Citation Impact
Citing Papers
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
2009 StandoutScience
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
2018 Science
Requirement of bic/microRNA-155 for Normal Immune Function
2007 StandoutScience
Ubiquitin Ligases: Structure, Function, and Regulation
2017
ZBTB1 is a determinant of lymphoid development
2011 StandoutNobel
Capturing Chromosome Conformation
2002 StandoutScience
Computational design of a protein crystal
2012
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
2013
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
2010 StandoutNobel
Cutting Edge: Ikaros Is a Regulator of Th2 Cell Differentiation
2009
The Ig Domain Protein CD9P-1 Down-regulates CD81 Ability to Support Plasmodium yoelii Infection
2009
Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs
2021
Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development
2008
Gene Recruitment of the Activated INO1 Locus to the Nuclear Membrane
2004
Positions of Potential:Nuclear Organization and Gene Expression
2001
Targeting the E3 ubiquitin ligases DCAF15 and cereblon for cancer therapy
2020
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
2012
Ikaros DNA-Binding Proteins as Integral Components of B Cell Developmental-Stage-Specific Regulatory Circuits
2007
The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity
2011
Building ubiquitination machineries: E3 ligase multi-subunit assembly and substrate targeting by PROTACs and molecular glues
2020
Nucleotide binding database NBDB – a collection of sequence motifs with specific protein-ligand interactions
2015
Targeting Nuclear Receptors with PROTAC degraders
2019
Phosfinder: a web server for the identification of phosphate-binding sites on protein structures
2011
Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI
2017
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Developmentally induced changes in transcriptional program alter spatial organization across chromosomes
2005
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Structure and assembly of filamentous bacteriophages
2014
The Human Transcription Factors
2018 Standout
Suprafacial Orientation of the SCFCdc4 Dimer Accommodates Multiple Geometries for Substrate Ubiquitination
2007
Predominant Interaction of Both Ikaros and Helios with the NuRD Complex in Immature Thymocytes
2007
Gfi1b alters histone methylation at target gene promoters and sites of γ‐satellite containing heterochromatin
2006
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Cysteine Scanning Mutagenesis and Disulfide Mapping Studies of the TatA Component of the Bacterial Twin Arginine Translocase
2007
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
NEDD8 and ubiquitin ligation by cullin-RING E3 ligases
2020
FOXP3 and scurfy: how it all began
2014 StandoutNobel
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Ikaros-Family Proteins: In Search of Molecular Functions During Lymphocyte Development
2005
FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease
2007
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Form follows function: the genomic organization of cellular differentiation
2004
An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors
2016
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
Structure‐Based Mechanism of Oleate Hydratase from Elizabethkingia meningoseptica
2015
Strategies to Investigate Ubiquitination in Huntington's Disease
2020
An E3 ligase guide to the galaxy of small-molecule-induced protein degradation
2021
Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation
2008
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Structural regulation of cullin-RING ubiquitin ligase complexes
2011
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
2016
Interchromosomal associations between alternatively expressed loci
2005 Nature
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes
2020
The Ikaros family in lymphocyte development
2017
High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy
2005 StandoutNobel
Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
2007 StandoutNobel
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
A Conserved GXXXG Motif in APH-1 Is Critical for Assembly and Activity of the γ-Secretase Complex
2004
Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery
2020
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
Keep Your Fingers Off My DNA: Protein–Protein Interactions Mediated by C2H2 Zinc Finger Domains
2008
3′‐end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation
2006 StandoutNobel
Essential Role of a GXXXG Motif for Membrane Channel Formation by Helicobacter pylori Vacuolating Toxin
2003
Analysis of the LAGLIDADG interface of the monomeric homing endonuclease I-DmoI
2004
CTCF: Master Weaver of the Genome
2009 Standout
Phosphate binding sites identification in protein structures
2010
Synthetic protein–protein interaction domains created by shuffling Cys 2 His 2 zinc‐fingers
2006
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Helix-packing motifs in membrane proteins
2006
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B–cell differentiation
2013
Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs
2004
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
Clockwise helical stacking of triphenylbenzene-based organogelator induced by peripheral chirality
2007
Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression
2007
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
A role for Dicer in immune regulation
2006 StandoutNobel
Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
2013
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Building and remodelling Cullin–RING E3 ubiquitin ligases
2013
Crystal Engineering of Self-Assembled Porous Protein Materials in Living Cells
2017 StandoutNobel
Functional π-Gelators and Their Applications
2014 Standout
RING Domain E3 Ubiquitin Ligases
2009 Standout
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Transcriptional Control of Early B Cell Development
2004
Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin Conjugates
2012
A role for Dicer in immune regulation
2006 StandoutNobel
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
ATP-Dependent Nucleosome Remodeling
2002
Designing Two-Dimensional Protein Arrays through Fusion of Multimers and Interface Mutations
2015 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells
2011 StandoutNobel
Principles of Ubiquitin-Dependent Signaling
2018
Structural analysis of the RSC chromatin-remodeling complex
2002 StandoutNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Works of Gary Kleiger being referenced
Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly
2021 Nature
Essential Role for Ubiquitin-Ubiquitin-Conjugating Enzyme Interaction in Ubiquitin Discharge from Cdc34 to Substrate
2011
NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway
2012
Detection of sequential polyubiquitylation on a millisecond timescale
2009 Nature
GXXXG and GXXXA Motifs Stabilize FAD and NAD(P)-binding Rossmann Folds Through Cα–H⋯O Hydrogen Bonds and van der Waals Interactions
2002
NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly
2020 Nature
Perilous journey: a tour of the ubiquitin–proteasome system
2014
Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding
2000
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin
2013
Selective Dimerization of a C2H2 Zinc Finger Subfamily
2003
Evaluation of a Diffusion-Driven Mechanism for Substrate Ubiquitination by the SCF-Cdc34 Ubiquitin Ligase Complex
2006
Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates
2009
3D Structure and Significance of the GΦXXG Helix Packing Motif in Tetramers of the E1β Subunit of Pyruvate Dehydrogenase from the Archeon Pyrobaculum aerophilum,
2001
GXXXG and AXXXA: Common α-Helical Interaction Motifs in Proteins, Particularly in Extremophiles
2002
Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways
2019