Citation Impact
Citing Papers
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier
1994
Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da
1988 StandoutNobel
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
The Genomic Identity of Different Strains of Mouse Scrapie Is Expressed in Hamsters and Preserved on Reisolation in Mice
1989
A 'unified theory' of prion propagation
1991 Nature
Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome
1989 StandoutNatureNobel
Asparagine-linked glycosylation of the scrapie and cellular prion proteins
1989
The Neurochemistry of Prion Diseases
1993
The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis
1991
Evidence for a secretory form of the cellular prion protein
1987 StandoutNobel
Structural Clues to Prion Replication
1994 StandoutScienceNobel
Identification of cellular proteins binding to the scrapie prion protein
1990 StandoutNobel
PrP genotypes and experimental scrapie in orally inoculated Suffolk sheep in the United States.
1997
Pathogenesis of scrapie is faster when infection is intraspinal instead of intracerebral
1987
Selective Neuronal Targeting in Prion Disease
1997 StandoutNobel
Transmissible and non-transmissible amyloidoses: autocatalytic post-translational conversion of host precursor proteins to β-pleated sheet configurations
1988 Nobel
Transmissible spongiform encephalopathies (TSE) virus-induced amyloidoses of the central nervous system (CNS)
1991
Eight prion strains have PrPSc molecules with different conformations
1998 Nobel
Coronavirus Pathogenesis
2011
Search for a Putative Scrapie Genome in Purified Prion Fractions Reveals a Paucity of Nucleic Acids
1991
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1997 StandoutNatureNobel
Mice devoid of PrP are resistant to scrapie
1993 Standout
Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein
1990 StandoutNatureNobel
The exceptionally small size of the scrapie agent
1966
Biochemical Differences among Scrapie-associated Fibrils Support the Biological Diversity of Scrapie Agents
1985
Replication of the Factor in Scrapie Material That Causes a Decrease in Polymorphonuclear Neutrophils
1973
Scrapie-Induced Changes in the Percentage of Polymorphonuclear Neutrophils in Mouse Peripheral Blood
1972
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
1997 StandoutNobel
Sedimentation characteristics of the scrapie agent from murine spleen and brain
1978 StandoutNobel
Transmissible spongiform encephalopathies: The threat of BSE to man
1990
Scrapie PrP 27-30 is a sialoglycoprotein
1985
Nature of the Scrapie Agent
1967 Nature
Measurement of the scrapie agent using an incubation time interval assay
1982 StandoutNobel
Sedimentation properties of the scrapie agent.
1977
Detection of the Scrapie Agent in Tissues of Normal Mice
1968 Nature
No Mouse PMN Leukocyte Depression after Inoculation with Brain Tissue from Multiple Sclerosis or Spongiform Encephalopathies
1974 StandoutNatureNobel
Properties of scrapie prion protein liposomes.
1988 StandoutNobel
Comparison of Scrapie and Transmissible Mink Encephalopathy in Hamsters. II. Clinical Signs, Pathology, and Pathogenesis
1975
Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
1994 StandoutNobel
Kuru with incubation periods exceeding two decades
1982 StandoutNobel
Search for Infectious Etiology in Chronic and Subacute Degenerative Diseases of the Central Nervous System
1967
Molecular characteristics of the major scrapie prion protein
1984 StandoutNobel
Oral Transmission of Kuru, Creutzfeldt-Jakob Disease, and Scrapie to Nonhuman Primates
1980
Unraveling prion diseases through molecular genetics
1989 StandoutNobel
Purification of the Scrapie Agent by Density Gradient Centrifugation
1984
Evidence for an essential DNA component in the Scrapie agent
1978 Nature
Scrapie: A transmissible and hereditary disease of sheep
1962
Viroids and prions.
1982
Partial purification of the scrapie agent from mouse brain by pressure disruption and zonal centrifugation in sucrose-sodium chloride gradients
1976 StandoutNobel
Resistance of the scrapie agent to formalin
1965
Toward Development of Assays for Scrapie-Specific Antibodies
1981 StandoutNobel
Biohazards of Investigations on the Transmissible Spongiform Encephalopathies
1980 StandoutNobel
GENETICS OF PRIONS
1997 StandoutNobel
Electrophoretic properties of the scrapie agent in agarose gels.
