Citation Impact
Citing Papers
STIM1, an essential and conserved component of store-operated Ca2 + channel function
2005 Standout
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
A hexahistidine-Zn 2+ -dye label reveals STIM1 surface exposure
2007 StandoutNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
2003 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics
2006 StandoutNobel
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Reversible Desensitization of Inositol Trisphosphate-induced Calcium Release Provides a Mechanism for Repetitive Calcium Spikes
1996
Long-term uncoupling of chloride secretion from intracellular calcium levels by lns(3,4,5,6)P4
1994 StandoutNatureNobel
Control of astrocyte Ca2+ oscillations and waves by oscillating translocation and activation of protein kinase C
2001
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Differential modulation of the phases of a Ca2+ spike by the store Ca2+‐ATPase in human umbilical vein endothelial cells
1998
STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx
2005 Standout
The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors
1992
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
2003 Standout
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Calcium release‐activated calcium current in rat mast cells.
1993
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
TRP, TRPL and trouble in photoreceptor cells
1998
The TRPC3 Channel Has a Large Internal Chamber Surrounded by Signal Sensing Antennas
2006
TRP channels and lipids: from Drosophila to mammalian physiology
2006
Store-Operated Ca2+ Entry
1999
Prostaglandin E2‐induced sensitization of bradykinin‐evoked responses in rat dorsal root ganglion neurons is mediated by cAMP‐dependent protein kinase A
2000
2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3
2004
TRPC1: store-operated channel and more
2005
Nonalcoholic Fatty Liver Disease
2002 Standout
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma
2010
Role of the Cytoskeleton in Calcium Signaling in NIH 3T3 Cells
1997
Modifications of CD8+ T Cell Function during In Vivo Memory or Tolerance Induction
1998
Ca2+ Pools and Cell Growth: Arachidonic Acid Induces Recovery of Cells Growth-arrested by Ca2+ Pool Depletion
1996
Canonical Transient Receptor Potential Channels Promote Cardiomyocyte Hypertrophy through Activation of Calcineurin Signaling
2006
Calcium store contents control the expression of TRPC1, TRPC3 and TRPV6 proteins in LNCaP prostate cancer cell line
2006
Autoantibodies against TRPC3 and ryanodine receptor in myasthenia gravis
2008
Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai
2006 Nature
Rat basophiliv leukemia cells as model system for inositol 1,4,5-trisphosphate receptor IV, a receptor of the type II family: functional comparison and immunological detection
1995
Ca2+ Modulation of Ca2+ Release-Activated Ca2+ Channels Is Responsible for the Inactivation of Its Monovalent Cation Current
2004
Inositol 1,3,4,5-tetrakisphosphate activates an endothelial Ca2+-permeable channel
1992 Nature
Phosphoinositide Regulation of TRP Channels
2014
Calcium and Hormone Action
1994
A C. elegans Sperm TRP Protein Required for Sperm-Egg Interactions during Fertilization
2003
Store-Operated Calcium Channels
2005 Standout
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Microscopic properties of elementary Ca2+ release sites in non-excitable cells
2000 StandoutNobel
Separation and Characterization of Currents through Store-operated CRAC Channels and Mg2+-inhibited Cation (MIC) Channels
2002
Depletion of intracellular calcium stores activates a calcium current in mast cells
1992 StandoutNature
Structural Conservation of the Genes Encoding CaT1, CaT2, and Related Cation Channels
2001
The TRPM7 channel is inactivated by PIP2 hydrolysis
2002
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
TRP channels as cellular sensors
2003 StandoutNature
Differential Involvement of Vacuolar H+-ATPase in the Refilling of Thapsigargin- and Agonist-Mobilized Ca2+ Stores
2000
Orai1 and STIM Reconstitute Store-operated Calcium Channel Function
2006
Cytosolic calcium transients: Spatial localization and role in drosophila photoreceptor cell function
1994 StandoutNobel
Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF
1999
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Phosphoinositide regulation of TRPV1 revisited
2015
Ca2+ release induced by inositol 1,4,5-trisphosphate is a steady-state phenomenon controlled by luminal Ca2+ in permeabilized cells
1992 Nature
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Potentiation and inhibition of Ca2+ release‐activated Ca2+ channels by 2‐aminoethyldiphenyl borate (2‐APB) occurs independently of IP3 receptors
2001
The Virtual Cell: a software environment for computational cell biology
2001
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer
2001
The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate
1998 Standout
Isolation of mutant T lymphocytes with defects in capacitative calcium entry
1995
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Mechanotransduction and chemosensitivity of two major classes of bladder afferents with endings in the vicinity to the urothelium
2009
Capacitative calcium entry is inhibited in vascular endothelial cells by disruption of cytoskeletal microfilaments
1997
CRAC channels: activation, permeation, and the search for a molecular identity
2003
trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry
1996
Selective Association of TRPC Channel Subunits in Rat Brain Synaptosomes
2002
Calcium oscillations increase the efficiency and specificity of gene expression
1998 StandoutNature
Capacitative calcium entry channels
1999
TRP channels: An overview
2005
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Calmodulin Modulates the Delay Period between Release of Calcium from Internal Stores and Activation of Calcium Influx via Endogenous TRP1 Channels
2002
12 Store-operated calcium channels
1999
Initiation of IP3-mediated Ca2+ waves in Xenopus oocytes
1999
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Protein Kinase C as a Molecular Machine for Decoding Calcium and Diacylglycerol Signals
1998
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Orai1 is an essential pore subunit of the CRAC channel
2006 StandoutNature
Receptor-specific messenger oscillations
2001 Nature
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch
2013
Structure and gating mechanism of the transient receptor potential channel TRPV3
2018
Interaction of STIM1 with Endogenously Expressed Human Canonical TRP1 upon Depletion of Intracellular Ca2+ Stores
2006
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Structure and function of inositol triphosphate receptors
1991
Spatially and Functionally Distinct Ca 2+ Stores in Sarcoplasmic and Endoplasmic Reticulum
1997 Science
Inositol phosphate receptors and calcium disposition in the brain
1992
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
Autophosphorylation of inositol 1,4,5-trisphosphate receptors.
