Standout Papers
Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Epidermal Growth Factor Receptor Variant III Status Defines Clinically Distinct Subtypes of Glioblastoma
2007
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
2009 StandoutNobel
Breast Cancer Metastasis to the Central Nervous System
2005
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Untangling the ErbB signalling network
2001 Standout
Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas.
2003
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
ERBB receptors and cancer: the complexity of targeted inhibitors
2005 Standout
ErbB-targeted therapeutic approaches in human cancer
2003
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Inflammation and cancer
2002 StandoutNature
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
The discovery of receptor tyrosine kinases: targets for cancer therapy
2004
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
CAR-T cells: the long and winding road to solid tumors
2018
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Epidermal growth factor-related peptides and their receptors in human malignancies
1995 Standout
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
The biology and management of non-small cell lung cancer
2018 StandoutNature
Immunotherapy at Large: The road to personalized cancer vaccines
2013
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression
2004
A phase 3 trial of local chemotherapy with biodegradable carmustine(BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
2003 Standout
Strategies for MMP inhibition in cancer: innovations for the post-trial era
2002
Inhibition of angiogenesis and invasion in malignant gliomas
2007
Enhanced Tumor Eradication by Combining CTLA-4 or PD-1 Blockade With CpG Therapy
2010
Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions
2008
Targeted Molecular Therapy of GBM
2003
Epidemiology of Brain Tumors
2007
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
A comprehensive outlook on intracerebral therapy of malignant gliomas
2010
Modulating T-cell immunity to tumours: new strategies for monitoring T-cell responses
2002
Malignant Gliomas in Adults
2008 Standout
Cancer vaccines: between the idea and the reality
2003
Inhibiting kinases in malignant gliomas
2007
Immunohistochemical Detection of EGFRvIII in High Malignancy Grade Astrocytomas and Evaluation of Prognostic Significance
2004
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Understanding resistance to EGFR inhibitors—impact on future treatment strategies
2010
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
2005 Standout
Primary brain tumours in adults
2012 Standout
An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors
2003
Therapeutic Cancer Vaccines
2013
Identification of human brain tumour initiating cells
2004 StandoutNature
Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth
2013
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
2004 Standout
The cancer genome
2009 StandoutNature
Identification of Novel Tumor-Associated Cell Surface Sialoglycoproteins in Human Glioblastoma Tumors Using Quantitative Proteomics
2014
Recognition of Glioma Stem Cells by Genetically Modified T Cells Targeting EGFRvIII and Development of Adoptive Cell Therapy for Glioma
2012
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells
2011
Structural alterations of the epidermal growth factor receptor gene in human gliomas.
1992
Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2.
2001
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2
2003
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Therapeutic Application of Noncytotoxic Molecular Targeted Therapy in Gliomas: Growth Factor Receptors and Angiogenesis Inhibitors
2008
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Therapeutic Targeting of the Tumor Microenvironment
2021
CTLA-4 blockade in tumor models: an overview of preclinical and translational research.
2013
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients
2012
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Epidermal Growth Factor Receptor Inhibitors in Neuro-oncology: Hopes and Disappointments
2008
Cancer Genome Landscapes
2013 StandoutScience
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors.
1995
Programmable protein circuits in living cells
2018 Science
Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails.
1992
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Neoantigens in cancer immunotherapy
2015 StandoutScience
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
Therapeutic cancer vaccines
2015
Malignant glioma: genetics and biology of a grave matter
2001
Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting
2006
Exploiting the curative potential of adoptive T‐cell therapy for cancer
2013
De novo design of protein logic gates
2020 StandoutScienceNobel
Chemical Glycoproteomics
2016 StandoutNobel
Works of Gary E. Archer being referenced
Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma
2010
Long-term Survival in Glioblastoma with Cytomegalovirus pp65-Targeted Vaccination
2017
Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function
2007 StandoutNobel
An epidermal growth factor receptor variant III–targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme
2009
Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma
2008
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
2015 Nature
The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target
1998
Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system.
1996
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.
1990
Temozolomide as a vaccine adjuvant in GBM
2007
Effect of EGFRvIII-targeted vaccine (CDX-110) on immune response and TTP when given with simultaneous standard and continuous temozolomide in patients with GBM
2008
Poor drug distribution as a possible explanation for the results of the PRECISE trial
2009
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
2002
Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer.
2003
A Novel Inhibitor of Signal Transducers And Activators Of Transcription 3 Activation Is Efficacious Against Established Central Nervous System Melanoma and Inhibits Regulatory T Cells
2008
Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans
2011
Dendritic Cells Pulsed with a Tumor-specific Peptide Induce Long-lasting Immunity and Are Effective against Murine Intracerebral Melanoma
2002
Resistance to Tyrosine Kinase Inhibition by Mutant Epidermal Growth Factor Receptor Variant III Contributes to the Neoplastic Phenotype of Glioblastoma Multiforme
2004
Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumors.
2003
Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts.
1995
Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).
2002
Increased Regulatory T-Cell Fraction Amidst a Diminished CD4 Compartment Explains Cellular Immune Defects in Patients with Malignant Glioma
2006
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors
2000