007 Standout
Works of Geert Mannens being referenced
Clinical Pharmacology of Alcaftadine, a Novel Antihistamine for the Prevention of Allergic Conjunctivitis
2011
Absorption, metabolism, and excretion of risperidone in humans.
1993
Evaluation of the Pharmacokinetics and Renal Excretion of Simeprevir in Subjects with Renal Impairment
2015
Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes
2003
4-Methyl-1,2,4-triazol-3-yl heterocycle as an alternative to the 1-methylimidazol-5-yl moiety in the Farnesyltransferase inhibitor ZARNESTRA ™
2003
Substituted azoloquinolines and -quinazolines as new potent farnesyl protein transferase inhibitors
2003
Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin*
1995
EXPRESSION AND INDUCTION POTENTIAL OF CYTOCHROMES P450 IN HUMAN CRYOPRESERVED HEPATOCYTES
2005
Absorption, Metabolism, and Excretion of Darunavir, a New Protease Inhibitor, Administered Alone and with Low-Dose Ritonavir in Healthy Subjects
2009
Absorption, Metabolism, and Excretion of Oral 14C Radiolabeled Ibrutinib: An Open-Label, Phase I, Single-Dose Study in Healthy Men
2014
5-Imidazolyl-quinolinones, -quinazolinones and -benzo-azepinones as farnesyltransferase inhibitors
2003
Plasma protein binding of risperidone and its distribution in blood
1994
CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes
2002
Strategies for Absorption Screening in Drug Discovery and Development
2001
Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
2008
Which Human Metabolites Have We MIST? Retrospective Analysis, Practical Aspects, and Perspectives For Metabolite Identification and Quantification in Pharmaceutical Development
2009
Clinical Pharmacokinetics of Nebivolol
1991
Evaluation of Three State-of-the-Art Metabolite Prediction Software Packages (Meteor, MetaSite, and StarDrop) through Independent and Synergistic Use
2011