Citation Impact
Citing Papers
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Leptin therapy in insulin-deficient type I diabetes
2010
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Molecular and Cellular Aspects of Thiol–Disulfide Exchange
1990
Regulation of classic and alternative bile acid synthesis in hypercholesterolemic rabbits: effects of cholesterol feeding and bile acid depletion
1998
Analysis of gene expression during adipogenesis in 3T3‐F442A preadipocytes: Insulin and dexamethasone control
1990
PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo
1995 Standout
Role of AMP-activated protein kinase in mechanism of metformin action
2001 Standout
Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
2002
REGULATION OF BILE ACID BIOSYNTHESIS
1999
The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor
1997 StandoutNobel
Purification and characterization of the AMP‐activated protein kinase
1989
Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα
1998
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
2004 Standout
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis in Syrian hamster C100 cells by mevinolin, 25-hydroxycholesterol, and mevalonate: The role of posttranscriptional control
1992
Cellular Cholesterol Efflux Mediated by Cyclodextrins
1995 Standout
Degradation of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Endoplasmic Reticulum Membranes Is Accelerated as a Result of Increased Susceptibility to Proteolysis
1996 StandoutNobel
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Defective Cholesterol Biosynthesis Associated with the Smith-Lemli-Opitz Syndrome
1994
Thyroid Hormone Receptor β-Deficient Mice Show Complete Loss of the Normal Cholesterol 7α-Hydroxylase (CYP7A) Response to Thyroid Hormone but Display Enhanced Resistance to Dietary Cholesterol
2000
Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver
1999
Tissue distribution of the AMP‐activated protein kinase, and lack of activation by cyclic‐AMP‐dependent protein kinase, studied using a specific and sensitive peptide assay
1989
Differential Regulation of Rat and HumanCYP7A1by the Nuclear Oxysterol Receptor Liver X Receptor-α
2003
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Metabolic Delivery of Ketone Groups to Sialic Acid Residues
1998 StandoutNobel
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
2007 Standout
Regulation of the mevalonate pathway
1990 StandoutNature
Identification and Characterization of a Mouse Oxysterol 7α-Hydroxylase cDNA
1997
Inositol 1,4,5-Trisphosphate receptor causes formation of ER cisternal stacks in transfected fibroblasts and in cerebellar purkinje cells
1994 StandoutNobel
Animal safety and toxicology of simvastatin and related hydroxy-methylglutaryl-coenzyme a reductase inhibitors
1989
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
The Gap Junction Communication Channel
1996 Standout
Fibrate induction of the adrenoleukodystrophy‐related gene (ABCD2)
2001
Lipids and thyroid hormones
1988
Bile acid biosynthesis
1992
AMPK: a nutrient and energy sensor that maintains energy homeostasis
2012 Standout
Effect of thyroid hormone on hepatic cholesterol 7α hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats
1990
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
Regulation of bile acid synthesis
1998
Oxidative damage and mitochondrial decay in aging.
1994 Standout
Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis
1986 StandoutScience
Christian Raetz: Scientist and Friend Extraordinaire
2013 StandoutNobel
The Farnesoid X Receptor
2005
Hypolipidemic effects of β‐cyclodextrin in the hamster and in the genetically hypercholesterolemic rico rat
1993
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Chemical Glycobiology
2001 StandoutScienceNobel
Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling
1998 StandoutScience
Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro.
1994
The membrane domain of 3-hydroxy-3-methylglutaryl-coenzyme A reductase confers endoplasmic reticulum localization and sterol-regulated degradation onto beta-galactosidase.
1988
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Differential regulation of multiple gap junction transcripts and proteins during rat liver regeneration.
1993
Cyclodextrin Drug Carrier Systems
1998 Standout
Oxysterols: Modulators of Cholesterol Metabolism and Other Processes
2000
Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice
1993
Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver.
1990
Expression and purification of human cholesterol 7 alpha-hydroxylase in Escherichia coli.