1992
Block of Ca 2+ Wave and Ca 2+ Oscillation by Antibody to the Inositol 1,4,5-Trisphosphate Receptor in Fertilized Hamster Eggs
1992 StandoutScienceNobel
Internal Ca2+ release in yeast is triggered by hypertonic shock and mediated by a TRP channel homologue
2002
The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency.
1994
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension
2004
Roles of cytoplasmic Ca2+ and intracellular Ca2+ stores in induction and suppression of apoptosis in S49 cells
1997
The TRP Superfamily of Cation Channels
2005
TRPC1, a human homolog of a Drosophila store-operated channel.
1995
Control of Ca2+ entry into HL60 and U937 human leukaemia cells by the filling state of the intracellular Ca2+ stores
1993
IP 3 Receptor: Localization to Plasma Membrane of T Cells and Cocapping with the T Cell Receptor
1992 Science
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Smoothly graded Ca2+ release from inositol 1,4,5-trisphosphate-sensitive Ca2+ stores.
1994
Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10‐CFTR2.
1997 StandoutNobel
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Magnetic fields increase cell survival by inhibiting apoptosis via modulation of Ca 2+ influx
1999
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Store-Operated Calcium Channels: How Do We Measure Them, and Why Do We Care?
2004
Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells.
1993
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Luminal Ca2+ promoting spontaneous Ca2+ release from inositol trisphosphate‐sensitive stores in rat hepatocytes.
1992
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane
2005 StandoutNature
The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2
1993 StandoutNobel
Ca2+ influx induced by the Ca2+-ATPase inhibitors 2,5-di-(t-butyl)-1,4-benzohydroquinone and thapsigargin in bovine adrenal chromaffin cells
1992
Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues
1995
Alteration of Stimulus-Specific Guard Cell Calcium Oscillations and Stomatal Closing in Arabidopsis det3 Mutant
2000 StandoutScienceNobel
The path of calcium in cytosolic calcium oscillations: a unifying hypothesis.
1991
Chemistry of Inositol Lipid Mediated Cellular Signaling
1995
STIM1 has a plasma membrane role in the activation of store-operated Ca 2+ channels
2006
Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor.
1992
The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor.
1992
Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation
2009
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Activation and Cellular Localization of the Cyclosporine A-sensitive Transcription Factor NF-AT in Skeletal Muscle Cells
1998
Calcium Signaling Mechanisms in T Lymphocytes
2001
Assessment of the Role of the Inositol 1,4,5-Trisphosphate Receptor in the Activation of Transient Receptor Potential Channels and Store-operated Ca2+ Entry Channels
2001
TRP Channels
2007 Standout
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Purification and characterization of inositol-1,3,4-trisphosphate 5/6-kinase from rat liver using an inositol hexakisphosphate affinity column.
1992
Persistent intracellular calcium pool depletion by thapsigargin and its influence on cell growth.
1991
Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells.
1995
Oxidized glutathione causes sensitization of calcium release to inositol 1,4,5-trisphosphate in permeabilized hepatocytes
1992
Invited Review: Arteriolar smooth muscle mechanotransduction: Ca2+signaling pathways underlying myogenic reactivity
2001
Carbachol-activated muscarinic (M1 and M3) receptors transfected into Chinese hamster ovary cells inhibit trafficking of endosomes.
1991 StandoutNobel
Works of Gary S. Bird being referenced
Complex Actions of 2-Aminoethyldiphenyl Borate on Store-operated Calcium Entry
2008
Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1
2006
Native TRPC7 Channel Activation by an Inositol Trisphosphate Receptor-dependent Mechanism
2006
Role of inositol (1,4,5)trisphosphate in epidermal growth factor-induced Ca2+ signaling in A431 cells.
