Standout Papers
Citation Impact
Citing Papers
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da
1988 StandoutNobel
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Chemistry and biology of prions
1992
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
1993
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
2007
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
The chemistry of scrapie infection: implications of the ‘ice 9’ metaphor
1995
Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob Disease
1994
Scrapie prions: a three-dimensional model of an infectious fragment
1996
A 'unified theory' of prion propagation
1991 Nature
Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome
1989 StandoutNatureNobel
Asparagine-linked glycosylation of the scrapie and cellular prion proteins
1989
Evidence for a secretory form of the cellular prion protein
1987 StandoutNobel
Structural Clues to Prion Replication
1994 StandoutScienceNobel
Human prion diseases
1994 StandoutNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
Transmissible and non-transmissible amyloidoses: autocatalytic post-translational conversion of host precursor proteins to β-pleated sheet configurations
1988 Nobel
Search for a Scrapie‐Specific Nucleic Acid: A Progress Report
2007 Nobel
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1997 StandoutNatureNobel
Structural Basis for Thrombin Activation of a Protease-Activated Receptor
2003
A β-Arrestin-dependent Scaffold Is Associated with Prolonged MAPK Activation in Pseudopodia during Protease-activated Receptor-2-induced Chemotaxis
2003
Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein
1990 StandoutNatureNobel
The exceptionally small size of the scrapie agent
1966
Scrapie prions aggregate to form amyloid-like birefringent rods
1983 StandoutNobel
Replication of the Factor in Scrapie Material That Causes a Decrease in Polymorphonuclear Neutrophils
1973
Scrapie-Induced Changes in the Percentage of Polymorphonuclear Neutrophils in Mouse Peripheral Blood
1972
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
1997 StandoutNobel
Sedimentation characteristics of the scrapie agent from murine spleen and brain
1978 StandoutNobel
Scrapie PrP 27-30 is a sialoglycoprotein
1985
Aggregations of 35-Nanometer Particles Associated with Neuronal Cytopathic Changes in Natural Scrapie
1971 Science
Sedimentation properties of the scrapie agent.
1977
Detection of the Scrapie Agent in Tissues of Normal Mice
1968 Nature
No Mouse PMN Leukocyte Depression after Inoculation with Brain Tissue from Multiple Sclerosis or Spongiform Encephalopathies
1974 StandoutNatureNobel
Properties of scrapie prion protein liposomes.
1988 StandoutNobel
Comparison of Scrapie and Transmissible Mink Encephalopathy in Hamsters. II. Clinical Signs, Pathology, and Pathogenesis
1975
Search for Infectious Etiology in Chronic and Subacute Degenerative Diseases of the Central Nervous System
1967
Molecular characteristics of the major scrapie prion protein
1984 StandoutNobel
Purification and structural studies of a major scrapie prion protein
1984 StandoutNobel
Purification of the Scrapie Agent by Density Gradient Centrifugation
1984
Evidence for an essential DNA component in the Scrapie agent
1978 Nature
Viroids and prions.
1982
SYNTHESIS OF NASCENT PROTEIN BY RIBOSOMES IN ESCHERICHIA COLI
1959
Partial purification of the scrapie agent from mouse brain by pressure disruption and zonal centrifugation in sucrose-sodium chloride gradients
1976 StandoutNobel
Biohazards of Investigations on the Transmissible Spongiform Encephalopathies
1980 StandoutNobel
Ruthenium red and lanthanum nitrate a possible tracer and negative stain for scrapie ?particles??
1974
Electrophoretic properties of the scrapie agent in agarose gels.
1980 StandoutNobel
DISTRIBUTION OF NEWLY SYNTHESIZED AMYLASE IN MICROSOMAL SUBFRACTIONS OF GUINEA PIG PANCREAS
1966 StandoutNobel
Prions are novel infectious pathogens causing scrapie and creutzfeldt—Jakob disease
1986 StandoutNobel
Properties of the scrapie agent-endomembrane complex from hamster brain
1976
Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity
1996 StandoutNobel
An Unstable Intermediate Carrying Information from Genes to Ribosomes for Protein Synthesis
1961 StandoutNatureNobel
Characteristics of a Short Incubation Model of Scrapie in the Golden Hamster
1977
Scrapie and Cellular Prion Proteins Share Polypeptide Epitopes
1986
Evidence of mitochondrial involvement in scrapie infection
1989
Partial purification and evidence for multiple molecular forms of the scrapie agent
1978 StandoutNobel
Scrapie in Immunologically Deficient Mice
1971 Nature
Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]
1987 StandoutNobel
Susceptibility of Scrapie Agent to Ionizing Radiation
1969 Nature
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
Identification of a Protein That Purifies with the Scrapie Prion
1982 StandoutScienceNobel
Membrane-free scrapie activity
1978
Course of Experimental Scrapie Virus Infection in the Goat
1974
Central Dogma of Molecular Biology
1970 StandoutNature
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review.
