Citation Impact
Citing Papers
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Cloning, Chromosomal Localization, and Functional Analysis of the Murine Estrogen Receptor β
1997
Expression of the SV40 promoter in fission yeast: Identification and characterization of an AP-1-like factor
1988 StandoutNobel
Structural Organization and Expression of the Mouse Estrogen Receptor
1987
Enantioselective synthesis of β-amino esters and its application to the synthesis of the enantiomers of the antidepressant Venlafaxine
2006
Identification of two transactlvation domains in the mouse oestrogen receptor
1989
The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain
1989
The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements
1988
Estrogen Receptor β: Re-evaluation of Estrogen and Antiestrogen Signaling
1998
Identification and Estrogen Induction of Two Estrogen Receptors (ER) Messenger Ribonucleic Acids in the Rainbow Trout Liver: Sequence Homology with other ERs
1989
Estradiol Inhibits Transcription of the Human Glycoprotein Hormone α-Subunit Gene Despite the Absence of a High Affinity Binding Site for Estrogen Receptor
1991
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator
1988
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
A chimeric Cre recombinase inducible by synthetic,but not by natural ligands of the glucocorticoid receptor
1998
Identification of constitutive and steroid-dependent transactivation domains in the mouse oestrogen receptor
1989
The human estrogen receptor has two independent nonacidic transcriptional activation functions
1989
Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist
1989 Nature
Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif
1988
Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast
1992
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
1997 StandoutNature
Lineage dependency and lineage-survival oncogenes in human cancer
2006
Beyond zinc fingers: steroid hormone receptors have a novel structural motif for DNA recognition
1991
Identification of a Third Autonomous Activation Domain within the Human Estrogen Receptor
1997
MINIREVIEW: Estrogen Receptor Variants in Clinical Breast Cancer
1991
The Human Androgen Receptor: Complementary Deoxyribonucleic Acid Cloning, Sequence Analysis and Gene Expression in Prostate
1988
TheXenopus laevisEstrogen Receptor: Sequence Homology with Human and Avian Receptors and Identification of Multiple Estrogen Receptor Messenger Ribonucleic Acids*
1987
The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex
1990
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element
1989 Nature
Phosphorylation on Tyrosine ofin VitroSynthesized Human Estrogen Receptor Activates Its Hormone Binding
1989
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Estradiol-Stimulated Proteolytic Cleavage of the Estrogen Receptor in Mouse Uterus
1988
Influence of Estrogens on Mouse Uterine Epidermal Growth Factor Precursor Protein and Messenger Ribonucleic Acid
1988
Estrogen Regulates the Synthesis of Epidermal Growth Factor in Mouse Uterine Epithelial Cells
1990
Uterine Insulin-Like Growth Factor-1: Regulation of Expression and Its Role in Estrogen-Induced Uterine Proliferation*
1990
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically
1992
Different Regions in Activation Function-1 of the Human Estrogen Receptor Required for Antiestrogen- and Estradiol-dependent Transcription Activation
1996
Estrogen Receptors, Estradiol, and Diethylstilbestrol in Early Development: The Mouse as a Model for the Study of Estrogen Receptors and Estrogen Sensitivity in Embryonic Development of Male and Female Reproductive Tracts*
1993
Oestrogen receptor B-region polymorphism and spontaneous abortion in women with breast cancer
1990
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm
1993 StandoutNobel
The N-terminal region of the chicken progesterone receptor specifies target gene activation
1988 Nature
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
The estrogen receptor gene: Promoter organization and expression
1997
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
1995 StandoutNature
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific
1989
Steroid receptors
1989
The war of the whorls: genetic interactions controlling flower development
1991 StandoutNature
The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen
1998 Standout
Multiple and cooperative trans-activation domains of the human glucocorticoid receptor
1988
Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences
1989 StandoutNatureNobel
Molecular basis of agonism and antagonism in the oestrogen receptor
1997 StandoutNature
In vivo and in vitro phosphorylation of the human estrogen receptor
1995
The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function
1988
Expression of active hormone and DNA-binding domains of the chicken progesterone receptor in E. coli.
1989
Agonistic Effect of Tamoxifen Is Dependent on Cell Type, ERE-Promoter Context, and Estrogen Receptor Subtype: Functional Difference between Estrogen Receptors α and β
1997
A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor
1988
Differential Recognition of Target Genes by Nuclear Receptor Monomers, Dimers, and Heterodimers*
1994
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor
1994
Structure and Function of Estrogen Receptors
1995
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
1990
The human oestrogen receptor functions in yeast
1988 Nature
Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action
2004
Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo.
