Citation Impact
Citing Papers
Toll Pathway-Dependent Blockade of CD4 + CD25 + T Cell-Mediated Suppression by Dendritic Cells
2003 StandoutScience
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
2007 StandoutScience
Estrogen Protects Against Cellular Infiltration by Reducing the Expressions of E-Selectin and IL-6 in Endotoxin-Induced Uveitis
1999
Cloning and Functional Expression of a Human Y4 Subtype Receptor for Pancreatic Polypeptide, Neuropeptide Y, and Peptide YY
1995
Hormone Replacement Therapy and Interrelation between Serum Interleukin-6 and Body Mass Index in Postmenopausal Women: A Population-Based Study
2000
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Characterization of mechanisms of interleukin-6 gene repression by estrogen receptor
1997
Biochemistry of growth inhibition by ammonium ions in mammalian cells
1994
Sex Hormones as Negative Regulators of Lymphopoiesis
1994
The therapeutic potential of interleukin-6 hyperagonists and antagonists
1997
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
1994 Standout
Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice.
1994
Protein phosphorylation and compartments of cyclic AMP in the control of cardiac contraction
1989
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
2012 Standout
STAT3 Activation in Stromal/Osteoblastic Cells Is Required for Induction of the Receptor Activator of NF-κB Ligand and Stimulation of Osteoclastogenesis by gp130-utilizing Cytokines or Interleukin-1 but Not 1,25-Dihydroxyvitamin D3 or Parathyroid Hormone
1999
17β-Estradiol Induces Apoptosis in the Preosteoclastic FLG 29.1 Cell Line
1999
ADRENAL AND GONADAL STEROIDS INHIBIT IL-6 SECRETION BY HUMAN MARROW CELLS
2001
Estrogen regulation of immune responses after injury
2002
Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat
1990
Interleukin-6 in Biology and Medicine
1993
DIFFERENT ROLES FOR ANDROGENS AND ESTROGENS IN THE SUSCEPTIBILITY TO AUTOIMMUNE RHEUMATIC DISEASES
2000
The PDZ Binding Motif of the β1 Adrenergic Receptor Modulates Receptor Trafficking and Signaling in Cardiac Myocytes
2002 StandoutNobel
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
1997 StandoutNature
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.
1997
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.
1997 Standout
Estrogen Inhibits Phorbol Ester-Induced IκBα Transcription and Protein Degradation
1998
Differential Effects of Estradiol on the Adrenocorticotropin Responses to Interleukin-6 and Interleukin-1 in the Monkey1
2001
Phase II trial of gemcitabine (2,2′-difiuorodeoxycytidine) in patients with adenocarcinoma of the pancreas
1994
Bone Quality — The Material and Structural Basis of Bone Strength and Fragility
2006 Standout
The function of adipocytes in the bone marrow stroma: an update
1996
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Conditioned medium of Estrogen-treated osteoblasts inhibits osteoclast maturation and function in vitro
1999
Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells.
1996
Interleukin 6 and its Receptor: Ten Years Later
1998
Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck
1998
Cytokine production in the bone marrow microenvironment: failure to demonstrate estrogen regulation in early postmenopausal women.
1996
Bone-Resorbing Cytokines from Peripheral Blood Mononuclear Cells after Hormone Replacement Therapy: A Longitudinal Study
2001
Pancreatic Adenocarcinoma
2014 Standout
Cisplatin-gemcitabine combination in advanced non-small-cell lung cancer: a phase II study.
1997
Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency.
1997
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Ectopic Expression of Nonliganded Retinoic Acid Receptor β Abrogates AP-1 Activity by Selective Degradation of c-Jun in Cervical Carcinoma Cells
2004 StandoutNobel
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
TNFα and PTH utilize distinct mechanisms to induce IL-6 and RANKL expression with markedly different kinetics
2005
Estrogen Inhibits Interleukin-lβ-Induced Interleukin-6 Production by Human Osteoblast-like Cells
1998
The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis.
1996
Metabolic Delivery of Ketone Groups to Sialic Acid Residues
1998 StandoutNobel
Uveitis and the menstrual cycle
2004
Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis
1995
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia.
1992 StandoutNobel
Cytokines, bone remodeling, and estrogen deficiency: a 1998 update
1998
Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer
2010 Standout
Estradiol Down‐Regulates LPS‐Induced Cytokine Production and NFkB Activation in Murine Macrophages
1997
Effect of oestrogen replacement on bone metabolism and cytokines in surgical menopause
1995
THE PATHOPHYSIOLOGY AND TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS
1997
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
Effects of oestrogen deprivation on interleukin-6 production by peripheral blood mononuclear cells of postmenopausal women
2002
HORMONAL ALTERATIONS IN RHEUMATOID ARTHRITIS, INCLUDING THE EFFECTS OF PREGNANCY
2000
Additive effects of suboptimal doses of estrogen and cortisone on the suppression of T lymphocyte dependent inflammatory responses in mice
1996
Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
2010 Standout
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Pancreatic Cancer
2010 Standout
Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF- B site
1997
Serum Interleukin-6 and Bone Metabolism in Patients with Thyroid Function Disorders1
1997
Estrogen enhances immunoglobulin production by human PBMCs
1999
Estrogen Modulates the Hypothalamic-Pituitary-Adrenal and Inflammatory Cytokine Responses to Endotoxin in Women1
2001
Estriol: A potent regulator of TNF and IL-6 expression in a murine model of endotoxemia
1996
Estrogen, cytokines, and the control of osteoclast formation and bone resorption in vitro and in vivo
1993
Caveolar Localization Dictates Physiologic Signaling of β2-Adrenoceptors in Neonatal Cardiac Myocytes
2002 StandoutNobel
Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption.
