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Citing Papers
National Institute of Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards
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Experimental Biology of Cerebral Hypoxia-Ischemia: Relation to Perinatal Brain Damage
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Extra‐ and Intracellular pH in the Brain During Ischaemia, Related to Tissue Lactate Content in Normo‐and Hypercapnic rats
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Rapid recovery of rat brain intracellular pH after cardiac arrest and resuscitation
1995
Mitochondrial contributions to tissue damage in stroke
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Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis
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Spreading depression in human neocortical slices
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Microglia: Intrinsic immuneffector cell of the brain
1995
Functional imaging of brain activity in conscious monkeys responding to sexually arousing cues
2001
Diffusion- and perfusion-weighted MR imaging of transient focal cerebral ischaemia in mice
1999
Induction of hypoxia‐inducible factor‐1 (HIF‐1) and its target genes following focal ischaemia in rat brain
1999 StandoutNobel
Microglia: a sensor for pathological events in the CNS
1996 Standout
Regional metabolite profiles in early stages of global ischemia in the gerbil
1986
Damage from oxygen and glucose deprivation in hippocampal slices is prevented by tetrodotoxin, lidocaine and phenytoin without blockade of action potentials
1994
Nitric Oxide and Peroxynitrite in Health and Disease
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Correlation between tissue depolarizations and damage in focal ischemic rat brain1Published on the World Wide Web on 12 July 1999.1
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The Ischemic Penumbra: Identification, Evolution and Treatment Concepts
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The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
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Lactate release from cultured astrocytes and neurons: A comparison
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Local Cerebral Glucose Utilization and Cytoskeletal Proteolysis as Indices of Evolving Focal Ischemic Injury in Core and Penumbra
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Intracellular pH in rat brain in vivo and in brain slices
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Structural and functional features of central nervous system lymphatic vessels
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A Glycine Site Antagonist ZD9379 Reduces Number of Spreading Depressions and Infarct Size in Rats with Permanent Middle Cerebral Artery Occlusion
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Cortical Spreading Depression is Associated with Arachidonic Acid Accumulation and Preservation of Energy Charge
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Cortical spreading depression in the gyrencephalic feline brain studied by magnetic resonance imaging
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Neurovascular regulation in the normal brain and in Alzheimer's disease
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Stroke
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Novel Pharmacologic Strategies in the Treatment of Experimental Traumatic Brain Injury: 1998
1998
Glial and neuronal control of brain blood flow
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Gene-expression profile of the ageing brain in mice
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Glutamate‐Mediated Injury in Focal Cerebral Ischemia: The Excitotoxin Hypothesis Revised
1994
Peri-infarct blood–brain barrier dysfunction facilitates induction of spreading depolarization associated with epileptiform discharges
2012
NADPH Oxidase-Derived Reactive Oxygen Species Mediate the Cerebrovascular Dysfunction Induced by the Amyloid β Peptide
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Increased Formation of Reactive Oxygen Species after Permanent and Reversible Middle Cerebral Artery Occlusion in the Rat
1998
Capillary pericytes regulate cerebral blood flow in health and disease
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Induction of c-Fos, junB, c-Jun, and hsp70 mRNA in Cortex, Thalamus, Basal Ganglia, and Hippocampus following Middle Cerebral Artery Occlusion
1994
Glutamate antagonist MK-801 attenuates incomplete but not complete infarction in thrombotic distal middle cerebral artery occlusion in Wistar rats
1994
Alzheimer's disease
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Calcium metabolism of focal and penumbral tissues in rats subjected to transient middle cerebral artery occlusion
1998
Confocal laser scanning microscopy used to monitor intracellular Ca2+ changes in hippocampal CA 1 neurons during energy deprivation
1998
Oxidants, oxidative stress and the biology of ageing
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Interplay between Cortical Spreading Depolarization and Seizures
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Alzheimer's Disease
