Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
Extracellular vesicles and particles impact the systemic landscape of cancer
2022
Tumor-associated stromal cells as key contributors to the tumor microenvironment
2016
Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis
2008
The diversity and breadth of cancer cell fatty acid metabolism
2021
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Engineering precision nanoparticles for drug delivery
2020 Standout
Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver
2010
Gallic Acid, an Active Constituent of Grape Seed Extract, Exhibits Anti-proliferative, Pro-apoptotic and Anti-tumorigenic Effects Against Prostate Carcinoma Xenograft Growth in Nude Mice
2009
Apigenin attenuates streptozotocin-induced pancreatic β cell damage by its protective effects on cellular antioxidant defense
2017
Immunosuppressive effect of silibinin in experimental autoimmune encephalomyelitis
2007
Targeting VEGF signalling via the neuropilin co-receptor
2012
Effects of Flavonoids and other Polyphenols on Inflammation
2011 Standout
Silibinin affects tumor cell growth because of reduction of stemness properties and induction of apoptosis in 2D and 3D models of MDA-MB-468
2015
Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity
2022 Standout
Silymarin and its constituents in cardiac preconditioning
2014
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Silibinin modulates TNF‐α and IFN‐γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells
2011
Identification and initial SAR of silybin: An Hsp90 inhibitor
2010
Gallic acid induces G2/M phase cell cycle arrest via regulating 14‐3‐3β release from Cdc25C and Chk2 activation in human bladder transitional carcinoma cells
2010
Cancer metabolism: a therapeutic perspective
2016
The Flavonoid Apigenin Downregulates CDK1 by Directly Targeting Ribosomal Protein S9
2013
Silibinin inhibits hypoxia-inducible factor-1α and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy
2008
Antiangiogenic effects of flavonoids and chalcones
2008
Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status
2016
Prostate cancer chemoprevention by silibinin: Bench to bedside
2006
The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9
2016
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Epidemiology of Prostate Cancer
2019 Standout
Targeting Inflammatory Pathways by Flavonoids for Prevention and Treatment of Cancer
2010
Protective effect of silymarin against cisplatin-induced ototoxicity
2014
The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide
2010
The tumor microenvironment
2020 Standout
Chemopreventive and Anti-Cancer Efficacy of Silibinin Against Growth and Progression of Lung Cancer
2013
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Inhibition of Insulin-like Growth Factor 1 Receptor Signaling Enhanced Silibinin-Induced Activation of Death Receptor and Mitochondrial Apoptotic Pathways in Human Breast Cancer MCF-7 Cells
2008
Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells
2007
Pre-metastatic Niche Formation in Different Organs Induced by Tumor Extracellular Vesicles
2021
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
In vitro and in vivo activity of gallic acid and Toona sinensis leaf extracts against HL-60 human premyelocytic leukemia
2012
Review of natural products with hepatoprotective effects
2014
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Synergistic anti-tumor actions of luteolin and silibinin prevented cell migration and invasion and induced apoptosis in glioblastoma SNB19 cells and glioblastoma stem cells
2015
Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells
2007
Chinese herbal medicine-derived compounds for cancer therapy: A focus on hepatocellular carcinoma
2013
Silymarin induces cell cycle arrest and apoptosis in ovarian cancer cells
2014
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Silymarin selectively protects human renal cells from cisplatin-induced cell death
2011
Broadening horizons: the role of ferroptosis in cancer
2021 Standout
A comprehensive overview of exosomes as drug delivery vehicles — Endogenous nanocarriers for targeted cancer therapy
2014
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
2011 StandoutNobel
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
In vitro antitumor activity of silybin nanosuspension in PC-3 cells
2011
Plasma heme oxygenase-1 is decreased in peripheral artery disease patients
2016
Silibinin Induces Cell Death through Reactive Oxygen Species–Dependent Downregulation of Notch-1/ERK/Akt Signaling in Human Breast Cancer Cells
2014
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
EMT: 2016
2016 Standout
The Origin and Functions of Exosomes in Cancer
2018
Oxidative Stress in Cancer