1972 StandoutNobel
AMINO ACID INCORPORATION INTO PROTEINS BY ESCHERICHIA COLI RIBOSOMES
1960
RESISTANCE OF THE SCRAPIE AGENT TO INACTIVATION BY PSORALENS
1983
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
The Yin and Yang of Oxidation in the Development of the Fatty Streak
1996 Standout
Unconventional Viruses and the Origin and Disappearance of Kuru
1977 ScienceNobel
An electron microscopic study of natural scrapie sheep brain: Further observations on virus-like particles and paramyxovirus-like tubules
1974
Prions
1998 StandoutNobel
Reversible Chemical Modification of the Scrapie Agent
1981 StandoutScienceNobel
Physical properties of the Creutzfeldt-Jakob disease agent
1989
A protease-resistant protein is a structural component of the Scrapie prion
1983 StandoutNobel
Gel electrophoresis and glass permeation chromatography of the hamster scrapie agent after enzymatic digestion and detergent extraction
1980 StandoutNobel
Unusual Topogenic Sequence Directs Prion Protein Biogenesis
1990 StandoutScienceNobel
Thiocyanate and hydroxyl ions inactivate the scrapie agent.
1981 StandoutNobel
Experimental scrapie in mice: Ultrastructural observations
1978 StandoutNobel
Altered plasma membranes in experimental scrapie
1971
Scrapie in Mice. The Stability of the Agent to Various Suspending Media, pH and Solvent Extraction
1965
Separation and properties of cellular and scrapie prion proteins.
1986 StandoutNobel
Towards Purification of the Scrapie Agent
1983
Scrapie infectious agent is virus-like in size and susceptibility to inactivation
1984 Nature
Is the scrapie agent a virus?
1976 Nature
Inability to Transmit Scrapie by Transfection of Mouse Embryo Cells in vitro
1982
THE INFECTIVE PROCESS IN SCRAPIE
1968
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Experimental Scrapie in the Mouse: Electrophoretic and Sedimentation Properties of the Partially Purified Agent
1980 StandoutNobel
A comparison of the biochemical changes induced in mouse brain by cuprizone toxicity and by scrapie infection
1974
Failure to demonstrate a Relationship between Scrapie and Production of Interferon in Mice
1968 Nature
Prions: Novel Infectious Pathogens
1984 StandoutNobel
Scrapie agent contains a hydrophobic protein.
1981
Conservation of infectivity in purified fibrillary extracts of scrapie-infected hamster brain after sequential enzymatic digestion or polyacrylamide gel electrophoresis.
1990 Nobel
Cloning of a Gene Whose Expression Is Increased in Scrapie and in Senile Plaques in Human Brain
1985 Science
Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]
1987
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Unstable Ribonucleic Acid Revealed by Pulse Labelling of Escherichia Coli
1961 StandoutNatureNobel
Is the Scrapie Agent a Viroid?
1972
STUDIES ON DNA FROM NORMAL AND SCRAPIE‐AFFECTED MOUSE BRAIN
1972
Prion liposomes
1990 StandoutNobel
A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7
1969
Antibodies to a scrapie prion protein
1984 StandoutNatureNobel
Purified prion proteins and scrapie infectivity copartition into liposomes.
1987 StandoutNobel
Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes
1979
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
1990 StandoutScienceNobel
Experimental Subacute Spongiform Virus Encephalopathies in Primates and Other Laboratory Animals
1973 StandoutScienceNobel
Works of G. D. Hunter being referenced
Absence of Eclipse Phase in Scrapie Mice
1972
Nature of the Scrapie Agent
1967 Nature
Glycoprotein biosynthesis in normal and scrapie-affected mouse brain
1973
The Intracellular Location of the Agent of Mouse Scrapie
1964
The biosynthesis of cholesterol from acetate
1953 StandoutNobel
Scrapie : A modified membrane hypothesis
1968
Changes in a Protein-Nucleic Acid Complex from Synaptic Plasma Membrane of Scrapie-Infected Mouse Brain
1976
Proteinase-activated Receptors
2006
Later Stages of Protein Synthesis and the Role of Phospholipids in the Process
1961 Nature
Studies on the Heat Stability and Chromatographic Behaviour of the Scrapie Agent
1964
Attempts to release the scrapie agent from tissue debris
1967
An experimental examination of the scrapie agent in cell membrane mixtures
1971
DNA Synthesis in Scrapie-Affected Mouse Brain
1967
DISTRIBUTION AND ACTIVATION OF LYSOSOMAL ENZYME ACTIVITIES IN SUBCELLULAR COMPONENTS OF NORMAL AND SCRAPIE‐AFFECTED MOUSE BRAIN
1966
An experimental examination of the scrapie agent in cell membrane mixtures
1971
Search for Scrapie-specific RNA and Attempts to Detect an Infectious DNA or RNA
1976
Further Experiments on the Comparative Potency of Tissue Extracts from Mice Infected with Scrapie
1964
Scrapie: A Prototype Slow Infection
1972
Intermediate reactions in protein synthesis by the isolated cytoplasmic-membrane fraction of Bacillus megaterium
1959
An experimental examination of the scrapie agent in cell membrane mixtures
1971
Further studies of the infectivity and stability of extracts and homogenates derived from scrapie affected mouse brains
1969
Observations on the Comparative Infectivity of Cellular Fractions Derived from Homogenates of Mouse-scrapie Brain
1963
The site of protein synthesis in Bacillus megaterium
1958
The size and intracellular location of the scrapie agent
1969