Standout Papers
Citation Impact
Citing Papers
Mortality and Morbidity in Cushing's Disease over 50 Years in Stoke-on-Trent, UK: Audit and Meta-Analysis of Literature
2010
Persistent epigenetic differences associated with prenatal exposure to famine in humans
2008 Standout
Epigenetic Modification of the Renin-Angiotensin System in the Fetal Programming of Hypertension
2007
Deregulated E2F Activity Induces Hyperplasia and Senescence-Like Features in the Mouse Pituitary Gland
2005
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
A Combined Dexamethasone Desmopressin Test as an Early Marker of Postsurgical Recurrence in Cushing’s Disease
2009
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
The ROR nuclear orphan receptor subfamily: Critical regulators of multiple biological processes
2001
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Long-term remission and recurrence rates in Cushing's disease: predictive factors in a single-centre study
2013
Outcome of Cushing's Disease following Transsphenoidal Surgery in a Single Center over 20 Years
2012
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
Acromegaly
2006 Standout
Cre-mediated somatic site-specific recombination in mice
1997
Mutations in the deubiquitinase gene USP8 cause Cushing's disease
2014
The Orphan Nuclear Receptor SHP Inhibits Agonist-dependent Transcriptional Activity of Estrogen Receptors ERα and ERβ
1999
Sequential hormonal changes in 21 patients with recurrent Cushing's disease after successful pituitary surgery
2011
MANAGEMENT OF ENDOCRINE DISEASE: The burden of Cushing's disease: clinical and health-related quality of life aspects
2012
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Analysis of the human proopiomelanocortin gene promoter in a small cell lung carcinoma cell line reveals an unusual role for E2F transcription factors
1999
Inflammation and metabolic disorders
2006 StandoutNature
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins
2011
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
2001 StandoutNature
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
2006 StandoutNature
Structural architecture of the human long non-coding RNA, steroid receptor RNA activator
2012
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Influence of the Fibroblast Growth Factor Receptor 4 Expression and the G388R Functional Polymorphism on Cushing’s Disease Outcome
2010
Mortality in Cushing's syndrome: A systematic review and meta-analysis
2011
Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors
2000
Cushing's syndrome
2015 Standout
Hypomethylation in the promoter region of POMC gene correlates with ectopic overexpression in thymic carcinoids
2005
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
2007 Nature
Hallmarks of aging: An expanding universe
2023 Standout
Molecular defects in the pathogenesis of pituitary tumours
2003
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance
2007
Phosphorylation of Steroid Receptor Coactivator-1
2000
Ligand-Independent Recruitment of SRC-1 to Estrogen Receptor β through Phosphorylation of Activation Function AF-1
1999
Activation of the Promoter of the Orphan Receptor SHP by Orphan Receptors That Bind DNA as Monomers
1999
Cellular Senescence in Cancer and Aging
2007 Standout
Medical Treatment of Cushing's Disease
2013
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors
2014
The GPR54 Gene as a Regulator of Puberty
2003 Standout
A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis
2000 Standout
Telomeres and telomerase in cancer
2009
GSVA: gene set variation analysis for microarray and RNA-Seq data
2013 Standout
Pros and cons of screening for occult Cushing syndrome
2011
The Ectopic Adrenocorticotropin Syndrome: Clinical Features, Diagnosis, Management, and Long-Term Follow-Up
2006
Engineered telomere degradation models dyskeratosis congenita
2008
Ectopic ACTH syndrome: our experience with 25 cases
2006
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network
2006
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption
1999
DMY is a Y-specific DM-domain gene required for male development in the medaka fish
2002 StandoutNature
Blinded by the Light: The Growing Complexity of p53
2009 Standout
DNA Damage, Aging, and Cancer
2009 Standout
Phosphorylated CREB binds specifically to the nuclear protein CBP
1993 StandoutNature
Large non-coding RNAs: missing links in cancer?