1995
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
1989 StandoutNobel
Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells
1995
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
1991 StandoutNature
Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein
1988 Nature
Steroid hormone receptors compete for factors that mediate their enhancer function
1989
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer
1988 Standout
A novel mediator between activator proteins and the RNA polymerase II transcription apparatus
1990 StandoutNobel
Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells
1989 StandoutNatureNobel
Gene regulation by steroid hormones
1989 Standout
Mechanisms of Signal Transduction to the Cell Nucleus
1990
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
1993 StandoutNobel
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.
1995 StandoutNobel
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
2000 StandoutNobel
Correlation between low levels of estrogen receptors and estrogen responsiveness in two rat osteoblast-like cell lines
1994
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Determinants of target gene specificity for steroid/thyroid hormone receptors
1989
Estrogen Receptor Domains E and F: Role in Dimerization and Interaction with Coactivator RIP-140
1999
Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone.
1993
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
The Steroid and Thyroid Hormone Receptor Superfamily
1988 StandoutScience
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Nuclear Receptor-Binding Sites of Coactivators Glucocorticoid Receptor Interacting Protein 1 (GRIP1) and Steroid Receptor Coactivator 1 (SRC-1): Multiple Motifs with Different Binding Specificities
1998
Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens.
1995
Basic Guide to the Mechanisms of Antiestrogen Action
1998
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
1999 Standout
Properties of a high-affinity DNA binding site for estrogen receptor.
1988
Recent developments in indole ring synthesis—methodology and applications
2000 Standout
Generation and reproductive phenotypes of mice lacking estrogen receptor β
1998 StandoutNobel
Sequence-specific DNA binding by glucocorticoid receptor "zinc finger peptides".
1990
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.
1996
Initiation by Yeast RNA Polymerase II at the Adenoviral Major Late Promoter in Vitro
1989 StandoutScienceNobel
Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator.
1996
Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription
1994 Science
Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast.
1993
The Molecular Pharmacology of SERMs
1999
Molecular characterization by mass spectrometry of the human estrogen receptor ligand-binding domain expressed in Escherichia coli.
1995
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.
1992
Ontogeny of Steroid Receptors in the Reproductive System
1986
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.
1990
Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ
1995
Identification of charged residues in an N-terminal portion of the hormone-binding domain of the human estrogen receptor important in transcriptional activity of the receptor.
1993
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
Regulation of Inducible and Tissue-Specific Gene Expression
1987 Science
Genomic organization of the human oestrogen receptor gene.
1988
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).
1992
Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction
1992 StandoutScience
Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.
1992
The N-terminal DNA-binding ‘zinc finger’ of the oestrogen and glucocorticoid receptors determines target gene specificity.
1988
Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes
1990
Increased Expression of Estrogen Receptor-β mRNA in Male Blood Vessels After Vascular Injury
1998
Purification and lipid-layer crystallization of yeast RNA polymerase II.
1990 StandoutNobel
Mediator protein mutations that selectively abolish activated transcription
1999 StandoutNobel
Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily
1995 StandoutScience
Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors.
1992
Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.
1989
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.
1993
The t4 Activation Domain of the Thyroid Hormone Receptor Is Required for Release of a Putative Corepressor(s) Necessary for Transcriptional Silencing
1995
Characterization and expression of a cDNA encoding the human androgen receptor.
1989
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
Nuclear receptors enhance our understanding of transcription regulation
1988
Evidence that the conserved region in the steroid binding domain of the glucocorticoid receptor is required for both optimal binding of hsp90 and protection from proteolytic cleavage. A two-site model for hsp90 binding to the steroid binding domain.
1990
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
1995 StandoutScience
Solution structure of the DMA-binding domain of the oestrogen receptor
1990 Nature
The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties.
1989
Identification of the DNA Binding Site for NGFI-B by Genetic Selection in Yeast
1991 Science
Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene.
1993
A genetic approach to trace neural circuits
1999 StandoutNobel
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
1999 StandoutNobel
Molecular phenotyping for analyzing subtle genetic effects in mice: Application to an angiotensinogen gene titration
2002 StandoutNobel
Works of Gary Stack being referenced
2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: synthesis and antidepressant activity
1990
Functional domains of the human estrogen receptor
1987
Development of a New Practical Synthesis of a 5-HT2C Receptor Agonist
2010
Estrogen-Stimulated Deoxyribonucleic Acid Synthesis: A Ratchet Model for the Prereplicative Period*
1985
Direct Mitogenic Effect of Estrogen on the Prepuberal Rat Uterus: Studies on Isolated Nuclei*
1984
New generation dopaminergic agents 4. Exploiting the 2-methyl chroman scaffold. Synthesis and evaluation of two novel series of 2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indole and indol-8-one derivatives
1998
The Ontogeny of Estrogen Responsiveness Reexamined: The Differential Effectiveness of Diethylstilbestrol and Estradiol on Uterine Deoxyribonucleic Acid Synthesis in Neonatal Rats*
1983
Introduction of estrogen-responsiveness into mammalian cell lines
1986