Citation Impact
Citing Papers
NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
2010 StandoutNobel
Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver
2014
Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota
2012 StandoutScience
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
G Protein-coupled Receptor Kinases Phosphorylate LRP6 in the Wnt Pathway
2009 StandoutNobel
microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition
2014
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Caught up in a Wnt storm: Wnt signaling in cancer
2003
Inflammation and cancer
2002 StandoutNature
CD26: a surface protease involved in T-cell activation
1994
Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy
2004
PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs
1999
Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics
2006
WNT and β-catenin signalling: diseases and therapies
2004 Standout
Intestinal tumorigenesis in the Apc1638N mouse treated with aspirin and resistant starch for up to 5 months
1999
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Chemoprevention of Colorectal Cancer
2000
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
2001 Nature
Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared
2002
The chemokine system, and its CCR5 and CXCR4 receptors, as potential targets for personalized therapy in cancer
2013
Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines
2004
Colorectal Cancer and Nonsteroidal Anti-inflammatory Drugs
1997
Lessons from Hereditary Colorectal Cancer
1996 Standout
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.
1997
Long-term treatment with sulindac in familial adenomatous polyposis: Is there an actual efficacy in prevention of rectal cancer?
2000
Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention
2005 Standout
Transcellular Proteolysis Demonstrated by Novel Cell Surface-associated Substrates of Dipeptidyl Peptidase IV (CD26)
2002
COX-2 inhibition and prevention of cancer
2001
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
2015 StandoutNobel
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Sulindac Inhibits Activation of the NF-κB Pathway
1999
The microenvironment of the tumour–host interface
2001 StandoutNature
Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells
1998 Standout
Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
1998
The intestinal epithelial stem cell: the mucosal governor
1997
Hereditary Colorectal Cancer
2003 Standout
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
Aspirin use and potential mechanisms for colorectal cancer prevention.
1997
Non-steroidal anti-inflammatory drugs (NSAIDs) for colorectal cancer prevention
2003
Caffeine promotes anti-tumor immune response during tumor initiation: Involvement of the adenosine A2A receptor
2015
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger
1995
The multifunctional or moonlighting protein CD26/DPPIV
2003
Polyamines and cancer: old molecules, new understanding
2004
Wnt signalling in stem cells and cancer
2005 StandoutNature
Drugging the undruggable RAS: Mission Possible?
2014
Nonsteroidal anti-inflammatory drugs and colorectal cancer: Evolving concepts of their chemopreventive actions
1997
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Roles of PPARs in health and disease
2000 StandoutNature
Molecular Mechanisms of Amyloidosis
2003 Standout
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Prostate cancer invasion and metastasis: insights from mining genomic data
2013
Transcripts encoding a neural membrane CD26 peptidase-like protein are stimulated by synaptic activity
1994
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
2003
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope.
1992 StandoutNobel
Activation of H2O2 by Chiral Confined Brønsted Acids: A Highly Enantioselective Catalytic Sulfoxidation
2012 StandoutNobel
Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression.
1997
Nonsteroidal Anti-Inflammatory Drugs and Cancer Prevention
2000
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
CAAX-box protein, prenylation process and carcinogenesis.
2009
Lymphocyte interactions with extracellular matrix
1991
The 17-residue transmembrane domain of beta-galactoside alpha 2,6-sialyltransferase is sufficient for Golgi retention
1992
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Activation of the Wnt signaling pathway in chronic lymphocytic leukemia
2004
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
The first membrane spanning region of the lamin B receptor is sufficient for sorting to the inner nuclear membrane.
1993 StandoutNobel
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma
1997 StandoutScience
Spermidine in health and disease
2018 StandoutScience
Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy
2017
CYCLOOXYGENASES 1 AND 2
1998 StandoutNobel
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1α (SDF-1α) and SDF-1β are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
1998 StandoutNobel
Cyclooxygenase in biology and disease
1998 Standout
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Applications of Catalytic Asymmetric Sulfide Oxidations to the Syntheses of Biologically Active Sulfoxides
2005
Honokiol: A Review of Its Anticancer Potential and Mechanisms
2019
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 StandoutScience
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways.
2000
The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
1998 Standout
Specific Inhibition of Cyclooxygenase 2 Restores Antitumor Reactivity by Altering the Balance of IL-10 and IL-12 Synthesis
2000
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
2010 StandoutScience
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Apoptosis and APC in colorectal tumorigenesis.
1996
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Works of Gary A. Piazza being referenced
Lysophosphatidic Acid Induction of Transforming Growth Factors α and β: Modulation of Proliferation and Differentiation in Cultured Human Keratinocytes and Mouse Skin
1995
An Undesired Effect of Chemotherapy
2013
Suppression of Wnt/β-catenin signaling inhibits prostate cancer cell proliferation
2008
Sulindac Sulfone Induced Regression of Rectal Polyps in Patients with Familial Adenomatous Polyposis
1999
Effects of sulindac and its metabolites on growth and apoptosis in human mammary epithelial and breast carcinoma cell lines
1998
MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit
2011
Expression of enzymically active rat dipeptidyl peptidase IV in Chinese hamster ovary cells after transfection
1989
Honokiol: A Novel Natural Agent for Cancer Prevention and Therapy
2012 Standout
Inhibition of mammary carcinogenesis in rats by sulfone metabolite of sulindac.
1995
The Role of Cyclic Nucleotide Signaling Pathways in Cancer: Targets for Prevention and Treatment
2014
A Novel Sulindac Derivative Inhibits Lung Adenocarcinoma Cell Growth through Suppression of Akt/mTOR Signaling and Induction of Autophagy
2013
Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.
1995
Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels.
1997
Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G
2009
Sulfone metabolite of sulindac inhibits mammary carcinogenesis.
1997
Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix
1989
Influence of K-ras activation on the survival responses of Caco-2 cells to the chemopreventive agents sulindac and difluoromethylornithine.
2000
Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
2000
Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells.
2003
Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
2000
Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction.
1997
NSAIDs Inhibit Tumorigenesis, but How?
2013
Combinatorial chemoprevention: efficacy of lovostatin and exisulind on the formation and progression of aberrant crypt foci.
2004
A Novel Sulindac Derivative That Does Not Inhibit Cyclooxygenases but Potently Inhibits Colon Tumor Cell Growth and Induces Apoptosis with Antitumor Activity
2009