Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Human Neutrophil Granule Cationic Protein CAP37 is a Specific Macrophage Chemotaxin that Shares Homology with Inflammatory Proteinases
1991
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Small-Vessel Vasculitis
1997 Standout
Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils.
1989
Tissue Destruction by Neutrophils
1989 Standout
Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives
1992
Mechanisms of disruption of the articular cartilage surface in inflammation. Neutrophil elastase increases availability of collagen type II epitopes for binding with antibody on the surface of articular cartilage.
1991
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Peptidyl Carbamates as Novel Elastase Inhibitors: Structure-Activity Relationship Studies
1993
Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering
2001
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Disseminated Intravascular Coagulation
1999 Standout
Specificity, stability, and potency of monocyclic .beta.-lactam inhibitors of human leukocyte elastase
1992
Points of control in inflammation
2002 StandoutNature
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Peptide conjugation to an in vitro-selected DNA ligand improves enzyme inhibition.
1995
[9] Hydrophobic chromatography
1974
A model for the association of bovine pancreatic trypsin inhibitor with chymotrypsin and trypsin
1972 StandoutNobel
Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology
2006 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Functional Nucleic Acid Sensors
2009 Standout
The regulatory component of adenylate cyclase. Purification and properties of the turkey erythrocyte protein.
1981 StandoutNobel
Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.
1984 StandoutNobel
Serpin Structure, Mechanism, and Function
2002 Standout
Inactivation of Bronchial Mucous Proteinase Inhibitor by Cigarette Smoke and Phagocyte-Derived Oxidants
1980
Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra
1982 StandoutNobel
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains
1993
X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor.
1986 StandoutNobel
Prevention of degradation of human polymorphonuclear leukocyte proteins by diisopropylfluorophosphate
1980
The Basic Trypsin Inhibitor of Bovine Pancreas
1968
Proteolytic processing of presecretory proteins is required for development of biological activities in pancreatic exocrine proteins.
1983
A STUDY OF THE ACTIVE CENTER OF TRYPSINOGEN BY COMPARATIVE AFFINITY CHROMATOGRAPHY OF TRYPSINOGEN, α‐, β‐, ψ‐TRYPSINS, DIP‐TRYPSIN, CHYMOTRYPSINOGEN, α‐CHYMOTRYPSIN AND ELASTASE
1974
Purification and characterization of the human platelet alpha 2-adrenergic receptor.
1986 StandoutNobel
Lectins: Cell-Agglutinating and Sugar-Specific Proteins
1972 StandoutScience
Structure of bovine pancreatic trypsin inhibitor
1984 StandoutNobel
Specificity and reactivity of human granulocyte elastase and cathepsin G, porcine pancreatic elastase, bovine chymotrypsin and trypsin toward inhibition with sulfonyl flourides
1978
Chemotaxis by polymorphonuclear leukocytes
1978
Structural basis of the activation and action of trypsin
1978 StandoutNobel
Simultaneous isolation of trypsin inhibitor and anti-A phytohemagglutinin from Vicia cracca by means of biospecific adsorption
1970
The Intracellular Serpin Proteinase Inhibitor 6 Is Expressed in Monocytes and Granulocytes and Is a Potent Inhibitor of the Azurophilic Granule Protease, Cathepsin G
1999
Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.
1982
The regulatory component of adenylate cyclase. Purification and properties.
1981 StandoutNobel
Crystallographic refinement and atomic models of two different forms of citrate synthase at 2·7 and 1·7 Å resolution
1982 StandoutNobel
Kinetics and mechanism of human leukocyte elastase inactivation by ynenol lactones
1987
Neutral protease secretion by human monocytes. Effect of surface-bound immune complexes.
1979
Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes.
1983 StandoutNobel
Biochemistry of Natural Proteinase Inhibitors
1974
Preparation of adsorbents for biospecific affinity chromatography
1974
Partial NH2- and cooh-terminal sequence analyses of Eco RI DNA restriction and modification enzymes.
1981 StandoutNobel
The 1.8 Å structure of the complex between chymostatin and Streptomyces griseus protease A
1985
The Basic Trypsin Inhibitor of Bovine Pancreas
1963
Modification of the Single Tryptophan Residue of Staphylococcal Nuclease by a New Mild Oxidizing Agent
1970 StandoutNobel
Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra
1982 StandoutNobel
Dynamics of folded proteins
1977 StandoutNature
Arginyl residues and anion binding sites in proteins
1979
New Peptidic Cysteine Protease Inhibitors Derived from the Electrophilic α-Amino Acid Aziridine-2,3-dicarboxylic Acid
1999
Peptidyl Carbamates as Human Leukocyte Elastase Inhibitors: Design and Synthesis of Desmosine-Like Tetrapeptidyl Carbamate Inhibitors
1993
Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 Å resolution
1982 StandoutNobel
Small-Molecule H-Bond Donors in Asymmetric Catalysis
2007 Standout
Purification of the regulatory component of adenylate cyclase.