1994
Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver.
1995
A Receptor-Mediated Pathway for Cholesterol Homeostasis
1986 StandoutScienceNobel
Understanding Adipocyte Differentiation
1998 Standout
Purification, molecular cloning, and expression of the mammalian sigma1-binding site.
1996
Defective forebrain development in mice lacking gp330/megalin.
1996 Standout
Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
2002
Investigating Cellular Metabolism of Synthetic Azidosugars with the Staudinger Ligation
2002 StandoutNobel
Antioxidant-induced changes of the AP-1 transcription complex are paralleled by a selective suppression of human papillomavirus transcription
1997 StandoutNobel
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
1999 StandoutScience
mRNA stability in mammalian cells
1995
Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors
1998 Standout
Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo
1999
Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum
1992
Genetic and Biochemical Evaluation of Eucaryotic Membrane Protein Topology: Multiple Transmembrane Domains of Saccharomyces cerevisiae 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase
1990 StandoutNobel
Isoprenoid Biosynthesis in Plants: Carbon Partitioning Within the Cytoplasmic Pathway
1999
The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers
2005 Standout
INHIBITORS OF THE BIOSYNTHESIS AND PROCESSING OF N-LINKED OLIGOSACCHARIDE CHAINS
1987
Oxidized Redox State of Glutathione in the Endoplasmic Reticulum
1992 StandoutScience
EcoK selection vectors for shotgun cloning into M13 and deletion mutagenesls
1985 StandoutNobel
Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme
1985 StandoutNobel
Radiation target analysis of glycoproteins
1986
Partial deletion of membrane-bound domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase eliminates sterol-enhanced degradation and prevents formation of crystalloid endoplasmic reticulum.
1987
The regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase requires a short-lived protein and occurs in the endoplasmic reticulum.
1990
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
2003 StandoutScience
Identification of a Nuclear Receptor for Bile Acids
1999 StandoutScience
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
Prion liposomes
1990 StandoutNobel
Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductase.
1990 StandoutNobel
Works of G C Ness being referenced
Increasing Hepatic Cholesterol 7α–Hydroxylase Reduces Plasma Cholesterol Concentrations in Normocholesterolemic and Hypercholesterolemic Rabbits
1996
Identification and Regulation of Rat Squalene Synthetase mRNA
1993
Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits.
1995
A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.
1990
Thyroid Hormone Rapidly Induces Hepatic LDL Receptor mRNA Levels in Hypophysectomized Rats
1994
Effect of Squalene Synthase Inhibition on the Expression of Hepatic Cholesterol Biosynthetic-Enzymes, LDL Receptor, and Cholesterol 7α Hydroxylase
1994
Studies on the regulation of glycoprotein biosynthesis. An investigation of the rate-limiting steps of dolichyl phosphate biosynthesis.
1979
Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels
1991
Transcriptional and posttranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase by thyroid hormones.
1988
Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers.
1984
Radiation inactivation analysis of rat liver microsomal glucose-6-phosphatase
1989
Purification of cholesterol 7 alpha-hydroxylase from human and rat liver and production of inhibiting polyclonal antibodies.
1990
Characteristics of magnesium-adenosine triphosphate-dependent inactivators of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
1980
Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities and mRNA levels in the rat.
1992
Activation of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase by NADPH. Effects of dietary treatments.
1985
Inverse relationship between plasma cholestanol concentrations and bile acid synthesis in sitosterolemia
1994
Post-transcriptional Regulation of 3-Hydroxy-3-methylglutaryl-CoA Reductase mRNA in Rat Liver
1989
Sulfhydryl/disulfide forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase.
1985
Characteristics of rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase
1986
Regulation of cholesterol 7 alpha-hydroxylase by hepatic 7 alpha-hydroxylated bile acid flux and newly synthesized cholesterol supply.
1991
Insulin and glucagon modulate hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity by affecting immunoreactive protein levels.
1994