1991
Factors determining cirrhosis in alcoholic liver disease
1988
The Role of Canonical Transient Receptor Potential 7 in B-cell Receptor-activated Channels
2005
The Inositol Phosphate-Calcium Signaling System in Nonexcitable Cells
1993
cGMP is not required for capacitative Ca2+ entry in Jurkat T-lymphocytes
1996
The Ca2+-mobilizing Actions of a Jurkat Cell Extract on Mammalian Cells and Xenopus laevis Oocytes
1995
Obligatory Role of Src Kinase in the Signaling Mechanism for TRPC3 Cation Channels
2004
Canonical transient receptor potential TRPC7 can function as both a receptor- and store-operated channel in HEK-293 cells
2004
Negative Regulation of TRPC3 Channels by Protein Kinase C-Mediated Phosphorylation of Serine 712
2004
Calcium Oscillations
2010
Signaling Mechanism for Receptor-activated Canonical Transient Receptor Potential 3 (TRPC3) Channels
2003
Complex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels
2008
A Calmodulin/Inositol 1,4,5-Trisphosphate (IP3) Receptor-binding Region Targets TRPC3 to the Plasma Membrane in a Calmodulin/IP3 Receptor-independent Process
2003
Comparison of Human TRPC3 Channels in Receptor-activated and Store-operated Modes
2002
Mechanism of Inhibition of TRPC Cation Channels by 2-Aminoethoxydiphenylborane
2005
Expression Level of the Canonical Transient Receptor Potential 3 (TRPC3) Channel Determines Its Mechanism of Activation
2003
The TRPC3/6/7 subfamily of cation channels
2003
Signaling Pathways Underlying Muscarinic Receptor-induced [Ca2+] Oscillations in HEK293 Cells
2001
Role of the Phospholipase C-Inositol 1,4,5-Trisphosphate Pathway in Calcium Release-activated Calcium Current and Capacitative Calcium Entry
2001
Mutual Antagonism of Calcium Entry by Capacitative and Arachidonic Acid-mediated Calcium Entry Pathways
2001
Calcium mobilization by inositol phosphates and other intracellular messengers
1994
Activation of Ca2+ entry into acinar cells by a non-phosphorylatable inositol trisphosphate
1991 Nature
Role of Inositol Phosphates in the Actions of Substance P on NK1 Receptors in Exocrine Gl and Cells
1991
The signal for capacitative calcium entry
1993
Sustained Ca2+ signaling in mouse lacrimal acinar cells due to photolysis of “caged” glycerophosphoryl-myo-inositol 4,5-bisphosphate.
1992
Relationship between the calcium-mobilizing action of inositol 1,4,5-trisphosphate in permeable AR4-2J cells and the estimated levels of inositol 1,4,5-trisphosphate in intact AR4-2J cells
1991
Delayed “all-or-none” activation of inositol 1,4,5-trisphosphate-dependent calcium signaling in single rat hepatocytes.
1994
Effect of Inositol 1,3,4,5-Tetrakisphosphate on Inositol Trisphosphate-activated Ca2⁺ Signaling in Mouse Lacrimal Acinar Cells
1996
Role of cyclic GMP in the control of capacitative Ca2+ entry in rat pancreatic acinar cells
1995
In situ imaging of agonist-sensitive calcium pools in AR4-2J pancreatoma cells. Evidence for an agonist- and inositol 1,4,5-trisphosphate-sensitive calcium pool in or closely associated with the nuclear envelope.
1992
Inhibition of thapsigargin-induced calcium entry by microinjected guanine nucleotide analogues. Evidence for the involvement of a small G-protein in capacitative calcium entry.
1993
Mechanisms of capacitative calcium entry
2001
Mobilization of calcium by inositol trisphosphates from permeabilized rat parotid acinar cells. Evidence for translocation of calcium from uptake to release sites within the inositol 1,4,5-trisphosphate- and thapsigargin-sensitive calcium pool
1991
Human Trp3 forms both inositol trisphosphate receptor-dependent and receptor-independent store-operated cation channels in DT40 avian B lymphocytes
2001
Subcellular distribution of the calcium-storing inositol 1,4,5-trisphosphate-sensitive organelle in rat liver. Possible linkage to the plasma membrane through the actin microfilaments
1991
Spatial and temporal aspects of cellular calcium signaling
1996
Sinusoidal oscillations in intracellular calcium requiring negative feedback by protein kinase C.
1993
Cloning and expression of the human transient receptor potential 4 (TRP4) gene: localization and functional expression of human TRP4 and TRP3
2000
The mechanism for synergism between phospholipase C- and adenylylcyclase-linked hormones in liver. Cyclic AMP-dependent kinase augments inositol trisphosphate-mediated Ca2+ mobilization without increasing the cellular levels of inositol polyphosphates.
1991
Cloning and expression of the human transient receptor potential 4 (TRP4) gene: localization and functional expression of human TRP4 and TRP3
2000