Citation Impact
Citing Papers
Endotoxemia and sepsis mortality reduction by non-anticoagulant–activated protein C
2007
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Increased Thrombopoiesis and Platelet Activation in Hantavirus-Infected Patients
2015 StandoutNobel
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis
2001
Mechanisms of Thrombus Formation
2008 Standout
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Management of Sepsis
2006
Inflammation and thrombosis
2003
Reconstitution of the Human Endothelial Cell Protein C Receptor with Thrombomodulin in Phosphatidylcholine Vesicles Enhances Protein C Activation
1999
Delivery materials for siRNA therapeutics
2013 Standout
The molecular basis of blood coagulation
1988 Standout
Severe Sepsis and Septic Shock
2013 Standout
Atypical Hemolytic–Uremic Syndrome
2009
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective
2003
Complement: a key system for immune surveillance and homeostasis
2010 Standout
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Non-viral vectors for gene-based therapy
2014 Standout
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
The Protein C Pathway
2003
From evidence to clinical practice: Effective implementation of therapeutic hypothermia to improve patient outcome after cardiac arrest*
2006
Systemic Lupus Erythematosus
2011 Standout
Hydrocortisone Therapy for Patients with Septic Shock
2008 Standout
Resistance to Activated Protein C as a Basis for Venous Thrombosis
1994 Standout
Prevention of Venous Thromboembolism
2004 Standout
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Heparin prevents antiphospholipid antibody–induced fetal loss by inhibiting complement activation
2004
The Pathophysiology and Treatment of Sepsis
2003 Standout
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
2001 Standout
Cytoprotective protein C pathways and implications for stroke and neurological disorders
2011
Disseminated Intravascular Coagulation
1999 Standout
Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans
1997
The immunopathology of sepsis and potential therapeutic targets
2017 Standout
Points of control in inflammation
2002 StandoutNature
Recurrent miscarriage
2006 Standout
Basic mechanisms and pathogenesis of venous thrombosis
2009
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Spatial and temporal dynamics of the endothelium
2005
Regulation of blood coagulation
2000
Vascular bed-specific thrombosis
2007
Thrombosis as an intravascular effector of innate immunity
2012 Standout
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice
2011
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
Gene Expression Profile of Antithrombotic Protein C Defines New Mechanisms Modulating Inflammation and Apoptosis
2001
Effects of human soluble thrombomodulin on experimental glomerulonephritis
2002 StandoutNobel
Extracellular histones are major mediators of death in sepsis
2009 Standout
The immunopathogenesis of sepsis
2002 StandoutNature
The thrombomodulin–protein C system is essential for the maintenance of pregnancy
2003
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Extracellular DNA traps promote thrombosis
2010 Standout
The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation
1989
Modulation of endothelial cell hemostatic properties by tumor necrosis factor.
1986 Standout
The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
2004
Phenotypic Heterogeneity of the Endothelium
2007
Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis
2002 Standout
Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets
1986 StandoutScience
Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis
2010
mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent
2021 StandoutNobel
The role of saliva in tick feeding
2009
Part 9: Post–Cardiac Arrest Care
2010 Standout
Phenotypic Heterogeneity of the Endothelium
2007
The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications
2009
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
2004 StandoutNobel
Coagulation and innate immune responses: can we view them separately?
2009
Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.
1993 Standout
The cytoprotective protein C pathway
2006
The interactions between inflammation and coagulation
2005
Anti-Inflammatory, Antithrombotic, and Neuroprotective Effects of Activated Protein C in a Murine Model of Focal Ischemic Stroke
2001
Tissue Factor Pathway Inhibitor and P-Selectin as Markers of Sepsis-Induced Non-overt Disseminated Intravascular Coagulopathy
2009
A model for thrombin protection against endotoxin
1984
Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow
2005
Chronic Thromboembolic Pulmonary Hypertension
2006 Standout
Engineering the proteolytic specificity of activated protein C improves its pharmacological properties
2003
The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis
2000
Coagulation and inflammation
2001
Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway
2002 Science
Particulate Matter Air Pollution and Cardiovascular Disease
2010 Standout
Thrombin and Phenotypic Modulation of the Endothelium
2003
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Lipopolysaccharide Endotoxins
2002 Standout
Whole blood clot lysis: In vitro modulation by activated protein C
1985
Regulation and functions of the protein C anticoagulant pathway.
1999
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Coagulation inhibitors in inflammation
2005
Natural anticoagulant mechanisms.
1984
Inflammation, sepsis, and coagulation.
1999
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.
1987 Standout
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
Acute inflammation is exacerbated in mice genetically predisposed to a severe protein C deficiency
2006
Flow-mediated endothelial mechanotransduction
1995 Standout
Vessel injury, platelet adherence, and platelet survival.
1983
The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs
1985
Works of Gary Ferrell being referenced
Disruption of the Endothelial Cell Protein C Receptor Gene in Mice Causes Placental Thrombosis and Early Embryonic Lethality
2002
Thrombomodulin Mutations in Atypical Hemolytic–Uremic Syndrome
2009
Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo
2000
Activated Protein C Protects Against Myocardial Ischemia/ Reperfusion Injury via Inhibition of Apoptosis and Inflammation
2009
Identification of the Protein C/Activated Protein C Binding Sites on the Endothelial Cell Protein C Receptor
2001
Distribution of Endothelial Cell Protein C/Activated Protein C Receptor (EPCR) During Mouse Embryo Development
2002
Endothelial cell protein C receptor plays an important role in protein C activation in vivo
2001
Effects of membrane and soluble EPCR on the hemostatic balance and endotoxemia in mice
2006
Extraembryonic expression of EPCR is essential for embryonic viability
2005
Activation of Protein C In Vivo
1982
Patients with severe sepsis vary markedly in their ability to generate activated protein C
2004
Endothelial Protein C Receptor
1999
The Protein C Pathway: New Insights
1997
Human Protein C Receptor Is Present Primarily on Endothelium of Large Blood Vessels
1997
Down-Regulation of Endothelial Expression of Endothelial Cell Protein C Receptor and Thrombomodulin in Coronary Atherosclerosis
2001