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Barbiturate promotes post-ischemic reaggregation of polyribosomes in gerbil hippocampus
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Hydrogen ion compartmentation during and following cerebral ischemia evaluated by 31P NMR spectroscopy
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The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
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Reduction of Infarct Volume by Halothane: Effect on Cerebral Blood Flow or Perifocal Spreading Depression-Like Depolarizations
1997
Endothelin‐1 potently induces Leão’s cortical spreading depression in vivo in the rat
2002
Stimulus‐Transcription Coupling in Focal Cerebral Ischemia
1994
Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex
2011
Rat brain tumor models in experimental neuro-oncology:The 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 Gliomas
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The P2Y12 receptor regulates microglial activation by extracellular nucleotides
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Hippocampal slices: glutamate overflow and cellular damage from ischemia are reduced by sodium-channel blockade
1995
The role of spreading depression in focal ischemia evaluated bv dffusion mapping
1996
Comparative analysis of brain protection by N-methyl-D-aspartate receptor antagonists after transient focal ischemia in cats
1997
Acidosis and ischemic brain damage
1988
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
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The heterogeneous temporal evolution of focal ischemic neuronal damage in the rat
1993
BI-1 Regulates an Apoptosis Pathway Linked to Endoplasmic Reticulum Stress
2004 StandoutNobel
Early and rapid de novo synthesis of Alzheimer βA4‐Amyloid precursor protein (APP) in activated microglia
1993
CNS energy metabolism as related to function
2000
Spreading depression: a review of the clinical relevance
2001
Treatment of Traumatic Brain Injury with Moderate Hypothermia
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Nitric oxide synthase inhibition does not affect somatosensory evoked potentials in the rat
1996
Suppressed Neuronal Activity and Concurrent Arteriolar Vasoconstriction May Explain Negative Blood Oxygenation Level-Dependent Signal
2007
Down-regulation of complement receptor 3 and major histocompatibility complex I and II antigen-like immunoreactivity accompanies ramification in isolated rat microglia
2002
Infarct tolerance against temporary focal ischemia following spreading depression in rat brain
1998
Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke
1997
Protective Effect of Hypothermia on Hippocampal Injury After 30 Minutes of Forebrain Ischemia in Rats Is Mediated by Postischemic Recovery of Protein Synthesis
1993
Dynamic changes in local cerebral glucose utilization following cerebral concussion in rats: evidence of a hyper- and subsequent hypometabolic state
1991
Viability thresholds and the penumbra of focal ischemia
1994
Adrenomedullin Gene Delivery Protects Against Cerebral Ischemic Injury by Promoting Astrocyte Migration and Survival
2004
Factors Influencing the Frequency of Fluorescence Transients as Markers of Peri-Infarct Depolarizations in Focal Cerebral Ischemia
2000
Threshold of calcium disturbances after focal cerebral ischemia in rats. Implications of the window of therapeutic opportunity.
1993
HIF-1: mediator of physiological and pathophysiological responses to hypoxia
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Tumor Metabolism of Lactate: The Influence and Therapeutic Potential for MCT and CD147 Regulation
2009
Biologic Correlates of 18Fluorodeoxyglucose Uptake in Human Breast Cancer Measured by Positron Emission Tomography
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Induction of Spreading Depression in the Ischemic Hemisphere following Experimental Middle Cerebral Artery Occlusion: Effect on Infarct Morphology
1996
A Reproducible Model of Middle Cerebral Artery Occlusion in Mice: Hemodynamic, Biochemical, and Magnetic Resonance Imaging
1998
Cortical Negative DC Deflections following Middle Cerebral Artery Occlusion and KCl-Induced Spreading Depression: Effect on Blood Flow, Tissue Oxygenation, and Electroencephalogram
1994
Cortical Spreading Depression Protects against Subsequent Focal Cerebral Ischemia in Rats
1996
Ischemic Stroke and Incomplete Infarction
1996
Ischemic Delayed Neuronal Death
1995
INFLAMMATION AND ALZHEIMERS DISEASE
2000
Progressive Derangement of Periinfarct Viable Tissue in Ischemic Stroke
1992
Human specific loss of olfactory receptor genes
2003 StandoutNobel
Cerebral energetics and spiking frequency: The neurophysiological basis of fMRI
2002
Intracellular and extracellular changes of [Ca2+] in hypoxia and ischemia in rat brain in vivo.
1990
Multiple-Radionuclide Autoradiography in Evaluation of Cerebral Function
1984
Induction of Heme Oxygenase Protein Protects Neurons in Cortex and Striatum, But Not in Hippocampus, against Transient Forebrain Ischemia
1998
Effect of Photic Stimulation on Human Visual Cortex Lactate and Phosphates Using 1H and 31P Magnetic Resonance Spectroscopy
1992
Global cerebral ischemia and intracellular pH during hyperglycemia and hypoglycemia in cats.