1980 StandoutNobel
Detailed Mechanism of Interaction of Bovine β-Trypsin with Soybean Trypsin Inhibitor (Kunitz)
1973
Affinity purification of synthetic peptides.
1976 StandoutNobel
Selective Cleavage and Modification of Peptides and Proteins
1970
The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding
1978 StandoutNobel
Pericellular proteolysis by neutrophils in the presence of proteinase inhibitors: effects of substrate opsonization.
1988
Crystallographic structure studies of an IgG molecule and an Fc fragment
1976 StandoutNatureNobel
Oxidized Redox State of Glutathione in the Endoplasmic Reticulum
1992 StandoutScience
Irreversible inactivation of papain and cathepsin B by epoxidic substrate analogues
1990
Isolation, characterization, and amino-terminal amino acid sequence analysis of human neutrophil cathepsin G from normal donors
1986
Elastase in Tissue Injury
1985
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Immunolocalization of matrix metalloproteinase 3 (stromelysin) in rheumatoid synovioblasts (B cells): correlation with rheumatoid arthritis.
1989
The phylogeny of trypsin-related serine proteases and their zymogens. New methods for the investigation of distant evolutionary relationships
1975
Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis.
1983 StandoutNobel
Metal chelate affinity chromatography, a new approach to protein fractionation
1975 StandoutNature
The 2.5 A X-ray crystal structure of the acid-stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha-chymotrypsin.
1988 StandoutNobel
Severe microvascular injury induced by lysosomal releasates of human polymorphonuclear leukocytes. Increase in vasopermeability, hemorrhage, and microthrombosis due to degradation of subendothelial and perivascular matrices.
1985
Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro.
1990 Standout
Association of anhydrotrypsin with the pancreatic trypsin inhibitors
1974
The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor
1973 Standout
Thrombospondin stimulates motility of human neutrophils.
1990 StandoutNobel
The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.
1988 StandoutNobel
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor
1973 StandoutNobel
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
[72] Human pancreatic secretory trypsin inhibitor
1976
Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor
1987 StandoutNobel
A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates.
1982
Elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces
1978 StandoutNobel
The preparation of anhydro-trypsin and its reactivity with naturally occurring proteinase inhibitors
1972
Ficin and papain inhibitor from chicken egg white
1968
Crystallographic refinement of Japanese quail ovomucoid, a Kazal-type inhibitor, and model building studies of complexes with serine proteases
1982 StandoutNobel
Crystal structure of bovine trypsinogen at 1·8 Å resolution
1977 StandoutNobel
Works of Gad Feinstein being referenced
A rapid method for purification of human granulocyte cationic neutral proteases: purification and characterization of human granulocyte chymotrypsin-like enzyme
1975
Affinity chromatography of biological macromolecules
1971
Purification of trypsin by affinity chromatography on ovomucoid‐sepharose resin
1970
The inhibition of human leucocyte elastase and chymotrypsin-like protease by elastatinal and chymostatin
1976
Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases--a model of joint injury. II. Degradation of isolated bovine nasal cartilage proteoglycan.
1976
Inhibition of Porcine Elastase by Turkey Ovomucoid and Chicken Ovoinhibitor
1971
A rapid method of purification of human granulocyte cationic neutral proteases: purification and further characterization of human granulocyte elastase
1975
Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases--a model of joint injury. I. Penetration of enzyme into rabbit articular cartilage and release of 35SO4-labeled material from the tissue.
1976
Human Pancreatic Proteolytic Enzymes and Protein Inhibitors
1974
Interaction of Inactive Derivatives of Chymotrypsin and Trypsin with Protein Inhibitors
1966
The mechanism of inhibition of trypsin by ovomucoids
1966
Interaction of insoluble protein inhibitors with proteases
1970
Modification of arginines in trypsin inhibitors by 1,2-cyclohexanedione
1968
N-acetyl-(L-Ala)3-p-nitroanilide as a new chromogenic substrate for elastase
1973
Modification of essential carboxylic acid side chains of trypsin
1969
Binding of Proflavine to α-Chymotrypsin and Trypsin and Its Displacement by Avian Ovomucoids*
1967