1980 StandoutNobel
Viremia in Experimental Creutzfeldt-Jakob Disease
1978 Science
Properties of the scrapie agent-endomembrane complex from hamster brain
1976
Inoculation of Voles, Chinese Hamsters, Gerbils and Guinea-pigs with Scrapie Brain Material
1972
Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity
1996 StandoutNobel
ENCEPHALOPATHY IN MICE PRODUCED BY INOCULATION WITH SCRAPIE BRAIN MATERIAL
1961
The future of cloning
1999 StandoutNatureNobel
Scrapie in mice
1973
Pathogenesis of mouse scrapie
1983
Characteristics of a Short Incubation Model of Scrapie in the Golden Hamster
1977
Evidence of mitochondrial involvement in scrapie infection
1989
Scrapie: Effect of Dh gene on incubation period of extraneurally injected agent
1972
Partial purification and evidence for multiple molecular forms of the scrapie agent
1978 StandoutNobel
Biological Evidence that Scrapie Agent Has an Independent Genome
1987
Characterization of Scrapie Infection in Mouse Neuroblastoma Cells
1987
Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]
1987 StandoutNobel
Brain tissue from persons dying of creutzfeldt‐jakob disease causes scrapie‐like encephalopathy in goats
1980 StandoutNobel
Susceptibility of Scrapie Agent to Ionizing Radiation
1969 Nature
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
DNA Synthesis in Scrapie-Affected Mouse Brain
1967
Nature of the Scrapie Agent: Self-replication and Scrapie
1967 Nature
Identification of a Protein That Purifies with the Scrapie Prion
1982 StandoutScienceNobel
Experimental Scrapie in the Mouse
1963
Membrane-free scrapie activity
1978
The Scrapie Agent: “A Virus by Any Other Name”
1991
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
Temporary and Permanent Modifications to a Single Strain of Mouse Scrapie on Transmission to Rats and Hamsters
1987
RESISTANCE OF THE SCRAPIE AGENT TO INACTIVATION BY PSORALENS
1983
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
1997 StandoutNobel
Unconventional Viruses and the Origin and Disappearance of Kuru
1977 ScienceNobel
Propagation of prion strains through specific conformers of the prion protein
1997 StandoutNobel
Prions
1998 StandoutNobel
Reversible Chemical Modification of the Scrapie Agent
1981 StandoutScienceNobel
Physical properties of the Creutzfeldt-Jakob disease agent
1989
Scrapie: A Prototype Slow Infection
1972
Genetical control of the concentration of ME7 scrapie agent in the brain of mice
1969
Gel electrophoresis and glass permeation chromatography of the hamster scrapie agent after enzymatic digestion and detergent extraction
1980 StandoutNobel
Unusual Topogenic Sequence Directs Prion Protein Biogenesis
1990 StandoutScienceNobel
Immunohistochemical demonstration of glial fibrillary acidic protein in scrapie
1983
Detection of the Scrapie Agent in Tissues of Normal Mice with Special Reference to the Possibility of Accidental Laboratory Contamination
1971
Thiocyanate and hydroxyl ions inactivate the scrapie agent.
1981 StandoutNobel
Scrapie in Mice. The Stability of the Agent to Various Suspending Media, pH and Solvent Extraction
1965
Separation and properties of cellular and scrapie prion proteins.
1986 StandoutNobel
Towards Purification of the Scrapie Agent
1983
Virologic and Neurohistologic Findings in Dairy Goats Affected with Natural Scrapie
1980
Scrapie infectious agent is virus-like in size and susceptibility to inactivation
1984 Nature
Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform.
1993
Is the scrapie agent a virus?
1976 Nature
A Novel Coronavirus from Patients with Pneumonia in China, 2019
2020 Standout
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins
1988 StandoutNobel
Inability to Transmit Scrapie by Transfection of Mouse Embryo Cells in vitro
1982
THE INFECTIVE PROCESS IN SCRAPIE
1968
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Transmission of Two Subacute Spongiform Encephalopathies of Man (Kuru and Creutzfeldt–Jakob Disease) to New World Monkeys
1971 StandoutNatureNobel
Experimental Scrapie in the Mouse: Electrophoretic and Sedimentation Properties of the Partially Purified Agent
1980 StandoutNobel
Scrapie incubation time can exceed natural lifespan
1975 Nature
A Preliminary Report on the Experimental Host Range of the Transmissible Mink Encephalopathy Agent
1969
Prions: Novel Infectious Pathogens
1984 StandoutNobel
Transmission of Scrapie in Hamsters
1985 StandoutNobel
Scrapie agent contains a hydrophobic protein.
1981
Conservation of infectivity in purified fibrillary extracts of scrapie-infected hamster brain after sequential enzymatic digestion or polyacrylamide gel electrophoresis.
1990 Nobel
Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]
1987
The Relative Susceptibility of Sheep, Goats and Mice to Two Types of the Goat Scrapie Agent
1966
Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters.
1992 StandoutNobel
An analysis of natural scrapie in suffolk sheep
1965
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells.