1988
Simultaneous Measurement of Local Glucose Utilization and Blood Flow in the Rat Brain: An Autoradiographic Method Using Two Tracers Labeled with Carbon-14
1983
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
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Photothrombotic Infarction Triggers Multiple Episodes of Cortical Spreading Depression in Distant Brain Regions
1994
Dynamic Changes in Cortical NADH Fluorescence and Direct Current Potential in Rat Focal Ischemia: Relationship between Propagation of Recurrent Depolarization and Growth of the Ischemic Core
2002
Relationship between plasma glucose, brain lactate, and intracellular pH during cerebral ischemia in gerbils.
1990
Mechanisms of migraine aura revealed by functional MRI in human visual cortex
2001 Standout
Local and Propagated Vascular Responses Evoked by Focal Synaptic Activity in Cerebellar Cortex
1997
Attenuated Neurotransmitter Release and Spreading Depression-Like Depolarizations after Focal Ischemia in Mutant Mice with Disrupted Type I Nitric Oxide Synthase Gene
1998
A Semiautomated Method for Measuring Brain Infarct Volume
1990 Standout
Regional cerebral blood flow during cortical spreading depression in rat brain: increased reactive hyperperfusion in low-flow states
1987
Mild acidosis delays hypoxic spreading depression and improves neuronal recovery in hippocampal slices
1994
Persisting Depletion of Brain Glucose following Cortical Spreading Depression, despite Apparent Hyperaemia: Evidence for Risk of an Adverse Effect of Leão's Spreading Depression
2008
Extracellular Potassium in a Neocortical Core Area After Transient Focal Ischemia
1997
Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.
1994 Standout
Extracellular pH in the Brain during Ischemia: Relationship to the Severity of Lactic Acidosis
1991
Transient Middle Cerebral Artery Occlusion by Intraluminal Suture: I. Three-Dimensional Autoradiographic Image-Analysis of Local Cerebral Glucose Metabolism—Blood Flow Interrelationships during Ischemia and Early Recirculation
1997
Characterization of Cortical Depolarizations Evoked in Focal Cerebral Ischemia
1993
Brain ischemia and reperfusion: molecular mechanisms of neuronal injury
2000
Conditions for pharmacologic evaluation in the gerbil model of forebrain ischemia.
1989
Potassium-Induced Cortical Spreading Depressions during Focal Cerebral Ischemia in Rats: Contribution to Lesion Growth Assessed by Diffusion-Weighted NMR and Biochemical Imaging
1996
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters
2008 StandoutNobel
Three-Dimensional Image Analysis of Brain Glucose Metabolism-Blood Flow Uncoupling and its Electrophysiological Correlates in the Acute Ischemic Penumbra following Middle Cerebral Artery Occlusion
1995
Lamotrigine Protects Hippocampal CA1 Neurons From Ischemic Damage After Cardiac Arrest
1997
Transient Middle Cerebral Artery Occlusion by Intraluminal Suture: II. Neurological Deficits, and Pixel-Based Correlation of Histopathology with Local Blood Flow and Glucose Utilization
1997
Prevention of Postischemic Hyperthermia Prevents Ischemic Injury of CA1 Neurons in Gerbils
1990
Mild hypothermia ameliorates ubiquitin synthesis and prevents delayed neuronal death in the gerbil hippocampus.
1991
Ischemic Cell Death in Brain Neurons
1999 Standout
Functional Activation of Cerebral Blood Flow and Metabolism before and after Global Ischemia of Rat Brain
1988
Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats.
1986 Standout
The Chemistry of Neutron Capture Therapy
1998 Standout
Protection from Oxidative Stress–Induced Apoptosis in Cortical Neuronal Cultures by Iron Chelators Is Associated with Enhanced DNA Binding of Hypoxia-Inducible Factor-1 and ATF-1/CREB and Increased Expression of Glycolytic Enzymes, p21waf1/cip1, and Erythropoietin
1999 StandoutNobel
Prevention of Periinfarct Direct Current Shifts with Glutamate Antagonist NBQX following Occlusion of the Middle Cerebral Artery in the Rat
1994
Local Uncoupling of the Cerebrovascular and Metabolic Responses to Somatosensory Stimulation after Neuronal Nitric Oxide Synthase Inhibition
1997
Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury
2000 Standout
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Effect of 5-minute ischemia on regional pH and energy state of the gerbil brain: relation to selective vulnerability of the hippocampus.