2020 Standout
A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects
2013 Standout
Therapeutic Efficacy of Silibinin on Human Neuroblastoma Cells: Akt and NF-κB Expressions May Play an Important Role in Silibinin-Induced Response
2012
Reactive oxygen species in cancer
2010 Standout
Multitargeted therapy of cancer by silymarin
2008 Standout
Ac-SDKP suppresses epithelial–mesenchymal transition in A549 cells via HSP27 signaling
2014
Targeting silibinin in the antiproliferative pathway
2010
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Effect of Silibinin in Reducing Inflammatory Pathways in In Vitro and In Vivo Models of Infection-Induced Preterm Birth
2014
Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine
2014
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Metabolic exchanges within tumor microenvironment
2015
Polycyclic Aromatic Hydrocarbons and Digestive Tract Cancers: A Perspective
2011
Signal Transducer and Activator of Transcription‐3, Inflammation, and Cancer
2009 Standout
Silybin and the liver: From basic research to clinical practice
2011
Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice
2009
Chemokines, cytokines and exosomes help tumors to shape inflammatory microenvironment
2016
Silibinin inhibits expression of HIF-1α through suppression of protein translation in prostate cancer cells
2009
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
The Protective Effect of Silibinin Against Mitomycin C–Induced Intrinsic Apoptosis in Human Melanoma A375-S2 Cells
2009
Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells
2012
Silybin-Mediated Inhibition of Notch Signaling Exerts Antitumor Activity in Human Hepatocellular Carcinoma Cells
2013
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
2016 Standout
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Prostate Cancer
2019
Extracellular Vesicles: How Drug and Pathology Interfere With Their Biogenesis and Function
2018
Oncogenic pathways and the electron transport chain: a dangeROS liaison
2019
The history and future of targeting cyclin-dependent kinases in cancer therapy
2015 Standout
Biogenesis and function of extracellular vesicles in cancer
2018
Silybin, a component of sylimarin, exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells
2009
Advances in Hypoxia-Inducible Factor Biology
2017
Regulation of NF-E2-Related Factor 2 Signaling for Cancer Chemoprevention: Antioxidant Coupled with Antiinflammatory
2010
Redox Paradox: A Novel Approach to Therapeutics-Resistant Cancer
2018
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties
2010 Standout
Gallic acid: a versatile antioxidant with promising therapeutic and industrial applications
2015 Standout
Resveratrol as an anti-cancer agent: A review
2016
Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis
2019 Standout
Rapid Label-Free Isolation of Circulating Tumor Cells from Patients’ Peripheral Blood Using Electrically Charged Fe3O4 Nanoparticles
2020
DNA Damage during Reoxygenation Elicits a Chk2-Dependent Checkpoint Response
2006
Milk Thistle Nomenclature: Why It Matters in Cancer Research and Pharmacokinetic Studies
2007
The Therapeutic Potential of Apigenin
2019 Standout
Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth
2015
Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals
2014
The oncolytic virusdl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma
2015
Molecular Mechanisms of the Anti-Obesity and Anti-Diabetic Properties of Flavonoids
2016 Standout
Hepatoprotective effect of silymarin
2014
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
2010
Advances in the Use of Milk Thistle (Silybum marianum)
2007
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas
2015
Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science
2019 Standout
Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
2020
Functional Hydrogels as Wound Dressing to Enhance Wound Healing
2021 Standout
A Novel Role of Silibinin as a Putative Epigenetic Modulator in Human Prostate Carcinoma
2016
Oral Administration of Hydrogel-Embedding Silk Sericin Alleviates Ulcerative Colitis through Wound Healing, Anti-Inflammation, and Anti-Oxidation
2019
Antioxidant properties of the flavonoid fisetin: An updated review of in vivo and in vitro studies
2017
The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo
2013
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Oral Silibinin Inhibits In vivo Human Bladder Tumor Xenograft Growth Involving Down-Regulation of Survivin
2008
Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT
2018
Inhibition of SIRT1 Signaling Sensitizes the Antitumor Activity of Silybin against Human Lung Adenocarcinoma Cells In Vitro and In Vivo
2014
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