2010
Retinoic acid prevents experimental Cushing syndrome
2001
Transsphenoidal pituitary surgery via the endoscopic technique: results in 35 consecutive patients with Cushing’s disease
2006
Telomere dysfunction and tumour suppression: the senescence connection
2008
Genetics of adrenal tumors associated with Cushing's syndrome: a new classification for bilateral adrenocortical hyperplasias
2007
The Role of the Amygdala in Fear and Anxiety
1992 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
2006
Functional PPAR-γ receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas
2002
The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator
2002 Standout
Outcome of Bilateral Adrenalectomy in Cushing's Syndrome: A Systematic Review
2013
New cell lines from mouse epiblast share defining features with human embryonic stem cells
2007 StandoutNature
Characterisation of ACTH Related Peptides in Ectopic Cushing's Syndrome
2003
Role of shelterin in cancer and aging
2010
Mortality and morbidity in Cushing’s syndrome in New Zealand
2011
Expression of Dmrt1 in the Genital Ridge of Mouse and Chicken Embryos Suggests a Role in Vertebrate Sexual Development
1999
The role of senescent cells in ageing
2014 StandoutNature
Production and Actions of Estrogens
2002 Standout
Role of Ahch in gonadal development and gametogenesis
1998
Cushing's syndrome
2006 Standout
The Hallmarks of Aging
2013 Standout
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
Long-term follow-up results of postoperative radiation therapy for Cushing’s disease
2007
Modulating nuclear receptor function: may the phos be with you
1999
Long-term remission and recurrence rates after first and second transsphenoidal surgery for Cushing's disease: care reality in the Munich Metropolitan Region
2013
Modulation of Glucocorticoid Receptor Function via Phosphorylation
2004
Somatic retrotransposition alters the genetic landscape of the human brain
2011 Nature
Atherosclerosis
2001 Standout
Aberrant G‐protein coupled receptor expression in relation to adrenocortical overfunction
2009
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
Early Morning Cortisol Levels as a Predictor of Remission After Transsphenoidal Surgery for Cushing’s Disease
2006
Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala
1994 StandoutNature
Regulation of Neuropeptide Gene Expression
1990
Surgical Remission of Pituitary Adenomas Confined to the Neurohypophysis in Cushing’s Disease
2006
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
The Molecular Action and Regulation of the Testis-Determining Factors, SRY (Sex-Determining Region on the Y Chromosome) and SOX9 [SRY-Related High-Mobility Group (HMG) Box 9]
2003
Synaptobrevin/vesicle-associated membrane protein (VAMP) of Aplysia californica: structure and proteolysis by tetanus toxin and botulinal neurotoxins type D and F.
1994 StandoutNobel
Orphan Nuclear Receptors: From Gene to Function*
1999
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Authentic Cell-Specific and Developmentally Regulated Expression of Pro-Opiomelanocortin Genomic Fragments in Hypothalamic and Hindbrain Neurons of Transgenic Mice
1998
Gonadotropin-Releasing Hormone Deficiency in the Human (Idiopathic Hypogonadotropic Hypogonadism and Kallmann’s Syndrome): Pathophysiological and Genetic Considerations
1998
Adrenocortical carcinoma: a clinician's update
2011
The coregulator exchange in transcriptional functions of nuclear receptors
2000 Standout
Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin.
1994 StandoutNobel
Efficacy of Adjuvant Radiotherapy of the Tumor Bed on Local Recurrence of Adrenocortical Carcinoma
2006
Physiological and Molecular Basis of Thyroid Hormone Action
2001 Standout
Transsphenoidal surgery for Cushing's disease: a review of success rates, remission predictors, management of failed surgery, and Nelson's Syndrome
2007
Tetanus toxin light chain expression in Sertoli cells of transgenic mice causes alterations of the actin cytoskeleton and disrupts spermatogenesis.