1987
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice
2002 StandoutNobel
Delayed Secondary Phase of Peri-Infarct Depolarizations after Focal Cerebral Ischemia: Relation to Infarct Growth and Neuroprotection
2003
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Mechanisms of Spreading Depression and Hypoxic Spreading Depression-Like Depolarization
2001
Effect of calcium antagonists on postischemic protein biosynthesis in gerbil brain.
1992
Regional Cerebral Metabolites, Blood Flow, Plasma Volume, and Mean Transit Time in Total Cerebral Ischemia in the Rat
1991
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Dynamic Penumbra Demonstrated by Sequential Multitracer PET after Middle Cerebral Artery Occlusion in Cats
1994
Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype
2007
Spreading depolarizations occur in human ischemic stroke with high incidence
2008
Neuronal injury in the infarct border: a neuropathological study in the rat
1987
Hyperglycemic versus Normoglycemic Stroke: Topography of Brain Metabolites, Intracellular pH, and Infarct Size
1992
Reversible middle cerebral artery occlusion without craniectomy in rats.
1989 Standout
Works of G. Mies being referenced
Expression of c-fos, junB, c-jun, MKP-1 AND hsp72 following traumatic neocortical lesions in rats—relation to spreading depression
1999
Effect of alpha‐chloralose, halothane, pentobarbital and nitrous oxide anesthesia on metabolic coupling in somatosensory cortex of rat
1992
Expression of redox factor-1, p53-activated gene 608 and caspase-3 messenger RNAs following repeated unilateral common carotid artery occlusion in gerbils—Relationship to delayed cell injury and secondary failure of energy state
2001
Microglial Reaction in the Rat Cerebral Cortex Induced by Cortical Spreading Depression
1993
Regional profile of polyamines in reversible cerebral ischemia of Mongolian gerbils
1987
MK-801, a glutamate antagonist, lowers flow threshold for inhibition of protein synthesis after middle cerebral artery occlusion of rat
1993
Relationship between metabolic dysfunctions, gene responses and delayed cell death after mild focal cerebral ischemia in mice
2001
Threshold relationship between cerebral blood flow, glucose utilization, and energy metabolites during development of stroke in gerbils
1992
Ischemic threshold of brain protein synthesis after unilateral carotid artery occlusion in gerbils.
1989
Low dose of barbiturates for prevention of hippocampal lesions after brief ischemic episodes
1985
Lactate and pH in the Brain: Association and Dissociation in Different Pathophysiological States
1987
Regional Quantitative Determination of Brain Glucose in Tissue Sections: A Bioluminescent Approach
1985
Triple-Tracer Autoradiography of Cerebral Blood Flow, Glucose Utilization, and Protein Synthesis in Rat Brain
1986
Multiparametric Imaging of Blood Flow and Metabolism after Middle Cerebral Artery Occlusion in Cats
1985
A Double Tracer Autoradiographic Technique for Simultaneous Measurement of Cerebral Blood Flow and Cerebral Metabolism in Rats
1981
Flow and neuronal density in tissue surrounding chronic infarction.
1983
Repeated Negative DC Deflections in Rat Cortex following Middle Cerebral Artery Occlusion are Abolished by MK-801: Effect on Volume of Ischemic Injury
1992
Regional changes of blood flow, glucose, and ATP content determined on brain sections during a single passage of spreading depression in rat brain cortex
1984
Regional metabolism of experimental brain tumors
1986
Neuronal injury following permanent middle cerebral artery occlusion in cats
1983
Regional cerebral blood flow, glucose metabolism, protein synthesis, serum protein extravasation, and content of biochemical substrates in stroke-prone spontaneously hypertensive rats.
1985
Cerebral Blood Flow, Glucose Utilization, Regional Glucose, and ATP Content during the Maturation Period of Delayed Ischemic Injury in Gerbil Brain
1990
Simultaneous measurement of blood flow and glucose metabolism by autoradiographic techniques.
1981
Regional changes in tissue pH and glucose content during cortical spreading depression in rat brain
1985
Ischemic Thresholds of Cerebral Protein Synthesis and Energy State following Middle Cerebral Artery Occlusion in Rat
1991