Citation Impact
Citing Papers
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Systemic Treatment with the Antidiabetic Drug Metformin Selectively Impairs p53-Deficient Tumor Cell Growth
2007
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Prevention of Type 2 Diabetes Mellitus Through Inhibition of the Renin-Angiotensin System
2004
Efficacy of Metformin in Patients with Non-Insulin-Dependent Diabetes Mellitus
1995
Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health
2014
Thiazolidinediones
2004 Standout
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
2004 Standout
Abdominal obesity and metabolic syndrome
2006 StandoutNature
Pioglitazone and cardiovascular risk. A comprehensive meta‐analysis of randomized clinical trials
2008
Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: A randomized, placebo-controlled study
2000
mTOR Signaling in Growth Control and Disease
2012 Standout
Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy
2006
Role of AMP-activated protein kinase in mechanism of metformin action
2001 Standout
Efficacy and safety of rosiglitazone plus metformin in Mexicans with type 2 diabetes
2002
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Insulin and glucosamine infusions increase O-linked N-acetyl-glucosamine in skeletal muscle proteins in vivo
1998
The metabolic syndrome
2010 Standout
Glutamine and cancer: cell biology, physiology, and clinical opportunities
2013
Selective effects of pioglitazone on insulin and androgen abnormalities in normo- and hyperinsulinaemic obese patients with polycystic ovary syndrome
2003
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
2004 Standout
Mitogen-activated protein kinase pathways
1997 Standout
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Uric Acid and Cardiovascular Risk
2008 Standout
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony
2006
Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes
2007 Standout
Effect of Short-Term Glucose Control on Glycemic Thresholds for Epinephrine and Hypoglycemic Symptoms
2001
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
Hypoglycemia in Type 1 Diabetes Mellitus
2004
Nocturnal Hypoglycemia in Type 1 Diabetes: An Assessment of Preventive Bedtime Treatments
2006
The Antihyperglycaemic Effect of Metformin
1999
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia.
1993
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
2016
Efficacy and Metabolic Effects of Metformin and Troglitazone in Type II Diabetes Mellitus
1998
The metabolic syndrome
2005 Standout
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes
2013 Standout
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
RESTORED HYPOGLYCEMIC COUNTERREGULATION IS STABLE IN SUCCESSFUL PANCREAS TRANSPLANT RECIPIENTS FOR UP TO 19 YEARS AFTER TRANSPLANTATION1
2001
Metformin hydrochloride in the treatment of type 2 diabetes mellitus: A clinical review with a focus on dual therapy
2003
IMPROVED GLUCOSE COUNTERREGULATION AND AUTONOMIC SYMPTOMS AFTER INTRAPORTAL ISLET TRANSPLANTS ALONE IN PATIENTS WITH LONG-STANDING TYPE I DIABETES MELLITUS1
1998
Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β‐cell dysfunction
2002
Endocrine Regulation of Energy Metabolism by the Skeleton
2007 Standout
Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
2017
Polycystic Ovary Syndrome
2005 Standout
Effect of Metformin and Rosiglitazone Combination Therapy in Patients With Type 2 Diabetes Mellitus
2000
Obesity as a medical problem
2000 StandoutNature
Metformin reverses fatty liver disease in obese, leptin-deficient mice
2000
Nonhepatic glucose production in humans
2004
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
Glutamine metabolism: Role in acid‐base balance*
2004
AKT/PKB Signaling: Navigating the Network
2017 Standout
Restoration of hypoglycaemia awareness in patients with long-duration insulin-dependent diabetes
1994
Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis
2010 Standout
Dietary Fructose: Implications for Dysregulation of Energy Homeostasis and Lipid/Carbohydrate Metabolism
2005
The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways
2002
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
2014 Standout
The glucose-6 phosphatase gene is expressed in human and rat small intestine: Regulation of expression in fasted and diabetic rats
1999
Roles of PPARs in health and disease
2000 StandoutNature
Mechanisms and Implications of Metabolic Heterogeneity in Cancer
2019
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties
2010 Standout
NOD1 Activators Link Innate Immunity to Insulin Resistance
2011
Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms.
1987
The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome.
1996
Meticulous Prevention of Hypoglycemia Normalizes the Glycemic Thresholds and Magnitude of Most of Neuroendocrine Responses to, Symptoms of, and Cognitive Function During Hypoglycemia in Intensively Treated Patients With Short-Term IDDM
1993
Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation
2005
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Intensive Insulin Therapy Reduces Counterregulatory Hormone Responses to Hypoglycemia in Patients with Type I Diabetes
1985
Attenuation of Counterregulatory Responses to Recurrent Hypoglycemia by Active Thalamic Inhibition
2007
Hypoglycemia-associated autonomic failure in diabetes
2001
Effects of Rosiglitazone and Metformin on Liver Fat Content, Hepatic Insulin Resistance, Insulin Clearance, and Gene Expression in Adipose Tissue in Patients With Type 2 Diabetes
2004
Evaluation and Management of Adult Hypoglycemic Disorders: An Endocrine Society Clinical Practice Guideline
2008
Avoidance of Hypoglycemia Restores Hypoglycemia Awareness by Increasing β-Adrenergic Sensitivity in Type 1 Diabetes
2001
Are Increased Plasma Non-Esterified Fatty Acid Concentrations a Risk Marker for Coronary Heart Disease and other Chronic Diseases?
1996
Dietary Fructose: Implications for Dysregulation of Energy Homeostasis and Lipid/Carbohydrate Metabolism
2005
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis*
1997 Standout
Delayed Recovery of Cognitive Function Following Hypoglycemia in Adults With Type 1 Diabetes
2007
A chemical approach for identifying O -GlcNAc-modified proteins in cells
2003 StandoutNobel
The insulin resistance syndrome in smokers is related to smoking habits.