1993
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids
2000 StandoutNobel
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells
2017
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Fission Yeast Pot1-Tpp1 Protects Telomeres and Regulates Telomere Length
2008 Science
Genetic aspects of adrenocortical tumours and hyperplasias
2012
Epidemiology of Cushing’s Syndrome
2010
How Shelterin Protects Mammalian Telomeres
2008 Standout
Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated Nuclear Receptor Ad4BP/SF-1
2009
The Cytogenesis and Pathogenesis of Pituitary Adenomas*
1998
Ectopic and Abnormal Hormone Receptors in Adrenal Cushing’s Syndrome*
2001
Ectopic ACTH syndrome
2007
Nuclear Hormone Receptors and Gene Expression
2001
IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms
2021
Works of Gary D. Hammer being referenced
Molecular Classification and Prognostication of Adrenocortical Tumors by Transcriptome Profiling
2009
Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study
2015
Adjuvant and Definitive Radiotherapy for Adrenocortical Carcinoma
2010
Minireview: Transcriptional Regulation of Adrenocortical Development
2004
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
2007
Transsphenoidal Microsurgery for Cushing’s Disease: Initial Outcome and Long-Term Results
2004
Progression to Adrenocortical Tumorigenesis in Mice and Humans through Insulin-Like Growth Factor 2 and β-Catenin
2012
Adrenocortical cells with stem/progenitor cell properties: Recent advances
2007
Pre-B-Cell Transcription Factor 1 and Steroidogenic Factor 1 Synergistically Regulate Adrenocortical Growth and Steroidogenesis
2006
Genetic p53 Deficiency Partially Rescues the Adrenocortical Dysplasia Phenotype at the Expense of Increased Tumorigenesis
2009
Telomere protection by mammalian Pot1 requires interaction with Tpp1
2007
SF-1, DAX-1, AND ACD: MOLECULAR DETERMINANTS OF ADRENOCORTICAL GROWTH AND STEROIDOGENESIS
2002
Genetic analysis of adrenal absence: agenesis and aplasia
2005
Urogenital and caudal dysgenesis in adrenocortical dysplasia ( acd ) mice is caused by a splicing mutation in a novel telomeric regulator
2004
Ectopic pro-opiomelanocortin syndrome
2002
Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells
2010 Nature
Pituitary-Specific and Hormonally Regulated Gene Expression Directed by the Rat Proopiomelanocortin Promoter in Transgenic Mice
1990
Wilms' Tumor 1 and Dax-1 Modulate the Orphan Nuclear Receptor SF-1 in Sex-Specific Gene Expression
1998
Phosphorylation of the Nuclear Receptor SF-1 Modulates Cofactor Recruitment
1999
Management of patients with adrenal cancer: recommendations of an international consensus conference
2005
Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma
2009
Steroidogenic Factor-1: Its Role in Endocrine Organ Development and Differentiation
1999
Identification of DNA Elements Cooperatively Activating Proopiomelanocortin Gene Expression in the Pituitary Glands of Transgenic Mice
1992
Adrenocorticotropic Hormone-Mediated Signaling Cascades Coordinate a Cyclic Pattern of Steroidogenic Factor 1-Dependent Transcriptional Activation
2005
Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
1993
Dax-1 and Steroid Receptor RNA Activator (SRA) Function as Transcriptional Coactivators for Steroidogenic Factor 1 in Steroidogenesis
2009
SUMOylation Inhibits SF-1 Activity by Reducing CDK7-Mediated Serine 203 Phosphorylation
2008
The effects of naloxone administered into the periaqueductal gray on shock-elicited freezing behavior in the rat
1986
T-Cell Factor 4N (TCF-4N), a Novel Isoform of Mouse TCF-4, Synergizes with β-Catenin To Coactivate C/EBPα and Steroidogenic Factor 1 Transcription Factors
2003
Adrenocortical Carcinoma
2013
Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.
1992
Pituitary corticotroph hyperplasia in rats implanted with a medullary thyroid carcinoma cell line transfected with a corticotropin-releasing hormone complementary deoxyribonucleic acid expression vector.
1992
Preclinical Targeting of the Type I Insulin-Like Growth Factor Receptor in Adrenocortical Carcinoma
2008
Laparoscopic Resection is Inappropriate in Patients with Known or Suspected Adrenocortical Carcinoma
2010