1990 StandoutNobel
Transmissible mink encephalopathy: pathogenesis and nature of the aetiological agent
1972
In vitro Replication of Scrapie Agent in a Neuronal Model: Infection of PC12 Cells
1984
Is the Scrapie Agent a Viroid?
1972
Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease.
1987
Natural Infection of Suffolk Sheep with Scrapie Virus
1982
STUDIES ON DNA FROM NORMAL AND SCRAPIE‐AFFECTED MOUSE BRAIN
1972
Prion liposomes
1990 StandoutNobel
A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7
1969
Modification of a Strain of Mouse-adapted Scrapie by Passage through Rats
1968
Antibodies to a scrapie prion protein
1984 StandoutNatureNobel
Purified prion proteins and scrapie infectivity copartition into liposomes.
1987 StandoutNobel
Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins
1987
Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes
1979
Conservation of the cellular gene encoding the scrapie prion protein
1986 StandoutNobel
Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
1990 StandoutScienceNobel
Transmission experiments with a scrapie-like encephalopathy of mink
1970
Experimental Subacute Spongiform Virus Encephalopathies in Primates and Other Laboratory Animals
1973 StandoutScienceNobel
Works of G.C. Millson being referenced
Absence of Eclipse Phase in Scrapie Mice
1972
Experimental Transmission of Scrapie To Goats and Sheep By the Oral Route
1961
Glycoprotein biosynthesis in normal and scrapie-affected mouse brain
1973
The Intracellular Location of the Agent of Mouse Scrapie
1964
Involvement of protein in scrapie agent infectivity
1983
Changes in a Protein-Nucleic Acid Complex from Synaptic Plasma Membrane of Scrapie-Infected Mouse Brain
1976
Early distribution of radioactive liposomes and scrapie infectivity in mouse tissues following administration by different routes
1979
Biochemical and histopathological changes in the brains of mice inoculated with scrapie by the intraperitoneal route
1971
Distribution of the scrapie agent in the tissues of experimentally inoculated goats
1962
Experimental Production of Scrapie in Goats
1959
An Examination of the Action of Whole Blood, Blood Cells or Serum on the Goat Scrapie Agent
1964
Studies on the Heat Stability and Chromatographic Behaviour of the Scrapie Agent
1964
Glycosidase histochemistry in normal and scrapie mice, rats, sheep and goats
1968
Attempts to release the scrapie agent from tissue debris
1967
INTERSPECIES TRANSMISSION OF SCRAPIE-LIKE DISEASES
1975
An experimental examination of the scrapie agent in cell membrane mixtures
1971
DISTRIBUTION AND ACTIVATION OF LYSOSOMAL ENZYME ACTIVITIES IN SUBCELLULAR COMPONENTS OF NORMAL AND SCRAPIE‐AFFECTED MOUSE BRAIN
1966
An experimental examination of the scrapie agent in cell membrane mixtures
1971
Some biochemical aspects of mouse scrapie
1967
Search for Scrapie-specific RNA and Attempts to Detect an Infectious DNA or RNA
1976
PROTEIN SYNTHESIS IN NORMAL AND SCRAPIE MOUSE BRAIN
1968
LYSOSOMAL ENZYMES IN NORMAL AND SCRAPIE MOUSE BRAIN
1965
Failure of fluorocarbon treatment to affect sensitivity of scrapie agent to ultraviolet light
1977
Further Experiments on the Comparative Potency of Tissue Extracts from Mice Infected with Scrapie
1964
Further Observations on the Experimental Production of Scrapie in Goats and Sheep
1960
Immunoglobulin G concentrations in the sera of Herdwick sheep with natural scrapie
1979
An experimental examination of the scrapie agent in cell membrane mixtures
1971
Scrapie Produced Experimentally in Goats With Special Reference To the Clinical Syndrome
1961
Disinfection studies with two strains of mouse-passaged scrapie agent
1983
A comparison of the biochemical changes induced in mouse brain by cuprizone toxicity and by scrapie infection
1974
Defective Replication of Porcine Transmissible Gastroenteritis Virus in a Continuous Cell Line
1984
Further studies of the infectivity and stability of extracts and homogenates derived from scrapie affected mouse brains
1969
Further Experimental Observations on Scrapie
1961
Observations on the Comparative Infectivity of Cellular Fractions Derived from Homogenates of Mouse-scrapie Brain
1963
Can Scrapie Titres be Calculated Accurately from Incubation Periods?
1983
Infection of a cell line of mouse L fibroblasts with scrapie agent
1976 Nature
Biochemical and Haematological Observations on the Blood and Cerebrospinal Fluid of Clinically Healthy and Scrapie-Affected Goats
1960
GLYCOSIDASES IN NORMAL AND SCRAPIE MOUSE BRAIN
1973
The Membrane Location of Scrapie Infectivity
1976