1994
Uptake and Accumulation of Polystyrene Microplastics in Zebrafish (Danio rerio) and Toxic Effects in Liver
2016 Standout
Spermidine in health and disease
2018 StandoutScience
Pharmacologic Therapy for Type 2 Diabetes Mellitus
1999
Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction
1991
Improving Epinephrine Responses in Hypoglycemia Unawareness With Real-Time Continuous Glucose Monitoring in Adolescents With Type 1 Diabetes
2010
Stimulus specificity of defects in counterregulatory hormone secretion in insulin-dependent diabetes mellitus: effect of glycemic control.
1994
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders
1999
Hypoglycemia-Associated Autonomic Failure in Advanced Type 2 Diabetes
2002
Impact of Bedtime Snack Composition on Prevention of Nocturnal Hypoglycemia in Adults With Type 1 Diabetes Undergoing Intensive Insulin Management Using Lispro Insulin Before Meals
2003
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
2004 StandoutScience
The Barrier of Hypoglycemia in Diabetes
2008
Diabetic Autonomic Neuropathy
2003 Standout
Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society
2013 Standout
Insulin within islets is a physiologic glucagon release inhibitor.
1984
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
2000
Rat Small Intestine Is an Insulin-Sensitive Gluconeogenic Organ
2001
Pathophysiology and Pharmacological Treatment of Insulin Resistance*
2000
Metabolic Effects of Troglitazone Monotherapy in Type 2 Diabetes Mellitus
1998
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
2003 StandoutScience
Defective Glucose Counterregulation after Strict Glycemic Control of Insulin-Dependent Diabetes Mellitus
1987
Cardiovascular safety of sulfonylureas: a meta‐analysis of randomized clinical trials
2013
Mechanism by which metformin reduces glucose production in type 2 diabetes.
2000
Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin
2002 Standout
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
2000 StandoutScience
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
2000 Standout
Works of G. Perriello being referenced
Long-term recovery from unawareness, deficient counterregulation and lack of cognitive dysfunction during hypoglycaemia, following institution of rational, intensive insulin therapy in IDDM
1994
Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans.
1993
Modest decrements in plasma glucose concentration cause early impairment in cognitive function and later activation of glucose counterregulation in the absence of hypoglycemic symptoms in normal man.
1988
ACE-inhibition increases hepatic and extrahepatic sensitivity to insulin in patients with Type 2 (non-insulin-dependent) diabetes mellitus and arterial hypertension
1991
Reversibility of Unawareness of Hypoglycemia in Patients with Insulinomas
1993
Metabolic Effects of Metformin in Non-Insulin-Dependent Diabetes Mellitus
1995
Glutamine: a major gluconeogenic precursor and vehicle for interorgan carbon transport in man.
1995
The dawn phenomenon in Type 1 (insulin-dependent) diabetes mellitus: magnitude, frequency, variability, and dependency on glucose counterregulation and insulin sensitivity
1991
Effects of glucagon on renal and hepatic glutamine gluconeogenesis in normal postabsorptive humans
1998
Role of glutamine in human carbohydrate metabolism in kidney and other tissues
1999
Uptake and release of glucose by the human kidney. Postabsorptive rates and responses to epinephrine.
1995
Comparison of glycaemic control over 1 year with pioglitazone or gliclazide in patients with Type 2 diabetes
2006
Acute effects of lyophilised red wine on total antioxidant capacity in healthy volunteers.
2003
Mechanisms of Insulin Resistance After Insulin-Induced Hypoglycemia in Humans: The Role of Lipolysis
2010
Effects of Long-Term Optimization and Short-Term Deterioration of Glycemic Control on Glucose Counterregulation in Type I Diabetes Mellitus
1984
The Adrenergic Contribution to Glucose Counterregulation in Type I Diabetes Mellitus: Dependency on A-Cell Function and Mediation Through Beta2-Adrenergic Receptors
1983
Estimation of glucose-alanine-lactate-glutamine cycles in postabsorptive humans: role of skeletal muscle
1995
Role of hepatic autoregulation in defense against hypoglycemia in humans.
1985
Mechanisms of glucagon secretion during insulin-induced hypoglycemia in man. Role of the beta cell and arterial hyperinsulinemia.
1984
Glutamine and Alanine Metabolism in NIDDM
1996
Evidence of Increased Systemic Glucose Production and Gluconeogenesis in an Early Stage of NIDDM
1997
Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production
1994
The adrenergic contribution to glucose counterregulation in type I diabetes mellitus. Dependency on A-cell function and mediation through beta 2-adrenergic receptors
1983
Nocturnal Blood Glucose Control in Type I Diabetes Mellitus
1993
Effect of acute and chronic branched-chain amino acids on energy metabolism and muscle performance.
2004
Studies on overnight insulin requirements and metabolic clearance rate of insulin in normal and diabetic man: relevance to the pathogenesis of the dawn phenomenon
1986
Human kidney and liver gluconeogenesis: evidence for organ substrate selectivity
1998
A Reliable and Reproducible Test for Adequate Glucose Counterregulation in Type I Diabetes Mellitus
1984
Adrenergic mechanisms contribute to the late phase of hypoglycemic glucose counterregulation in humans by stimulating lipolysis.
1992
Acute Antihyperglycemic Mechanisms of Metformin in NIDDM: Evidence for Suppression of Lipid Oxidation and Hepatic Glucose Production
1994
Contribution of adrenergic mechanisms to glucose counterregulation in humans
1991
Improved Insulin Action and Glycemic Control After Long Term Angiotensin-Converting Enzyme Inhibition in Subjects with Arterial Hypertension and Type II Diabetes
1993