MSN Anti‐Cancer Nanomedicines: Chemotherapy Enhancement, Overcoming of Drug Resistance, and Metastasis Inhibition
2013
Chemistry of silybin
2014
The Jujube (Ziziphus Jujuba Mill.) Fruit: A Review of Current Knowledge of Fruit Composition and Health Benefits
2013 Standout
Exosomes as Emerging Pro-Tumorigenic Mediators of the Senescence-Associated Secretory Phenotype
2019
FLAVONOIDS NUTRACEUTICALS IN PREVENTION AND TREATMENT OF CANCER: A REVIEW
2018
Exosomes as drug delivery vehicles for Parkinson's disease therapy
2015 Standout
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression
2017 StandoutNobel
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
New Therapeutic Potentials of Milk Thistle (Silybum marianum)
2013
Toward the Definition of the Mechanism of Action of Silymarin: Activities Related to Cellular Protection From Toxic Damage Induced by Chemotherapy
2007
Comparison of In Vitro and In Vivo Antioxidant Activities of Six Flavonoids with Similar Structures
2020
Silibinin inhibits accumulation of myeloid‐derived suppressor cells and tumor growth of murine breast cancer
2014
Flavonolignans from Aspergillus iizukae, a Fungal Endophyte of Milk Thistle (Silybum marianum)
2014
Clinical Applications ofSilybum marianumin Oncology
2007
Important Flavonoids and Their Role as a Therapeutic Agent
2020 Standout
Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives
2015 Standout
Works of Gagan Deep being referenced
Dietary Feeding of Silibinin Inhibits Prostate Tumor Growth and Progression in Transgenic Adenocarcinoma of the Mouse Prostate Model
2007
Chemopreventive potential of Triphala (a composite Indian drug) on benzo(a)pyrene induced forestomach tumorigenesis in murine tumor model system.
2005
SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin
2014
Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells
2018
The strategies to control prostate cancer by chemoprevention approaches
2014
Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine
2018
Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway
2008
Silymarin and silibinin cause G1 and G2–M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin
2005
Effect of Silibinin on the Growth and Progression of Primary Lung Tumors in Mice
2006
Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies
2016
Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells
2008
Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor Microenvironment
2015
Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer
2010
Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF‐κB, and androgen receptor signaling
2010
A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation
2018
Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship
2013
Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells
2007
Silibinin Exerts Sustained Growth Suppressive Effect against Human Colon Carcinoma SW480 Xenograft by Targeting Multiple Signaling Molecules
2010
Targeting Tumor Microenvironment with Silibinin: Promise and Potential for a Translational Cancer Chemopreventive Strategy
2013
Molecular Mechanisms of Silibinin-Mediated Cancer Chemoprevention with Major Emphasis on Prostate Cancer
2013
Detection of the receptor for advanced glycation endproducts in neuronally-derived exosomes in plasma
2018
Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment
2016
Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling
2012
Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2
2014
Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre‐metastatic niches
2020
Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells
2008
Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells
2011
Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation
2015
Nuclear Factor κB–Dependent Regulation of Angiogenesis, and Metastasis in an In Vivo Model of Thyroid Cancer Is Associated With Secreted Interleukin-8
2014
Stage-Specific Inhibitory Effects and Associated Mechanisms of Silibinin on Tumor Progression and Metastasis in Transgenic Adenocarcinoma of the Mouse Prostate Model
2008
Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts
2015
Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients
2019
CPT1A Supports Castration-Resistant Prostate Cancer in Androgen-Deprived Conditions
2019
Grape seed extract and resveratrol prevent 4‐nitroquinoline 1‐oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses
2013
Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules
2013
Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling
2009
Chemopreventive Efficacy of Silymarin in Skin and Prostate Cancer
2007
Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice
2008
Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft
2009
New combination therapies with cell-cycle agents.
2008