1998
Estrogen’s bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells
1999
Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6
1992 Science
Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor.
1995
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
Immunologic aspects of osteoporosis
1997
Immune responses and bone loss: the estrogen connection
2005
The Role of IL‐6 Type Cytokines and Their Receptors in Boneaa
1998
Adenyl cyclase and interleukin 6 are downstream effectors of parathyroid hormone resulting in stimulation of bone resorption.
1995
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Interleukin-11: a new cytokine critical for osteoclast development.
1994
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Hormonal Regulation of Osteoclast Function
1998
RAGE Mediates a Novel Proinflammatory Axis
1999 Standout
The Complex Role of Estrogens in Inflammation
2007 Standout
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
Expression of the Interleukin-6 Gene Is Constitutive and Not Regulated by Estrogen in Rat Vascular Smooth Muscle Cells in Culture*
1999
A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance.
1985
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
2011 Standout
In Vitro Secretion of Cytokines by Human Bone Marrow: Effects of Age and Estrogen Status1
1998
Interleukin 6 plays a key role in the development of antigen-induced arthritis
1998
Bone Resorption by Osteoclasts
2000 StandoutScience
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
1996 StandoutNobel
Idoxifene, a Novel Selective Estrogen Receptor Modulator, Is Effective in a Rat Model of Adjuvant-Induced Arthritis
1999
Synergistic interaction between cisplatin and gemcitabine in vitro.
1996
Estrogen Reduces the Depth of Resorption Pits by Disturbing the Organic Bone Matrix Degradation Activity of Mature Osteoclasts
2001
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
1994
Metastatic Pancreatic Cancer 2008: Is the Glass Less Empty?
2008
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes
2006 StandoutNobel
Platelet-derived growth factor stimulates the synthesis of interleukin-6 in cells of the osteoblast lineage.
1995
Compartmentation of G Protein-Coupled Signaling Pathways in Cardiac Myocytes
2001
Cellular and molecular mechanisms of osteoporosis
1998
A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors.
1999
Total Synthesis of (+)-Madindoline A and (−)-Madindoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute Configurations
2000 StandoutNobel
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
The Molecular Pharmacology of SERMs
1999
RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.
1995
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis*
2000 Standout
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
Changes in Proinflammatory Cytokine Activity after Menopause
2002
Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: a prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale.
2002
Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma
2002
Phosphodiesterase 4D is required for β 2 adrenoceptor subtype-specific signaling in cardiac myocytes
2005 StandoutNobel
Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence.
1996
Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ
1995
Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors
1996
Estrogen and progesterone induction of survival of monoblastoid cells undergoing TNF‐α‐induced apoptosis
1999
Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: Similarity to estrogen deficiency
1997
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 StandoutScience
Toremifene Increases Bone Mineral Density in Men Receiving Androgen Deprivation Therapy for Prostate Cancer: Interim Analysis of a Multicenter Phase 3 Clinical Study
2007
Discrete Microdomains with High Concentration of cAMP in Stimulated Rat Neonatal Cardiac Myocytes
2002 Science
IL-6 as a drug discovery target
1998
Simultaneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period.
1995
Endogenous bone-resorbing factors in estrogen deficiency: Cooperative effects of IL-1 and IL-6
1995
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
The Role of Estrogen Receptors and Androgen Receptors in Sex Steroid Regulation of B Lymphopoiesis
1998
Transcriptional Induction of Cyclooxygenase-2 in Osteoblasts Is Involved in Interleukin-6-Induced Osteoclast Formation*
1997
The PDZ-binding motif of the β 2 -adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes
2003 StandoutNobel
Estrogen restores cellular immunity in injured male mice via suppression of interleukin-6 production
2001
The Effects of Androgen Deficiency on Murine Bone Remodeling and Bone Mineral Density Are Mediated via Cells of the Osteoblastic Lineage*
1997
17β-Estradiol Antagonizes Effects of 1α,25-Dihydroxyvitamin D3 on Interleukin-6 Production and Osteoclast-Like Cell Formation in Mouse Bone Marrow Primary Cultures*
1997
Increased interleukin-6 production by murine bone marrow and bone cells after estrogen withdrawal.
1993
Age-Associated Increased Interleukin-6 Gene Expression, Late-Life Diseases, and Frailty
2000
Works of G B Boder being referenced
Changes in the islets of langerhans in the obese Zucker rat.
1977
Comparison of the antitumor activity of gemcitabine and ara-C in a panel of human breast, colon, lung and pancreatic xenograft models
1996
Large‐scale production of monoclonal antibodies in suspension culture
1988
17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens.
1992
Recording System for Monitoring Automaticity of Heart Cells in Culture
1971 Nature
Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).
1990
92093839 17-Estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteoporotic effect of estrogens
1992
Evidence for selective regulation of the phosphorylation of myocyte proteins by isoproterenol and prostaglandin E1
1982
Correlation of the clinical neurotoxicity of the vinca alkaloids vincristine, vinblastine, and vindesine with their effects on cultured rat midbrain cells
1979